Item 1B. Unresolved Staff Comments
ITEM
1B. Unresolved
Staff Comments
We
do not have any unresolved comments issued by the SEC Staff.
ITEM
1C. Cybersecurity
Risk
Management and Strategy
We
have established policies and processes for assessing, identifying, and managing material risk from cybersecurity threats, and have integrated
these processes into our overall risk management systems and processes. We monitor cybersecurity threats, including any potential unauthorized
occurrence on or conducted through our information systems that we use through third party providers that may result in adverse effects
on the confidentiality, integrity, or availability of our information systems or any information residing therein.
We
engage consultants in connection with our risk assessment processes. These service providers assist us in designing and implementing
our cybersecurity policies and procedures, as well as monitoring and testing our safeguards. We require each third-party service provider
to certify that it has the ability to implement and maintain appropriate security measures, consistent with all applicable laws, to implement
and maintain reasonable security measures in connection with their work with us, and to promptly report any suspected breach of its security
measures that may affect our company.
As
of December 31, 2025, and through the date of the filing of this report, we are no t aware of any cybersecurity incidents that have materially
affected or are reasonably likely to materially affect us, including our business strategy, results of operations or financial condition.
For additional information regarding risks from cybersecurity threats, please refer to Item 1A, “Risk Factors,” in this 2025
Annual Report.
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Governance
One
of the key functions of our board of directors is informed oversight of our risk management process, including risks from cybersecurity
threats. Our board of directors is responsible for monitoring and assessing strategic risk exposure, and our executive officers are responsible
for the day-to-day management of the material risks we face. Our board of directors administers its cybersecurity risk oversight function
through its audit committee, which provides oversight of our cybersecurity program as part of its periodic review of enterprise risk
management .
Our
President and Chief Executive Officer and Senior Vice President of Finance are primarily responsible for assessing and managing our material
risks from cybersecurity threats. In this regard, our President and Chief Executive Officer and Senior Vice President of Finance have
assistance from consultants.
Our
President and Chief Executive Officer and Senior Vice President of Finance oversee our cybersecurity policies and processes, including
those described in “Risk Management and Strategy” above. Under such policies and processes, our President and Chief Executive
Officer and Senior Vice President are responsible for reporting to our audit committee regarding any cybersecurity incidents.
The
audit committee, in turn, provides periodic reports to our board of directors regarding our cybersecurity processes, including the results
of cybersecurity risk assessments.
ITEM 2.
Properties
We
currently lease approximately 4,000 square feet of office and laboratory space in New York and Massachusetts. The term of our Manhattan
lease was to expire in January 2027, but we entered into a lease termination agreement with the landlord, effective March 13, 2026. See
Note 18 to the consolidated financial statement for more information regarding the lease termination agreement. The term of our Massachusetts
lease expires in June 2028. We believe that our leased property is generally well maintained, in good operating condition and meets our
current business needs.
ITEM
3. Legal
Proceedings
For
a description of our legal proceedings, refer to Note 13 to the consolidated financial statements, which is incorporated herein by reference.
ITEM
4. Mine
Safety Disclosures
Not
Applicable.
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PART
II