Stoke Therapeutics, Inc. 10-K

Item 7A. Quantitative and Qualitative Disclosures About Market Risk Interest rate risk We are exposed to market risks in the ordinary course, primarily including interest sensitivities. As of December 31, 2021, we had cash, cash equivalents, marketable securities, and restricted cash of $220.4 million and $287.5 million as of December 31, 2021. Our primary exposure to market risk is interest rate sensitivity, which is affected by changes in the general level of U.S. interest rates. A hypothetical 100 basis point change in interest rates would affect the fair market value of our cash equivalents and marketable securities by approximately $2.2 million. Inflation Risk Inflation generally affects us by increasing our clinical trial costs. We do not believe that inflation has had a material effect on our business, financial condition or results of operations during the years ended December 31, 2021 or 2020. Item 8. Financial Statements and Supplementary Data. The financial statements required to be filed pursuant to this Item 8 are appended to this report. An index of those financial statements is found in Item 15 of Part IV of this Annual Report on Form 10-K. Item 9. Changes in and Disagreements With Accountants on Accounting and Financial Disclosure. None.