ITEM 2 - PROPERTIES
−Removed: We lease real property to support our business, including manufacturing, research and development, sales, marketing and administration.
+Added: We lease real property throughout the world to support our business, including manufacturing, research and development, sales, marketing and administration.
We believe our facilities are suitable and adequate for our current and near-term needs, and that we will be able to locate additional facilities as needed.
−Removed: The following table sets forth the locations of our manufacturing facilities:
−Removed: Location Lease Expiration Dates
−Removed: San Diego, California 2028 (1)
−Removed: Mesa, Arizona 2030 (2)
−Removed: Penang, Malaysia 2082 (3)
+Added: The following table sets forth the locations of our corporate headquarters and manufacturing facilities:
+Added: Location Purpose
+Added: San Diego, California Corporate headquarters, research and development, and manufacturing
+Added: Mesa, Arizona Manufacturing
+Added: Penang, Malaysia Manufacturing
Athenry, Ireland (1)
−Removed: (1) Excludes a renewal that would be at our option to extend the term of a lease expiring in 2028 for one additional three to five-year term.
−Removed: (2) Excludes renewals that would be at our option to extend the term of a lease expiring in 2028 for four additional five-year terms and also excludes renewals that would be at our option to extend the term of a lease expiring in 2030 for two additional five-year terms.
−Removed: (3) Represents 60-year land leases with the state authority expiring at varying dates through 2082.
−Removed: (4) Represents a 999-year land lease with the Industrial Development Agency of Ireland.
−Removed: Our headquarters, research and development, and certain of our manufacturing operations are located in San Diego, California.
−Removed: In addition, the construction of a new manufacturing facility in Athenry, Ireland is underway.
−Removed: We also lease various manufacturing, administrative, warehouse and customer support real properties throughout the world.
+Added: Manufacturing
+Added: (1) Our new manufacturing facility in Athenry, Ireland is under construction.
As of December 31, 2025, we had approximately 79,700 square feet of laboratory space and approximately 159,600 square feet of controlled environment rooms.
+Added: See Note 5 “ Leases and Other Commitments ” to the consolidated financial statements in Part II, Item 8 of this Annual Report for more information.
Compared sentence by sentence after normalising whitespace, quotation marks, case and digits, so re-formatting and restated figures do not read as changed language. Wording changes appear as one removal and one addition. The current filing and the prior one are authoritative.