Offerings // Karyopharm Therapeutics Inc.

KPTI offering history

Every offering-related filing in Karyopharm Therapeutics Inc.’s recent SEC record — registrations (announced capacity) kept separate from pricing documents (executed sales). Reviewed 1,001 filings back to Jan 7, 2015.

Last executed offering

Mar 24, 2026

8-K — priced deal (shares or notes)

Last registration (announced)

May 4, 2026

S-3 — capacity, not a sale

Executed, last 12 months

424B pricings + 8-K 3.02 sales

Registered, last 12 months

S-1/S-3/F-series registrations

Date	Filing		What it means
May 14, 2026	EFFECT →	EFFECTIVE	SEC declared a registration effective — selling can begin
May 14, 2026	EFFECT →	EFFECTIVE	SEC declared a registration effective — selling can begin
May 4, 2026	S-3 →	REGISTERED	S-3 registration — capacity to sell shares, not a sale yet
May 4, 2026	S-3 →	REGISTERED	S-3 registration — capacity to sell shares, not a sale yet
Mar 24, 2026	8-K →	EXECUTED	Unregistered share sale disclosed (8-K item 3.02)
Nov 24, 2025	424B3 →	UPDATE	Prospectus update — often a resale registration, not necessarily new capital
Nov 24, 2025	424B3 →	UPDATE	Prospectus update — often a resale registration, not necessarily new capital
Nov 3, 2025	S-3 →	REGISTERED	S-3 registration — capacity to sell shares, not a sale yet
Nov 3, 2025	S-3 →	REGISTERED	S-3 registration — capacity to sell shares, not a sale yet
Oct 8, 2025	8-K →	EXECUTED	Unregistered share sale disclosed (8-K item 3.02)
Jun 7, 2024	EFFECT →	EFFECTIVE	SEC declared a registration effective — selling can begin
May 30, 2024	S-3 →	REGISTERED	S-3 registration — capacity to sell shares, not a sale yet
May 8, 2024	8-K →	EXECUTED	Unregistered share sale disclosed (8-K item 3.02)
May 5, 2023	EFFECT →	EFFECTIVE	SEC declared a registration effective — selling can begin
Feb 17, 2023	S-3 →	REGISTERED	S-3 registration — capacity to sell shares, not a sale yet
Jan 3, 2023	EFFECT →	EFFECTIVE	SEC declared a registration effective — selling can begin
Dec 23, 2022	S-3 →	REGISTERED	S-3 registration — capacity to sell shares, not a sale yet
Dec 5, 2022	8-K →	EXECUTED	Unregistered share sale disclosed (8-K item 3.02)
Aug 5, 2021	S-3ASR →	REGISTERED	Automatic shelf registration — effective immediately (large filers)
May 5, 2020	424B5 →	EXECUTED	Shelf takedown priced — shares or notes (small-caps: usually shares; open the filing to confirm)
Mar 4, 2020	424B5 →	EXECUTED	Shelf takedown priced — shares or notes (small-caps: usually shares; open the filing to confirm)
Mar 2, 2020	424B5 →	EXECUTED	Shelf takedown priced — shares or notes (small-caps: usually shares; open the filing to confirm)
Feb 26, 2020	S-3ASR →	REGISTERED	Automatic shelf registration — effective immediately (large filers)
May 10, 2019	424B5 →	EXECUTED	Shelf takedown priced — shares or notes (small-caps: usually shares; open the filing to confirm)
Apr 24, 2019	EFFECT →	EFFECTIVE	SEC declared a registration effective — selling can begin
Oct 16, 2018	8-K →	EXECUTED	Unregistered share sale disclosed (8-K item 3.02)
Aug 17, 2018	424B5 →	EXECUTED	Shelf takedown priced — shares or notes (small-caps: usually shares; open the filing to confirm)
Jul 2, 2018	S-3ASR →	REGISTERED	Automatic shelf registration — effective immediately (large filers)
May 3, 2018	424B5 →	EXECUTED	Shelf takedown priced — shares or notes (small-caps: usually shares; open the filing to confirm)
May 1, 2018	424B5 →	EXECUTED	Shelf takedown priced — shares or notes (small-caps: usually shares; open the filing to confirm)
Feb 14, 2018	EFFECT →	EFFECTIVE	SEC declared a registration effective — selling can begin
Feb 7, 2018	S-3/A →	REGISTERED	S-3/A registration — capacity to sell shares, not a sale yet
Jan 26, 2018	S-3 →	REGISTERED	S-3 registration — capacity to sell shares, not a sale yet
Dec 1, 2017	424B5 →	EXECUTED	Shelf takedown priced — shares or notes (small-caps: usually shares; open the filing to confirm)
Apr 26, 2017	424B5 →	EXECUTED	Shelf takedown priced — shares or notes (small-caps: usually shares; open the filing to confirm)
Apr 24, 2017	424B5 →	EXECUTED	Shelf takedown priced — shares or notes (small-caps: usually shares; open the filing to confirm)
Dec 1, 2016	EFFECT →	EFFECTIVE	SEC declared a registration effective — selling can begin
Nov 8, 2016	424B5 →	EXECUTED	Shelf takedown priced — shares or notes (small-caps: usually shares; open the filing to confirm)
Nov 8, 2016	S-3 →	REGISTERED	S-3 registration — capacity to sell shares, not a sale yet
May 19, 2016	424B5 →	EXECUTED	Shelf takedown priced — shares or notes (small-caps: usually shares; open the filing to confirm)

KPTI offering-related filings from SEC EDGAR, newest first (capped at 40). Each links to the original document.

Two honest limits. (1) A 424B takedown can price shares or notes— EDGAR’s metadata doesn’t say which, so open the document: large investment-grade filers use these mostly for bond deals (no dilution), small-caps mostly for shares. (2) At-the-market (ATM) programs sell shares gradually and individual sales are not separately filed — the visible footprint is the enabling shelf and its 424B5; actual ATM share counts surface later in the 10-Q/10-K share count. Educational information from public filings, not investment advice.

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KPTI offering FAQ

When did KPTI last execute an offering?

Per SEC filings, Karyopharm Therapeutics Inc.'s most recent priced offering document is a 8-K filed 2026-03-24. Note a 424B takedown can price shares or notes (debt) — the linked document says which.

When did KPTI last announce or register an offering?

The most recent registration is a S-3 filed 2026-05-04. A registration is capacity to sell shares — not a sale.

Does an offering always mean dilution?

Registered direct offerings and shelf takedowns issue new shares and dilute existing holders. Resale registrations (424B3/B7) let existing holders sell and do not create new shares. Secondary sales by insiders also do not dilute. Each row here is labeled with what it is.