AMGEN INC 10-K

Item 2. PROPERTIES As of December 31, 2022, we owned or leased approximately 150 properties. The locations and primary functions of significant properties are summarized in the following tables: U.S. Location: Manufacturing Administrative R&D Sales & marketing Warehouse Distribution center Thousand Oaks, CA* P P P P P P San Francisco, CA P Louisville, KY P P Cambridge, MA P Juncos, Puerto Rico P P P P West Greenwich, RI P P P Tampa, FL P Other U.S. cities P P * Corporate headquarters ROW Location: Manufacturing Administrative R&D Sales & marketing Warehouse Distribution center Brazil P P P P P Canada P P P China P P Denmark P P P Germany P P P Iceland P P Ireland P P P P P Japan P P Netherlands P P P P P Singapore P P P P Switzerland P P United Kingdom P P P Other countries P P P P Excluded from the information above are (i) undeveloped land and leased properties that have been abandoned and (ii) certain buildings we still own but that are no longer used in our business. There are no material encumbrances on our owned properties. We believe our facilities are suitable for their intended uses and, in conjunction with our third-party contract manufacturing agreements, provide adequate capacity and are sufficient to meet our expected needs. See Item 1A. Risk Factors for a discussion of the factors that could adversely impact our manufacturing operations and the global supply of our products. See Item 1. Business—Manufacturing, Distribution and Raw Materials. Item 3. LEGAL PROCEEDINGS Certain of the legal proceedings in which we are involved are discussed in Part IV—Note 19, Contingencies and commitments, to the Consolidated Financial Statements and are hereby incorporated by reference. Item 4. MINE SAFETY DISCLOSURES Not applicable. 52 PART II