22 unchanged sentences
Opinion on Internal Control over Financial Reporting
−Removed: We have audited Kymera Therapeutics, Inc.
−Removed: internal control over financial reporting as of December 31, 2024, based on criteria established in Internal Control—Integrated Framework issued by the Committee of Sponsoring Organizations of the Treadway Commission (2013 framework) (the COSO criteria).
−Removed: In our opinion, Kymera Therapeutics, Inc (the Company) maintained, in all material respects, effective internal control over financial reporting as of December 31, 2024, based on the COSO criteria.
+Added: We have audited Kymera Therapeutics, Inc.’s internal control over financial reporting as of December 31, 2025, based on criteria established in Internal Control—Integrated Framework issued by the Committee of Sponsoring Organizations of the Treadway Commission (2013 framework) (the COSO criteria).
+Added: In our opinion, Kymera Therapeutics, Inc.
+Added: (the Company) maintained, in all material respects, effective internal control over financial reporting as of December 31, 2025, based on the COSO criteria.
We also have audited, in accordance with the standards of the Public Company Accounting Oversight Board (United States) (PCAOB), the consolidated balance sheets of the Company as of December 31, 2025 and 2024, the related consolidated statements of operations and comprehensive loss, stockholders’ equity and cash flows for each of the three years in the period ended December 31, 2025, and the related notes and our report dated February 26, 2026 expressed an unqualified opinion thereon.
28 unchanged sentences
Description of Trading Arrangement
+Added: Jeremy Chadwick
+Added: Chief Operating Officer
+Added: Trading plan intended to satisfy the affirmative defense conditions of Securities Exchange Act Rule 10b5- 1 (c)
+Added: ( December 10, 2025 )
+Added: December 31, 2026
+Added: Exercises of vested stock options and sales of shares of our common stock pursuant to the terms of the trading plan
+Added: Chief Business Officer
+Added: Trading plan intended to satisfy the affirmative defense conditions of Securities Exchange Act Rule 10b5- 1 (c)
+Added: ( December 10, 2025 )
+Added: December 10, 2026
+Added: Exercises of vested stock options and sales of shares of our common stock pursuant to the terms of the trading plan
Elena Ridloff
Trading plan intended to satisfy the affirmative defense conditions of Securities Exchange Act Rule 10b5- 1 (c)
−Removed: ( November 25, 2024 )
( December 11, 2025 )
+Added: December 31, 2026
Exercises of vested stock options and sales of shares of our common stock pursuant to the terms of the trading plan
+Added: Trading plan intended to satisfy the affirmative defense conditions of Securities Exchange Act Rule 10b5- 1 (c)
+Added: ( December 16, 2025 )
+Added: September 16, 2026
+Added: Exercises of vested stock options and sales of shares of our common stock pursuant to the terms of the trading plan
+Added: 1 - These shares reflect the aggregate maximum number of Restricted Stock Units (“RSU”) prior to any non-discretionary sell-to-cover transactions in addition to other shares eligible to be sold pursuant to the plan.
+Added: The Company has a non-discretionary sell-to-cover requirement to satisfy tax withholding obligations associated with RSU vesting for employees.
Disclosure Regarding Foreign Jurisdictions that Prevent Inspections.
20 unchanged sentences
333-240264) filed with the Securities and Exchange Commission on August 17, 2020).
−Removed: Second Amended and Restated Investors’ Rights Agreement among the Registrant and certain of its stockholders, effective as of March 11, 2020 (Incorporated by reference to Exhibit 4.2 to the Registrant’s Registration Statement on Form S-1 (File No.
−Removed: 333-240264) filed with the Securities and Exchange Commission on July 31, 2020).
+Added: Registration Rights Agreement by and among the Registrant and certain of its stockholders dated June 26, 2025 (Incorporated by reference to Exhibit 10.1 to the Registrant's Current Report on Form 8-K (File No.
+Added: 001-39460) filed with the Securities and Exchange Commission on June 27,2025).
Description of Securities (Incorporated by reference to Exhibit 4.3 to the Registrant’s Annual Report on Form 10-K (File No.
4 unchanged sentences
Form of Pre-Funded Warrant (Incorporated by reference to Exhibit 4.1 to the Registrant’s Current Report on Form 8-K filed with the Securities and Exchange Commission on August 20, 2024).
+Added: Form of Pre-Funded Warrant (Incorporated by reference to Exhibit 4.1 to the Registrant’s Current Report on Form 8-K filed with the Securities and Exchange Commission on June 27, 2025).
2018 Stock Option and Grant Plan, and form of award agreements thereunder (Incorporated by reference to Exhibit 10.1 to the Registrant’s Registration Statement on Form S-1 (File No.
4 unchanged sentences
001-39460) filed with the Securities and Exchange Commission on June 20, 2024).
+Added: Amended and Restated Non-Employee Director Compensation Policy dated June 25, 2025 (Incorporated by reference to Exhibit 10.3 to the Registrant’s Quarterly Report on Form 10-Q (File No.
+Added: 001-39460) filed with the Securities and Exchange Commission on August 11, 2025).
Amended and Restated Non-Employee Director Compensation Policy dated March 27, 2024 (Incorporated by reference to Exhibit 10.1 to the Registrant’s Quarterly Report on Form 10-Q (File No.
43 unchanged sentences
+ This certification will not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liability of that section.
−Removed: Such certification will not be deemed to be incorporated by reference into
−Removed: any filing under the Securities Act of 1933, as amended, except to the extent specifically incorporated by reference into such filing.
+Added: Such certification will not be deemed to be incorporated by reference into any filing under the Securities Act of 1933, as amended, except to the extent specifically incorporated by reference into such filing.
# Indicates a management contract or any compensatory plan, contract or arrangement.
43 unchanged sentences
Maraganore, PhD
−Removed: /s/ Leigh Morgan
−Removed: February 27, 2025
/s/ Elena, Ridloff, CFA
1 unchanged sentence
Elena Ridloff, CFA
−Removed: /s/ Victor Sandor
+Added: /s/ Victor Sandor, MDCM
February 26, 2026
1 unchanged sentence
Compared sentence by sentence after normalising whitespace, quotation marks, case and digits, so re-formatting and restated figures do not read as changed language. Wording changes appear as one removal and one addition. The current filing and the prior one are authoritative.