REPLIGEN CORP 10-Q

ITEM 2. UNREGISTERED SALES OF EQU ITY SECURITIES AND USE OF PROCEEDS None. ITEM 3. DEFAULTS UPON SEN IOR SECURITIES None. ITEM 4. MINE SAFETY DI SCLOSURES Not applicable. ITEM 5. OTHER INF ORMATION None. 39 ITEM 6. EXHI BITS (a) Exhibits Exhibit Number Document Description 3.1 Restated Certificate of Incorporation, dated June 30, 1992 and amended September 17, 1999 (filed as Exhibit 3.1 to Repligen Corporation’s Quarterly Report on Form 10-Q for the quarter ended September 30, 1999 and incorporated herein by reference). 3.2 Certificate of Amendment to the Certificate of Incorporation of Repligen Corporation, effective as of May 16, 2014 (filed as Exhibit 3.1 to Repligen Corporation’s Current Report on Form 8-K filed on May 19, 2014 and incorporated herein by reference) . 3.3 Third Amended and Restated Bylaws (filed as Exhibit 3.1 to Repligen Corporation’s Current Report on Form 8-K filed on January 28, 2021 and incorporated herein by reference). 4.1 Second Supplemental Indenture, dated as of March 4, 2022, by and between Repligen Corporation and Wilmington Trust, National Association, as trustee (filed as Exhibit 4.1 to Repligen Corporation's Current Report on Form 8-K filed on March 8, 2022 and incorporated herein by reference). 31.1 + Rule 13a-14(a)/15d-14(a) Certification. 31.2 + Rule 13a-14(a)/15d-14(a) Certification. 32.1 * Certification pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002. 101.INS+ XBRL Instance Document – the instance document does not appear in the Interactive Data File because its XBRL tags are embedded within the Inline XBRL document. 101.SCH+ Inline XBRL Taxonomy Extension Schema Document. 101.CAL+ Inline XBRL Taxonomy Extension Calculation Linkbase Document. 101.DEF+ Inline XBRL Taxonomy Extension Definition Linkbase Document. 101.LAB+ Inline XBRL Taxonomy Extension Label Linkbase Document. 101.PRE+ Inline XBRL Taxonomy Extension Presentation Linkbase Document. 104+ Cover Page Interactive Data File (formatted as Inline XBRL with applicable taxonomy extension information contained in Exhibits 101.*). + Filed herewith. * Furnished herewith. 40 SIGNAT URES Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized. REPLIGEN CORPORATION Date: April 27, 2022 By: / S / T ONY J. H UNT Tony J. Hunt President and Chief Executive Officer (Principal executive officer) Repligen Corporation Date: April 27, 2022 By: / S / J ON S NODGRES Jon Snodgres Chief Financial Officer (Principal financial officer) Repligen Corporation 41