Offerings // Protalix BioTherapeutics, Inc.

PLX offering history

Every offering-related filing in Protalix BioTherapeutics, Inc.’s recent SEC record — registrations (announced capacity) kept separate from pricing documents (executed sales). Reviewed 962 filings back to Aug 13, 1996.

Last executed offering

Aug 22, 2025

424B5 — priced deal (shares or notes)

Last registration (announced)

Aug 14, 2025

S-3/A — capacity, not a sale

Executed, last 12 months

424B pricings + 8-K 3.02 sales

Registered, last 12 months

S-1/S-3/F-series registrations

Date	Filing		What it means
Aug 22, 2025	424B5 →	EXECUTED	Shelf takedown priced — shares or notes (small-caps: usually shares; open the filing to confirm)
Aug 22, 2025	EFFECT →	EFFECTIVE	SEC declared a registration effective — selling can begin
Aug 14, 2025	S-3/A →	REGISTERED	S-3/A registration — capacity to sell shares, not a sale yet
Apr 28, 2025	S-3 →	REGISTERED	S-3 registration — capacity to sell shares, not a sale yet
Mar 17, 2025	424B5 →	EXECUTED	Shelf takedown priced — shares or notes (small-caps: usually shares; open the filing to confirm)
Jul 7, 2023	424B3 →	UPDATE	Prospectus update — often a resale registration, not necessarily new capital
Feb 27, 2023	424B5 →	EXECUTED	Shelf takedown priced — shares or notes (small-caps: usually shares; open the filing to confirm)
May 2, 2022	424B5 →	EXECUTED	Shelf takedown priced — shares or notes (small-caps: usually shares; open the filing to confirm)
Apr 29, 2022	EFFECT →	EFFECTIVE	SEC declared a registration effective — selling can begin
Apr 20, 2022	S-3 →	REGISTERED	S-3 registration — capacity to sell shares, not a sale yet
Aug 26, 2021	8-K →	EXECUTED	Unregistered share sale disclosed (8-K item 3.02)
Aug 13, 2021	8-K →	EXECUTED	Unregistered share sale disclosed (8-K item 3.02)
Jul 2, 2021	424B5 →	EXECUTED	Shelf takedown priced — shares or notes (small-caps: usually shares; open the filing to confirm)
Jul 2, 2021	424B5 →	EXECUTED	Shelf takedown priced — shares or notes (small-caps: usually shares; open the filing to confirm)
Feb 16, 2021	424B5 →	EXECUTED	Shelf takedown priced — shares or notes (small-caps: usually shares; open the filing to confirm)
Feb 11, 2021	424B5 →	EXECUTED	Shelf takedown priced — shares or notes (small-caps: usually shares; open the filing to confirm)
Oct 1, 2020	424B5 →	EXECUTED	Shelf takedown priced — shares or notes (small-caps: usually shares; open the filing to confirm)
Apr 29, 2020	424B3 →	UPDATE	Prospectus update — often a resale registration, not necessarily new capital
Apr 29, 2020	EFFECT →	EFFECTIVE	SEC declared a registration effective — selling can begin
Apr 17, 2020	S-3 →	REGISTERED	S-3 registration — capacity to sell shares, not a sale yet
Mar 12, 2020	8-K →	EXECUTED	Unregistered share sale disclosed (8-K item 3.02)
Apr 12, 2019	EFFECT →	EFFECTIVE	SEC declared a registration effective — selling can begin
Mar 29, 2019	S-3 →	REGISTERED	S-3 registration — capacity to sell shares, not a sale yet
May 24, 2018	8-K →	EXECUTED	Unregistered share sale disclosed (8-K item 3.02)
Jul 25, 2017	8-K →	EXECUTED	Unregistered share sale disclosed (8-K item 3.02)
Dec 7, 2016	8-K →	EXECUTED	Unregistered share sale disclosed (8-K item 3.02)
Dec 18, 2015	EFFECT →	EFFECTIVE	SEC declared a registration effective — selling can begin
Nov 27, 2015	S-3/A →	REGISTERED	S-3/A registration — capacity to sell shares, not a sale yet
Nov 13, 2015	S-3 →	REGISTERED	S-3 registration — capacity to sell shares, not a sale yet
Oct 13, 2015	8-K →	EXECUTED	Unregistered share sale disclosed (8-K item 3.02)
Sep 18, 2013	8-K →	EXECUTED	Unregistered share sale disclosed (8-K item 3.02)
Feb 16, 2012	424B5 →	EXECUTED	Shelf takedown priced — shares or notes (small-caps: usually shares; open the filing to confirm)
Feb 15, 2012	424B5 →	EXECUTED	Shelf takedown priced — shares or notes (small-caps: usually shares; open the filing to confirm)
Mar 18, 2011	424B5 →	EXECUTED	Shelf takedown priced — shares or notes (small-caps: usually shares; open the filing to confirm)
Mar 17, 2011	424B5 →	EXECUTED	Shelf takedown priced — shares or notes (small-caps: usually shares; open the filing to confirm)
Jan 13, 2011	EFFECT →	EFFECTIVE	SEC declared a registration effective — selling can begin
Jan 10, 2011	S-3 →	REGISTERED	S-3 registration — capacity to sell shares, not a sale yet
Dec 22, 2008	EFFECT →	EFFECTIVE	SEC declared a registration effective — selling can begin
Dec 22, 2008	EFFECT →	EFFECTIVE	SEC declared a registration effective — selling can begin
Oct 25, 2007	S-3MEF →	REGISTERED	S-3MEF registration — capacity to sell shares, not a sale yet

PLX offering-related filings from SEC EDGAR, newest first (capped at 40). Each links to the original document.

Two honest limits. (1) A 424B takedown can price shares or notes— EDGAR’s metadata doesn’t say which, so open the document: large investment-grade filers use these mostly for bond deals (no dilution), small-caps mostly for shares. (2) At-the-market (ATM) programs sell shares gradually and individual sales are not separately filed — the visible footprint is the enabling shelf and its 424B5; actual ATM share counts surface later in the 10-Q/10-K share count. Educational information from public filings, not investment advice.

Is a shelf active now? →Do they need money? →Red flags →Full PLX workspace →

PLX offering FAQ

When did PLX last execute an offering?

Per SEC filings, Protalix BioTherapeutics, Inc.'s most recent priced offering document is a 424B5 filed 2025-08-22. Note a 424B takedown can price shares or notes (debt) — the linked document says which.

When did PLX last announce or register an offering?

The most recent registration is a S-3/A filed 2025-08-14. A registration is capacity to sell shares — not a sale.

Does an offering always mean dilution?

Registered direct offerings and shelf takedowns issue new shares and dilute existing holders. Resale registrations (424B3/B7) let existing holders sell and do not create new shares. Secondary sales by insiders also do not dilute. Each row here is labeled with what it is.