18 unchanged sentences
(the Company) maintained, in all material respects, effective internal control over financial reporting as of December 31, 2023, based on the COSO criteria.
−Removed: We also have audited, in accordance with the standards of the Public Company Accounting Oversight Board (United States) (PCAOB), the consolidated balance sheets of the Company as of December 31, 2022 and 2021, the related consolidated statements of operations and comprehensive income (loss), stockholders’ equity and cash flows for each of the three years in the period ended December 31, 2022, and the related notes and our report dated February 27, 2023 expressed an unqualified opinion thereon.
+Added: We also have audited, in accordance with the standards of the Public Company Accounting Oversight Board (United States) (PCAOB), the consolidated balance sheets of the Company as of December 31, 2023 and 2022, the related consolidated statements of operations and comprehensive loss, stockholders’ equity and cash flows for each of the three years in the period ended December 31, 2023, and the related notes and our report dated February 27, 2024 expressed an unqualified opinion thereon.
Basis for Opinion
18 unchanged sentences
OTHER INFORMATION
+Added: Securities Trading Plans of Directors and Executive Officers
+Added: Our policy governing transactions in our securities by our directors, officers, and employees permits our officers, directors and employees to enter into trading plans complying with Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.
+Added: As disclosed in the table below, during the fourth quarter of 2023, certain of our directors adopted a “Rule 10b5-1 trading arrangement”.
+Added: This plan provides for the sale of our common stock and is intended to satisfy the affirmative defense in Rule 10b5-1(c).
+Added: Name Position Date of Plan Adoption Scheduled End Date of Trading Arrangement (1)
+Added: Maximum Total Shares of Common Stock to be Sold Under the Plan (2)
+Added: Steve Krognes
+Added: 12/1/2023 3/1/2025 282,500
+Added: __________________________________________________
+Added: (1) The trading arrangement may expire on an earlier date if and when all transactions under the arrangement are completed.
+Added: (2) This amounts represents the maximum total shares that could be sold under the plan, but the amounts may change for executive officers due to the sale of shares to satisfy tax withholding requirements.
+Added: No other officers or directors, as defined in Rule 16a-1(f), adopted and/or terminated of a “Rule 10b5-1 trading arrangement” or a “non-Rule 10b5-1 trading arrangement,” as defined in Regulation S-K Item 408, during the fourth quarter ended December 31, 2023.
DISCLOSURE REGARDING FOREIGN JURISDICTIONS THAT PREVENT INSPECTIONS
25 unchanged sentences
8-K 001-38311 3.2 12/12/2017
−Removed: 4.1 Investors’ Rights Agreement among the Registrant and certain of its stockholders, dated May 8, 2015, as amended on June 4, 2015, July 22, 2015 and June 22, 2016.
−Removed: S-1 333-221522 4.1 11/13/2017
4.1 Specimen Common Stock Certificate of the Registrant.
2 unchanged sentences
S-3ASR 333-263107 4.3 2/28/2022
+Added: 4.3 Form of Pre-Funded Warrant
+Added: 001-38311 4.1
4.4 Description of the Registrant’s Common Stock.
45 unchanged sentences
7 to Development and Manufacturing Services Agreement between the Registrant and Lonza Sales AG, dated March 29, 2021.
−Removed: — — — Filed herewith
+Added: 10-K 001-38311 10.12.7
10.12.8# Amendment No.
8 to Development and Manufacturing Services Agreement between the Registrant and Lonza Sales AG, dated September 8, 2022.
−Removed: — — — Filed herewith
+Added: 10-K 001-38311 10.12.8
10.12.9 Amendment No.
9 to Development and Manufacturing Services Agreement between the Registrant and Lonza Sales AG, dated December 7, 2022.
−Removed: — — — Filed herewith
+Added: 10-K 001-38311 10.12.9
10.13+ Amended and Restated Key Executive Change in Control and Severance Plan.
35 unchanged sentences
S-3ASR 333-263107 1.2 2/28/2022
+Added: Amendment to Definitive LRRK2 Agreement and Waiver of and Amendment to Right of First Negotiation, Option, and License Agreement.
+Added: 10-Q 001-38311 10.1 11/7/2023
+Added: 10.32 S ecurities Purchase Agreement , dated February 27, 2024 , by and among the Company and the Purchasers named therein
+Added: 001-38311 10.1 2/27/24
+Added: 10.33 Nominating Agreement by and among the Company and Investor
+Added: 001-38311 10.2
+Added: 10.34 Compensation Recovery Policy (“Clawback Policy”)
+Added: — — — Filed herewith
+Added: 10.35 Denali Insider Trading Policy and Guidelines with Respect to Certain Transactions in Securities as amended through March 31, 2023
+Added: — — — Filed herewith
21.1 Subsidiaries of the Registrant.
11 unchanged sentences
101 The following materials from the Company’s Annual Report on Form 10-K for the year ended December 31, 2023, formatted in Inline XBRL:
−Removed: (i) Consolidated Balance Sheets, (ii) Consolidated Statements of Operations and Comprehensive Income (Loss), (iii) Consolidated Statements of Cash Flows (iv) Consolidated Statements of Stockholders’ Equity and (v) Notes to Consolidated Financial Statements.
+Added: (i) Consolidated Balance Sheets, (ii) Consolidated Statements of Operations and Comprehensive Loss, (iii) Consolidated Statements of Cash Flows (iv) Consolidated Statements of Stockholders’ Equity and (v) Notes to Consolidated Financial Statements.
— — — Filed herewith
26 unchanged sentences
Vicki Sato, Ph.D.
−Removed: /s/ Douglas Cole
−Removed: Director February 27, 2023
−Removed: Douglas Cole, M.D.
/s/ Jennifer Cook Director February 27, 2024
14 unchanged sentences
Compared sentence by sentence after normalising whitespace, quotation marks, case and digits, so re-formatting and restated figures do not read as changed language. Wording changes appear as one removal and one addition. The current filing and the prior one are authoritative.