1 unchanged sentence
Zug, Switzerland;
−Removed: and Maidenhead, UK.
+Added: Maidenhead, United Kingdom;
+Added: and Tokyo, Japan.
A description of certain of the facilities we lease or own as of January 31, 2021 is included in the table below.
2 unchanged sentences
Expiration Date Renewal Option
−Removed: 675 West Kendall Street Cambridge, Massachusetts Corporate headquarters and primary research facility 295,000 January 2034 Two five-year terms
+Added: 675 West Kendall Street Henri A.
+Added: Termeer Square Cambridge, Massachusetts Corporate headquarters and primary research facility 295,000 January 2034 Two five-year terms
300 Third Street
1 unchanged sentence
101 Main Street
−Removed: Cambridge, Massachusetts Office space 72,000 June 2021 and March 2024 One five-year term on each lease
+Added: Cambridge, Massachusetts Office space* 72,000 March 2024 and June 2026 One five-year term on each lease
20 Commerce Way
3 unchanged sentences
Grafenauweg 4
−Removed: 6300 Zug International headquarters 14,500 March 2023 One five-year term
+Added: 6300 Zug, Switzerland International headquarters 14,500 March 2023 One five-year term
Braywick Gate
3 unchanged sentences
Amsterdam, Netherlands Office space 12,500 April 2025 One five-year term
+Added: Pacific Century Place
+Added: 1-Chome-11-1 Marunouchi Chiyoda-ku
+Added: Tokyo, Japan Office space 16,900 May 2025 None
__________ _______________________________
−Removed: * We are completing construction of a manufacturing facility at this site for drug substance for clinical and eventually commercial use.
+Added: * We lease office space located on the 12th, 13th and 16th floors at 101 Main Street, Cambridge, Massachusetts under a non-cancelable real property lease agreement by and between the Company and RREEF America REIT II CORP.
+Added: PPP, dated as of April 15, 2015, or Lease.
+Added: On September 30, 2020, we entered into a First Amendment to Lease, pursuant to which the term of the Lease with respect to the 12th and 13th floors was extended for an additional five years, through June 30, 2026.
+Added: The term of the Lease, as amended, shall expire and be terminated solely as to the 16th floor on June 30, 2021.
+Added: In addition, we have a separate lease agreement for the 10th floor at 101 Main Street, which expires in March 2024.
** We manufacture ONPATTRO (patisiran) formulated bulk drug product at this location.
−Removed: *** We executed a lease for a new office space in Amsterdam in the fourth quarter of 2019.
−Removed: The lease commencement date is March 1, 2020.
In addition to the locations above, we also occupy small offices in multiple locations in and outside of the U.S.
3 unchanged sentences
Compared sentence by sentence after normalising whitespace, quotation marks, case and digits, so re-formatting and restated figures do not read as changed language. Wording changes appear as one removal and one addition. The current filing and the prior one are authoritative.