2 unchanged sentences
Our Chief Executive Officer, President and General
−Removed: Counsel, as our principal executive officer (“Chief Executive Officer”), and our Chief Financial Officer, as our principal
−Removed: financial officer (“Chief Financial Officer”), evaluated the effectiveness of our “disclosure controls and procedures,”
+Added: Counsel, as our principal executive officer (“Chief Executive Officer”), and our Chief Financial Officer, as our principal
+Added: financial officer (“Chief Financial Officer”), evaluated the effectiveness of our “disclosure controls and procedures,”
as such term is defined in Rule 13a-15(e) promulgated under the Exchange Act.
1 unchanged sentence
that the information required to be disclosed in the reports that we file or submit to the Commission pursuant to the Exchange Act are
−Removed: recorded, processed, summarized and reported within the period specified by the Commission’s rules and forms and are accumulated
+Added: recorded, processed, summarized and reported within the period specified by the Commission’s rules and forms and are accumulated
and communicated to our management, including our Chief Executive Officer, as appropriate to allow timely decisions regarding required
Based upon this evaluation, our Chief Executive Officer and our Chief Financial Officer have concluded that, as of April
−Removed: 30, 2021, our disclosure controls and procedures were not effective due to the material weaknesses in internal control over financial
−Removed: reporting, below described in Management’s Report on Internal Control over Financial Reporting.
+Added: 30, 2022, that certain of our disclosure controls and procedures were not effective due to the material weaknesses in internal control
+Added: over financial reporting.
+Added: This is described below in Management’s Report on Internal Control over Financial Reporting.
A control system, no matter how well conceived
12 unchanged sentences
assurance that any design will succeed in achieving its stated goals under all potential future conditions.
−Removed: Management’s Report on Internal Controls
+Added: Management’s Report on Internal Controls
over Financial Reporting
2 unchanged sentences
Our internal controls over financial reporting are designed to provide reasonable assurance regarding the reliability of financial reporting
−Removed: and the preparation of financial statements for external purposes in accordance with accounting principles generally accepted in the United
−Removed: States of America (“U.S.
−Removed: GAAP”).
+Added: and the preparation of financial statements for external purposes in accordance with U.S.
A material weakness is a deficiency, or a combination
of deficiencies, in internal controls over financial reporting such that there is a reasonable possibility that a material misstatement
−Removed: of the company’s annual or interim financial statements will not be prevented or detected in a timely basis.
+Added: of our annual or interim financial statements will not be prevented or detected in a timely basis.
Under the supervision and with the participation
1 unchanged sentence
controls over financial reporting as of April 30, 2022, based on the criteria outlined in Internal Control-Integrated Framework (2013)
−Removed: issued by the Committee of Sponsoring Organizations of the Treadway Commission (“COSO”) and identified the following material
+Added: issued by the Committee of Sponsoring Organizations of the Treadway Commission (“COSO”) and identified the following material
weaknesses in internal controls over financial reporting:
1 unchanged sentence
We have delegated some of the duties of our Chief Financial Officer to other personnel within the Company and have added review and approval processes performed by the Chief Executive Officer.
−Removed: However, we have determined that we still have insufficient segregation of the duties of our Chief Financial Officer and will continue to review these procedures to determine ways to further improve them given our limited staff.
−Removed: Insufficient information technology controls and documentation.
−Removed: We currently use accounting software which we have determined is inadequate to provide the level of controls required by COSO.
−Removed: We are in the process of initiating a review process to fully evaluate the deficiencies in our technology controls and documentation.
−Removed: Based upon the results of this review process, we intend to implement the required remediation measures when it is reasonable to do so.
−Removed: Because of these material weaknesses, our Chief
−Removed: Executive Officer and our Chief Financial Officer concluded that, as of April 30, 2021, our internal controls over financial reporting
−Removed: were not effective based on the COSO criteria.
−Removed: We are in the process of investigating new procedures
−Removed: and controls for fiscal year 2022.
−Removed: We plan to make changes to our procedures and controls that we believe are reasonably likely to strengthen
−Removed: and materially affect our internal controls over financial reporting.
−Removed: Prior to the remediation of these material weaknesses,
+Added: However, we have determined that we still have insufficient segregation of the duties of our Chief Financial Officer.
+Added: We plan to hire an additional person to work for our Chief Financial Officer to enable sufficient segregation of his duties.
+Added: Because of this material weakness, our Chief Executive
+Added: Officer and our Chief Financial Officer concluded that, as of April 30, 2022, our internal controls over financial reporting were not
+Added: effective based on the COSO criteria.
+Added: We plan to make changes to our procedures and
+Added: controls that we believe are reasonably likely to strengthen and materially affect our internal controls over financial reporting.
+Added: one material weakness should be eliminated during fiscal year 2023.
+Added: Prior to the remediation of our material weakness,
there remains risk that the processes and procedures on which we currently rely will fail to be sufficiently effective, which could result
16 unchanged sentences
Remediation of a Material Weakness
−Removed: Throughout the year ended
−Removed: April 30, 2021, the Company undertook remediation measures related to a previously reported material weakness in internal control over
−Removed: financial reporting.
−Removed: The previously reported material weakness related to insufficient procedures and control documentation including
−Removed: lack of timely contract preparation and review by qualified personnel and management.
−Removed: We completed this remediation measures during the
−Removed: year ended April 30, 2021, including testing of the design and implementation of the related controls.
−Removed: Specifically, we implemented a
−Removed: more rigorous process to provide ample review time of financial information, including contract preparation and review by qualified personnel
−Removed: as well as management.
−Removed: Based on these procedures, we believe that the previously reported material weakness has been remediated.
+Added: Throughout the year ended April 30, 2022, we undertook
+Added: remediation measures related to a previously reported material weakness in internal control over financial reporting.
+Added: The previously reported
+Added: material weakness related to insufficient information technology controls and documentation.
+Added: We completed the remediation measures during
+Added: the year ended April 30, 2022, including testing of the design and implementation of the related controls.
+Added: We acquired and installed an
+Added: accounting software package to record our transactions to provide the level of controls required by COSO.
+Added: Based on these procedures, we
+Added: believe that this previously reported material weakness has been remediated.
Changes in Internal Controls over Financial
−Removed: Other than described
−Removed: above in this Item 9A, there were no changes to our internal control over financial reporting during the fiscal year ended April 30, 2021
−Removed: that have materially affected, or are reasonably likely to materially affect, our internal controls over financial reporting.
+Added: Other than described above in this Item 9A, there
+Added: were no changes to our internal control over financial reporting during the fiscal year ended April 30, 2022, that have materially affected,
+Added: or are reasonably likely to materially affect, our internal controls over financial reporting.
The Certifications of our Principal Executive
and Principal Financial Officer required in accordance with Rule 13a-14(a) under the Exchange Act and Section 302 of the Sarbanes-Oxley
−Removed: Act of 2002 (“Certifications”) are attached to this Report.
+Added: Act of 2002 (“Certifications”) are attached to this Report.
The disclosures set forth in this Item 9A contain information
6 unchanged sentences
OTHER INFORMATION
+Added: On May 8, 2022, we entered into amendments to
+Added: the employment agreements with each of Kenneth L.
+Added: Waggoner, our Chief Executive Officer and President, and Carlos A.
+Added: Trujillo, our Chief
+Added: Financial Officer.
+Added: The terms of such amended employment agreements are summarized in Part III, Item 11.
+Added: “Executive Compensation—Employment
+Added: Arrangements” of this Report, which summaries are qualified in their entirety by reference to the full text of such amended employment
+Added: agreements filed herewith as Exhibits 10.40 and 10.41.
+Added: DISCLOSURE REGARDING FOREIGN JURISDICTIONS
+Added: THAT PREVENT INSPECTIONS
+Added: Not applicable.
DIRECTORS, EXECUTIVE OFFICERS AND
CORPORATE GOVERNANCE
−Removed: As of August 9, 2021, our directors and executive
+Added: As of July 15, 2022, our directors and executive
officers are:
Chairman of the Board, Chief Executive Officer, President and General Counsel
−Removed: Crabtree, PhD.
Director and Chief Scientific Officer
−Removed: Trujillo, CPA
Director and Chief Financial Officer
Thomas Liquard
−Removed: Abecassis, MD
−Removed: He became our Chief Executive Officer and President
−Removed: in November 2013.
+Added: Matthias Löhr
+Added: Waggoner became our Chief Executive
+Added: Officer and President in November 2013.
Shortly thereafter, Mr.
Waggoner assumed the additional position of General Counsel.
−Removed: In April 2014, Mr.
−Removed: Waggoner became
−Removed: a full-time employee as the Chief Executive Officer, President and General Counsel of both PharmaCyte and Viridis Biotech, a wholly owned
−Removed: subsidiary of PharmaCyte.
+Added: Waggoner became a full-time employee as the Chief Executive Officer, President and General Counsel of both PharmaCyte and Viridis
+Added: Biotech, a wholly owned subsidiary of PharmaCyte.
Waggoner has been a member of the Board since September 2014.
−Removed: Waggoner has over forty-five years of
−Removed: experience in management, business, operations and the practice of law.
−Removed: It was his education, training, experience and leadership skills
−Removed: that led us to elect him to the Board and appoint him Chairman.
+Added: Waggoner has over
+Added: forty-five years of experience in management, business, operations and the practice of law.
+Added: It was his education, training, experience
+Added: and leadership skills that led us to elect him to the Board and appoint him Chairman.
Waggoner began his professional career as
an attorney in private practice.
−Removed: From 1986 to 2003, he was a senior partner with Brobeck, Phleger and Harrison (“Brobeck”),
−Removed: where he was the Managing Partner of Brobeck’s Los Angeles office.
+Added: From 1986 to 2003, he was a senior partner with the international law firm Brobeck, Phleger and Harrison
+Added: He was the Managing Partner of Brobeck’s Los Angeles office.
While at Brobeck, Mr.
−Removed: Waggoner served as a member of the Executive
−Removed: Committee and on the Policy Committee.
−Removed: Waggoner was the co-Chairman of Brobeck’s worldwide Environmental Law Group.
−Removed: Waggoner’s career included leadership
+Added: Waggoner served as a
+Added: member of the Executive Committee and Policy Committee.
+Added: Waggoner was the co-Chairman of Brobeck’s worldwide Environmental Law
+Added: Waggoner’s career included leadership
and legal positions with Fortune 100 companies most of his professional career.
1 unchanged sentence
Waggoner served as the Vice President
−Removed: and General Counsel of Chevron’s global downstream operations where he was responsible for the overall management of legal services
+Added: and General Counsel of Chevron’s global downstream operations where he was responsible for the overall management of legal services
to the North American, Latin American, European and Asian Products Companies.
While at Chevron, Mr.
−Removed: Waggoner led the successful restructuring
−Removed: of Chevron’s global Legal Department following Chevron’s acquisition of Texaco.
+Added: Waggoner led the restructuring of
+Added: Chevron’s global Legal Department following Chevron’s acquisition of Texaco.
From 2005 until September 2013, Mr.
5 unchanged sentences
honors from Loyola University School of Law in Los Angeles in 1973.
−Removed: Crabtree, PhD
Crabtree is our Chief Scientific Officer
1 unchanged sentence
He has served as Chief Scientific Officer since October 14, 2020.
+Added: Prior to that,
Crabtree was our Chief Operating Officer.
−Removed: Given the major importance to developing treatments for cancer and diabetes
−Removed: coupled with Dr.
−Removed: Crabtree’s education, training and experience, Dr.
+Added: Given the major importance to developing treatments for cancer and diabetes coupled with
+Added: Crabtree’s education, training and experience, Dr.
Crabtree was appointed to the Board.
−Removed: Crabtree’s background in the biomedical
+Added: Crabtree’s background in the biomedical
sciences has been substantial, having been involved with various biopharmaceutical companies where he has alternatively supervised and
1 unchanged sentence
and review articles.
−Removed: Crabtree has over 50 years of experience in the biomedical sciences sector with the majority of that being in the cancer area.
−Removed: served as the Director of Project Planning and Management (Oncology and Immunology) at Bristol-Myers Squibb (“BMS”) from 1990
+Added: Crabtree has over 50 years of experience in
+Added: the biomedical sciences sector with the majority of that being in the cancer area.
+Added: Crabtree served as the Director of Project Planning
+Added: and Management (Oncology and Immunology) at Bristol-Myers Squibb (“BMS”) from 1990 to 1997.
While at BMS, Dr.
−Removed: Crabtree established and directed the department that coordinated the development of all oncologic and immunologic
−Removed: drugs from initial discovery through regulatory approval.
−Removed: He also served as Project Manager for the development of the major anticancer
−Removed: agent, Taxol.
−Removed: Taxol ultimately became a multi-billion-dollar drug for BMS and is still widely used to treat a variety of cancers.
−Removed: 1985 to 1990, Dr.
−Removed: Crabtree was the Director of Pharmacology at Viratek, a subsidiary of ICN Pharmaceuticals, in Costa Mesa, California,
−Removed: where he worked on the development of anticancer drugs first developed at the Nucleic Acid Research Institute, a joint venture between
−Removed: Eastman Kodak and ICN Pharmaceuticals.
−Removed: He also helped coordinate the development of ribavirin, Viratek's landmark antiviral drug.
−Removed: 1970 through 1985, Dr.
−Removed: Crabtree was a member of the faculty of Brown University where he was involved in both basic and clinical cancer
−Removed: Crabtree received
−Removed: in Biochemistry from the University of Alberta, Edmonton, Alberta, Canada, and has published over 80 articles in peer-reviewed
−Removed: He was a National Cancer Institute of Canada Research Fellow, is currently a member of the American Society of Clinical Oncology
−Removed: and was a member of the American Association for Cancer Research from the early 1990s until recently and has served on research grant
−Removed: review committees for the National Institutes of Health and the American Cancer Society.
−Removed: Trujillo, CPA
−Removed: Trujillo has been our Chief
−Removed: Financial Officer and a member of the Board since March 2017.
+Added: Crabtree established
+Added: and directed the department that coordinated the development of all oncologic and immunologic drugs from initial discovery through regulatory
+Added: He also served as Project Manager for the development of the major anticancer agent, Taxol.
+Added: Taxol ultimately became a multi-billion-dollar
+Added: drug for BMS and is still widely used to treat a variety of cancers.
+Added: From 1985 to 1990, Dr.
+Added: Crabtree was the Director of Pharmacology
+Added: at Viratek, a subsidiary of ICN Pharmaceuticals, in Costa Mesa, California, where he worked on the development of anticancer drugs first
+Added: developed at the Nucleic Acid Research Institute, a joint venture between Eastman Kodak and ICN Pharmaceuticals.
+Added: He also helped coordinate
+Added: the development of ribavirin, Viratek's landmark antiviral drug.
+Added: From 1970 through 1985, Dr.
+Added: Crabtree was a member of the faculty of Brown
+Added: University where he was involved in both basic and clinical cancer research.
+Added: Crabtree received his Ph.D.
+Added: in Biochemistry
+Added: from the University of Alberta, Edmonton, Alberta, Canada, and has published over 80 articles in peer-reviewed journals.
+Added: He was a National
+Added: Cancer Institute of Canada Research Fellow, is currently a member of the American Society of Clinical Oncology and was a member of the
+Added: American Association for Cancer Research from the early 1990s until recently and has served on research grant review committees for the
+Added: National Institutes of Health and the American Cancer Society.
+Added: Trujillo has been our Chief Financial
+Added: Officer and a member of the Board since March 2017.
He began working for us as an independent contractor in September 2014.
−Removed: In January 2015, Mr.
−Removed: Trujillo became a full-time employee as the Vice President of Finance of both us and Viridis Biotech, and
−Removed: in March 2017, Mr.
+Added: Trujillo became a full-time employee as the Vice President of Finance of both us and Viridis Biotech, and in March 2017, Mr.
Trujillo was appointed as our Chief Financial Officer.
−Removed: Trujillo has over three decades of experience in management, business, operations and financial accounting.
−Removed: education, experience and leadership skills that led us to elect him to the Board.
+Added: Trujillo has over three decades of experience in management, business, operations
+Added: and financial accounting.
+Added: It was his education, experience and leadership skills that led us to elect him to the Board.
Trujillo is a Certified Public Accountant
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Trujillo was the Chief Financial Officer of VelaTel Global Communications, Inc.
−Removed: As a result, he brings extensive experience
−Removed: to us in preparing and filing periodic reports with the Commission, in mergers and acquisitions and in the filing of comprehensive financial
+Added: As a result, he brings experience to us in preparing
+Added: and filing periodic reports with the Commission, in mergers and acquisitions and in the filing of comprehensive financial statements.
Trujillo received his Bachelor of Accounting
3 unchanged sentences
since April 2015.
−Removed: Liquard has more than 15 years of experience in the pharmaceutical industry,
−Removed: having held various commercialization, product development and leadership roles with large pharmaceutical and biotechnology companies .
−Removed: currently serves as the Senior Vice President of Product Development at Neurelis, Inc., a San Diego based biotechnology company.
−Removed: Neurelis in late 2017.
−Removed: He From August 2015 to August 2017, Mr.
−Removed: Liquard was the Chief Executive Officer of Immuron, a Melbourne, Australia-based
−Removed: pharmaceutical company.
+Added: Liquard has more than 15 years of experience in the pharmaceutical industry, having held various commercialization,
+Added: product development and leadership roles with large pharmaceutical and biotechnology companies.
+Added: Liquard currently serves as the Senior Vice
+Added: President of Product Development at Neurelis, Inc., a San Diego based biotechnology company.
+Added: He joined Neurelis in late 2017.
+Added: August 2015 to August 2017, Mr.
+Added: Liquard was the Chief Executive Officer of Immuron, a Melbourne, Australia-based pharmaceutical company.
Prior to Immuron, Mr.
−Removed: Liquard served as the Chief Executive Officer and Chief Operating Officer of Alchemia, a
−Removed: major Australian pharmaceutical company.
+Added: Liquard served as the Chief Executive Officer and Chief Operating Officer of Alchemia, a major Australian pharmaceutical
Liquard worked for Alchemia from October 2013 to November 2014.
−Removed: Liquard spent the previous
−Removed: seven years with Pfizer, Inc.
+Added: Liquard spent the previous seven years with Pfizer, Inc.
based in New York, where he held various senior commercial positions.
−Removed: His last was as Senior Director, Portfolio
−Removed: Development Leader and Emerging Markets for the Established Products portfolio.
+Added: His last was as Senior Director, Portfolio Development Leader and
+Added: Emerging Markets for the Established Products portfolio.
In that role, Mr.
−Removed: Liquard drove business development (M&A,
−Removed: licensing, partnerships) and internal product development initiatives.
+Added: Liquard drove business development (M&A, licensing, partnerships)
+Added: and internal product development initiatives.
Liquard was appointed to the Board because
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We believed that his
−Removed: seven-year tenure with Pfizer, one of the world’s leading pharmaceutical companies, where he played leading roles in the development
−Removed: of that company’s portfolio development, was a needed asset to us.
+Added: seven-year tenure with Pfizer, one of the world’s leading pharmaceutical companies, where he played leading roles in the development
+Added: of that company’s portfolio development, was a needed asset to us.
Liquard received his Master of Business Administration in
Finance and Strategy from the Columbia Business School and a Bachelor of Science degree from the University of Southern California.
−Removed: Yuen was appointed to the Board in
−Removed: Yuen has more than three decades of experience in entrepreneurship and business leadership, including in the biotech industry.
−Removed: It was his stellar career in business, leadership skills and business acumen and experience that led us to elect him to the Board.
−Removed: Yuen’s career is exemplified by his
−Removed: global entrepreneurial experience.
−Removed: He co-founded Irvine-based AST Research, Inc.
−Removed: (“AST”) in 1981.
−Removed: AST was an early pioneer
−Removed: of the computer industry, and the company has been referred to as “the flagship of innovation in the PC era.”
−Removed: as AST's Co-Chairman and Chief Operating Officer from August 1987 to June 1992.
−Removed: Under his leadership, AST became a Fortune 500 company
−Removed: in 1991, and its stock was named the “Best Performing NASDAQ Stock”
−Removed: of that year.
−Removed: Yuen left AST in 1992 and focused his efforts
−Removed: on investing in new projects.
−Removed: Yuen served in various engineering and project management positions with Hughes Aircraft Company, Sperry
−Removed: Univac and Computer Automation.
−Removed: Later in his career, Mr.
−Removed: Yuen became Chairman and CEO of SRS Labs, a world leader in audio and voice technology.
−Removed: Currently, Mr.
−Removed: Yuen is Chairman and Chief Executive Officer of PrimeGen Biotech, LLC, a private cell therapy company he founded in 2002.
−Removed: Yuen has held numerous director positions.
−Removed: He served as a Director of AST from 1981 to June 1992.
−Removed: He served as a Director of Valence Technology, Inc., an energy storage company,
−Removed: from March 1998 to March 2000 and a Director of DTS, Inc., an audio technology company, from April 2012 to July 2013.
−Removed: Yuen has served
−Removed: as a Director of SRS Labs since January 1994.
−Removed: He is also an Honorary Professor of China Nationality University in Beijing.
−Removed: In 1988 and 1991, the Computer Reseller News Magazine
−Removed: Yuen one of the top 25 executives of the computer industry.
−Removed: In 1997, he received the Director of the Year Award from the Orange
−Removed: County Foundation of Corporate Directors.
−Removed: Yuen is the recipient of several awards from the University of California, Irvine (“UCI”),
−Removed: including the UCI Medal in 1990, the Outstanding Engineering Alumni Award in 1987 and the Distinguished Alumnus Award in 1986.
−Removed: Yuen has received the prestigious UCI Extraordinarious Award for his exemplary career in business and his philanthropic and volunteer
−Removed: received his Bachelor of Science degree in Electrical Engineering from the University of California, Irvine.
−Removed: Abecassis, MD
−Removed: Abecassis was appointed to the Board in
+Added: Abecassis, MD was appointed to the
+Added: Board in July 2017.
Since November 2019, Dr.
−Removed: Abecassis has been Dean of the University of Arizona College of Medicine –
−Removed: to that and since 1992, Dr.
+Added: Abecassis has been Dean of the University of Arizona College of Medicine – Tucson.
+Added: Prior to that and since 1992, Dr.
Abecassis was a transplantation surgeon at the Northwestern University Feinberg School of Medicine.
1 unchanged sentence
career in medicine.
−Removed: attributes and his extensive experience in the medical field translate directly to the work being undertaken by us in the
−Removed: cancer arena.
+Added: These attributes and his experience in the medical field translate directly to the work being undertaken by us in
+Added: the cancer arena and have led us to elect him to the Board.
Abecassis was the Director of the Comprehensive
Transplant Center of the Feinberg School of Medicine.
−Removed: He was also the Chief of Transplant Surgery in the Department of Surgery at
−Removed: Feinberg and a James Roscoe Miller Distinguished Professor of Medicine at Feinberg.
+Added: He was also the Chief of Transplant Surgery in the Department of Surgery at Feinberg
+Added: and a James Roscoe Miller Distinguished Professor of Medicine at Feinberg.
Abecassis received his Medical Degree from
5 unchanged sentences
Abecassis became Northwestern
−Removed: University’s Director of Liver Transplantation, where he initiated Northwestern’s liver transplant program.
+Added: University’s Director of Liver Transplantation, where he initiated Northwestern’s liver transplant program.
was named Chief of the Division of Transplantation at the Feinberg School of Medicine.
2 unchanged sentences
Abecassis has received continuous funding
−Removed: from the National Institutes of Health (“NIH”) for the past 17 years.
+Added: from the National Institutes of Health (“NIH”) for the past 17 years.
He is the principal investigator in research that includes
14 unchanged sentences
American Society of Transplant Surgeons Leadership Development Program since 2010 and was course director for the Advanced Leader Development
−Removed: Program in 2013 at Northwestern’s Kellogg School of Management.
+Added: Program in 2013 at Northwestern’s Kellogg School of Management.
He was a voting member of the Medicare Coverage Advisory Committee
and served on the United HealthCare Group Physician Advisory Board on Healthcare Performance and Quality.
−Removed: Abecassis has been
−Removed: a member of various local, regional and national regulatory committees and has published seminal papers on both the regulatory and financial
−Removed: aspects of transplantation, including the Healthcare Reform and the Affordable Care Act.
−Removed: Raymond C.K Tong, MD
−Removed: Tong serves as Chief Executive Officer of
−Removed: Harmony Medical Inc., an Asian investment group active in the introduction and distribution of medical and healthcare products and services
−Removed: in China and throughout Asia.
−Removed: He is also Chairman of the Business Development Committee of Shanghai Kedu Healthcare Group, the largest
−Removed: medical equipment third-party service provider in China, representing products from GE, Philips, Siemens, Kodak and other multi-nationals
−Removed: as well as local companies.
+Added: Abecassis has been a member
+Added: of various local, regional and national regulatory committees and has published seminal papers on both the regulatory and financial aspects
+Added: of transplantation, including the Healthcare Reform and the Affordable Care Act.
+Added: Raymond C.K Tong
+Added: Tong, MD serves as Chief Executive
+Added: Officer of Harmony Medical Inc., an Asian investment group active in the introduction and distribution of medical and healthcare products
+Added: and services in China and throughout Asia.
+Added: He is also Chairman of the Business Development Committee of Shanghai Kedu Healthcare Group,
+Added: the largest medical equipment third-party service provider in China, representing products from GE, Philips, Siemens, Kodak and other
+Added: multi-nationals as well as local companies.
He was appointed to the Board in October 2017.
−Removed: It was his stellar career in the medical field, as well as
−Removed: his significant connections to the investment community throughout Asia, leadership skills and business acumen and experience that caused
−Removed: us to elect him to the Board.
+Added: It was his stellar career in the medical field,
+Added: as well as his significant connections to the investment community throughout Asia, leadership skills and business acumen and experience
+Added: that caused us to elect him to the Board.
Tong has been a Director of Medifocus Inc.
5 unchanged sentences
therapy company focused on providing cell-based treatments for use in veterinary medicine in Asia.
−Removed: Tong’s earlier career includes
−Removed: senior management positions in China with Pfizer and Ball Corporation.
−Removed: He was also responsible for the Healthcare Investment Division
−Removed: of CITIC in Hong Kong.
−Removed: CITIC is the largest conglomerate in China and an established global player,
−Removed: with businesses covering healthcare, financial services, resources, energy, manufacturing, engineering and many others.
+Added: Tong’s earlier career includes senior
+Added: management positions in China with Pfizer and Ball Corporation.
+Added: He was also responsible for the Healthcare Investment Division of CITIC
+Added: in Hong Kong.
+Added: CITIC is the largest conglomerate in China and an established global player, with businesses covering healthcare, financial
+Added: services, resources, energy, manufacturing, engineering and many others.
Tong received his medical degree from the
9 unchanged sentences
several multinational medical and pharmaceutical companies discussed above.
+Added: Matthias Löhr
+Added: Matthias Löhr, MD was appointed to the Board
+Added: in March 2022.
+Added: Löhr is a licensed physician, board-certified internist and Professor of Gastroenterology and Hepatology at the
+Added: Karolinska Institute of Stockholm, Sweden.
+Added: He leads the pancreatic team at Karolinska University Hospital.
+Added: He has served as Professor
+Added: of Molecular Gastroenterology at the University of Heidelberg with a same-named unit at the German Cancer Research Center in Heidelberg
+Added: He has worked as a translational scientist and principal investigator in clinical studies in gastrointestinal oncology for many
+Added: In addition to being highly published, he has extensive scientific and grant review experience, and has received multiple awards
+Added: and distinctions.
+Added: These attributes and his experience in the medical field translate directly to the work being undertaken by us in the
+Added: cancer arena have led us to elect him to the Board.
+Added: Löhr served as the Principal Investigator
+Added: for the Phase 1/2 and Phase 2 clinical trials of the PharmaCyte’s pancreatic cancer therapy that were completed in the early 2000s.
+Added: He is familiar with the Cell-in-a-Box ® live-cell encapsulation technology that forms the core of our pancreatic cancer
+Added: He also administered our therapy for pancreatic cancer in clinical trials in patients with advanced, inoperable pancreatic cancer.
+Added: Löhr has also previously served as a
+Added: consultant to us in connection with our development of treatments for pancreatic cancer and diabetes using the Cell-in-a-Box ®
+Added: He has expertise in both diseases and has a thorough understanding of our technology and its use in a clinical setting.
+Added: Löhr was appointed Professor
+Added: of Molecular Gastroenterology at the University of Heidelberg and became Head of the Division at the German Cancer Research Center, which
+Added: he led until 2010.
+Added: Löhr has authored more than 340 original peer-reviewed scientific papers and more than 50 reviews.
+Added: authored six books.
+Added: He has been granted six patents and is an Editor Board Member of the Journal of Clinical Medicine, Pancreatology,
+Added: Scientific Reports, and the World Journal of Gastroenterology.
+Added: Löhr holds MD and PhD degrees from the
+Added: Universities of Hamburg and Rostock.
+Added: Following receipt of his medical degree, he served a residency in pathology in Hamburg, Germany,
+Added: and residencies in internal medicine and gastroenterology, where he became chief resident and later attending physician and assistant
+Added: professor at the University of Rostock.
Family Relationships
1 unchanged sentence
officers, directors and significant employees.
−Removed: As of April 30, 2021, our personnel do not have any involvement in legal proceedings requiring
−Removed: disclosure pursuant to the Rules and Regulations of the Commission.
−Removed: Corporate Governance and Committees
+Added: Legal Proceedings
+Added: As of April 30, 2022, our personnel do not have
+Added: any involvement in legal proceedings requiring disclosure pursuant to the rules and regulations of the Commission.
+Added: Code of Ethics
Our Board has adopted a written Code of Business
Conduct and Ethics, an Insider Trading Policy and Software Policies that apply to our directors, officers, employees and contractors.
−Removed: These documents can be viewed and downloaded from the “Governance”
−Removed: dropdown menu of our website under the “Company”
+Added: These documents can be viewed and downloaded from the “Governance” dropdown menu of our website under the “Company”
The content of these documents is not incorporated into this Form 10-K.
+Added: Corporate Governance and Committees
Board Leadership and Structure
9 unchanged sentences
Michael Abecassis, Dr.
+Added: Tong, and Mr.
The Chairman of the Audit Committee is Mr.
−Removed: The primary purposes of
−Removed: our Audit Committee are to assist the Board in fulfilling its legal and fiduciary obligations with respect to matters involving the accounting,
+Added: The primary purposes of our Audit
+Added: Committee are to assist the Board in fulfilling its legal and fiduciary obligations with respect to matters involving the accounting,
auditing, financial reporting, internal control, legal compliance and risk management functions of the Company, including, assisting the
−Removed: Board’s oversight of:
+Added: Board’s oversight of:
(i) the integrity of our financial statements;
7 unchanged sentences
Our Board has determined that the Chairman of the Audit Committee,
−Removed: Liquard, is an “audit committee financial expert,”
−Removed: as that term is defined in Item 407(d) of Regulation S-K under the
+Added: Liquard, is an “audit committee financial expert,” as that term is defined in Item 407(d) of Regulation S-K under the
Exchange Act.
Our Audit Committee charter can be viewed and
−Removed: downloaded from the “Governance”
−Removed: dropdown menu of our website under the “Company”
+Added: downloaded from the “Governance” dropdown menu of our website under the “Company” tab.
Compensation Committee
The Compensation Committee is currently comprised
−Removed: Waggoner and Mr.
−Removed: The Chairperson of the Compensation Committee is Mr.
+Added: The Chairperson of the Compensation Committee is Dr.
The primary purposes of our Compensation
5 unchanged sentences
and (iii) to advise the Board with respect to director compensation issues.
−Removed: On July 28, 2021, Mr.
−Removed: Waggoner resigned from the Compensation Committee.
The Compensation Committee, which is composed
−Removed: of a majority of independent directors, provides overall guidance for our executive compensation policies and determines the value and
−Removed: elements of compensation for our executive officers.
+Added: of independent directors, provides overall guidance for our executive compensation policies and determines the value and elements of compensation
+Added: for our executive officers.
Our Compensation Committee charter can be viewed
−Removed: and downloaded from the “Governance”
−Removed: dropdown menu of our website under the “Company”
+Added: and downloaded from the “Governance” dropdown menu of our website under the “Company” tab.
Nominating and Corporate Governance Committee
1 unchanged sentence
is currently comprised of Dr.
−Removed: Crabtree, Dr.
−Removed: The Chairperson of the Nominating and Corporate Governance Committee
−Removed: On July 28, 2021, Dr.
−Removed: Crabtree resigned from the Nominating and Corporate Governances Committee.
+Added: Abecassis and Dr.
+Added: The Chairperson of the Nominating and Corporate Governance Committee is Dr.
The primary purposes of the Nominating Committee
2 unchanged sentences
(iii) to advise the Board
−Removed: with respect to the composition, size and membership of the Board’s committees;
+Added: with respect to the composition, size and membership of the Board’s committees;
(iv) to advise the Board with respect to corporate
3 unchanged sentences
The Nominating Committee also has responsibility for reviewing and approving all transactions that are
−Removed: “related party”
−Removed: transactions under the Commission’s rules.
+Added: “related party” transactions under the Commission’s rules.
The Nominating Committee does not set specific,
31 unchanged sentences
This section discusses the material components
−Removed: of the executive compensation program for our executive officers who are named in the “Summary Compensation Table”
−Removed: a “Named Executive Officer”), as well as the director compensation program for our directors.
+Added: of the executive compensation program for our executive officers who are named in the “Summary Compensation Table” below (each
+Added: a “Named Executive Officer”), as well as the director compensation program for our directors.
As a smaller reporting company,
3 unchanged sentences
Named Executive Officers and their positions were as follows:
−Removed: Waggoner, JD, Chief Executive Officer, President, General Counsel and Chairman of the Board;
−Removed: Crabtree, PhD, Chief Scientific Officer and Director;
−Removed: Trujillo, CPA, Chief Financial Officer and Director.
+Added: Waggoner, Chief Executive Officer, President, General Counsel and Chairman of the Board;
+Added: Crabtree, Chief Scientific Officer and Director;
+Added: Trujillo, Chief Financial Officer and Director.
The following tables provide information about
2 unchanged sentences
Principal Position
−Removed: Waggoner, JD(2)
Chief Executive Officer,
1 unchanged sentence
General Counsel
−Removed: Crabtree, PhD(2)
+Added: Crabtree, (2)
Chief Scientific Officer
−Removed: Trujillo, CPA (2)
Chief Financial Officer
−Removed: amounts in the columns titled “Stock Awards”
−Removed: and “Option Awards”
−Removed: reflect the grant date fair values of awards
−Removed: made during the identified fiscal year, as computed in accordance with FASB ASC Topic 718 and the assumptions stated in Note 4 and Note
−Removed: 5 of the Consolidated Financial Statements to this Report.
+Added: (1) The amounts in the columns titled “Stock
+Added: Awards” and “Option Awards” reflect the grant date fair values of awards made during the identified fiscal year, as
+Added: computed in accordance with FASB ASC Topic 718 and the assumptions stated in Note 4 and Note 5 of the Consolidated Financial Statements
+Added: to this Report.
(2) We did not pay or accrue any other compensation,
3 unchanged sentences
benefits payable to our Named Executive Officers.
−Removed: On October 15, 2018, we adopted a retirement plan for eligible employees named the PharmaCyte
−Removed: Biotech, Inc 401(k) Plan (“Plan”).
−Removed: The Plan allows eligible employees to contribute a portion of their salaries into the Plan.
−Removed: We are not required to and do not contribute to the highly compensated employees accounts and we do not match the contributions of the
−Removed: Named Executive Officers.
Outstanding Equity Awards at Fiscal Year End
7 unchanged sentences
_______________________
−Removed: Subject to the Named Executive Officer’s continued employment, 1/12 th of each grant vests monthly after the grant date.
−Removed: The unexercisable/unvested awards shown in this table were each granted on January 1, 2021.
+Added: Subject to the Named Executive Officer’s continued employment, 1/12 th of each grant vests monthly after the grant date.
+Added: The unexercisable/unvested awards shown in this table were each granted effective as of January 1, 2022.
The market value is based on the closing stock price of $2.33 on April 30, 2022, the last day of trading in this fiscal year.
Employment Arrangements
−Removed: We have entered into an Executive Compensation
−Removed: Agreement with Mr.
−Removed: Waggoner (“Waggoner Compensation Agreement”).
−Removed: The current term of the Waggoner Compensation Agreement extends
−Removed: until December 31, 2021 with annual extensions at the end of the term (or any extension of the term), unless we or Mr.
−Removed: Waggoner provide
−Removed: 90-days written notice of termination.
−Removed: The Waggoner Compensation Agreement provides that Mr.
−Removed: Waggoner will be employed as a member of
−Removed: our Board, as our Chief Executive Officer, President and General Counsel and as the Chief Executive Officer and General Counsel of our
−Removed: subsidiary Viridis Biotech.
+Added: We have entered into an Amended and Restated Executive
+Added: Compensation Agreement with Mr.
+Added: Waggoner (“Waggoner Compensation Agreement”) with an effective date of January 1, 2022.
+Added: current term of the Waggoner Compensation Agreement extends until December 31, 2024, with annual extensions at the end of the term (or
+Added: any extension of the term), unless we or Mr.
+Added: Waggoner provide 90-days written notice of termination.
+Added: The Waggoner Compensation Agreement
+Added: provides that Mr.
+Added: Waggoner will serve as a member of our Board, as our Chief Executive Officer, President and General Counsel and as the
+Added: Chief Executive Officer and General Counsel of our subsidiary Viridis Biotech, Inc.
Under this agreement, Mr.
−Removed: Waggoner is paid a base salary of $375,000 subject to annual increases in the discretion
−Removed: of our Compensation Committee.
−Removed: The Waggoner Compensation Agreement also provides that, during his continued employment, Mr.
−Removed: Waggoner receives
−Removed: an annual stock grant of 2,400 shares of restricted common stock, vesting at the rate of 200 shares per month, and an annual stock option
−Removed: grant to purchase 3,000 shares of common stock exercisable over a five-year term at an exercise price per share equal to the closing price
−Removed: of the common stock on the date of grant, vesting at the rate of 250 option shares per month.
−Removed: Waggoner’s employment is terminated
−Removed: by us without “Cause”
−Removed: or by him for “Good Reason”
−Removed: (as such terms are defined in the Waggoner Compensation Agreement),
+Added: Waggoner is paid a base
+Added: salary of $520,000 subject to annual increases in the discretion of our Compensation Committee and shall be eligible to receive cash incentive
+Added: compensation (“Bonus”).
+Added: Waggoner is eligible to participate in the Company’s 2021 Equity Incentive Plan (“2021
+Added: On May 20, 2022, the Compensation Committee granted Mr.
+Added: Waggoner (i) a stock option grant to purchase 529,000 shares of
+Added: common stock exercisable over a ten-year term at an exercise price per share equal to the closing price of the common stock on the date
+Added: of grant, vesting at the rate of 25% immediately and the remaining vesting monthly over three years from the date of grant, approximately
+Added: 11,000 option shares per month, and (ii) a grant of 150,800 restricted stock units, vesting at the rate of 25% immediately and an additional
+Added: 25% on each anniversary of the grant date.
+Added: Waggoner’s employment is terminated
+Added: by us without “Cause” or by him for “Good Reason” (as such terms are defined in the Waggoner Compensation Agreement),
then subject to his execution of a timely release, he is entitled to:
−Removed: (i) base salary continuation for 2 years, (ii) payment of the
−Removed: annual bonus, if any, earned by Mr.
−Removed: Waggoner for the year preceding the year of termination, or, if greater, the target bonus, if any,
−Removed: for the year of termination, (iii) accelerated vesting of any unvested stock or option awards and (iv) continued health coverage
+Added: (i) severance equal to two times the sum of his base salary at the
+Added: time his employment terminates, (ii) payment of the annual bonus, if any, earned by Mr.
+Added: Waggoner for the year preceding the year of termination,
+Added: or, if greater, the target bonus, if any, for the year of termination, (iii) accelerated vesting of any unvested stock or option awards
+Added: and (iv) continued health coverage for Mr.
Waggoner and his family and life insurance coverage for Mr.
−Removed: Waggoner, if any, for 12 months at the Company’s expense.
+Added: Waggoner, if any, for 18 months
+Added: at the Company’s expense.
Notwithstanding the foregoing, if Mr.
−Removed: Waggoner’s
−Removed: employment is terminated by us without Cause or by him for Good Reason because of a “Change in Control”
−Removed: (as such term is defined
−Removed: in the Waggoner Compensation Agreement), then the base salary and bonus, if any, component of severance would be paid in lump sum.
−Removed: Waggoner would be entitled to receive a full Code Section 280G tax gross-up, with respect to any amounts that may be subject to the
−Removed: excise tax provisions under Code Section 280G.
−Removed: Waggoner’s employment ceases due
+Added: employment is terminated by us without Cause or by him for Good Reason within two years after a “Change in Control” (as such
+Added: term is defined in the Waggoner Compensation Agreement) or within six months prior to a Change in Control, then the base salary and bonus,
+Added: if any, component of severance would be paid in lump sum.
+Added: Waggoner would be entitled to receive a full Code Section 280G tax
+Added: gross-up, with respect to any amounts that may be subject to the excise tax provisions under Code Section 280G.
+Added: Waggoner’s employment ceases due
to his death, (i) any otherwise unvested equity awards held by him at the time of his death would become vested, (ii) his eligible dependents
−Removed: would be entitled to continued healthcare coverage at the Company’s expense for up to 12 months, and (iii) his designated beneficiary
+Added: would be entitled to continued healthcare coverage at the Company’s expense for up to 18 months, and (iii) his designated beneficiary
or estate would receive the proceeds, if any, from any life insurance.
−Removed: Waggoner’s employment is terminated
−Removed: due to “Disability”
−Removed: (as such term is defined in the Waggoner Compensation Agreement) he would receive continued health coverage
+Added: Waggoner’s employment is terminated
+Added: due to “Disability” (as such term is defined in the Waggoner Compensation Agreement) he would receive continued health coverage
and life insurance coverage, if any, for 18 months at our expense, as well as any disability benefits payable under any long-term disability
5 unchanged sentences
and for twenty-four months after termination of his employment.
−Removed: Crabtree, PhD
We have entered into an Executive Compensation
Agreement with Dr.
−Removed: Crabtree (“Crabtree Compensation Agreement”).
+Added: Crabtree (“Crabtree Compensation Agreement”).
The current term of the Crabtree Compensation Agreement extends
3 unchanged sentences
The Crabtree Compensation Agreement provides that Dr.
−Removed: Crabtree will be employed as a member of
−Removed: our Board, as our Chief Scientific Officer and as the Chief Operating Officer of our subsidiary Viridis Biotech.
−Removed: Crabtree is paid
−Removed: a base salary of $84,000 subject to annual increases in the discretion of our Compensation Committee.
−Removed: The Crabtree Compensation Agreement
−Removed: also provides that, during his continued employment, Dr.
−Removed: Crabtree will receive annual stock grants of 400 shares of restricted common
−Removed: stock, vesting at the rate of 33 shares per month, and an annual stock option grant to purchase 1,000 shares of common stock exercisable
−Removed: over a five-year term at an exercise price per share equal to the closing price of the common stock on the date of grant, vesting at the
−Removed: rate of 83 option shares per month.
−Removed: All other terms are substantially the same as
−Removed: disclosed above for the Waggoner Agreement
−Removed: Trujillo, CPA
−Removed: We have entered into an Executive Compensation
−Removed: Agreement with Mr.
−Removed: Trujillo (“Trujillo Compensation Agreement”).
−Removed: The current term of the Trujillo Compensation Agreement extends
−Removed: until December 31, 2021 with annual extensions at the end of the term (or any extension of the term) unless we or Mr.
−Removed: Trujillo provide
−Removed: 90-days written notice of termination.
+Added: Crabtree will serve as a member of our Board,
+Added: as our Chief Scientific Officer and as the Chief Operating Officer of our subsidiary Viridis Biotech.
+Added: Crabtree is paid a base salary
+Added: of $84,000 subject to annual increases in the discretion of our Compensation Committee.
+Added: The Crabtree Compensation Agreement also provides
+Added: that, during his continued employment, Dr.
+Added: Crabtree will receive annual stock grants of 400 shares of restricted common stock, vesting
+Added: at the rate of 33 shares per month, and an annual stock option grant to purchase 1,000 shares of common stock exercisable over a five-year
+Added: term at an exercise price per share equal to the closing price of the common stock on the date of grant, vesting at the rate of 83 option
+Added: shares per month.
+Added: All other terms regarding severance benefits,
+Added: treatment on a change in control, employment termination due to death/disability and restrictive covenants are substantially the same
+Added: as disclosed above for the Waggoner Agreement.
+Added: We have entered into an Amended and Restated Executive
+Added: Compensation Agreement with Mr.
+Added: Trujillo (“Trujillo Compensation Agreement”) with an effective date of January 1, 2022.
+Added: current term of the Trujillo Compensation Agreement extends until December 31, 2024, with annual extensions at the end of the term (or
+Added: any extension of the term) unless we or Mr.
+Added: Trujillo provide 90-days written notice of termination.
The Trujillo Compensation Agreement provides that
−Removed: Trujillo will be employed as a member of our Board, as our Chief Financial Officer and as the Chief Financial Officer of our subsidiary
−Removed: Viridis Biotech.
−Removed: Trujillo is paid an annual base salary of $275,000, subject to annual increases at the discretion of the Compensation
−Removed: The Trujillo Compensation Agreement also provide that during his continued employment, Trujillo will receive annual grants
−Removed: of 1,600 shares of restricted common stock, vesting at the rate of 133 shares per month, and an annual stock option grant to purchase
−Removed: 2,000 shares of common stock exercisable over a five-year term at an exercise price per share equal to the closing price of the common
−Removed: stock on the date of grant, vesting at the rate of 167 option shares per month.
−Removed: All other terms are substantially the same as disclosed above for the
−Removed: Waggoner Agreement.
+Added: Trujillo will serve as a member of our Board and as our Chief Financial Officer.
+Added: Trujillo is paid an annual base salary of $380,000,
+Added: subject to annual increases at the discretion of the Compensation Committee and shall be eligible to receive an annual Bonus.
+Added: is eligible to participate in the 2021 Plan.
+Added: On May 20, 2022, the Compensation Committee granted Mr.
+Added: Trujillo (i) a stock option grant
+Added: to purchase 201,860 shares of common stock exercisable over a ten-year term at an exercise price per share equal to the closing price
+Added: of the common stock on the date of grant, vesting at the rate of 25% immediately and the remaining vesting monthly over three years from
+Added: the date of grant, approximately 4,200 option shares per month, and (ii) a grant of 57,540 restricted stock units, vesting at the rate
+Added: of 25% immediately and an additional 25% on each anniversary of the grant date.
+Added: All other terms regarding severance benefits, treatment on a change
+Added: in control, employment termination due to death/disability and restrictive covenants are substantially the same as disclosed above for
+Added: the Waggoner Agreement.
Directors Compensation
4 unchanged sentences
Thomas C.K Yuen
−Removed: Abecassis, MD
−Removed: T he amounts in the columns titled “Stock Awards”
−Removed: and “Option Awards”
−Removed: reflect the grant date fair values of awards made during the fiscal year ended April 30, 2021, as computed in accordance with FASB ASC Topic 718 and the assumptions stated in Note 4 and Note 5 of the Consolidated Financial Statements to this Report.
−Removed: As of April 30, 2021, each of Mr.
+Added: Matthias Löhr
+Added: The amounts in the columns titled “Stock Awards” and “Option Awards” reflect the grant date fair values of awards made during the fiscal year ended April 30, 2022, as computed in accordance with FASB ASC Topic 718 and the assumptions stated in Note 4 and Note 5 of the Consolidated Financial Statements to this Report.
+Added: As of April 30, 2022, the non-employee directors held unexercised options to purchase shares as follows:
+Added: Liquard, 1,503, Dr.
Abecassis, 2,470 and Dr.
−Removed: Tong held unexercised options to purchase 1,334 shares.
+Added: Tong, 1,670 shares.
These include options granted during the year ended April 30, 2022 (shown in this column) and options granted in prior years.
5 unchanged sentences
(i) 334 shares of our common
−Removed: and (ii) a stock option to purchase 333 shares of our common stock with a term of five years and an exercise price per share
−Removed: equal to the closing price of the common stock on the date of grant.
+Added: and (ii) a stock option to purchase 334 shares of our common stock with a term of five years and an exercise price per share equal
+Added: to the closing price of the common stock on the date of grant.
Each of these equity awards is fully vested upon grant.
2 unchanged sentences
For information regarding the compensation
−Removed: of our three employee directors, please see above, under the heading “Executive Compensation.”
+Added: of our three employee directors, please see above, under the heading “Executive Compensation.”
SECURITY OWNERSHIP OF CERTAIN BENEFICIAL
8 unchanged sentences
Common Stock (1)
−Removed: Waggoner, JD, Chairman of the Board, Chief Executive Officer, President and General Counsel
−Removed: Crabtree, PhD, Chief Scientific Officer and Board Member
−Removed: Trujillo, CPA, Chief Financial Officer and Board Member
+Added: 1,231,482 (2)
+Added: Sabby Volatility Warrant Master Fund, Ltd.
+Added: 1,260,928 (3)
+Added: Iroquois Master Fund Ltd.
+Added: 1,309,099 (4)
+Added: Waggoner, Chairman of the Board, Chief Executive Officer, President and General Counsel
+Added: Crabtree, Chief Scientific Officer and Board Member
+Added: Trujillo, Chief Financial Officer and Board Member
Thomas Liquard, Board Member
−Removed: Yuen, Board Member
−Removed: Abecassis, MD, Board Member
−Removed: Tong, MD, Board Member
+Added: Abecassis, Board Member
+Added: Tong, Board Member
+Added: Matthias Löhr, Board Member
All directors and executive officers as a group (7 persons)
1 unchanged sentence
* Indicates percentage is less than 1.0%.
−Removed: Percentages based on 1,591,750 shares of common stock issued and outstanding as of July 16, 2021, in addition to the options to purchase shares that are unexercised, but which are exercisable within sixty days of July 16, 2021, which are presented as follows:
+Added: Percentages based on 21,601,047 shares of common stock issued and outstanding as of July 15, 2022, in addition to the options to purchase shares that are unexercised, but which are exercisable within sixty days of July 15, 2022, which are presented below:
+Added: This information is based on a Form 13 G/A filed with the SEC on February 11, 2022 by Mitchell P.
+Added: Kopin (“Kopin”).
+Added: Kopin reported sole and shared voting and sole and shared dispositive power of 1,231,482 shares of common stock underlying currently exercisable warrants.
+Added: The address of Kopin is c/o Intracoastal Capital, LLC, 245 Palm Trail, Delray Beach, Florida 33483.
+Added: This information is based on a Form 13 G/A filed with the SEC on January 4, 2022 by Sabby Volatility Warrant Master Fund, Ltd.
+Added: Sabby reported sole and shared voting and sole and shared dispositive power of 1,260,928 shares of common stock underlying currently exercisable warrants.
+Added: The address of Sabby is c/o Ogier Fiduciary Services (Cayman) Limited, 89 Nexus Way, Camana Bay, Grand Cayman KY1-9007, Cayman Islands.
+Added: This information is based on a Form 13 D/A filed with the SEC on July 11, 2022 by Iroquois Master Fund Ltd.
+Added: (“Iroquois”).
+Added: Iroquois reported sole and shared voting and sole and shared dispositive power of 1,309,099 shares of common stock underlying currently exercisable warrants.
+Added: The address of Iroquois is 2 Overhill Road, Suite 400, Scarsdale, New York 10583.
+Added: Includes 529,000 options and 150,800 restricted stock units contingent
+Added: upon stockholder approval.
+Added: Includes 201,860 options and 57,540 restricted stock units contingent
+Added: upon stockholder approval.
+Added: Exercisable options within sixty days of July 15, 2022:
Crabtree, PhD
2 unchanged sentences
Abecassis, MD
−Removed: The address of all beneficial owners is 23046
−Removed: Avenida de la Carlota, Suite 600, Laguna Hills, California 92653.
−Removed: Each person has sole voting and investment power with respect to the
−Removed: shares of common stock.
+Added: Matthias Löhr, MD
+Added: The address of all beneficial owners is 3960 Howard
+Added: Hughes Parkway, Suite 500, Las Vegas, Nevada, 89169.
+Added: Each person has sole voting and investment power with respect to the shares of common
Securities Authorized for Issuance under Equity
28 unchanged sentences
In April 2014, we entered a consulting agreement
−Removed: with Vin-de-Bona pursuant to which it agreed to provide professional consulting services to the Company.
+Added: with Vin-de-Bona pursuant to which it agreed to provide professional consulting services to us.
Vin-de-Bona is owned by Prof.
−Removed: Günzburg and Dr.
−Removed: Salmons, both of whom are involved in numerous aspects of our scientific endeavors relating to cancer and diabetes
−Removed: Gunzburg is the Chairman of Austrianova, and Dr.
+Added: Salmons, both of whom are involved in numerous aspects of our scientific endeavors relating to cancer and diabetes (Prof.
+Added: is the Chairman of Austrianova, and Dr.
Salmons is the Chief Executive Officer and President of Austrianova).
−Removed: of the agreement is for 12 months, automatically renewable for successive 12-month terms.
−Removed: After the initial term, either party can terminate
−Removed: the agreement by giving the other party 30 days’
−Removed: written notice before the effective date of termination.
−Removed: The amounts we paid Vin-de-Bona
−Removed: for the years ended April 30, 2021 and 2020 were approximately $82,000 and $24,000, respectively.
−Removed: In addition, during the years ended
−Removed: April 30, 2021 and 2020 we issued 167 and 167 common shares to Dr.
+Added: The term of the agreement
+Added: is for 12 months, automatically renewable for successive 12-month terms.
+Added: After the initial term, either party can terminate the agreement
+Added: by giving the other party 30 days’ written notice before the effective date of termination.
+Added: The amounts we paid Vin-de-Bona for
+Added: the years ended April 30, 2022, and 2021, were approximately $114,000 and $82,000, respectively.
+Added: In addition, during the years ended April
+Added: 30, 2022, and 2021, we issued 167 and 167 common shares, respectively, to Dr.
We recorded a noncash consulting expense of approximately
1 unchanged sentence
Except for Mr.
−Removed: Tong, the Board has determined that none of our directors satisfy the definition of Independent Director as established in the
−Removed: Nasdaq Marketplace Rules.
−Removed: Abecassis and Dr.
−Removed: Tong have been determined by the Board to be Independent Directors.
+Added: Abecassis, Dr.
+Added: Löhr, the Board has determined that none of our directors satisfy the definition of Independent Director as established in
+Added: the Nasdaq Marketplace Rules.
+Added: Abecassis, Dr.
+Added: Löhr have been determined by the Board to be Independent
PRINCIPAL ACCOUNTANT FEES AND SERVICES
A summary of the fees billed by our independent
−Removed: audit firm, Armanino for professional services rendered for the years ended April 30, 2021 and 2020 is set forth below.
−Removed: Quarterly Review Fees
+Added: audit firm, Armanino LP, for professional services rendered for the years ended April 30, 2022, and 2021 is set forth below.
+Added: Audit-Related Fees
All Other Fees
During the years ended April 30, 2022, and 2021,
−Removed: we paid Armanino $80,196 and $75,121 in annual audit fees, respectively, and $63,590 and $60,106 in quarterly review fees, respectively.
+Added: we incurred from Armanino $167,239 and $80,196 in annual audit fees, respectively, and $33,238 and $63,590 in quarterly review fees, respectively.
+Added: Additional fees relating to capital raises were paid to Armanino in the amounts of $61,149 and $0 during the years ended April 30, 2022,
+Added: and 2021, respectively.
Our Audit Committee pre-approves all services
8 unchanged sentences
Schedule II - Valuation and Qualifying Accounts
−Removed: for the Years Ended 2021 and 2020 are incorporated by reference to page F-27 of the financial statements
−Removed: included herewith.
−Removed: Exhibit 15(a)(2) is being furnished and shall not be deemed to be “filed”
−Removed: for purposes of Section 18 of
−Removed: the Exchange Act or otherwise subject to the liability of that section, nor shall such exhibit be deemed to be incorporated by reference
−Removed: in any registration statement or other document filed under the Securities Act or the Exchange Act, except as otherwise stated in such
+Added: for the Years Ended 2022, and 2021 is incorporated by reference to page F-27 of the financial statements included herewith.
(3) Exhibits.
1 unchanged sentence
the following exhibits are filed as part of, or incorporated by reference into, the Report.
−Removed: Certain of the agreements filed as exhibits contain representations and warranties made by the parties thereto.
−Removed: The assertions embodied in such representations and warranties are not necessarily assertions of fact, but a mechanism for the parties
−Removed: to allocate risk.
−Removed: Accordingly, investors should not rely on the representations and warranties as characterizations of the actual state
−Removed: of facts or for any other purpose at the time they were made or otherwise.
−Removed: Articles of Incorporation
−Removed: of the Company, as amended, dated October 31, 2019
−Removed: Incorporated by reference from
−Removed: the Company’s Quarterly Report on Form 10-Q filed with the SEC on March 13, 2020.
+Added: Certain of the agreements filed as exhibits
+Added: contain representations and warranties made by the parties thereto.
+Added: The assertions embodied in such representations and warranties are
+Added: not necessarily assertions of fact, but a mechanism for the parties to allocate risk.
+Added: Accordingly, investors should not rely on the representations
+Added: and warranties as characterizations of the actual state of facts or for any other purpose at the time they were made or otherwise.
+Added: Articles of Incorporation of the Company, as amended, dated October 31, 2019
+Added: Incorporated by reference from the Company’s Quarterly Report on Form 10-Q filed with the SEC on March 13, 2020.
Corporate Bylaws.
−Removed: Incorporated by reference
−Removed: from the Company’s Registration Statement on Form SB-2 (File No.
+Added: Incorporated by reference from the Company’s Registration Statement on Form SB-2 (File No.
333-68008) filed with the SEC on August 20, 2001.
+Added: Amendment No.
One to the Bylaws of PharmaCyte Biotech, Inc.
−Removed: Incorporated by reference
−Removed: from the Company’s Current Report on Form 8-K filed with the SEC on September 25, 2014.
+Added: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on September 25, 2014.
Amendment No.
−Removed: Bylaws of PharmaCyte Biotech, Inc.
−Removed: Incorporated by reference
−Removed: from the Company’s Current Report on Form 8-K filed with the SEC on October 3, 2014.
+Added: Two to the Bylaws of PharmaCyte Biotech, Inc.
+Added: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on October 3, 2014.
Amendment No.
Three to Bylaws of PharmaCyte Biotech, Inc.
−Removed: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on June 4, 2021.
+Added: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on June 4, 2021.
Amendment No.
Four to Bylaws of PharmaCyte Biotech, Inc.
−Removed: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on July 6, 2021.
+Added: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on July 6, 2021.
Certificate of Amendment to Articles of Incorporation of the Company, dated July 2, 2021
−Removed: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on July 6, 2021.
+Added: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on July 6, 2021.
Certificate of Change to Articles of Incorporation of the Company, dated July 9, 2021
−Removed: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on July 13, 2021
+Added: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on July 13, 2021
Form of Common Stock Certificate.
−Removed: Incorporated by reference
−Removed: from the Company’s Registration Statement on Form SB-2 (File No.
+Added: Incorporated by reference from the Company’s Registration Statement on Form SB-2 (File No.
333-68008) filed with the SEC on August 20, 2001.
1 unchanged sentence
Filed herewith.
−Removed: Subscription Agreement, dated
−Removed: October 30, 2019, between Kenneth L.
−Removed: Waggoner and the Company.
−Removed: Incorporated by reference
−Removed: from the Company’s Quarterly Report on Form 10-Q filed with the SEC on December 23, 2019.
−Removed: Voting Rights Agreement,
−Removed: dated September 16, 2019, among Brown Stone Capital, LP, Silver Rock Associates, Inc., Homie Doroodian and the Company.
−Removed: Incorporated by reference
−Removed: from the Company’s Quarterly Report on Form 10-Q filed with the SEC on December 23, 2019.
−Removed: Share Subscription Agreement,
−Removed: dated January 17, 2020, between Homie Doroodian and the Company.
−Removed: Incorporated by reference
−Removed: from the Company’s Current Report on Form 8-K filed with the SEC on January 21, 2020.
−Removed: Asset Purchase Agreement,
−Removed: dated May 26, 2011, between SG Austria Pte.
+Added: Form of Common Warrant
+Added: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on August 12, 2021.
+Added: Form of Pre-funded Warrant
+Added: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on August 12, 2021.
+Added: Form of Underwriter’s Warrant
+Added: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on August 12, 2021.
+Added: Form of Pre-Funded Common Stock Purchase Warrant
+Added: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on August 23, 2021.
+Added: Form of Series A Warrant Common Stock Purchase Warrant
+Added: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on August 23, 2021.
+Added: Form of Placement Agent Common Stock Purchase Warrant
+Added: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on August 23, 2021.
+Added: Asset Purchase Agreement, dated May 26, 2011, between SG Austria Pte.
and the Company.
−Removed: Incorporated by reference
−Removed: from the Company’s Current Report on Form 8-K filed with the SEC on June 28, 2012.
−Removed: First Addendum, dated June
−Removed: 11, 2011, to Asset Purchase Agreement between SG Austria Pte.
+Added: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on June 28, 2012.
+Added: First Addendum, dated June 11, 2011, to Asset Purchase Agreement between SG Austria Pte.
and the Company.
−Removed: Incorporated by reference
−Removed: from the Company’s Current Report on Form 8-K filed with the SEC on June 28, 2012.
−Removed: Second Addendum, dated June
−Removed: 14, 2012, to Asset Purchase Agreement between SG Austria Pte.
+Added: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on June 28, 2012.
+Added: Second Addendum, dated June 14, 2012, to Asset Purchase Agreement between SG Austria Pte.
and the Company.
−Removed: Incorporated by reference
−Removed: from the Company’s Current Report on Form 8-K filed with the SEC on June 28, 2012.
−Removed: Third Addendum, dated June
−Removed: 25, 2013, to Asset Purchase Agreement between SG Austria Private Limited and the Company.
−Removed: Incorporated by reference
−Removed: from the Company’s Current Report on Form 8-K filed with the SEC on July 18, 2013.
−Removed: Licensing Agreement, dated
−Removed: June 25, 2013, between Austrianova Singapore Pte.
+Added: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on June 28, 2012.
+Added: Third Addendum, dated June 25, 2013, to Asset Purchase Agreement between SG Austria Private Limited and the Company.
+Added: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on July 18, 2013.
+Added: Licensing Agreement, dated June 25, 2013, between Austrianova Singapore Pte.
and the Company.
−Removed: Incorporated by reference
−Removed: from the Company’s Current Report on Form 8-K filed with the SEC on July 18, 2013.
−Removed: Manufacturing Framework Agreement,
−Removed: dated March 20, 2014, between Austrianova Singapore Pte.
+Added: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on July 18, 2013.
+Added: Manufacturing Framework Agreement, dated March 20, 2014, between Austrianova Singapore Pte.
and the Company.
−Removed: Incorporated by reference
−Removed: from the Company’s Annual Report on Form 10-K filed with the SEC on August 4, 2014.
−Removed: Master Services Agreement,
−Removed: dated April 7, 2014, between ViruSure GmbH and the Company.
−Removed: Incorporated by reference
−Removed: from the Company’s Annual Report on Form 10-K filed with the SEC on August 4, 2014.
−Removed: Consulting Agreement, dated
−Removed: April 1, 2014, between Vin-de-Bona Trading Company Pte.
+Added: Incorporated by reference from the Company’s Annual Report on Form 10-K filed with the SEC on August 4, 2014.
+Added: Master Services Agreement, dated April 7, 2014, between ViruSure GmbH and the Company.
+Added: Incorporated by reference from the Company’s Annual Report on Form 10-K filed with the SEC on August 4, 2014.
+Added: Consulting Agreement, dated April 1, 2014, between Vin-de-Bona Trading Company Pte.
and the Company.
−Removed: Incorporated by reference
−Removed: from the Company’s Annual Report on Form 10-K filed with the SEC on August 4, 2014.
−Removed: License Agreement, dated
−Removed: October 13, 2014, between University of Technology, Sydney and PharmaCyte Biotech Australia Pty Ltd (formerly, Nuvilex Australia
−Removed: Incorporated by reference
−Removed: from Amendment No.
−Removed: 1 to the Company’s Annual Report on Form 10-K/A filed with the SEC on October 17, 2014.
−Removed: Master Services Agreement,
−Removed: dated March 7, 2014, between ViruSure GmbH and the Company.
−Removed: Incorporated by reference
−Removed: from Amendment No.
−Removed: 1 to the Company’s Annual Report on Form 10-K/A filed with the SEC on October 17, 2014.
−Removed: Licensing Agreement, dated
−Removed: December 1, 2014, between Austrianova Singapore Pte.
+Added: Incorporated by reference from the Company’s Annual Report on Form 10-K filed with the SEC on August 4, 2014.
+Added: License Agreement, dated October 13, 2014, between University of Technology, Sydney and PharmaCyte Biotech Australia Pty Ltd (formerly, Nuvilex Australia Pty Ltd).
+Added: Incorporated by reference from Amendment No.
+Added: 1 to the Company’s Annual Report on Form 10-K/A filed with the SEC on October 17, 2014.
+Added: Master Services Agreement, dated March 7, 2014, between ViruSure GmbH and the Company.
+Added: Incorporated by reference from Amendment No.
+Added: 1 to the Company’s Annual Report on Form 10-K/A filed with the SEC on October 17, 2014.
+Added: Licensing Agreement, dated December 1, 2014, between Austrianova Singapore Pte.
and the Company.
−Removed: Incorporated by reference
−Removed: to the Company’s Quarterly Report on Form 10-Q filed with the SEC on December 15, 2014.
−Removed: 10.12†
−Removed: Executive Compensation Agreement,
−Removed: dated March 10, 2015, between Kenneth L.
−Removed: Waggoner and the Company.
−Removed: Incorporated by reference
−Removed: from the Company’s Quarterly Report on Form 10-Q filed with the SEC on March 13, 2015.
−Removed: 10.13†
−Removed: First Stock Option Agreement,
−Removed: dated March 10, 2015, between Kenneth L.
+Added: Incorporated by reference to the Company’s Quarterly Report on Form 10-Q filed with the SEC on December 15, 2014.
+Added: First Stock Option Agreement, dated March 10, 2015, between Kenneth L.
Waggoner and the Company.
−Removed: Incorporated by reference
−Removed: from the Company’s Quarterly Report on Form 10-Q filed with the SEC on March 13, 2015.
−Removed: 10.14†
−Removed: Second Stock Option Agreement,
−Removed: dated March 10, 2015, between Kenneth L.
+Added: Incorporated by reference from the Company’s Quarterly Report on Form 10-Q filed with the SEC on March 13, 2015.
+Added: Second Stock Option Agreement, dated March 10, 2015, between Kenneth L.
Waggoner and the Company.
−Removed: Incorporated by reference
−Removed: from the Company’s Quarterly Report on Form 10-Q filed with the SEC on March 13, 2015.
−Removed: 10.15†
−Removed: Executive Compensation Agreement,
−Removed: dated January 1, 2015, between Gerald W.
+Added: Incorporated by reference from the Company’s Quarterly Report on Form 10-Q filed with the SEC on March 13, 2015.
+Added: Executive Compensation Agreement, dated January 1, 2015, between Gerald W.
Crabtree and the Company.
−Removed: Incorporated by reference
−Removed: from the Company’s Quarterly Report on Form 10-Q filed with the SEC on March 13, 2015.
−Removed: 10.16†
−Removed: First Stock Option Agreement,
−Removed: dated March 10, 2015, between Gerald W.
+Added: Incorporated by reference from the Company’s Quarterly Report on Form 10-Q filed with the SEC on March 13, 2015.
+Added: First Stock Option Agreement, dated March 10, 2015, between Gerald W.
Crabtree and the Company.
−Removed: Incorporated by reference
−Removed: from the Company’s Quarterly Report on Form 10-Q filed with the SEC on March 13, 2015.
−Removed: 10.17†
−Removed: Second Stock Option Agreement,
−Removed: dated March 10, 2015, between Gerald W.
+Added: Incorporated by reference from the Company’s Quarterly Report on Form 10-Q filed with the SEC on March 13, 2015.
+Added: Second Stock Option Agreement, dated March 10, 2015, between Gerald W.
Crabtree and the Company.
−Removed: Incorporated by reference
−Removed: from the Company’s Quarterly Report on Form 10-Q filed with the SEC on March 13, 2015.
−Removed: 10.18†
−Removed: Letter agreement, dated April
−Removed: 20, 2015, between Thomas Liquard and the Company.
−Removed: Incorporated by reference
−Removed: from the Company’s Current Report on Form 8-K filed with the SEC on April 29, 2015.
−Removed: 10.19†
+Added: Incorporated by reference from the Company’s Quarterly Report on Form 10-Q filed with the SEC on March 13, 2015.
+Added: Letter agreement, dated April 20, 2015, between Thomas Liquard and the Company.
+Added: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on April 29, 2015.
Amendment No.
1 unchanged sentence
Crabtree and the Company.
−Removed: Incorporated by reference from the Company’s Quarterly Report on Form 10-Q filed with the SEC on March 8, 2016.
−Removed: 10.20†
−Removed: Amendment No.
−Removed: 1, December 30, 2015, to Executive Compensation Agreement between Kenneth L.
−Removed: Waggoner and the Company.
−Removed: Incorporated by reference from the Company’s Quarterly Report on Form 10-Q filed with the SEC on March 8, 2016.
−Removed: 10.21†
+Added: Incorporated by reference from the Company’s Quarterly Report on Form 10-Q filed with the SEC on March 8, 2016.
Third Stock Option Agreement, dated December 30, 2015, between Gerald W.
Crabtree and the Company.
−Removed: Incorporated by reference from the Company’s Quarterly Report on Form 10-Q filed with the SEC on March 8, 2016.
−Removed: 10.22†
+Added: Incorporated by reference from the Company’s Quarterly Report on Form 10-Q filed with the SEC on March 8, 2016.
Third Stock Option Agreement, dated December 30, 2015, between Kenneth L.
Waggoner and the Company.
−Removed: Incorporated by reference from the Company’s Quarterly Report on Form 10-Q filed with the SEC on March 8, 2016.
+Added: Incorporated by reference from the Company’s Quarterly Report on Form 10-Q filed with the SEC on March 8, 2016.
First Amendment, dated June 30, 2015, to Licensing Agreement, dated December 1, 2014, between Austrianova Singapore Pte.
and the Company.
−Removed: Incorporated by reference from the Company’s Annual Report on Form 10-K filed with the SEC on July 29, 2016.
+Added: Incorporated by reference from the Company’s Annual Report on Form 10-K filed with the SEC on July 29, 2016.
Second Amendment, dated October 19, 2015, to Licensing Agreement, dated December 1, 2014, between Austrianova Singapore Pte.
and the Company .
−Removed: Incorporated by reference from the Company’s Annual Report on Form 10-K filed with the SEC on July 29, 2016.
+Added: Incorporated by reference from the Company’s Annual Report on Form 10-K filed with the SEC on July 29, 2016.
Variation, dated April 20, 2016, to License Agreement, October 13, 2014, between University of Technology, Sydney and PharmaCyte Biotech Australia Pty Ltd (formerly, Nuvilex Australia Pty Ltd).
−Removed: Incorporated by reference from the Company’s Annual Report on Form 10-K filed with the SEC on July 29, 2016.
+Added: Incorporated by reference from the Company’s Annual Report on Form 10-K filed with the SEC on July 29, 2016.
First Amendment, dated June 24, 2016, to Licensing Agreement, dated June 25, 2013, between Austrianova Singapore Pte.
and the Company.
−Removed: Incorporated by reference from the Company’s Annual Report on Form 10-K filed with the SEC on July 29, 2016.
+Added: Incorporated by reference from the Company’s Annual Report on Form 10-K filed with the SEC on July 29, 2016.
Binding Memorandum of Understanding, dated July 28, 2016, between Austrianova Singapore Pte Ltd.
and the Company.
−Removed: Incorporated by reference from the Company’s Annual Report on Form 10-K filed with the SEC on July 29, 2016.
−Removed: 10.28†
−Removed: Amendment No.
−Removed: 2, dated March 10, 2017, to Executive Compensation Agreement between Kenneth L.
−Removed: Waggoner and the Company.
−Removed: Incorporated by reference from the Company’s Quarterly Report on Form 10-Q filed with the SEC on March 13, 2017.
−Removed: 10.30†
−Removed: Amendment No.
−Removed: 2, dated March 10, 2017, to Executive Compensation Agreement between Carlos A.
−Removed: Trujillo and the Company.
−Removed: Incorporated by reference from the Company’s Quarterly Report on Form 10-Q filed with the SEC on March 13, 2017.
−Removed: 10.31†
+Added: Incorporated by reference from the Company’s Annual Report on Form 10-K filed with the SEC on July 29, 2016.
Amendment No.
1 unchanged sentence
Crabtree and the Company.
−Removed: Incorporated by reference from the Company’s Quarterly Report on Form 10-Q filed with the SEC on March 13, 2017.
−Removed: 10.32†
+Added: Incorporated by reference from the Company’s Quarterly Report on Form 10-Q filed with the SEC on March 13, 2017.
Fourth Stock Option Agreement, dated March 10, 2017, between Kenneth L.
Waggoner and the Company.
−Removed: Incorporated by reference from the Company’s Quarterly Report on Form 10-Q filed with the SEC on March 13, 2017.
−Removed: 10.33†
+Added: Incorporated by reference from the Company’s Quarterly Report on Form 10-Q filed with the SEC on March 13, 2017.
Third Stock Option Agreement, dated March 10, 2017, between Carlos A.
Trujillo and the Company.
−Removed: Incorporated by reference from the Company’s Quarterly Report on Form 10-Q filed with the SEC on March 13, 2017.
−Removed: 10.34†
+Added: Incorporated by reference from the Company’s Quarterly Report on Form 10-Q filed with the SEC on March 13, 2017.
Fourth Stock Option Agreement, dated March 10, 2017, between Gerald W.
Crabtree and the Company.
−Removed: Incorporated by reference from the Company’s Quarterly Report on Form 10-Q filed with the SEC on March 13, 2017.
−Removed: 10.35†
+Added: Incorporated by reference from the Company’s Quarterly Report on Form 10-Q filed with the SEC on March 13, 2017.
Amendment No.
1, dated March 10, 2017, to Letter Agreement between Thomas Liquard and the Company.
−Removed: Incorporated by reference from the Company’s Quarterly Report on Form 10-Q filed with the SEC on March 13, 2017.
−Removed: 10.36†
+Added: Incorporated by reference from the Company’s Quarterly Report on Form 10-Q filed with the SEC on March 13, 2017.
Letter Agreement, dated May 1, 2017, between Thomas C.
Yuen and the Company.
−Removed: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on May 2, 2017.
−Removed: 10.37†
+Added: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on May 2, 2017.
Letter agreement, dated June 29, 2017, between Michael Abecassis, M.D.
and the Company.
−Removed: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on July 10, 2017.
+Added: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on July 10, 2017.
Binding Term Sheet, dated August 30, 2017, among Austrianova Singapore Pte.
1 unchanged sentence
and the Company.
−Removed: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on September 6, 2017.
−Removed: 10.39†
+Added: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on September 6, 2017.
Letter agreement, dated October 9, 2017, between Raymond C.
Tong and the Company.
−Removed: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on October 10, 2017.
+Added: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on October 10, 2017.
Fourth Addendum, dated May 14, 2018, to Asset Purchase Agreement between SG Austria Pte.
and the Company.
−Removed: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on May 15, 2018.
+Added: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on May 15, 2018.
Third Amendment, dated May 14, 2018, to Licensing Agreement, dated December 1, 2014, between Austrianova Singapore Pte.
Ltd and the Company.
−Removed: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on May 15, 2018.
+Added: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on May 15, 2018.
Second Amendment, dated May 14, 2018, to the Licensing Agreement, dated June 25, 2013, between Austrianova Singapore Pte.
Ltd and the Company.
−Removed: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on May 15, 2018.
−Removed: 10.43†
+Added: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on May 15, 2018.
Amendment No.
1 unchanged sentence
Crabtree and the Company.
−Removed: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on October 16, 2020.
+Added: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on October 16, 2020.
+Added: Securities Purchase Agreement, dated as of August 19, 2021.
+Added: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on August 23, 2021.
+Added: Amended and Restated Executive Compensation Agreement, dated May 8, 2022, between Kenneth L.
+Added: Waggoner and the Company.
+Added: Filed herewith.
+Added: Amended and Restated Executive Compensation Agreement, dated May 8, 2022, between Carlos A.
+Added: Trujillo and the Company.
+Added: Filed herewith.
PharmaCyte Biotech, Inc.
+Added: 2021 Equity Incentive Plan.
+Added: Filed herewith.
+Added: PharmaCyte Biotech, Inc.
Code of Business Conduct and Ethics.
−Removed: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on September 25, 2014.
−Removed: Schedule II - Valuation and Qualifying Accounts for the Years Ended April 30, 2021 and 2020.
−Removed: Incorporated by reference to page F-27 of the financial statements included herewith.
+Added: Incorporated by reference from the Company’s Current Report on Form 8-K filed with the SEC on September 25, 2014.
List of Subsidiaries.
12 unchanged sentences
Furnished herewith.
−Removed: Interactive Data Files for PharmaCyte Biotech, Inc.
−Removed: Form 10-K for the period ended April 30, 2021.
−Removed: Submitted herewith.
+Added: Inline XBRL Instance Document - the instance document does not appear in the Interactive Data File because its XBRL tags are embedded within the Inline XBRL document.
+Added: Filed herewith.
+Added: Inline XBRL Taxonomy Extension Schema Document
+Added: Filed herewith.
+Added: Inline XBRL Taxonomy Extension Calculation Linkbase Document
+Added: Filed herewith.
+Added: Inline XBRL Taxonomy Extension Definition Linkbase Document
+Added: Filed herewith.
+Added: Inline XBRL Taxonomy Extension Label Linkbase Document
+Added: Filed herewith.
+Added: Inline XBRL Taxonomy Extension Presentation Linkbase Document
+Added: Filed herewith.
+Added: Cover Page Interactive Data File (formatted as Inline XBRL and contained in Exhibits 101)
+Added: Filed herewith.
† A contract, compensatory plan or arrangement
3 unchanged sentences
set forth on page F-27 of this Report:
−Removed: Schedule II —
+Added: Schedule II — Valuation
and Qualifying Accounts for the years ended April 30, 2022, and 2021.
5 unchanged sentences
PharmaCyte Biotech, Inc.
−Removed: August 9, 2021
+Added: July 28, 2022
/s/ Kenneth L.
1 unchanged sentence
(Duly Authorized Officer and Principal Executive Officer)
−Removed: August 9, 2021
+Added: July 28, 2022
/s/ Carlos A Trujillo
−Removed: Chief Financial Officer (Duly Authorized Officer and Principal Financial
+Added: Chief Financial Officer
+Added: (Duly Authorized Officer and Principal Financial
and Accounting Officer)
1 unchanged sentence
this Report has been signed below by the following persons on behalf of the registrant and in the capacities and on the dates indicated.
−Removed: August 9, 2021
+Added: July 28, 2022
/s/ Kenneth L.
−Removed: Chief Executive Officer, Chairman of the Board
+Added: Chief Executive Officer, Chairman of the Board and Director
(Principal Executive Officer)
−Removed: August 9, 2021
+Added: July 28, 2022
/s/ Carlos A.
Chief Financial Officer and Director
−Removed: (Principal Financial and Accounting Officer)
−Removed: August 9, 2021
+Added: (Principal Financial and Accounting
+Added: July 28, 2022
/s/ Gerald W.
Crabtree, Director
−Removed: August 9, 2021
+Added: July 28, 2022
/s/ Thomas Liquard
Thomas Liquard, Director
−Removed: August 9, 2021
−Removed: /s/ Thomas C.K.
−Removed: Yuen, Director
−Removed: August 9, 2021
−Removed: /s/ Raymond C.F.
−Removed: Tong, Director
−Removed: August 9, 2021
+Added: July 28, 2022
/s/ Michael M.
Abecassis, Director
+Added: July 28, 2022
+Added: /s/ Raymond C.F.
+Added: Tong, Director
+Added: July 28, 2022
+Added: /s/ Matthias Löhr
+Added: Matthias Löhr, Director
SUPPLEMENTAL INFORMATION TO BE FURNISHED WITH
2 unchanged sentences
The registrant has not sent to its security holders any annual report
−Removed: covering the registrant’s fiscal year ended April 30, 2021.
+Added: covering the registrant’s fiscal year ended April 30, 2022.
PHARMACYTE BIOTECH, INC.
−Removed: FINANCIAL STATEMENTS AND SUPPLEMENTARY
−Removed: Report of Independent Registered Public Accounting Firm
+Added: FINANCIAL STATEMENTS AND SUPPLEMENTARY DATA
+Added: Independent Registered Public Accounting Firm (PCAOB Auditor ID:
Consolidated Balance Sheets as of April 30, 2022, and 2021
1 unchanged sentence
Consolidated Statements of Comprehensive Loss for the Years Ended April 30, 2022, and 2021
−Removed: Consolidated Statements of Stockholders’
−Removed: Equity for the Years Ended April 30, 2021 and 2020
+Added: Consolidated Statements of Stockholders’ Equity for the Years Ended April 30, 2022, and 2021
Consolidated Statements of Cash Flows for the Years Ended April 30, 2022, and 2021
1 unchanged sentence
Financial Statement Schedule II - Valuation and Qualifying Accounts
−Removed: REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING
−Removed: The Board of Directors
−Removed: Stockholders of PharmaCyte
−Removed: Biotech, Inc.
−Removed: Laguna Hills, California
+Added: REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
+Added: To the Board of Directors
+Added: and Stockholders
+Added: PharmaCyte Biotech, Inc.
+Added: Las Vegas, Nevada
Opinion on the
2 unchanged sentences
consolidated balance sheets of PharmaCyte Biotech, Inc.
−Removed: and subsidiaries (collectively the "Company") as of April 30, 2021 and
+Added: and subsidiaries (collectively the "Company") as of April 30, 2022 and
2021, and the related consolidated statements of operations, comprehensive loss, stockholders' equity, and cash flows for each of the
8 unchanged sentences
with the related consolidated financial statements.
−Removed: Basis for Opinions
+Added: Basis for Opinion
The Company's management
23 unchanged sentences
We believe that our audits provide a reasonable basis for our opinion.
−Removed: Critical Audit Matter
−Removed: The critical audit matter communicated below arises
−Removed: from the current period audit of the consolidated financial statements that were communicated or required to be communicated to the audit
−Removed: committee and that:
−Removed: (1) relate to accounts or disclosures that are material to the consolidated financial statements and (2) involved
−Removed: our especially challenging, subjective, or complex judgments.
−Removed: The communication of the critical audit matter does not alter in any way
−Removed: our opinion on the consolidated financial statements, taken as a whole, and we are not, by communicating the critical audit matter below,
−Removed: providing separate opinions on the critical audit matter or on the accounts or disclosures to which it relates.
−Removed: Going Concern —
−Removed: Refer to Note 2 to the
−Removed: Consolidated Financial Statements
−Removed: Critical Audit Matter Description
−Removed: As disclosed in the consolidated financial statements,
−Removed: the Company prepared the consolidated financial statements assuming that the Company will continue as a going concern and conditions raise
−Removed: substantial doubt about the Company’s ability to do so.
−Removed: Since inception, the Company has a significant accumulated deficit and has
−Removed: experienced significant losses and incurred negative cash flows from operations.
−Removed: The Company requires substantial additional capital to
−Removed: finance its planned business operations and expects to continue incurring operating losses for the foreseeable future.
−Removed: Management determined
−Removed: that its plans to raise capital alleviate substantial doubt about the Company’s ability to continue as a going concern.
−Removed: We identified the evaluation of going concern
−Removed: as a critical audit matter due to significant judgment exercised by the Company in (a) preparing its forecast of cash expenditures to
−Removed: support the Company’s drug research and development, (b) determining whether management’s plans alleviate substantial doubt,
−Removed: and (c) providing complete and accurate disclosures related to the Company’s assessment of going concern.
−Removed: Given these factors, the related audit effort
−Removed: in evaluating management’s judgments was extensive and required a high degree of auditor judgment.
−Removed: How the Critical Audit Matter Was Addressed in the Audit
−Removed: Our principal audit procedures related to this critical audit matter included the following:
−Removed: We tested the completeness and accuracy of underlying data used in the forecast
−Removed: of expenditures including consideration of current and past expenditures in evaluating the forecasted fixed and variable costs.
−Removed: We assessed management’s key assumptions and reasonableness in forecasting
−Removed: cash expenditures by performing a retrospective review of historical forecasts and comparing information related to the Company’s
−Removed: anticipated clinical trials to management’s assumptions.
−Removed: We evaluated assumptions used by the Company in determining whether management’s
−Removed: plans alleviate substantial doubt by assessing the likelihood the Company will raise funds from a public stock offering and other sources.
−Removed: We evaluated the adequacy of management’s disclosure in the consolidated
−Removed: financial statements regarding going concern by comparing to other audit evidence obtained to determine whether such information is consistent
−Removed: with the Company’s going concern disclosure.
+Added: Critical Audit Matters
+Added: Critical audit matters are matters arising from
+Added: the current period audit of the consolidated financial statements that were communicated or required to be communicated to the audit committee
+Added: that (1) relate to accounts or disclosures that are material to the consolidated financial statements and (2) involved our especially
+Added: challenging, subjective or complex judgments.
+Added: We determined that there were no critical audit matters.
/s/ Armanino LLP
−Removed: San Jose, California
−Removed: August 9, 2021
+Added: Bellevue, Washington
+Added: July 28, 2022
We have served as the
3 unchanged sentences
Current assets:
+Added: Cash and cash equivalents
Prepaid expenses and other current assets
8 unchanged sentences
Accrued expenses
−Removed: Current portion of Small Business Administration –
−Removed: Paycheck Protection Program loan
Total current liabilities
−Removed: Long-term liabilities, less current portion:
−Removed: Small Business Administration –
−Removed: Paycheck Protection Program loan
Total Liabilities
24 unchanged sentences
Loss from operations
+Added: ( 4,392,014 )
+Added: ( 3,622,981 )
Other income (expense):
−Removed: Gain on forgiveness of Paycheck
−Removed: Protection Program loan
+Added: Gain on forgiveness of Paycheck Protection Program loan
+Added: Interest income
Interest expense
−Removed: Other income (expense), net
−Removed: Total other income (expense), net
+Added: Other expense, net
+Added: Total other income, net
$ ( 4,239,161 )
$ ( 3,551,236 )
−Removed: Basic and diluted loss per share
−Removed: Weighted average shares outstanding basic and diluted
+Added: Basic loss per share
+Added: Diluted loss per share
+Added: Weighted average shares outstanding basic
+Added: Weighted average shares outstanding diluted
The accompanying notes are an integral part
5 unchanged sentences
$ ( 3,551,236 )
−Removed: Other comprehensive loss:
+Added: Other comprehensive income:
Foreign currency translation adjustments
−Removed: Other comprehensive income (loss)
+Added: Other comprehensive income
Comprehensive loss
6 unchanged sentences
YEARS ENDED APRIL 30, 2022, AND 2021
+Added: Additional Paid-in
Comprehensive
−Removed: Stockholders’
+Added: Stockholders’
Balance, April 30, 2020
1 unchanged sentence
$ ( 103,858,259 )
−Removed: Shares issued for compensation
−Removed: Shares issued for services
−Removed: Shares issued for cash, net of issuance costs of $202,000
+Added: Stock issued for compensation
+Added: Stock issued for services
+Added: Stock issued for cash, net of issuance
+Added: costs of $ 472,300
+Added: Stock issued for warrant exercises
Stock-based compensation - options
−Removed: Foreign currency translation adjustment
+Added: Foreign currency translation adjustments
+Added: ( 3,551,236 )
Balance, April 30, 2021
$ 114,109,169
−Removed: Shares issued for compensation
−Removed: Shares issued for services
−Removed: Shares issued for cash, net of issuance costs of $472,300
−Removed: Shares issued for warrant exercises
+Added: $ ( 107,409,495 )
+Added: Stock issued for compensation
+Added: Stock issued for services
+Added: Stock issued for cash, net of cash
+Added: issuance costs of $ 8,362,137
Stock-based compensation - options
+Added: Issuance of pre-funded warrants
+Added: Reverse stock split adjustment
Foreign currency translation adjustments
+Added: ( 4,239,161 )
+Added: ( 4,239,161 )
Balance, April 30, 2022
16 unchanged sentences
Increase (decrease) in prepaid expenses and other current assets
+Added: Decrease in other assets
Increase (decrease) in accounts payable
−Removed: Increase (decrease) in accrued expenses
+Added: Decrease in accrued expenses
Net cash used in operating activities
+Added: ( 4,117,319 )
+Added: ( 3,330,889 )
Cash flows from investing activities:
1 unchanged sentence
Cash flows from financing activities:
−Removed: Proceeds from sale of Series A Preferred stock
−Removed: Repurchase of Series A Preferred stock
−Removed: Use of funds for payment of insurance financing loan
−Removed: Proceeds from Small Business Administration –
−Removed: Paycheck Protection Program
+Added: Payment of insurance financing loan
Proceeds from sale of common stock, net of issuance costs
Net cash provided by financing activities
−Removed: Effect of currency rate exchange on cash
−Removed: Net increase in cash
−Removed: Cash at beginning of the year
−Removed: Cash at end of the year
+Added: Effect of currency rate exchange on cash and cash equivalents
+Added: Net increase in cash and cash equivalents
+Added: Cash and cash equivalents at beginning of the year
+Added: Cash and cash equivalents at end of the year
Supplemental disclosure of cash flows information:
−Removed: Cash paid during the year for
−Removed: Cash paid during the year for interest expense
+Added: Cash paid during the years for income taxes
+Added: Cash paid during the years for interest expense
+Added: Non-cash equity issuance costs
The accompanying notes are an integral part
2 unchanged sentences
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
−Removed: NOTE 1 –
−Removed: NATURE OF BUSINESS
+Added: NOTE 1 – NATURE OF BUSINESS
PharmaCyte Biotech, Inc.
−Removed: (“Company”)
−Removed: is a biotechnology company focused on developing cellular therapies for cancer and diabetes based upon a proprietary cellulose-based live
−Removed: cell encapsulation technology known as “Cell-in-a-Box ®
−Removed: The Cell-in-a-Box ®
−Removed: technology is intended
−Removed: to be used as a platform upon which therapies for several types of cancer, including locally advanced, inoperable, pancreatic cancer (“LAPC”),
−Removed: and Type 1 and insulin dependent Type 2 diabetes will be developed.
+Added: is a biotechnology company focused on developing cellular therapies for cancer, diabetes and malignant ascites based upon a proprietary
+Added: cellulose-based live cell encapsulation technology known as “Cell-in-a-Box ® .” The Cell-in-a-Box ®
+Added: technology is intended to be used as a platform upon which therapies for several types of cancer, including locally advanced, inoperable
+Added: pancreatic cancer (“LAPC”) will be developed.
+Added: The current generation of the Company’s product candidate is referred
+Added: to as “CypCaps™.”
+Added: On September 1, 2020, the Company submitted an
+Added: Investigational New Drug Application (“IND”) to the United States Food and Drug Administration (“FDA”) for a planned
+Added: Phase 2b clinical trial in LAPC.
+Added: On October 1, 2020, the Company received notice from the FDA that it had placed the IND on clinical hold.
+Added: On October 30, 2020, the FDA sent a letter to the Company setting forth the reasons for the clinical hold and specific guidance on what
+Added: the Company must do to have the clinical hold lifted.
+Added: To lift the clinical hold, the FDA has informed
+Added: the Company that it needs to conduct several additional preclinical studies.
+Added: The FDA also requested additional information regarding several
+Added: topics, including DNA sequencing data, manufacturing information and product release specifications.
+Added: The Company is also in the process
+Added: of conducting these studies and gathering additional information to submit to the FDA.
+Added: See “Clinical Hold” below.
+Added: The Cell-in-a-Box ® encapsulation
+Added: technology potentially enables genetically engineered live human cells to be used as a means to produce various biologically active molecules.
+Added: The technology is intended to result in the formation of pinhead sized cellulose-based porous capsules in which genetically modified live
+Added: human cells can be encapsulated and maintained.
+Added: In a laboratory setting, this proprietary live cell encapsulation technology has been
+Added: shown to create a micro-environment in which encapsulated cells survive and flourish.
+Added: They are protected from environmental challenges,
+Added: such as the sheer forces associated with bioreactors and passage through catheters and needles.
+Added: The Company believes that this enables
+Added: greater cell growth and production of the active molecules.
+Added: The capsules are largely composed of cellulose (cotton) and are bioinert.
The Company is developing therapies for pancreatic
and other solid cancerous tumors by using genetically engineered live human cells that it believes are capable of converting a cancer
−Removed: prodrug into its cancer-killing form, encapsulating those cells using the Cell-in-a-Box ®
−Removed: technology and placing those capsules
−Removed: in the body as close as possible to the tumor.
−Removed: The Company believes that when the cancer prodrug is administered to a patient with a particular
−Removed: type of cancer that may be affected by the prodrug, the killing of the patient’s tumor may be optimized.
−Removed: The Company is also examining ways to exploit
−Removed: the benefits of the Cell-in-a-Box ®
−Removed: technology to develop therapies for cancer that involve prodrugs based upon certain
−Removed: constituents of the Cannabis plant;
−Removed: these constituents are of the class of compounds known as “cannabinoids”.
−Removed: (i) the FDA allows the Company to commence a clinical trial in LAPC described in the IND upon which the FDA has placed a clinical hold,
−Removed: (ii) the Company validates the Cell-in-a-Box ®
−Removed: encapsulation technology in our planned Phase 2b clinical trial in LAPC and
−Removed: (iii) the availability of sufficient additional funding, the Company will not be spending any further resources developing this program.
−Removed: In addition, the Company is developing a therapy
−Removed: to delay the production and accumulation of malignant ascites fluid that results from many types of abdominal cancerous tumors.
−Removed: ascites fluid is secreted by abdominal cancerous tumors into the abdomen after the tumors have reached a certain stage of growth.
−Removed: fluid contains cancer cells that can seed and form new tumors throughout the abdomen.
−Removed: This fluid accumulates in the abdominal cavity,
−Removed: causing swelling of the abdomen, severe breathing difficulties and extreme pain.
−Removed: The Company is using its therapy for pancreatic
−Removed: cancer to determine if it can prevent or delay the production and accumulation of malignant ascites fluid.
−Removed: As with the Company’s
−Removed: Cannabis program, until (i) the FDA allows the Company to commence a clinical trial in LAPC described in the IND upon which the
−Removed: FDA has placed a clinical hold, (ii) the Company validates the Cell-in-a-Box ®
−Removed: encapsulation technology in our planned Phase
−Removed: 2b clinical trial in LAPC and (iii) the availability of sufficient additional funding, the Company will not be spending any further resources
−Removed: developing this program.
−Removed: The Company is also developing a therapy for Type
−Removed: 1 diabetes and insulin-dependent Type 2 diabetes.
−Removed: The Company’s diabetes therapy consists of encapsulated genetically modified insulin-producing
−Removed: The encapsulation will be done using the Cell-in-a-Box ®
−Removed: Implanting these cells in the body is designed
−Removed: to function as a bio-artificial pancreas for purposes of insulin production.
−Removed: As with the two previous programs, the Company is not spending
−Removed: any further resources developing this program until (i) the FDA allows the Company to commence a clinical trial in LAPC described in the
−Removed: IND upon which the FDA has placed a clinical hold, (ii) the Company validates the Cell-in-a-Box ®
−Removed: encapsulation technology
−Removed: in our planned Phase 2b clinical trial in LAPC and (iii) the availability of sufficient additional funding, the Company will not be spending
−Removed: any further resources developing this program.
−Removed: Finally, the Company had licensed (“Hai
−Removed: Kang License Agreement”) from Hai Kang Life Corporation (“Hai Kang”) the right to certain technology owned or controlled
−Removed: by Hai Kang related to SARS-Cov2 COVID-19 diagnostic kits (“Kits”).
−Removed: On November 19, 2020, the Company terminated the Hai Kang
−Removed: License Agreement.
+Added: prodrug into its cancer-killing form.
+Added: The Company encapsulates those cells using the Cell-in-a-Box ® technology and places
+Added: those capsules in the body as close as possible to the tumor.
+Added: In this way, the Company believes that when a cancer prodrug is administered
+Added: to a patient with a particular type of cancer that may be affected by the prodrug the killing of the patient’s cancerous tumor may
+Added: be optimized.
+Added: The Company is also developing a way to delay the production and accumulation
+Added: of malignant ascites that results from many types of abdominal cancerous tumors.
+Added: The Company’s therapy for malignant ascites involves
+Added: using the same encapsulated cells it employs for pancreatic cancer but placing the encapsulated cells in the peritoneal cavity of a patient
+Added: and administering ifosfamide intravenously.
+Added: In addition to the two cancer programs discussed
+Added: above, the Company has been working on ways to exploit the benefits of the Cell-in-a-Box ® technology to develop therapies
+Added: for cancer that involve prodrugs based upon certain constituents of the Cannabis plant.
+Added: However, until the FDA allows us to commence
+Added: our clinical trial in LAPC and we are able to validate our Cell-in-a-Box ® encapsulation technology in a clinical trial,
+Added: we are not spending any further resources developing our Cannabis Program.
+Added: Finally, the Company has been developing a potential
+Added: therapy for Type 1 diabetes and insulin-dependent Type 2 diabetes.
+Added: The Company’s product candidate for the treatment of diabetes
+Added: consists of encapsulated genetically modified insulin-producing cells.
+Added: The encapsulation will be done using the Cell-in-a-Box ®
+Added: Implanting these encapsulated cells in the body is designed to have them function as a bio-artificial pancreas for purposes
+Added: of insulin production.
Clinical Hold
−Removed: On September 1, 2020, the Company submitted an
−Removed: IND to the FDA for a planned Phase 2b clinical trial in LAPC.
−Removed: Shortly thereafter, the Company received Information Requests from the FDA
−Removed: related to the IND.
−Removed: The Company timely responded to all information requests.
−Removed: On October 1, 2020, the Company received notice
−Removed: that the FDA had placed the IND on clinical hold.
−Removed: On October 30, 2020, the FDA sent a letter to
−Removed: the Company setting forth the reasons for the clinical hold and specific guidance on what the Company must do to have the clinical hold
−Removed: In order to lift the clinical hold, the FDA has
−Removed: informed the Company that it needs to conduct several additional preclinical studies.
−Removed: The FDA also requested additional information
−Removed: regarding several topics, including sequencing data, manufacturing information and product release specifications.
−Removed: In addition, the FDA requested that several items
−Removed: not related to the clinical hold be addressed through the submission of an IND amendment.
−Removed: Specifically, the FDA requested that the Company
−Removed: perform qualification studies for the drug substance filling step to ensure that the product remains sterile and stable during the filling
−Removed: The FDA also requested additional information, discussion and clarification on several other topics.
−Removed: Since October 30, 2020, there has been no further
−Removed: communication with the FDA regarding the clinical hold.
−Removed: The Company has assembled a scientific team to
−Removed: address the FDA requests related to the clinical hold.
−Removed: That team is working through an extensive list of items that the FDA requested.
−Removed: Among other things, the Company has successfully completed a 9-month product stability study, commenced physical parameter testing for
−Removed: CypCaps™
−Removed: and commenced additional studies for the sequence of DNA encoding of its encapsulated cells.
−Removed: The Company has also designed
−Removed: the biocompatibility tests for cytotoxicity, sensitization, irritation, acute systemic toxicity, material-mediated pyrogenicity, subacute/subchronic
−Removed: toxicity, genotoxicity and implantation.
−Removed: In addition, the Company has begun a compression and swelling study of CypCaps™, designed
−Removed: a study to determine if CypCaps™
−Removed: are adversely affected by contrast medium and designed a study to show the catheters used to implant
−Removed: CypCaps™
−Removed: do not adversely impact the encapsulated cells.
−Removed: Impact of the COVID-19 Pandemic on the Company’s Operations
−Removed: The coronavirus SARS-Cov2 pandemic (“COVID-19”)
−Removed: is causing significant, industry-wide delays in clinical trials.
−Removed: Although the Company is not yet in a clinical trial, the Company has
−Removed: filed an IND with the FDA to commence a clinical trial in LAPC.
−Removed: While the IND has been placed on clinical hold by the FDA, the Company
−Removed: has assessed the impact of COVID-19 on its operations.
−Removed: Currently, many clinical trials are being delayed due to COVID-19.
−Removed: There are numerous
−Removed: reasons for these delays.
−Removed: For example, patients have shown a reluctance to enroll or continue in a clinical trial due to fear of exposure
−Removed: to COVID-19 when they are in a hospital or doctor’s office.
−Removed: There are local, regional and state-wide orders and regulations restricting
−Removed: usual normal activity by people.
−Removed: These discourage and interfere with patient visits to a doctor’s office if the visit is not COVID-19
−Removed: Healthcare providers and health systems are shifting their resources away from clinical trials toward the care of COVID-19 patients.
−Removed: The FDA and other healthcare providers are making product candidates for the treatment of COVID-19 a priority over product candidates
−Removed: unrelated to COVID-19.
−Removed: As of the date of the accompanying consolidated financial statements and related footnotes on Form 10-K (“Report”),
−Removed: the COVID-19 pandemic has had an impact upon the Company’s operations, although the Company believes that impact is not material.
−Removed: The impact primarily relates to delays in tasks associated with the preparation of the Company’s responses to the clinical hold,
−Removed: including all requested preclinical studies.
−Removed: There may be further delays in generating responses to the requests from the FDA related
−Removed: to the clinical hold.
−Removed: As a result of the COVID-19 pandemic, commencement
−Removed: of the Company’s planned clinical trial to treat LAPC may be delayed beyond the lifting of the clinical hold should that occur.
−Removed: Also, enrollment may be difficult for the reasons discussed above.
−Removed: In addition, after enrollment in the trial, if patients contract COVID-19
−Removed: during their participation in the trial or are subject to isolation or shelter in place restrictions, this may cause them to drop out
−Removed: of our clinical trial, miss scheduled therapy appointments or follow-up visits or otherwise fail to follow the clinical trial protocol.
−Removed: If patients are unable to follow the clinical trial protocol or if the trial results are otherwise affected by the consequences of the
−Removed: COVID-19 pandemic on patient participation or actions taken to mitigate COVID-19 spread, the integrity of data from the clinical trial
−Removed: may be compromised or not be accepted by the FDA.
−Removed: This could further adversely impact or delay the Company’s clinical development
+Added: On October 1, 2020, we received notice from the
+Added: FDA that it had placed our IND on clinical hold.
+Added: On October 30, 2020, the FDA sent us a letter setting forth the reasons for the clinical
+Added: hold and providing specific guidance on what we must do to have the clinical hold lifted.
+Added: In order to address the clinical hold, the FDA
+Added: has requested that we:
+Added: Provide additional sequencing data and genetic stability studies;
+Added: Conduct a stability study on the Company’s final formulated product candidate as well as the cells from the Company’s Master Cell Bank;
+Added: Evaluate the compatibility of the delivery devices (the prefilled syringe and the microcatheter used to implant the CypCaps ™ ) with the Company’s product candidate for pancreatic cancer;
+Added: Provide additional detailed description of the manufacturing process of the Company’s product candidate for pancreatic cancer;
+Added: Provide additional product release specifications for the Company’s encapsulated cells;
+Added: Demonstrate comparability between the 1 st and 2 nd generation of the Company’s product candidate for pancreatic cancer and ensure adequate and consistent product performance and safety between the two generations;
+Added: Conduct a biocompatibility assessment using the Company’s capsules material;
+Added: Address specified insufficiencies in the Chemistry, Manufacturing and Controls information in the cross-referenced Drug Master File;
+Added: Conduct an additional nonclinical study in a large animal (such as a pig) to assess the safety, activity, and distribution of the product candidate for pancreatic cancer;
+Added: Revise the Investigators Brochure to include any additional preclinical studies conducted in response to the clinical hold and remove any statements not supported by the data the Company generated.
+Added: The FDA also requested that the Company address
+Added: the following issues as an amendment to the Company’s IND:
+Added: Provide a Certificate of Analysis for pc3/2B1 plasmid that includes tests for assessing purity, safety, and potency;
+Added: Perform qualification studies for the drug substance filling step to ensure that the Company’s product candidate for pancreatic cancer remains sterile and stable during the filling process;
+Added: Submit an updated batch analysis for the Company’s product candidate for the specific lot that will be used for manufacturing all future product candidates;
+Added: Provide additional details for the methodology for the Resorufin (CYP2B1) potency and the PrestoBlue cell metabolic assays;
+Added: Provide a few examples of common microcatheters that fit the specifications in the Company’s Angiography Procedure Manual;
+Added: Clarify the language in our Pharmacy Manual regarding proper use of the syringe fill with the Company’s product candidate for pancreatic cancer;
+Added: Provide a discussion with data for trial of the potential for cellular and humoral immune reactivity against the heterologous rat CYP2B1 protein and potential for induction of autoimmune-mediated toxicities in our study population.
+Added: The Company assembled a scientific and regulatory
+Added: team of experts to address the FDA requests.
+Added: That team has been working diligently to complete the items requested by the FDA.
+Added: is in the latter stages of conducting the studies and providing the information requested by the FDA.
+Added: Impact of the COVID-19 Pandemic on the Company’s
+Added: COVID-19 continues to cause uncertainty and significant,
+Added: industry-wide delays in clinical trials.
+Added: The availability of vaccines holds promise for the future;
+Added: however, new variants of the virus
+Added: and potential waning immunity from vaccines may result in continued impact from COVID-19 in the future, which could adversely impact our
+Added: Although the Company is not yet in a clinical trial, the Company has filed an IND with the FDA to commence a clinical trial
+Added: While the IND has been placed on clinical hold by the FDA, the Company has assessed the impact of COVID-19 on its operations.
+Added: Many clinical trials have been delayed due to
+Added: There are numerous reasons for these delays.
+Added: For example, patients have shown a reluctance to enroll or continue in a clinical
+Added: trial due to fear of exposure to COVID-19 when they are in a hospital or doctor’s office.
+Added: There are local, regional and state-wide
+Added: orders and regulations restricting usual normal activity by people.
+Added: These discourage and interfere with patient visits to a doctor’s
+Added: office if the visit is not COVID-19 related.
+Added: Healthcare providers and health systems have shifted their resources away from clinical trials
+Added: toward the care of COVID-19 patients.
+Added: The FDA and other healthcare providers are making product candidates for the treatment of COVID-19
+Added: a priority over product candidates unrelated to COVID-19.
+Added: As a result of COVID-19 and the mitigation efforts
+Added: to address it, the Company may experience additional disruptions that could adversely impact its business and clinical trial, if allowed
+Added: to proceed, including:
+Added: (i) delays or difficulties in enrolling patients in the Company’s Phase 2b clinical trial if the FDA allows
+Added: the Company to go forward with the trial;
+Added: (ii) delays or difficulties in clinical site activation, including difficulties in recruiting
+Added: clinical site investigators and clinical site personnel;
+Added: (iii) delays in clinical sites receiving the supplies and materials needed to
+Added: conduct the clinical trial, including interruption in global shipping that may affect the transport of the Company’s clinical trial
+Added: (iv) changes in local regulations as part of a response to COVID-19 which may require the Company to change the ways in which
+Added: its clinical trial is to be conducted, which may result in unexpected costs, or to discontinue the clinical trial altogether;
+Added: (v) diversion
+Added: of healthcare resources away from the conduct of clinical trials, including the diversion of hospitals serving as the Company’s
+Added: clinical trial sites and hospital staff supporting the conduct of the Company’s clinical trial;
+Added: (vi) interruption of key clinical
+Added: trial activities, such as clinical trial site monitoring, due to limitations on travel imposed or recommended by federal or state governments,
+Added: employers and others, or interruption of clinical trial subject visits and study procedures, the occurrence of which could affect the
+Added: integrity of clinical trial data;
+Added: (vii) risk that participants enrolled in our clinical trials will acquire COVID-19 while the clinical
+Added: trial is ongoing, which could impact the results of the clinical trial, including by increasing the number of observed adverse events;
+Added: (viii) delays in necessary interactions with local regulators, ethics committees, and other important agencies and contractors due to
+Added: limitations in employee resources or forced furlough of government employees;
+Added: (ix) limitations in employee resources that would otherwise
+Added: be focused on the conduct of the Company’s clinical trial because of sickness of employees or their families or the desire of employees
+Added: to avoid contact with large groups of people;
+Added: (x) refusal of the FDA to accept data from clinical trials in affected geographies;
+Added: (xi) interruption or delays to the Company’s clinical trial activities.
+Added: As a result of COVID-19, commencement of the Company’s
+Added: clinical trial to treat LAPC may be delayed beyond the lifting of the clinical hold by the FDA should that occur.
+Added: Also, enrollment may
+Added: be difficult for the reasons discussed above.
+Added: In addition, after enrollment in the trial, if patients contract COVID-19 during their participation
+Added: in the trial or are subject to isolation or shelter in place restrictions, this may cause them to drop out of our clinical trial, miss
+Added: scheduled therapy appointments or follow-up visits or otherwise fail to follow the clinical trial protocol.
+Added: If patients are unable to
+Added: follow the clinical trial protocol or if the trial results are otherwise affected by the consequences of COVID-19 on patient participation
+Added: or actions taken to mitigate COVID-19 spread, the integrity of data from the clinical trial may be compromised or not be accepted by the
+Added: This could further adversely impact or delay the Company’s clinical development program if the FDA allows it to proceed.
+Added: Clinical trials in the biopharma industry may
+Added: be delayed due to COVID-19.
+Added: There are numerous reasons for these potential delays.
+Added: The impact relates to delays in:
+Added: (i) completing studies
+Added: required by the FDA;
+Added: (ii) manufacturing a new batch of CypCap™ for the Company’s planned clinical trial in LAPC;
+Added: (iii) manufacturing
+Added: syringes of CypCaps™ for some of the Company’s preclinical studies to be completed and for use in the Company’s Malignant
+Added: Ascites Program;
+Added: and (iv) securing third party contractors to conduct various R&D projects for the Company.
+Added: As a result, there may
+Added: be delays in generating responses to the requests from the FDA related to the clinical hold.
+Added: Many of these potential delays are also due
+Added: to the impact of COVID-19 in foreign countries where the Company is conducting these preclinical studies, including India, Europe, Singapore
+Added: and Thailand.
+Added: There have also been supply chain interruptions due to COVID-19.
It is highly speculative in projecting the effects
−Removed: of COVID-19 on the Company’s clinical development program and the Company generally.
−Removed: The effects of COVID-19 quickly and dramatically
−Removed: change over time.
−Removed: Its evolution is difficult to predict, and no one is able to say with certainty when the pandemic will subside.
+Added: of COVID-19 on the Company’s proposed clinical development program and the Company generally.
+Added: Moreover, the various precautionary
+Added: measures taken by many governmental authorities around the world in order to limit the spread of COVID-19 has had and may continue to
+Added: have an adverse effect on the global markets and global economy, including on the availability and pricing of employees, resources, materials,
+Added: manufacturing and delivery efforts and other aspects of the global economy.
+Added: The continuation of COVID-19 could materially disrupt the
+Added: Company’s business and operations, hamper its ability to raise additional funds or sell securities, continue to slow down the overall
+Added: economy, curtail consumer spending, interrupt the Company’s sources of supply, and make it hard to adequately staff the Company’s
+Added: The effects of COVID-19 quickly and dramatically change over time.
+Added: Its evolution is difficult to predict, and no one is able
+Added: to say with certainty when the pandemic will cease to have an impact on the Company’s operations.
Company Background
7 unchanged sentences
to reflect the nature of its current business.
+Added: In October 2021, the Company moved
+Added: its headquarters to Las Vegas, Nevada.
+Added: Nasdaq Listing
+Added: The Company’s common stock began trading
+Added: on Nasdaq on August 10, 2021, under the symbol “PMCB.” Prior to that, the Company’s common stock was quoted on the OTCQB
+Added: Market under the symbol “PMCB.” Following the reverse stock split (discussed below) of the Company’s common stock on
+Added: July 12, 2021, and until August 6, 2021, the OTCQB Market Symbol for the Company’s common stock had been “PMCBD.” Thereafter,
+Added: it reverted to “PMCB.”
Reverse Stock Split
−Removed: Effective July 12, 2021, pursuant to the approval
−Removed: by the Board of Directors, the Company filed with the Secretary of State of Nevada a Certificate of Change to the Articles of Incorporation,
−Removed: to effect a 1-for-1,500 reverse stock split of the Company’s common stock.
−Removed: The reverse stock split decreased the number of authorized
−Removed: shares of common stock as of April 30, 2021, to 1,660,000 shares, with a par value of $0.0001 per share.
−Removed: Except as otherwise indicated,
−Removed: all share and per share information in the accompanying consolidated financial statements and related footnotes gives effect to the reverse stock split of the Company common stock.
−Removed: NOTE 2 –
−Removed: SUMMARY OF SIGNIFICANT ACCOUNTING
+Added: Effective July 12, 2021, the Company filed a Certificate
+Added: of Change with the Nevada Secretary of State that authorized a 1:1500 reverse stock split of the Company’s common stock.
+Added: stock split resulted in reducing the authorized number of shares of the Company’s common stock from 50 billion to thirty-three million
+Added: three hundred thirty-three thousand three hundred thirty-four with a par value of $ 0.0001 per share.
+Added: Any fractional shares resulting from
+Added: the reverse stock split were rounded up to the next whole share.
+Added: All warrants, option, share and per share information in this Report
+Added: gives retroactive effect to such 1:1500 reverse stock split.
+Added: NOTE 2 – SUMMARY OF SIGNIFICANT ACCOUNTING
Principles of Consolidation and Basis of Presentation
−Removed: The consolidated financial statements
−Removed: include the accounts of the Company and its wholly owned subsidiaries.
−Removed: The Company operates independently and through four wholly
−Removed: owned subsidiaries:
+Added: The Consolidated Financial Statements include
+Added: the accounts of the Company and its wholly owned subsidiaries.
+Added: The Company operates independently and through four wholly owned subsidiaries:
(i) Bio Blue Bird;
1 unchanged sentence
(iii) PharmaCyte Biotech Australia Pty.
−Removed: (iv) Viridis Biotech, Inc.
+Added: and (iv) Viridis Biotech, Inc.
and are prepared in accordance with U.S.
GAAP and the Rules and Regulations of the Commission.
−Removed: consolidation, intercompany balances and transactions are eliminated.
−Removed: The Company’s 14.5% investment in SG Austria is
−Removed: presented on the cost method of accounting.
+Added: Upon consolidation, intercompany balances
+Added: and transactions are eliminated.
+Added: The Company’s 14.3 % investment in SG Austria is presented on the cost method of accounting.
Use of Estimates in the Preparation of Financial
4 unchanged sentences
Uncertainties with respect to such estimates and assumptions are inherent in the preparation
−Removed: of the Company’s consolidated financial statements;
+Added: of the Company’s consolidated financial statements;
accordingly, it is possible that the actual results could differ from these
−Removed: estimates and assumptions, which could have a material effect on the reported amounts of the Company’s consolidated financial position
+Added: estimates and assumptions, which could have a material effect on the reported amounts of the Company’s consolidated financial position
and results of operations.
−Removed: The severity, magnitude and duration, as well as the economic consequences of the COVID-19 pandemic, are uncertain,
−Removed: rapidly changing and difficult to predict.
−Removed: Therefore, the Company’s accounting estimates and assumptions may change over time in
−Removed: response to the COVID-19 pandemic and may change materially in future periods.
+Added: The severity, magnitude and duration, as well as the economic consequences of COVID-19, are uncertain, rapidly
+Added: changing and difficult to predict.
+Added: Therefore, the Company’s accounting estimates and assumptions may change over time in response
+Added: to COVID-19 and may change materially in future periods.
+Added: Cash and Cash Equivalents
+Added: Cash and cash equivalents include cash in banks
+Added: and short-term liquid investments purchased with maturities of three months or less.
Intangible Assets
−Removed: The Financial Accounting Standards Board ("FASB")
+Added: The Financial Accounting Standards Board (“FASB”)
standard on goodwill and other intangible assets prescribes a two-step process for impairment testing of goodwill and indefinite-lived
4 unchanged sentences
reporting year.
−Removed: The Company’s intangible assets are licensing
−Removed: agreements related to the Cell-in-a-Box ®
−Removed: technology for $1,549,427 and diabetes license for $2,000,000 for an aggregate
+Added: The Company’s intangible assets are licensing
+Added: agreements related to the Cell-in-a-Box ® technology for $ 1,549,427 and diabetes license for $ 2,000,000 for an aggregate
total of $ 3,549,427 .
12 unchanged sentences
Fair Value of Financial Instruments
−Removed: For certain of the Company’s non-derivative
+Added: For certain of the Company’s non-derivative
financial instruments, including cash, accounts payable and accrued expenses, the carrying amount approximates fair value due to the short-term
maturities of these instruments.
−Removed: Accounting Standards Codification ("ASC")
−Removed: Topic 820, “Fair Value Measurements and Disclosures,”
−Removed: requires disclosure of the fair value of financial instruments held
+Added: Accounting Standards Codification (“ASC”)
+Added: Topic 820, “Fair Value Measurements and Disclosures,” requires disclosure of the fair value of financial instruments held
by the Company.
−Removed: ASC Topic 825, “Financial Instruments,”
−Removed: defines fair value, and establishes a three-level valuation hierarchy
+Added: ASC Topic 825, “Financial Instruments,” defines fair value, and establishes a three-level valuation hierarchy
for disclosures of fair value measurement that enhances disclosure requirements for fair value measures.
5 unchanged sentences
Observable inputs such as quoted prices in active markets;
−Removed: Inputs, other than the quoted prices in active markets, that are observable either directly or indirectly;
+Added: Inputs, other than the quoted prices in active markets, which are observable either directly or indirectly;
Unobservable inputs in which there is little or no market data, which require the reporting entity to develop its own assumptions.
9 unchanged sentences
A valuation allowance is provided for deferred
−Removed: income tax assets when, in management’s judgment, based upon currently available information and other factors, it is more likely
+Added: income tax assets when, in management’s judgment, based upon currently available information and other factors, it is more likely
than not that all or a portion of such deferred income tax assets will not be realized.
8 unchanged sentences
In determining when to
−Removed: release the valuation allowance established against the Company’s net deferred income tax assets, the Company considers all available
+Added: release the valuation allowance established against the Company’s net deferred income tax assets, the Company considers all available
evidence, both positive and negative.
−Removed: Consistent with the Company’s policy, and because of the Company’s history of operating
+Added: Consistent with the Company’s policy, and because of the Company’s history of operating
losses, the Company does not currently recognize the benefit of all its deferred tax assets, including tax loss carry forwards, which
20 unchanged sentences
On March 27, 2020, Congress enacted the Coronavirus
−Removed: Aid, Relief and Economic Security ("CARES") Act to provide certain relief as a result of the Coronavirus Disease 2019 outbreak.
+Added: Aid, Relief and Economic Security ("CARES") Act to provide certain relief as a result of the Coronavirus Disease 2019 outbreak.
The Company maintains a full valuation allowance on its U.S.
1 unchanged sentence
Deferred tax asset remeasurement (tax expense) was
−Removed: offset by a net decrease in valuation allowance, that resulted in no impact on the Company's income tax expense.
+Added: offset by a net decrease in valuation allowance, which resulted in no impact on the Company's income tax expense.
Therefore, the Company
−Removed: does not expect the provisions in the CARES Act will impact the Company’s consolidated financial statements.
+Added: does not expect the provisions in the CARES Act will impact the Company’s consolidated financial statements.
On March 11, 2021, Congress enacted the American
−Removed: Rescue Plan Act of 2021, the Company does not expect the provisions of this act will impact the Company’s consolidated financial
+Added: Rescue Plan Act of 2021, the Company does not expect the provisions of this Act will impact the Company’s consolidated financial
Research and Development
−Removed: R&D expenses consist of costs incurred for
−Removed: direct and overhead-related research expenses and are expensed as incurred.
−Removed: Costs to acquire technologies, including licenses, that are
−Removed: utilized in research and development and that have no alternative future use are expensed when incurred.
−Removed: Technology developed for use
−Removed: in the Company’s product candidates is expensed as incurred until technological feasibility has been established.
+Added: Research and development expenses consist of costs
+Added: incurred for direct and overhead-related research expenses and are expensed as incurred.
+Added: Costs to acquire technologies, including licenses,
+Added: which are utilized in research and development and that have no alternative future use are expensed when incurred.
+Added: Technology developed
+Added: for use in the Company’s product candidates is expensed as incurred until technological feasibility has been established.
R&D costs for the years ended April 30, 2022,
21 unchanged sentences
Deposit Insurance Corporation up to $250,000.
−Removed: Uninsured balances aggregated approximately $1,921,000 and $618,000 at April 30, 2021 and
−Removed: 2020, respectively.
+Added: Uninsured balances aggregated approximately $ 35,000,000 and $ 1,912,000 at April 30, 2022
+Added: and 2021, respectively.
The Company has not experienced any losses in such accounts.
2 unchanged sentences
Foreign Currency Translation
−Removed: The Company translates the financial
−Removed: statements of its foreign subsidiaries from the local (functional) currencies to U.S.
−Removed: dollars in accordance with FASB ASC 830, Foreign
−Removed: Currency Matters .
−Removed: All assets and liabilities of the Company’s foreign subsidiaries are translated at year-end exchange
−Removed: rates, while revenue and expenses are translated at average exchange rates prevailing during the year.
−Removed: Adjustments for foreign
−Removed: currency translation fluctuations are excluded from net loss and are included in other comprehensive income (loss).
−Removed: Gains and losses on
−Removed: short-term intercompany foreign currency transactions are recognized as incurred.
−Removed: Going Concern
−Removed: The accompanying consolidated financial statements
−Removed: have been prepared assuming that the Company will continue as a going concern;
−Removed: however, the following conditions raise substantial doubt
−Removed: about the Company's ability to do so.
−Removed: As of April 30, 2021, the Company has an accumulated deficit of $107,409,495 and incurred
−Removed: a net loss for year ended April 30, 2021 of $3,551,236.
−Removed: The Company requires substantial additional capital to finance its planned business
−Removed: operations and expects to incur operating losses in future periods due to the expenses related to the Company’s core businesses.
−Removed: The Company has not realized any revenue since it commenced doing business in the biotechnology sector, and there can be no assurance
−Removed: that it will be successful in generating revenues in the future in this sector.
−Removed: The consolidated financial statements do not include any
−Removed: adjustments to reflect the possible future effects on the recoverability and classification of assets or the amounts and classifications
−Removed: of liabilities that may result should the Company be unable to continue as a going concern.
−Removed: On April 5, 2021, and with an effective date of
−Removed: April 15, 2021, the Company filed the third Registration Statement on Form S-3 (“Third S-3”).
−Removed: The Third S-3 allows offerings
−Removed: of up to $100 million in transactions that are deemed to be public offerings.
−Removed: On April 26, 2021, the Company entered into an
−Removed: engagement letter with H.C.
−Removed: Wainwright & Co., LLC, as underwriter, with respect to securities to be offered in a public offering.
−Removed: On August 9, 2021, the Company entered into an underwriting agreement with H.C.
−Removed: Wainwright & Co, LLC to offer and sell shares of
−Removed: common stock, pre-funded warrants and warrants in a public offering.
−Removed: The gross proceeds of the offering are expected to be $15 million,
−Removed: before deduction of underwriting discounts, commissions and estimated offering expenses.
−Removed: See Note 13 - Subsequent Events.
−Removed: Management determined that these plans alleviate
−Removed: substantial doubt about the Company’s ability to continue as a going concern.
−Removed: The Company believes the cash on hand at April 30,
−Removed: 2021, the potential sales of registered and unregistered shares of its common stock and the proceeds of the offering led by H.C.
−Removed: & Co., LLC will provide sufficient capital to meet the Company’s capital requirements and to fund the Company’s operations
−Removed: through August 31, 2022.
−Removed: Recent Accounting Pronouncements
−Removed: 2016-13, Financial Instruments - Credit
−Removed: Losses (Topic 326):
−Removed: Measurement of Credit Losses on Financial Instruments ("ASU 2016-13"), was issued in June 2016.
−Removed: ASU 2016-13, existing guidance on reporting credit losses for trade and other receivables and available for sale debt securities will
−Removed: be replaced with a new forward-looking "expected loss"
−Removed: model that generally will result in the earlier recognition of allowances
−Removed: The Company’s adoption of ASU 2016-13 during the quarter ended July 31, 2020 did not result in an impact on the Company’s
−Removed: consolidated financial statements.
−Removed: As part of the Company’s continuing assessment of the adequacy of ASU 2016-13, there are no factors
−Removed: to be considered at this time since the Company does not have an allowance for credit losses.
−Removed: 2019-12, Simplifying the Accounting
−Removed: for Income Taxes ("ASU 2019-12"), was issued in December 2019.
−Removed: Under ASU 2019-12, the accounting for income taxes is simplified
−Removed: by eliminating certain exceptions and implementing additional requirements which result in a more consistent application of ASC 740.
−Removed: Company is currently in the process of evaluating the impact of adopting ASU 2019-12 in 2021 but it does not expect it to have a material
−Removed: impact on the Company’s consolidated financial statements.
−Removed: In March 2020, the FASB issued ASU 2020-04, Reference
−Removed: Rate Reform (Topic 848):
−Removed: Facilitation of the Effects of Reference Rate Reform on Financial Reporting (“ASU 2020-04”) and also
−Removed: issued subsequent amendments to the initial guidance (collectively, “Topic 848”).
−Removed: Topic 848 is effective for all entities
−Removed: as of March 12, 2020 through December 31, 2022 and provides optional guidance for contract modifications and certain hedging relationships
−Removed: associated with the transition from reference rates that are expected to be discontinued.
−Removed: The Company will adopt Topic 848 when relevant
−Removed: contracts are modified upon transition to alternative reference rates.
−Removed: The Company does not expect the adoption of Topic 848 to have a
−Removed: material impact on the Company’s consolidated financial statements.
−Removed: NOTE 3 –
−Removed: ACCRUED EXPENSES
−Removed: Accrued expenses at April 30, 2021 and 2020 are
−Removed: summarized below:
+Added: The Company translates the financial statements
+Added: of its foreign subsidiaries from the local (functional) currencies to U.S.
+Added: dollars in accordance with FASB ASC 830, Foreign Currency
+Added: All assets and liabilities of the Company’s foreign subsidiaries are translated at year-end exchange rates, while revenue
+Added: and expenses are translated at average exchange rates prevailing during the year.
+Added: Adjustments for foreign currency translation fluctuations
+Added: are excluded from net loss and are included in other comprehensive income (loss).
+Added: Gains and losses on short-term intercompany foreign
+Added: currency transactions are recognized as incurred.
+Added: NOTE 3 – ACCRUED EXPENSES
+Added: Accrued expenses at April 30, 2022, and 2021,
+Added: are summarized below:
+Added: Schedule of accrued expenses
Payroll related costs
Director and Officer insurance financing
−Removed: The Company financed the Director and
−Removed: Officer insurance policy.
−Removed: The term of the policy is from March 8, 2021 through September 8, 2021.
−Removed: The financing agreement has an
−Removed: interest rate of 4.85% per annum and requires eight monthly payments of $12,829.
−Removed: The unpaid balances as of April 30, 2021 and 2020
−Removed: of $50,805 and $113,245, respectively, are included in accrued expenses.
−Removed: NOTE 4 –
−Removed: SMALL BUSINESS ADMINISTRATION
+Added: The Director and Officer Insurance Policy for
+Added: the policy term of September 8, 2021, through September 8, 2022, was paid in full on August 8, 2021.
+Added: The Company financed the Director
+Added: and Officer Insurance Policy for the policy term of March 8, 2021, through September 8, 2021.
+Added: The financing agreement had an interest
+Added: rate of 4.85 % per annum and required eight monthly payments of $ 12,829 .
+Added: The unpaid balances as of April 30, 2022 and 2021, of $ 0 and $ 50,805 ,
+Added: respectively, are included in accrued expenses.
+Added: NOTE 4 – SMALL BUSINESS ADMINISTRATION
– PAYCHECK PROTECTION PROGRAM
−Removed: On March 27, 2020, the Coronavirus Aid, Relief,
−Removed: and Economic Security Act (the “CARES Act”) was enacted to provide financial aid to family and businesses impacted by the
−Removed: COVID-19 pandemic.
−Removed: The Company participated in the CARES Act, and on April 15, 2020, the Company entered into a note payable with
−Removed: a bank under the Small Business Administration (“SBA”), Paycheck Protection Program (“PPP”) in the amount of $75,200.
−Removed: This PPP loan matures on April 15, 2022 with a fixed interest rate of 1% per annum with interest deferred for six months.
−Removed: has an initial term of two years, is unsecured and guaranteed by the SBA.
−Removed: Under the terms of the PPP loan, the Company may apply for forgiveness
−Removed: of the amount due on the PPP loan.
−Removed: The Company used the proceeds from the PPP loan for qualifying expenses as defined in the PPP.
−Removed: Company applied for forgiveness of the PPP loan in accordance with the terms of the Cares Act.
−Removed: The SBA issued a notice of PPP loan forgiveness
−Removed: with an effective date of April 28, 2021, forgiving the entire principal of $75,200 and the accrued interest of $779.
−Removed: The Company is recognizing
−Removed: the forgiveness of the PPP loan and accrued interest as Gain on forgiveness of Paycheck Protection Program loan in the accompanying consolidated
−Removed: statements of operations.
−Removed: NOTE 5 –
−Removed: COMMON STOCK TRANSACTIONS
−Removed: A summary of the Company’s compensatory
+Added: On March 27, 2020, the CARES Act was enacted to
+Added: provide financial aid to family and businesses impacted by COVID-19.
+Added: The Company participated in the CARES Act, and on April 15,
+Added: 2020, the Company entered into a note payable with a bank under the Small Business Administration (“SBA”), Paycheck Protection
+Added: Program (“PPP”) in the amount of $ 75,200 .
+Added: This PPP loan was to mature on April 15, 2022 , with a fixed interest rate of 1 %
+Added: per annum with interest deferred for six months.
+Added: The PPP loan has an initial term of two years, is unsecured and guaranteed by the SBA.
+Added: The Company used the proceeds from the PPP loan
+Added: for qualifying expenses as defined in the PPP.
+Added: The Company also applied for forgiveness of the PPP loan in accordance with the terms of
+Added: the CARES Act.
+Added: The SBA issued a notice of PPP loan forgiveness with an effective date of April 28, 2021, forgiving the entire principal
+Added: of $ 75,200 and the accrued interest of $ 779 .
+Added: The Company recognized the forgiveness of the PPP loan and accrued interest as Gain on forgiveness
+Added: of Paycheck Protection Program loan in the fiscal year ended April 30, 2021.
+Added: NOTE 5 – COMMON STOCK TRANSACTIONS
+Added: A summary of the Company’s compensatory
stock activity and related weighted average grant date fair value information for the years ended April 30, 2022, and 2021, are as follows:
−Removed: During the year ended April 30, 2019, the Company
−Removed: issued 2,967 shares of common stock to four consultants.
−Removed: The shares vest monthly over a twelve-month period and are subject to the consultants
−Removed: providing services under the agreements.
−Removed: The Company recorded a non-cash consulting expense in the amount of $0 and $24,726 for the years
−Removed: ended April 30, 2021 and 2020, respectively.
−Removed: There were zero unvested shares as of April 30, 2021 and 2020, respectively.
−Removed: In January 2019, the Company awarded 4,400 shares
−Removed: of common stock to officers as part of their compensation agreements for 2019.
−Removed: These shares vest monthly over a twelve-month period and
−Removed: are subject to them continuing service under the agreements.
−Removed: During the years ended April 30, 2021 and 2020, the Company recorded a non-cash
−Removed: compensation expense in the amount of $0 and $278,891, respectively.
+Added: In January 2020, the Company awarded 4,400
+Added: shares of common stock to the executive officers of the Company as part of their compensation agreements for 2020.
+Added: vest monthly over a twelve-month period and are subject to them continuing service under the agreements.
+Added: During the years ended April
+Added: 30, 2022, and 2021, the Company recorded a non-cash compensation expense in the amount of $ 0
+Added: and $ 179,521 ,
+Added: respectively.
There were zero unvested shares as of April 30, 2022, and 2021, respectively.
−Removed: During the year ended April 30, 2020, four non-employee
−Removed: members of the Board were issued 1,333 shares of common stock pursuant to their respective Director Letter Agreement (“DLAs”)
−Removed: and relating to their services for the prior year.
−Removed: The shares were fully vested upon issuance.
−Removed: The Company recorded a non-cash expense
−Removed: of $0 and $19,212 for the years ended April 30, 2021 and 2020, respectively.
−Removed: There were zero unvested shares of common stock remaining
−Removed: related to these DLAs as of April 30, 2021 and 2020, respectively.
−Removed: During the year ended April 30, 2020, a consultant
−Removed: was issued 1,667 shares of common stock in respect of his services as the Chairman of the Company’s Medical and Scientific Advisory
−Removed: Board over a five-year period vested upon issuance are subject to the consultant providing services to the Company.
−Removed: The Company recorded
−Removed: a non-cash consulting expense in the amount of $0 and $22,584 for the years ended April 30, 2021 and 2020, respectively.
−Removed: There were zero
−Removed: unvested shares remaining related to his compensation agreements as of April 30, 2021 and 2020, respectively.
−Removed: During the year ended April 30, 2020, the four
−Removed: non-employee members of the Board were issued 1,333 shares of common stock pursuant to their DLAs in respect of their service during that
−Removed: The shares were fully vested upon issuance.
−Removed: The Company recorded a non-cash expense of $0 and $65,339 for the years ended April
−Removed: 30, 2021 and 2020, respectively.
−Removed: There were zero unvested shares remaining related to a DLA as of April 30, 2021 and 2020, respectively.
−Removed: During the year ended April 30, 2020, five consultants
−Removed: were issued 2,133 shares of restricted common stock pursuant to their respective consulting agreement with the Company.
−Removed: The terms of the
−Removed: agreements are for twelve months.
−Removed: The share issuances covered current and prior years.
−Removed: The shares vest monthly over a twelve-month period
−Removed: and are subject to the consultants providing services under the consultant’s respective consulting agreement.
−Removed: The Company recorded
−Removed: a non-cash consulting expense in the amount of $0 and $108,575 for the years ended April 30, 2021 and 2020, respectively.
−Removed: There were zero
−Removed: and 133 unvested shares remaining related to these consulting agreements as of April 30, 2021 and 2020, respectively.
+Added: During the year ended April 30, 2021, four
+Added: non-employee members of the Board were issued 1,333 shares
+Added: of common stock pursuant to their Director Letter Agreements (“DLAs”) in respect of their service during that year.
+Added: shares were fully vested upon issuance.
+Added: The Company recorded a non-cash expense of $ 4,342 and
+Added: the years ended April 30, 2022, and 2021, respectively.
+Added: There were zero unvested shares remaining related to such DLAs as of April
+Added: 30, 2022, and 2021.
+Added: During the year ended April 30, 2021, four
+Added: consultants were issued 667 shares
+Added: of common stock pursuant to their consulting agreements with the Company.
+Added: The shares vest monthly over a twelve-month period and are
+Added: subject to the consultants continuing to provide services under their consulting agreements.
+Added: The Company recorded a non-cash
+Added: consulting expense in the amount of $ 0 and
+Added: the years ended April 30, 2022, and 2021, respectively.
+Added: There were zero unvested shares remaining related to these consulting
+Added: agreements as of April 30, 2022, and 2021.
+Added: During the year ended April 30, 2021, a
+Added: consultant was issued 333 shares
+Added: of common stock in respect of his services as the Chairman of the Company’s Medical and Scientific Advisory Board with vesting
+Added: subject to the consultant continuing to provide services to the Company.
+Added: The Company recorded a non-cash consulting expense in the
+Added: amount of $ 3,542 and
+Added: the years ended April 30, 2022, and 2021, respectively.
+Added: There were zero unvested shares remaining related to his compensation
+Added: arrangement as of April 30, 2022, and 2021.
In January 2021, the Company awarded 4,400 shares
of common stock to the executive officers of the Company as part of their compensation agreements for 2021.
−Removed: These shares vest monthly
−Removed: over a twelve-month period and are subject to them continuing service under the agreements.
−Removed: During the years ended April 30, 2021 and
−Removed: 2020, the Company recorded a non-cash compensation expense in the amount of $179,521 and $89,759, respectively.
−Removed: There were zero and 2,933
−Removed: unvested shares as of April 30, 2021 and 2020, respectively.
−Removed: During the year ended April 30, 2020, the Company
−Removed: entered into four stock subscription agreements resulting in the sale and issuance of 68,667 shares of restricted common stock.
−Removed: received $515,000 from the sale of these shares.
+Added: These shares vest
+Added: monthly over a twelve-month period and are subject to the executive officers continuing to provide service under their compensation
+Added: During the years ended April 30, 2022, and 2021, the Company recorded a non-cash compensation expense in the amounts of
+Added: respectively.
+Added: There were zero and 2,933 unvested
+Added: shares as of April 30, 2022, and 2021, respectively.
During the year ended April 30, 2022, four non-employee
1 unchanged sentence
shares were fully vested upon issuance.
−Removed: The Company recorded a non-cash expense of $37,258 for the year ended April 30, 2021, respectively.
−Removed: There were zero unvested shares remaining related to such DLAs as of April 30, 2021.
−Removed: During the year ended April 30, 2021, four consultants
−Removed: were issued 667 shares of common stock pursuant to their consulting agreements with the Company.
−Removed: The shares vest monthly over a twelve-month
−Removed: period and are subject to the consultants continuing to provide services under their consulting agreements.
+Added: The Company recorded a non-cash expense of $ 24,212 for the year ended April 30, 2022.
+Added: zero unvested shares remaining related to such DLAs as of April 30, 2022, and 2021.
+Added: During the year ended April 30, 2022, four
+Added: consultants were issued 668 shares
+Added: of common stock pursuant to their consulting agreements with the Company.
+Added: The shares vest monthly over a twelve-month period and are
+Added: subject to the consultants continuing to provide services under their consulting agreements.
The Company recorded a non-cash
−Removed: consulting expense in the amount of $20,225 for the year ended April 30, 2021.
−Removed: There were zero unvested shares remaining related to these
−Removed: consulting agreements as of April 30, 2021.
−Removed: During the year ended April 30, 2021, a consultant
−Removed: was issued 333 shares of common stock in respect of his services as the Chairman of the Company’s Medical and Scientific Advisory
−Removed: Board with vesting subject to the consultant continuing to provide services to the Company.
−Removed: The Company recorded a non-cash consulting
−Removed: expense in the amount of $4,958 for the year ended April 30, 2021.
−Removed: There were zero unvested shares remaining related to his compensation
−Removed: arrangement as of April 30, 2021.
+Added: consulting expense in the amount of $ 9,576 for
+Added: the year ended April 30, 2022.
+Added: There were zero unvested shares remaining related to these consulting agreements as of April 30,
+Added: During the year ended April 30, 2022, a
+Added: consultant was issued 334 shares
+Added: of common stock in respect of his services as the Chairman of the Company’s Medical and Scientific Advisory Board with vesting
+Added: subject to the consultant continuing to provide services to the Company.
+Added: The Company recorded a non-cash consulting expense in the
+Added: amount of $ 1,059 for
+Added: the year ended April 30, 2022.
+Added: There were zero unvested shares remaining related to his compensation arrangement as of April 30,
In January 2022, the Company awarded 4,400 shares
10 unchanged sentences
the Securities Act in reliance upon the exemption afforded by Section 4(a)(2) of the Securities Act.
−Removed: On September 28, 2017, the Second S-3 was declared
−Removed: effective by the Commission for a public offering of up to $50 million on a “shelf offering”
−Removed: During the years ended
−Removed: April 30, 2021 and 2020, the Company sold and issued approximately 462,000 and 222,000 shares of common stock, respectively, at prices
−Removed: ranging from approximately $15 to $45 per share.
−Removed: Net of underwriting discounts, legal, accounting and other offering expenses, the Company
−Removed: received proceeds of approximately $4.7 and $2.1 million from the sale of these shares for the years ended April 30, 2021 and 2020, respectively.
−Removed: A summary of the Company’s non-vested restricted
+Added: On September 28, 2017, an S-3 Registration
+Added: Statement (“Second S-3”) was declared effective by the Commission for the Company to sell from time to time in one or more
+Added: public offerings of up to $50 million of its securities on a “shelf offering” basis.
+Added: During the year ended April 30, 2021,
+Added: the Company sold and issued approximately 462,000 shares of common stock, at prices ranging from approximately $15 to $45 per share.
+Added: of underwriting discounts, legal, accounting, and other offering expenses, the Company received proceeds of approximately $ 4.7 million
+Added: from the sale of these shares for the year ended April 30, 2021.
+Added: On April 9, 2021, the Third S-3 (“Third S-3”) was declared
+Added: effective by the Commission for a public offering of up to $100 million on a “shelf offering” basis.
+Added: During the year ended
+Added: April 30, 2022, the Company sold and issued approximately 19.1 million shares of common stock, at prices ranging from $4.25 to $5.00 per
+Added: Net of underwriting discounts, legal, accounting, and other offering expenses, the Company received approximately $ 87.4 million
+Added: from the sale of these shares and the exercise of approximately 2.5 million warrant shares for the year ended April 30, 2022.
+Added: A summary of the Company’s non-vested restricted
stock activity and related weighted average grant date fair value information for the last two years ended April 30, 2022, are as follows:
+Added: Schedule of non-vested restricted stock activity
Unvested, at April 30, 2020
1 unchanged sentence
Unvested, at April 30, 2022
−Removed: NOTE 6 –
−Removed: STOCK OPTIONS AND WARRANTS
+Added: NOTE 6 – STOCK OPTIONS AND WARRANTS
+Added: 2021 Equity Incentive Plan
+Added: Effective June 30, 2021, the Company implemented
+Added: the 2021 Equity Incentive Plan (“2021 Equity Plan”) as approved by the Company’s stockholders.
+Added: The 2021 Equity Plan
+Added: is administered by the Compensation Committee of the Board and has 166,667 shares available under this plan.
+Added: The 2021 Equity Plan can
+Added: issue various types of awards, as follows:
+Added: stock options, stock appreciation rights, restricted stock, restricted stock units, and cash
+Added: or other stock-based awards.
+Added: The 2021 Equity Plan is available to be issued to employees, directors, consultants, and other individuals
+Added: who provide services to the Company.
+Added: An incentive stock options (“ISOs”) can only be granted to employees and shall not exceed
+Added: 10-years (5-years in the case of ISOs granted to any 10% shareholder).
Stock Options
−Removed: As of April 30, 2021, the Company had 41,333 outstanding
−Removed: stock options to its directors and officers (collectively, “Employee Options”) and consultants (“Non-Employee Options”).
+Added: As of April 30, 2022, the Company had 40,900
+Added: outstanding stock options to its directors and officers (collectively, “Employee Options”) and consultants
+Added: (“Non-Employee Options”).
During the years ended April 30, 2022, and 2021,
2 unchanged sentences
date of grant was estimated using the Black-Scholes-Merton option-pricing model, based on the following weighted average assumptions:
+Added: Assumptions for options
Years Ended April 30,
3 unchanged sentences
Expected dividend yield
−Removed: The Company’s computation of expected
−Removed: volatility is based on the historical daily volatility of its publicly traded stock.
−Removed: For stock option grants issued during the years
−Removed: ended April 30, 2021 and 2020, the Company used a calculated volatility for each grant.
−Removed: The Company lacks adequate information about
−Removed: the exercise behavior now and has determined the expected term assumption under the simplified method provided for under ASC 718,
−Removed: which averages the contractual term of the Company’s stock options of five years with the average vesting term of two and
−Removed: one-half years for an average of three years.
−Removed: The dividend yield assumption of zero is based upon the fact the Company has never
−Removed: paid cash dividends and presently has no intention of paying cash dividends.
−Removed: The risk-free interest rate used for each grant is
−Removed: equal to the U.S.
−Removed: Treasury rates in effect at the time of the grant for instruments with a similar expected life.
+Added: The Company’s computation of expected volatility
+Added: is based on the historical daily volatility of its publicly traded stock.
+Added: For stock option grants issued during the years ended April
+Added: 30, 2022, and 2021, the Company used a calculated volatility for each grant.
+Added: The Company lacks adequate information about the exercise
+Added: behavior now and has determined the expected term assumption under the simplified method provided for under ASC 718, which averages the
+Added: contractual term of the Company’s stock options of five years with the average vesting term of two and one-half years for an average
+Added: of three years.
+Added: The dividend yield assumption of zero is based upon the fact the Company has never paid cash dividends and presently has
+Added: no intention of paying cash dividends.
+Added: The risk-free interest rate used for each grant is equal to the U.S.
+Added: Treasury rates in effect at
+Added: the time of the grant for instruments with a similar expected life.
During the years ended April 30, 2022, and 2021,
−Removed: the Company granted Non-Employee Options of zero and 800, respectively.
−Removed: The fair value of the Non-Employee Options was
−Removed: estimated using the Black-Scholes-Merton option-pricing model, based on the following weighted average assumptions:
−Removed: Years Ended April 30,
−Removed: Risk-free interest rate
−Removed: Expected volatility
−Removed: Expected lives (years)
−Removed: Expected dividend yield
−Removed: Non-Employee Option grants that do not vest immediately
−Removed: upon grant are recorded as an expense over the vesting period.
−Removed: Effective August 1, 2018, the Company adopted ASU 2018-07 early using the
−Removed: modified retrospective transition approach.
−Removed: The Company determined there was no transition adjustment upon adoption of ASU 2018-07.
−Removed: A summary of the Company’s stock option
+Added: the Company granted no Non-Employee Options.
+Added: A summary of the Company’s stock option
activity and related information for the two years ended April 30, 2022 are shown below:
−Removed: Exercise Price
+Added: Schedule of stock option activity
+Added: Price per Share
Outstanding, April 30, 2020
3 unchanged sentences
Vested and expected to vest
−Removed: A summary of the activity for unvested stock options
−Removed: during the years ended April 30, 2021 and 2020 is as follows:
+Added: A summary of the activity for unvested stock
+Added: options during the years ended April 30, 2022, and 2021 is as follows:
+Added: Unvested stock option activity
Unvested, April 30, 2020
1 unchanged sentence
Unvested, April 30, 2022
−Removed: The Company recorded $176,568 and $338,051 of
−Removed: stock-based compensation related to the issuance of Employee Options to certain officers and directors in exchange for services during
−Removed: the years ended April 30, 2021 and 2020, respectively.
−Removed: At April 30, 2021, there remained $25,562 of unrecognized compensation expense
−Removed: related to unvested Employee Options granted to officers and directors, to be recognized as expense over a weighted-average period of
−Removed: the remaining eight months in the calendar year.
−Removed: The unvested options vest at 500 shares per month and are expected to be fully vested
−Removed: on December 31, 2021.
−Removed: The Company recorded $0 and $41,326 of stock-based
−Removed: compensation related to the issuance of Non-Employee Options in exchange for services during the years ended April 30, 2021 and 2020,
−Removed: respectively.
+Added: The Company recorded $ 44,800
+Added: and $ 176,568
+Added: of stock-based compensation related to the issuance of Employee Options to certain officers and directors in exchange for services
+Added: during the years ended April 30, 2022, and 2021, respectively.
+Added: At April 30, 2022, there remained $ 7,777
+Added: of unrecognized compensation expense related to unvested Employee Options granted to officers and directors, to be recognized
+Added: as expense over a weighted-average period of the remaining eight months in the calendar year.
+Added: The unvested options vest at 500 shares
+Added: per month and are expected to be fully vested on December 31, 2022.
The following table summarizes the outstanding
stock options by exercise price at April 30, 2022:
+Added: Schedule of options by exercise price
Exercise Price
2 unchanged sentences
Weighted Average
−Removed: Exercise Price
+Added: Exercise Price Per Share
of Exercisable
1 unchanged sentence
as of April 30, 2022, was $ 0 .
−Removed: This represents options whose exercise price was less than the closing fair market value of the Company’s
+Added: This represents options whose exercise price was less than the closing fair market value of the Company’s
common stock on April 30, 2022, of approximately $ 2.33 per share.
−Removed: The warrants issued by the Company are equity-classified.
+Added: The warrants issued by the Company are equity
The fair value of the warrants was recorded as additional paid-in-capital, and no further adjustments are made.
−Removed: For stock warrants paid in consideration of services
−Removed: rendered by non-employees, the Company recognizes consulting expense in accordance with the requirements of ASC 505.
−Removed: Effective June 13, 2019 the Company issued a common
−Removed: stock purchase warrant to Aeon for a Block Trade.
−Removed: The Company issued a warrant to purchase 893 shares of common stock based upon a Block
−Removed: Trade pursuant to the engagement agreement with Aeon dated February 22, 2018.
−Removed: The Company classified these warrants as equity, and the
−Removed: warrants have a term of five years with an exercise price of approximately $15 per share.
−Removed: Using the Black-Scholes-Merton option pricing
−Removed: model, the Company determined the aggregate value of these warrants to be approximately $9,000.
−Removed: The warrants have a cashless exercise
−Removed: Effective July 15, 2019 the Company issued a common
−Removed: stock purchase warrant to Aeon for a Block Trade.
−Removed: The Company issued a warrant to purchase 1,296 shares of common stock based upon a Block
−Removed: Trade pursuant to the engagement agreement with Aeon dated February 22, 2018.
−Removed: The Company classified these warrants as equity, and the
−Removed: warrants have a term of five years with an exercise price of approximately $15 per share.
−Removed: Using the Black-Scholes-Merton option pricing
−Removed: model, the Company determined the aggregate value of these warrants to be approximately $12,000.
−Removed: The warrants have a cashless exercise
−Removed: Effective August 7, 2019 the Company issued a
−Removed: common stock purchase warrant to Aeon for a Block Trade.
−Removed: The Company issued a warrant to purchase 2,000 shares of common stock based upon
−Removed: a Block Trade pursuant to the engagement agreement with Aeon dated February 22, 2018.
−Removed: The Company classified these warrants as equity,
−Removed: and the warrants have a term of five years with an exercise price of approximately $15 per share.
−Removed: Using the Black-Scholes-Merton option
−Removed: pricing model, the Company determined the aggregate value of these warrants to be approximately $10,000.
−Removed: The warrants have a cashless
−Removed: exercise feature.
−Removed: Effective August 7, 2019 the Company issued a
−Removed: common stock purchase warrant to Aeon for a Block Trade.
−Removed: The Company issued a warrant to purchase 333 shares of common stock based upon
−Removed: a Block Trade pursuant to the engagement agreement with Aeon dated February 22, 2018.
−Removed: The Company classified these warrants as equity,
−Removed: and the warrants have a term of five years with an exercise price of approximately $15 per share.
−Removed: Using the Black-Scholes-Merton option
−Removed: pricing model, the Company determined the aggregate value of these warrants to be approximately $2,000.
−Removed: The warrants have a cashless exercise
−Removed: Effective February 24, 2020 the Company issued
−Removed: a common stock purchase warrant to Aeon for a Block Trade.
−Removed: The Company issued a warrant to purchase 667 shares of common stock based upon
−Removed: a Block Trade pursuant to the engagement agreement with Aeon dated February 22, 2018.
−Removed: The Company classified these warrants as equity,
−Removed: and the warrants have a term of five years with an exercise price of approximately $15 per share.
−Removed: Using the Black-Scholes-Merton option
−Removed: pricing model, the Company determined the aggregate value of these warrants to be approximately $3,000.
−Removed: The warrants have a cashless exercise
−Removed: Effective February 24, 2020 the Company issued
−Removed: a common stock purchase warrant to Aeon for a Block Trade.
−Removed: The Company issued a warrant to purchase 667 shares of common stock based upon
−Removed: a Block Trade pursuant to the engagement agreement with Aeon dated February 22, 2018.
−Removed: The Company classified these warrants as equity,
−Removed: and the warrants have a term of five years with an exercise price of approximately $15 per share.
−Removed: Using the Black-Scholes-Merton option
−Removed: pricing model, the Company determined the aggregate value of these warrants to be approximately $3,000.
−Removed: The warrants have a cashless exercise
−Removed: Effective March 24, 2020 the Company issued a
−Removed: common stock purchase warrant to Aeon for a Block Trade.
−Removed: The Company issued a warrant to purchase 2,333 shares of common stock based upon
−Removed: a Block Trade pursuant to the engagement agreement with Aeon dated February 22, 2018.
−Removed: The Company classified these warrants as equity,
−Removed: and the warrants have a term of five years with an exercise price of approximately $15 per share.
−Removed: Using the Black-Scholes-Merton option
−Removed: pricing model, the Company determined the aggregate value of these warrants to be approximately $12,000.
−Removed: The warrants have a cashless
−Removed: exercise feature.
−Removed: Effective March 31, 2020 the Company issued a
−Removed: common stock purchase warrant to Aeon for a Block Trade.
−Removed: The Company issued a warrant to purchase 667 shares of common stock based upon
−Removed: a Block Trade pursuant to the engagement agreement with Aeon dated February 22, 2018.
−Removed: The Company classified these warrants as equity,
−Removed: and the warrants have a term of five years with an exercise price of approximately $15 per share.
+Added: The Company concluded the following warrants met
+Added: the permanent equity criteria classification as they are freestanding financial instruments that are legally detachable and separately
+Added: exercisable from the shares of common stock with which they were issued.
+Added: The warrants are immediately exercisable and do not embody an
+Added: obligation for the Company to repurchase the shares.
+Added: The warrants also permit the holders to receive a fixed number of shares upon exercise
+Added: and do not provide any guarantee of value or return.
+Added: The Company elected to early adopt ASU No.
+Added: Debt - Debt with Conversion and Other Options (Subtopic 470-20) and Derivatives and Hedging — Contracts in Entity’s Own Equity
+Added: (Subtopic 815-40) as of May 1, 2021.
+Added: The early adoption of ASU No.2020-06 had an immaterial effect on the Company’s consolidated
+Added: financial statements.
+Added: Effective August 12, 2021, the Company issued
+Added: Common Stock Warrant Agreements (“Common Warrants”) with respect to the First Offering.
+Added: The Company issued Common Warrants
+Added: to purchase 4,028,528
+Added: shares of common stock based upon the underwriting agreement with H.C.
+Added: Wainwright & Co., LLC (“Wainwright”).
+Added: Common Warrants have a term of five years with an exercise price of $ 4.25
+Added: per warrant share, are fully vested upon issuance and have a cashless exercise feature.
Using the Black-Scholes-Merton option
−Removed: pricing model, the Company determined the aggregate value of these warrants to be approximately $3,000.
−Removed: The warrants have a cashless exercise
−Removed: Effective April 7, 2020 the Company issued a common
−Removed: stock purchase warrant to Aeon for a Block Trade.
−Removed: The Company issued a warrant to purchase 1,667 shares of common stock based upon a Block
−Removed: Trade pursuant to the engagement agreement with Aeon dated February 22, 2018.
−Removed: The Company classified these warrants as equity, and the
−Removed: warrants have a term of five years with an exercise price of $15 per share.
−Removed: Using the Black-Scholes-Merton option pricing model, the Company
−Removed: determined the aggregate value of these warrants to be approximately $17,000.
−Removed: The warrants have a cashless exercise feature.
−Removed: Effective April 21, 2020 the Company issued a
−Removed: common stock purchase warrant to Aeon for a Block Trade.
−Removed: The Company issued a warrant to purchase 556 shares of common stock based upon
−Removed: a Block Trade pursuant to the engagement agreement with Aeon dated February 22, 2018.
−Removed: The Company classified these warrants as equity,
−Removed: and the warrants have a term of five years with an exercise price of approximately $30 per share.
+Added: pricing model, the Company determined the aggregate fair value of these Common Warrants to be approximately $ 9,385,000
+Added: and comprises the non-cash equity issuance costs as presented on the Consolidated Statements of Cash Flows of $34,477,000.
+Added: Additionally, with respect to the First Offering,
+Added: the Company issued common stock warrant agreements to Wainwright (“Underwriter Warrants”) to purchase 264,706
+Added: shares of common stock.
+Added: The Underwriter Warrants have a term of five years with an exercise price of $ 5.3125
+Added: per warrant share, are fully vested upon issuance and have a cashless exercise feature.
Using the Black-Scholes-Merton option
−Removed: pricing model, the Company determined the aggregate value of these warrants to be approximately $9,000.
−Removed: The warrants have a cashless exercise
−Removed: Effective July 10, 2020, the Company issued a
−Removed: Common Stock Purchase Warrant to Aeon for a Block Trade transaction.
−Removed: The Company issued a warrant to purchase 2,733 shares of common stock
−Removed: based upon the Block Trade pursuant to the Aeon Engagement Agreement.
−Removed: The Company classified these warrants as equity.
−Removed: The warrants have
−Removed: a term of five years with an exercise price of $15 per warrant share.
−Removed: Using the Black-Scholes-Merton option pricing model, the Company
−Removed: determined the aggregate fair value of these warrants to be approximately $29,000.
−Removed: The warrants have a cashless exercise feature.
−Removed: Effective July 18, 2020, the Company issued a
−Removed: Common Stock Purchase Warrant to Aeon for a Block Trade transaction.
−Removed: The Company issued a warrant to purchase 2,333 shares of common stock
−Removed: based upon the Block Trade pursuant to the Aeon Engagement Agreement.
−Removed: The Company classified these warrants as equity.
−Removed: The warrants have
−Removed: a term of five years with an exercise price of approximately $15 per warrant share.
−Removed: Using the Black-Scholes-Merton option pricing model,
−Removed: the Company determined the aggregate fair value of these warrants to be approximately $18,000.
−Removed: The warrants have a cashless exercise feature.
−Removed: Effective July 19, 2020, the Company issued a
−Removed: Common Stock Purchase Warrant to Aeon for a Block Trade transaction.
−Removed: The Company issued a warrant to purchase 889 shares of common stock
−Removed: based upon the Block Trade pursuant to the Aeon Engagement Agreement.
−Removed: The Company classified these warrants as equity.
−Removed: The warrants have
−Removed: a term of five years with an exercise price of approximately $15 per warrant share.
−Removed: Using the Black-Scholes-Merton option pricing model,
−Removed: the Company determined the aggregate fair value of these warrants to be approximately $7,000.
−Removed: The warrants have a cashless exercise feature.
−Removed: Effective July 27, 2020, the Company issued a
−Removed: Common Stock Purchase Warrant to Aeon for a Block Trade transaction.
−Removed: The Company issued a warrant to purchase 1,667 shares of common stock
−Removed: based upon the Block Trade pursuant to the Aeon Engagement Agreement.
−Removed: The Company classified these warrants as equity.
−Removed: The warrants have
−Removed: a term of five years with an exercise price of approximately $15 per warrant share.
−Removed: Using the Black-Scholes-Merton option pricing model,
−Removed: the Company determined the aggregate fair value of these warrants to be approximately $13,000.
−Removed: The warrants have a cashless exercise feature.
−Removed: Effective August 3, 2020, the Company issued a
−Removed: Common Stock Purchase Warrant to Aeon for a Block Trade transaction.
−Removed: The Company issued a warrant to purchase 3,000 shares of common stock
−Removed: based upon the Block Trade pursuant to the Aeon Engagement Agreement.
−Removed: The Company classified these warrants as equity.
−Removed: The warrants have
−Removed: a term of five years with an exercise price of approximately $15 per warrant share.
−Removed: Using the Black-Scholes-Merton option pricing model,
−Removed: the Company determined the aggregate fair value of these warrants to be approximately $24,000.
−Removed: The warrants have a cashless exercise feature.
−Removed: Effective August 6, 2020, the Company issued a
−Removed: Common Stock Purchase Warrant to Aeon for a Block Trade transaction.
−Removed: The Company issued a warrant to purchase 2,733 shares of common stock
−Removed: based upon the Block Trade pursuant to the Aeon Engagement Agreement.
−Removed: The Company classified these warrants as equity.
−Removed: The warrants have
−Removed: a term of five years with an exercise price of $15 per warrant share.
−Removed: Using the Black-Scholes-Merton option pricing model, the Company
−Removed: determined the aggregate fair value of these warrants to be approximately $29,000.
−Removed: The warrants have a cashless exercise feature.
−Removed: Effective August 6, 2020, the Company issued a
−Removed: Common Stock Purchase Warrant to Aeon for a Block Trade transaction.
−Removed: The Company issued a warrant to purchase 3,333 shares of common stock
−Removed: based upon the Block Trade pursuant to the Aeon Engagement Agreement.
−Removed: The Company classified these warrants as equity.
−Removed: The warrants have
−Removed: a term of five years with an exercise price of approximately $15 per warrant share.
−Removed: Using the Black-Scholes-Merton option pricing model,
−Removed: the Company determined the aggregate fair value of these warrants to be approximately $18,000.
−Removed: The warrants have a cashless exercise feature.
−Removed: Effective August 7, 2020, the Company issued a
−Removed: Common Stock Purchase Warrant to Aeon for a Block Trade transaction.
−Removed: The Company issued a warrant to purchase 1,667 shares of common stock
−Removed: based upon the Block Trade pursuant to the Aeon Engagement Agreement.
−Removed: The Company classified these warrants as equity.
−Removed: The warrants have
−Removed: a term of five years with an exercise price of approximately $15 per warrant share.
−Removed: Using the Black-Scholes-Merton option pricing model,
−Removed: the Company determined the aggregate fair value of these warrants to be approximately $13,000.
−Removed: The warrants have a cashless exercise feature.
−Removed: Effective August 7, 2020, the Company issued a
−Removed: Common Stock Purchase Warrant to Aeon for a Block Trade transaction.
−Removed: The Company issued a warrant to purchase 3,667 shares of common stock
−Removed: based upon the Block Trade pursuant to the Aeon Engagement Agreement.
−Removed: The Company classified these warrants as equity.
−Removed: The warrants have
−Removed: a term of five years with an exercise price of approximately $15 per warrant share.
−Removed: Using the Black-Scholes-Merton option pricing model,
−Removed: the Company determined the aggregate fair value of these warrants to be approximately $19,000.
−Removed: The warrants have a cashless exercise feature.
+Added: pricing model, the Company determined the aggregate fair value of these Underwriter Warrants to be approximately $ 601,000
+Added: and comprises the non-cash equity issuance costs as presented on the Consolidated Statements of Cash Flows of $34,477,000.
Effective August 12, 2021, the Company issued
−Removed: a Common Stock Purchase Warrant to Aeon for a Block Trade transaction.
−Removed: The Company issued a warrant to purchase 889 shares of common stock
−Removed: based upon the Block Trade pursuant to the Aeon Engagement Agreement.
−Removed: The Company classified these warrants as equity.
−Removed: The warrants have
−Removed: a term of five years with an exercise price of approximately $15 per warrant share.
−Removed: Using the Black-Scholes-Merton option pricing model,
−Removed: the Company determined the aggregate fair value of these warrants to be approximately $7,000.
−Removed: The warrants have a cashless exercise feature.
−Removed: On March 1, 2021, the Company received notices
−Removed: from Aeon of cashless exercises of their 26 Common Stock Purchase Warrant agreements.
−Removed: The Company issued 29,144 shares of common stock
−Removed: in full settlement of all of the Common Stock Purchase Warrant agreements previously issued to Aeon.
−Removed: The cashless exercise resulted in 40,524 warrant shares to be exercised resulting in a cashless exercise cost
−Removed: of 11,380 shares.
−Removed: A summary of the Company’s warrant activity
+Added: pre-funded warrants (“Pre-funded Warrants”) to purchase common stock and Common Warrants based upon the underwriting
+Added: agreement with Wainwright with respect to the First Offering.
+Added: The Pre-funded Warrants required a payment upon issuance of $4.249 per
+Added: warrant share and are fully vested upon issuance.
+Added: The Company received approximately $ 3,820,000
+Added: from the issuance of the Pre-funded Warrants.
+Added: The Pre-funded Warrants have an exercise price of $0.001 per share, are exercisable
+Added: immediately, have a cashless exercise feature and do not have an expiration date.
+Added: In August 2021, all 899,027
+Added: of the Pre-funded Warrants issued under the underwriting agreement were exercised.
+Added: The Company received $ 899
+Added: as a result of the exercise of the Pre-funded Warrants and issued 899,027 shares of common stock as a result of the exercise notices.
+Added: There was no additional effect on the Pre-funded Warrants as they were fully exercised.
+Added: Effective August 23, 2021, the Company issued
+Added: additional Common Stock Warrant Agreements (“Series A Warrants”) with respect to its Registered Direct Public offering.
+Added: Company issued Series A Warrants to purchase 7,000,000
+Added: shares of common stock based upon the Securities Purchase Agreement with certain institutional investors.
+Added: The Series A Warrants
+Added: have a term of five years with an exercise price of $ 5.00
+Added: per warrant share, are fully vested upon issuance, have a cashless exercise feature and are exercisable immediately.
+Added: Black-Scholes-Merton option pricing model, the Company determined the aggregate fair value of these Series A Warrants to be approximately
+Added: and comprises the non-cash equity issuance costs as presented on the Consolidated Statements of Cash Flows of $34,477,000.
+Added: Effective August 23, 2021, the Company
+Added: issued additional Common Stock Warrant Agreements (“Placement Agent Warrants”) with respect to its Registered Direct
+Added: Public Offering.
+Added: The Company issued Placement Agent Warrants to purchase 1,050,000
+Added: shares of common stock to Wainwright or its designees based upon Wainwright acting as placement agent.
+Added: The Placement Agent Warrants
+Added: have a term of five years with an exercise price of $ 6.25
+Added: per warrant share, are fully vested upon issuance, have a cashless exercise feature and are exercisable immediately.
+Added: Black-Scholes-Merton option pricing model, the Company determined the aggregate fair value of these Placement Agent Warrants to be
+Added: approximately $ 3,151,000
+Added: and comprises the non-cash equity issuance costs as presented on the
+Added: Consolidated Statements of Cash Flows of $34,477,000.
+Added: Effective August 23, 2021, the Company issued
+Added: Pre-funded Warrants pursuant to the Registered Direct Offering to purchase 5,570,000
+Added: shares of common stock in the amount of approximately $ 27,844,000
+Added: which required payments upon issuance of $4.999 per warrant share.
+Added: The Pre-funded Warrants have an exercise price of $ 0.001
+Added: per share, are fully vested upon issuance, are immediately exercisable, have a cashless exercise feature and do not have an expiration
+Added: As of April 30, 2022, 4,620,000
+Added: of the Pre-funded Warrants have been exercised for aggregate gross proceeds of $ 4,620,
+Added: which resulted in the issuance of 4,620,000 shares.
+Added: As of April 30, 2022, the remaining unexercised Pre-funded Warrants were 950,000
+Added: shares that can be exercised for $950.
+Added: The Company received $4,749,050 pursuant to the issuance of the Pre-funded Warrants and these
+Added: shares remain unissued as of April 30, 2022, (see Note 13 – Subsequent Events).
+Added: In August 2021, the Company received
+Added: twenty-seven cash exercise notices relating to the Common Warrants with respect to the First Offering totaling 2,522,387 warrant shares.
+Added: The Company received approximately $ 10,720,000 and issued 2,522,387 shares of common stock as a result of the exercise notices.
+Added: Series A Warrants and Placement Agent Warrants
+Added: were issued pursuant to the Securities Purchase Agreement dated as of August 19, 2021.
+Added: At the time, the Series A Warrants and the Placement
+Added: Agent Warrants were issued, neither the Series A Warrants, the Placement Agent Warrants nor the underlying common stock was registered
+Added: pursuant to the Securities Act.
+Added: The Company registered the common stock underlying the Series A Warrants and the Placement Agent Warrants
+Added: pursuant to a Registration Statement on Form S-3 (“Registration Statement”) filed with the Commission on November 8, 2021.
+Added: The Registration Statement became effective on November 17, 2021.
+Added: A summary of the Company’s warrant activity
and related information for the two years ended April 30, 2022, are shown below:
+Added: Schedule of warrant activity
Exercise Price
1 unchanged sentence
Outstanding, April 30, 2021
+Added: ( 8,041,414 )
Outstanding, April 30, 2022
2 unchanged sentences
concerning warrants outstanding and exercisable at April 30, 2022:
+Added: Schedule of warrants outstanding and exercisable
Exercise Prices
3 unchanged sentences
Exercise Price Per Share
−Removed: NOTE 7 –
−Removed: LEGAL PROCEEDINGS
+Added: NOTE 7 – LEGAL PROCEEDINGS
The Company is not currently a party to any pending
1 unchanged sentence
There are no legal proceedings to which any property of the Company is subject.
−Removed: NOTE 8 –
−Removed: RELATED PARTY TRANSACTIONS
+Added: NOTE 8 – RELATED PARTY TRANSACTIONS
The Company had the following related party transactions
10 unchanged sentences
Vin-de-Bona is owned by Prof.
−Removed: Günzburg and Dr.
−Removed: Salmons, both of whom are involved in numerous aspects of the Company’s scientific endeavors relating to cancer
+Added: Günzburg and Dr.
+Added: Salmons, both of whom are involved in numerous aspects of the Company’s scientific endeavors relating to cancer
and diabetes (Prof.
3 unchanged sentences
After the initial term, either party
−Removed: can terminate the agreement by giving the other party 30 days’
−Removed: written notice before the effective date of termination.
+Added: can terminate the agreement by giving the other party 30 days’ written notice before the effective date of termination.
The agreement
has been automatically renewed annually.
−Removed: The amounts incurred for the years ended April 30, 2021 and 2020 were approximately $82,000 and
−Removed: $24,000, respectively.
−Removed: In addition, during the years ended April 30, 2021 and 2020 the Company issued 167 and 167 shares of common stock,
−Removed: respectively, to Dr.
+Added: The amounts incurred for the years ended April 30, 2022, and 2021, were approximately $ 114,000
+Added: and $ 82,000 , respectively.
+Added: In addition, during the years ended April 30, 2022, and 2021, the Company issued 167 and 167 shares of common
+Added: stock, respectively, to Dr.
The Company recorded a noncash consulting expense of approximately $ 400 and $ 5,000 relating to these
share issuances for the years ended April 30, 2021 and 2020, respectively.
−Removed: During the year ended April 30, 2020, the Company
−Removed: issued one share of Series A Preferred Stock to the Chief Executive Officer of the Company for $1 pursuant to a subscription agreement.
−Removed: The Series A Preferred Stock is described in detail in Note 12 –
−Removed: Preferred Stock.
−Removed: The Board exercised its right to have the Company
−Removed: redeem the one share of Series A Preferred Stock.
−Removed: It is no longer issued and outstanding.
−Removed: NOTE 9 –
−Removed: COMMITMENTS AND CONTINGENCIES
+Added: NOTE 9 – COMMITMENTS AND CONTINGENCIES
The Company acquires assets still in development
6 unchanged sentences
upon a percentage of the sales of the pharmaceutical products if regulatory approval for marketing is obtained.
−Removed: Effective September 1, 2017, the Company entered
−Removed: into a lease for its office space in California.
−Removed: The term of the lease is for 24 months and expired on August 31, 2019.
−Removed: the Company entered into an additional one-year lease for the Leased Premises, commencing upon the expiration of the term of the prior
+Added: In May 2019, the Company entered into a lease
+Added: for its office space in Laguna Hills, California for a one-year lease for the leased premises.
The term of the lease expired on August
On May 28, 2020, the Company entered into an additional
−Removed: six-month lease of the office space, commencing on September 1, 2020.
+Added: six-month lease of this office space, commencing on September 1, 2020.
The term of the new lease expired on February 28, 2021.
On May 24, 2021, the Company entered into an additional
−Removed: six-month lease of the office space, commencing on September 1, 2021 and which expires on February 28, 2022.
+Added: six-month lease of this office space, commencing on September 1, 2021, which expires on February 28, 2022.
+Added: In October 2021, the Company moved the Company’s
+Added: headquarter from Laguna Hills, California to Las Vegas.
+Added: In doing so, the Company entered into a lease for office space in Las
+Added: Vegas, Nevada.
+Added: The term of the lease expires on April 30, 2022.
+Added: In January 2022, the Company entered into an additional
+Added: six-month lease of the Las Vegas, Nevada office space, commencing on May 1, 2022, which expires on October 31, 2022.
Rent expenses for these offices for the years
ended April 30, 2022, and 2021, were $ 19,341 and $ 20,429 , respectively.
−Removed: The following table summarizes the Company’s
+Added: The following table summarizes the Company’s
aggregate future minimum lease payments required under the operating lease as of:
−Removed: Years Ending April 30,
+Added: Schedule of future minimum lease payments
+Added: Year Ending April 30,
Material Agreements
−Removed: The Company’s material agreements are identified
−Removed: and summarized in Note 1 –
−Removed: Nature of Business –
−Removed: Company Background.
+Added: The Company’s material agreements are identified
+Added: and summarized in Note 1 – Nature of Business – Company Background.
Compensation Agreements
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member in April 2015 which continued in effect until amended in May 2017.
+Added: The Company entered into amended and restated
+Added: executive compensation agreements with two executive officers with an effective date of January 1, 2022 (“Amendment Date”).
+Added: Each agreement has a term of three (3) years from the Amendment Date (“Initial Term”) and has automatic renewals of one (1)
+Added: year (“Renewal Term”) unless the Company or the officer provides written notice of termination at least ninety (90) days prior
+Added: to the end of the Initial Term or the Renewal Term.
In May 2017, the Company amended the compensation
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(ii) 333 fully paid, non-assessable
−Removed: shares of the Company’s restricted common stock (“Shares”) annually;
+Added: shares of the Company’s restricted common stock (“Shares”) annually;
and (iii) a five-year option to purchase 333 Shares
3 unchanged sentences
NOTE 10 - INCOME TAXES
−Removed: At April 30, 2021, the Company had federal and
−Removed: state net operating loss carryforwards of approximately $47,902,000 and $44,165,000, respectively, available to offset against future
−Removed: taxable income;
+Added: At April 30, 2022, the Company had federal
+Added: and state net operating loss carryforwards of approximately $ 52,382,000
+Added: and $ 48,619,000 ,
+Added: respectively, available to offset against future taxable income;
these operating loss carryforwards expire in 2021 through 2038.
+Added: Internal Revenue Code section 382 imposes an annual limitation for the utilization of tax attributes if there is an “ownership
+Added: changes.” Based upon the equity activity during the year ended April 30, 2022, the Company had an ownership change in August
+Added: Accordingly, it is more likely than not that section 382 will impose a restrictive limitation on the utilization of the
+Added: Company’s federal tax attributes and would require the net operating loss carryforward to be written down.
+Added: The Company is
+Added: currently working through its section 382 study.
Current tax laws limit the amount of loss available
2 unchanged sentences
taxable income may be limited.
−Removed: Based on the assessment of all available evidence including, but not limited to, the Company’s limited
+Added: Based on the assessment of all available evidence including, but not limited to, the Company’s limited
operating history in its core business and lack of profitability, uncertainties of the commercial viability of its technology, the impact
5 unchanged sentences
between the financial reporting carrying amounts of assets and liabilities and income tax carrying amounts of assets and liabilities.
−Removed: The components of the Company’s deferred tax assets and liabilities are as follows:
+Added: The components of the Company’s deferred tax assets and liabilities are as follows:
+Added: Schedule of deferred tax assets and liabilities
Deferred tax assets:
5 unchanged sentences
( 16,498,199 )
+Added: Net deferred tax assets
For all years presented, the Company did not recognize
any deferred tax assets or liabilities.
−Removed: The net change in valuation allowance for the years ended April 30, 2021 and 2020 were increases
−Removed: of $969,241 and $1,341,187, respectively.
+Added: The net change in valuation allowance for the years ended April 30, 2022, and 2021, was a decrease
+Added: of $ 739,798 and an increase of $ 969,241 , respectively.
The provision for income taxes differs from the
provision computed by applying the Federal statutory rate to net loss before income taxes as follows:
+Added: Schedule of provision for income taxes
Years Ended April 30,
Federal benefit at statutory rate
+Added: $ ( 890,224 )
State income taxes, net of Federal taxes
1 unchanged sentence
Provision related to change in valuation allowance
+Added: Expired stock options
Net valuation allowance for state tax deductions
−Removed: There have been no changes to the Company’s
+Added: Provision for income taxes
+Added: There have been no changes to the Company’s
liability for unrecognized tax benefits during the year ended April 30, 2022.
3 unchanged sentences
remain open to examination by the Internal Revenue Service and various state tax authorities.
−Removed: The Company’s policy is to recognize any
+Added: The Company’s policy is to recognize any
interest and penalties related to unrecognized tax benefits as a component of income tax expense.
1 unchanged sentence
and 2021, the Company had accrued no interest or penalties related to uncertain tax positions.
−Removed: NOTE 11 –
−Removed: EARNINGS PER SHARE
+Added: NOTE 11 – EARNINGS PER SHARE
Basic earnings (loss) per share is computed by
10 unchanged sentences
share calculations:
+Added: Earnings per share calculations
Years Ended April 30,
−Removed: $ (3,551,236 )
−Removed: $ (3,826,888 )
Basic weighted average number of shares outstanding
1 unchanged sentence
Basic and diluted loss per share
−Removed: The table below sets forth these potentially dilutive
+Added: The table below sets forth these potentially
+Added: dilutive securities:
+Added: Schedule of potentially dilutive securities
Years Ended April 30,
2 unchanged sentences
Total excluded options and warrants
−Removed: NOTE 12 –
−Removed: PREFERRED STOCK
−Removed: The Company has authorized 10,000,000 shares
−Removed: of preferred stock, with a par value of $0.0001, of which one share has been designated as "Series A Preferred Stock".
−Removed: share of Series A Preferred Stock was issued on October 30, 2019 and repurchased by the Company on December 3, 2019.
−Removed: As of April 30, 2021,
+Added: NOTE 12 – PREFERRED STOCK
+Added: The Company has authorized 10,000,000 shares of
+Added: preferred stock, with a par value of $ 0.0001 , of which one share has been designated as "Series A Preferred Stock".
30, 2022, there are no shares of preferred stock issued and outstanding.
The description of the Series A Preferred Stock
−Removed: below is qualified in its entirety by reference to the Company’s Articles of Incorporation, as amended.
+Added: below is qualified in its entirety by reference to the Company’s Articles of Incorporation, as amended.
The Series A Preferred Stock has the following
4 unchanged sentences
The Series A Preferred Stock has no rights of transfer, conversion, dividends, preferences upon liquidation or participation in any distributions to shareholders.
−Removed: NOTE 13 –
−Removed: SUBSEQUENT EVENTS
−Removed: On May 24, 2021, the Company entered into a six-month
−Removed: office lease extension commencing on September 1, 2021.
−Removed: The lease extension is for the office where the Company is currently located in
−Removed: Laguna Hills, California.
−Removed: The term of the new lease expires on February 28, 2022 and requires monthly lease payments of approximately
−Removed: Effective June 30, 2021, the Company increased
−Removed: the authorized shares of common stock to 50 billion shares or 33,333,334 shares after the reverse stock split.
−Removed: The Company filed a Certificate
−Removed: of Amendment to the Articles of Incorporation with the Nevada Secretary of State.
−Removed: Effective June 30, 2021, the Company implemented
−Removed: the 2021 Equity Incentive Plan as approved by the Company’s stockholders.
−Removed: Effective July 12, 2021, the Company filed a Certificate
−Removed: of Change with the Nevada Secretary of State that authorized a 1-for-1,500 reverse stock split.
−Removed: The reverse resulted in the Company reducing
−Removed: the authorized number of shares of common stock to 33,333,334.
−Removed: On August 9, 2021, the Company entered into an
−Removed: underwriting agreement with H.C.
−Removed: Wainwright & Co., LLC with respect to a public offering of 2,630,385 shares of common stock, 899,027
−Removed: prefunded warrants and 3,529,412 accompanying common warrants.
−Removed: The total gross proceeds of the offering before deduction of underwriting
−Removed: discounts, commissions and estimated offering expenses payable by the Company are expected to be $15 million.
−Removed: In such offering, the Company granted the underwriter
−Removed: an option for a period of 30 days commencing on August 9, 2021 to purchase additional shares of its common stock and/or accompanying warrants.
−Removed: If the underwriter exercises such option in full, the total gross proceeds of the offering before deduction of underwriting discounts,
−Removed: commissions and estimated offering expenses payable by the Company are expected to be $17,249,998.
+Added: NOTE 13 – SUBSEQUENT EVENTS
+Added: In May 2022, the Board granted the Company’s
+Added: Chief Executive Officer and Chief Financial Officer stock options of 529,000 and 201,860, respectively, and restricted stock units of
+Added: 150,800 and 57,540, respectively.
+Added: These grants were made subject to an increase in the Company’s authorized shares of common stock.
+Added: The Company is planning to increase the authorized shares of common stock at its 2022 annual shareholders meeting.
+Added: In May 2022, the Board of Directors authorized
+Added: a Share Repurchase Program whereby the Company would repurchase the Company’s common stock at the discretion of the Company’s
+Added: Chief Executive Officer, depending on market conditions over a two-year period, in the amount of up to $10 million.
+Added: The repurchases shall
+Added: follow the applicable laws, including the Nevada Revised Statutes and Federal securities laws and in a manner to comply with the provisions
+Added: of Rule 10b-18 under the Securities Act or any subsequent superseding or amending rule.
+Added: As of July 28, 2022, there has been 851,981 shares
+Added: of the Company’s common stock repurchased at an approximate cost of $2,091,000, including commissions.
+Added: On July 7, 2022, the Company received a notice
+Added: of exercise relating to the Pre-funded Warrants pursuant to the registered direct offering in the amount of $880 which resulted in the
+Added: issuance of 880,000 shares of common stock.
PHARMACYTE BIOTECH, INC.
−Removed: SCHEDULE II —
−Removed: VALUATION AND QUALIFYING
+Added: SCHEDULE II — VALUATION AND QUALIFYING
Years Ended April 30, 2022 and 2021
+Added: Schedule of valuation and qualifying accounts
Reserve Deducted in the Balance Sheets from the Asset to which it applies:
3 unchanged sentences
Compared sentence by sentence after normalising whitespace, quotation marks, case and digits, so re-formatting and restated figures do not read as changed language. Wording changes appear as one removal and one addition. The current filing and the prior one are authoritative.