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We maintain “disclosure controls and procedures,” as defined in Rules 13a-15(e) and 15d-15(e) under the Exchange Act, that are designed to ensure that information required to be disclosed in the reports that we file or submit under the Exchange Act is recorded, processed, summarized and reported within the time periods specified in the SEC’s rules and forms and accumulated and communicated to our management, including our principal executive and principal financial officers, or persons performing similar functions, as appropriate to allow timely decisions regarding required disclosure.
−Removed: Our management, with the participation of our Chief Executive Officer (principal executive officer) and Vice-President, Strategy and Finance (principal financial officer), evaluated the effectiveness of our disclosure controls and procedures (as defined in the Securities Exchange Act of 1934 Rules 13a-15(e) or 15d-15(e)) as required by paragraph (b) of Exchange Act Rules 13a-15 or 15d-15, as of December 31, 2023.
−Removed: Based on the evaluation of our disclosure controls and procedures as of December 31, 2023, our Chief Executive Officer and Vice-President, Strategy and Finance concluded that, as of such date, our disclosure controls and procedures were effective.
+Added: Our management, with the participation of our Chief Executive Officer (principal executive officer) and Chief Financial Officer & Head of Corporate Strategy (principal financial officer), evaluated the effectiveness of our disclosure controls and procedures (as defined in the Securities Exchange Act of 1934 Rules 13a-15(e) or 15d-15(e)) as required by paragraph (b) of Exchange Act Rules 13a-15 or 15d-15, as of December 31, 2024.
+Added: Based on the evaluation of our disclosure controls and procedures as of December 31, 2024, our Chief Executive Officer and Chief Financial Officer & Head of Corporate Strategy concluded that, as of such date, our disclosure controls and procedures were effective.
Internal Control Over Financial Reporting
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Not applicable.
+Added: Certain information required by Part III is omitted from this report because we will file with the SEC a definitive proxy statement pursuant to Regulation 14A, (the “2025 Proxy Statement”), no later than 120 days after the end of our fiscal year, and certain information included therein is incorporated herein by reference.
DIRECTORS, EXECUTIVE OFFICERS AND CORPORATE GOVERNANCE
−Removed: Information About Our Directors
−Removed: Information regarding our Directors required by this item will be contained in our 2024 Proxy Statement under the caption “Information Regarding Director Nominees and Continuing Directors,” and is hereby incorporated by reference.
−Removed: Information About Our Executive Officers
−Removed: Information regarding our Executive Officers required by this item will be contained in our 2024 Proxy Statement under the caption “Executive Officers,” and is hereby incorporated by reference.
−Removed: Identification of Audit Committee and Financial Experts
−Removed: Information regarding our Audit Committee and Financial Experts required by this item will be contained in our 2024 Proxy Statement under the caption “Information Regarding the Board of Directors and Corporate Governance—Audit Committee,” and is hereby incorporated by reference.
−Removed: Material Changes to Procedures for Recommending Directors
−Removed: Information regarding our Procedures for Recommending Directors required by this item will be contained in our 2024 Proxy Statement under the caption “Information Regarding the Board of Directors and Corporate Governance—Nominating and Corporate Governance Committee,” and is hereby incorporated by reference.
+Added: Executive Officers and Directors
+Added: The information required by this item will be contained in our 2025 Proxy Statement, under the captions “Information Regarding Director Nominees and Continuing Directors,” “Information Regarding the Board of Directors and Corporate Governance,” “Executive Officers” and “Delinquent Section 16(a) Reports,” if applicable, and is incorporated in this report by reference.
Code of Business Conduct and Ethics
−Removed: Information regarding our Code of Business Conduct and Ethics (the “Code of Conduct”) required by this item will be contained in our 2024 Proxy Statement under the caption “Information Regarding the Board of Directors and Corporate Governance—Code of Ethics,” and is hereby incorporated by reference.
−Removed: If we make any substantive amendments to the Code of Conduct or grant any waiver from a provision of the Code of Conduct to any executive officer or director, we will promptly disclose the nature of the amendment or waiver on its website.
+Added: We have adopted a Code of Business Conduct that applies to all officers, directors and employees.
+Added: If we ever were to amend or waive any provision of our Code of Conduct that applies to our principal executive officer, principal financial officer, principal accounting officer or any person performing similar functions, we intend to promptly disclose on our website (i) the date and nature of any amendment (other than technical, administrative or other non-substantive amendments) to the Code of Conduct that relates to any element of the code of ethics definition enumerated in Item 406(b) of Regulation S-K and (ii) the nature of any waiver, including an implicit waiver, from a provision of the Code of Conduct that is granted to one of these specified individuals that relates to one or more of the elements of the code of ethics definition enumerated in Item 406(b) of Regulation S-K, the name of such person who is granted the waiver and the date of the waiver.
The full text of our Code of Conduct is available at the investors section of our website at www.tempesttx.com.
The reference to our website address does not constitute incorporation by reference of the information contained at or available through our website, and you should not consider it to be a part of this Annual Report.
−Removed: Delinquent Section 16(a) Reports
−Removed: Information regarding compliance with Section 16(a) of the Exchange Act required by this item will be contained in our 2024 Proxy Statement under the caption “Security Ownership of Certain Beneficial Owners and Management—Delinquent Section 16(A) Reports,” if any, and is hereby incorporated by reference.
EXECUTIVE COMPENSATION
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CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS, AND DIRECTOR INDEPENDENCE
−Removed: Information regarding Related Transactions and Director Independence required by this item will be contained in our 2024 Proxy Statement under the caption “Transactions with Related Persons and Indemnification,” and “Information Regarding the Board of Directors and Corporate Governance – Independence of the Board of Directors,” and is hereby incorporated by reference.
−Removed: PRINCIPAL ACCOUNTING FEES AND SERVICES
+Added: Information regarding Related Transactions and Director Independence required by this item will be contained in our 2025 Proxy Statement under the caption “Transactions with Related Persons and Indemnification,” and “Information Regarding the
+Added: Board of Directors and Corporate Governance – Independence of the Board of Directors,” and is hereby incorporated by reference.
+Added: PRINCIPAL ACCOUNTANT FEES AND SERVICES
Information regarding Accounting Fees and Services required by this item will be contained in our 2025 Proxy Statement in Proposal 3 under the captions “—Principal Accountant Fees and Services” and “—Pre-Approval Policies and Procedures,” and is hereby incorporated by reference.
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Warrant to Purchase Stock
−Removed: Form of Pre-Funded Warrant
−Removed: Registration Rights Agreement, dated April 26, 2022, by and among Tempest Therapeutics, Inc.
−Removed: and the persons party thereto
Rights Agreement, dated as of October 10, 2023, between Tempest Therapeutics, Inc.
and Computershare Trust Company, N.A., which includes the form of Certificate of Designation as Exhibit A, the form of Right Certificate as Exhibit B and the Summary of Rights to Purchase Preferred Shares as Exhibit C
+Added: Amendment No.
+Added: 1, dated as of October 9, 2024, to Rights Agreement, dated as of October 10, 2023, by and between Tempest Therapeutics, Inc.
+Added: and Computershare Trust Company, N.A., as rights agent
+Added: Amendment No.
+Added: 2, dated as of December 5, 2024, to Rights Agreement, dated as of October 10, 2023, as amended, by and between Tempest Therapeutics, Inc.
+Added: and Computershare Trust Company, N.A., as rights agent.
2011 Equity Incentive Plan
3 unchanged sentences
Form of Option Grant Package under 2019 Equity Incentive Plan
−Removed: Form of RSU Grant Package under 2019 Equity Incentive Plan
Form of Stock Option Agreement under the Sub Plan for French Residents under 2019 Equity Incentive Plan
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Employment Agreement, dated July 7, 2021, by and between the Company and Stephen Brady
−Removed: Employment Agreement, dated July 7, 2021, by and between the Company and Thomas Dubensky, Ph.D.
Employment Agreement, dated July 7, 2021, by and between the Company and Samuel Whiting, M.D., Ph.D.
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Form of Option Grant Package under the 2023 Inducement Plan
−Removed: Separation and Consulting Agreement by and between the Registrant and Thomas Dubensky, Ph.D., dated September 15, 2023
+Added: Roche Supply Agreement, dated October 7, 2024, by and between the Registrant and F.
+Added: Hoffmann-La Roche Ltd.
+Added: Executive Employment Agreement, dated January 1, 2025, by and between the Registrant and Nicholas Maestas
+Added: Tempest Therapeutics, Inc.
+Added: Insider Trading Policy
Subsidiaries of the Registrant
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Incentive Compensation Recoupment Policy
−Removed: Inline XBRL Instance Document
−Removed: Inline XBRL Taxonomy Extension Schema Document
−Removed: Inline XBRL Taxonomy Extension Calculation Linkbase Document
−Removed: Inline XBRL Taxonomy Extension Definition Linkbase Document
−Removed: Inline XBRL Taxonomy Extension Label Linkbase Document
−Removed: Inline XBRL Taxonomy Extension Presentation Linkbase Document
−Removed: Cover Page Interactive Data File (formatted as inline XBRL with applicable taxonomy extension contained in Exhibit 101).
+Added: Inline XBRL Instance Document – the instance document does not appear in the Interactive Data File because its XBRL tags are embedded within the Inline XBRL document
+Added: Inline XBRL Taxonomy Extension Schema With Embedded Linkbase Document
+Added: Cover Page formatted as inline XBRL with applicable taxonomy extension contained in Exhibit 101.
_______________________________________
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These certifications are being furnished solely to accompany this Annual Report pursuant to 18 U.S.C.
−Removed: Section 1350, and are not being filed for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, and are not to be incorporated by reference into any filing of the Registrant, whether made before or after the date hereof, regardless of any general incorporation language in such filing.
+Added: Section 1350, and are not being filed for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, and are not to be incorporated by
+Added: reference into any filing of the Registrant, whether made before or after the date hereof, regardless of any general incorporation language in such filing.
# Pursuant to Item 601(b)(10)(iv) of Regulation S-K, certain portions of this exhibit (indicated by ***) have been omitted because the identified information is not material and is the type that the Registrant treats as private or confidential.
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Nicholas Maestas
−Removed: Vice-President, Strategy and Finance (Principal Financial Officer)
+Added: Chief Financial Officer & Head of Corporate Strategy (Principal Financial Officer)
March 27, 2025
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/s/ Nicholas Maestas
−Removed: Vice President, Strategy and Finance and Secretary
+Added: Chief Financial Officer & Head of Corporate Strategy
(Principal Financial Officer)
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Compared sentence by sentence after normalising whitespace, quotation marks, case and digits, so re-formatting and restated figures do not read as changed language. Wording changes appear as one removal and one addition. The current filing and the prior one are authoritative.