3 unchanged sentences
“Risk Factors” of our Annual Report on Form 10-K for the fiscal year ended December 31, 2021, filed with the Securities and Exchange Commission on March 31, 2022.
−Removed: Other than as described below, t here have been no material changes to the risk factors described in that report.
−Removed: Our existing indebtedness contains restrictions that potentially limit our flexibility in operating our business.
−Removed: In addition, we may be required to make a prepayment or repay our outstanding indebtedness earlier than we expect.
−Removed: On August 12, 2021, we entered into a Loan and Security Agreement, or the Term Loan Agreement, with the lenders party thereto from time to time, or the Lenders, and Silicon Valley Bank, as administrative agent and collateral agent for the Lenders, or the Agent, which provides for term loans of up to $100.0 million in the aggregate available in four tranches.
−Removed: The Term Loan Agreement contains various covenants that limit our ability to engage in specified types of transactions.
−Removed: These covenants limit our ability to, among other things:
−Removed: incur or assume certain debt;
−Removed: merge or consolidate or acquire all or substantially all of the capital stock or property of another entity;
−Removed: change the nature of our business;
−Removed: change our organizational structure or type;
−Removed: license, transfer, or dispose of certain assets;
−Removed: grant certain types of liens on our assets;
−Removed: make certain investments;
−Removed: pay cash dividends;
−Removed: enter into material transactions with affiliates.
−Removed: A breach of any of these covenants could result in an event of default under the Term Loan Agreement.
−Removed: An event of default will also occur if, among other things, a material adverse change in our business, operations, or condition occurs, which could potentially include a material impairment of the prospect of our repayment of any portion of the amounts we owe under the Term Loan Agreement.
−Removed: In the case of a continuing event of default under the Term Loan Agreement, the lenders could elect to declare all amounts outstanding to be immediately due and payable, proceed against the collateral in which we granted the Lenders a security interest under the Term Loan Agreement, or otherwise exercise the rights of a secured creditor.
−Removed: Amounts outstanding under the Term Loan Agreement are secured by all of our existing and future assets, excluding intellectual property, which is subject to a negative pledge arrangement.
−Removed: At closing, we drew on $30.0 million of the $40.0 million available to us as part of the first tranche.
−Removed: The Term Loan Agreement also gives us the ability to access an additional $60.0 million at our option, of which $40.0 million may be drawn in two additional tranches subject to the achievement of certain specified conditions and of which $20.0 million may be drawn in an additional tranche with the approval of the Agent and the Lenders.
−Removed: If we are unable to satisfy these or other required conditions, or if the Agent and Lenders do not consent, as applicable, we would not be able to draw down the remaining tranches of financing and may not be able to obtain alternative financing on commercially reasonable terms or at all, which could adversely impact our business.
−Removed: We may not have enough available cash to repay or refinance our indebtedness at the time any such repayment is required.
−Removed: In such an event, we may be required to delay, limit, reduce, or terminate our preclinical and clinical product development or commercialization efforts or build out of our cGMP manufacturing facility or grant others rights to develop and market product
−Removed: candidates that we would otherwise prefer to develop and market ourselves.
−Removed: Our business, financial condition, and results of operations could be materially adversely affected as a result.
+Added: Other than as described below, there have been no material changes to the risk factors described in that report.
+Added: Unfavorable global economic conditions could adversely affect our business, financial condition or results of operations.
+Added: Our results of operations could be adversely affected by general conditions in the global economy and in the global financial markets.
+Added: For example, the COVID-19 pandemic has caused extreme volatility and disruptions in the capital and credit markets.
+Added: In addition, Russia’s invasion of Ukraine may lead to a prolonged, adverse impact on global economic, social and market conditions.
+Added: A severe or prolonged economic downturn could result in a variety of risks to our business, including weakened demand for our product candidates and our ability to raise additional capital when needed on acceptable terms, if at all.
+Added: A weak or declining economy could also strain our suppliers, possibly resulting in supply disruption, or cause delays in payments for our services by third-party payors or our collaborators.
+Added: For example, while we do not have any current operations in Ukraine or Russia, we do not know the extent to which Russia’s invasion of Ukraine could impact any of our current suppliers and their ability to provide us with supplies and services.
+Added: Any of the foregoing could harm our business and we cannot anticipate all of the ways in which the current economic climate and financial market conditions could adversely impact our business, financial condition, results of operations and prospects.
Compared sentence by sentence after normalising whitespace, quotation marks, case and digits, so re-formatting and restated figures do not read as changed language. Wording changes appear as one removal and one addition. The current filing and the prior one are authoritative.