Other Information
−Removed: During the three months ended March 31, 2026, the following adopted a “ Rule 10b5-1 trading arrangement ” (as defined in Item 408(a) of Regulation S-K) that is intended to satisfy the affirmative defense of Rule 10b5-1(c) under the Exchange Act and our policies on insider trading:
+Added: Entry into a Material Definitive Agreement
+Added: On July 27, 2026, we and certain of our affiliates entered into Amendment No.
+Added: 4 to Third Amended and Restated Loan and Security Agreement (the “Amendment”) with Hercules, which amended certain terms of the Third Amended and Restated Loan and Security Agreement, dated December 15, 2021 by and among us, certain of our subsidiaries, and Hercules, as amended by that certain Amendment No.
+Added: 1 to Third Amended and Restated Loan and Security Agreement, dated as of May 12, 2023, Consent and Amendment No.
+Added: 2 to Third Amended and Restated Loan and Security Agreement, dated as of June 28, 2024, and Amendment No.
+Added: 3 to Third Amended and Restated Loan and Security Agreement.
+Added: The Amendment, among other things, extends the period we can draw the $100.0 million term loan tranche from June 15, 2027 to September 30, 2027.
+Added: Except as provided for in the amendment, the terms of borrowing under the 2026 Amended Facility otherwise remain unchanged.
+Added: The foregoing description of the Amendment does not purport to be complete and is qualified in its entirety by reference to the full text of the Amendment, a copy of which is filed as Exhibit 10.2 hereto and is incorporated herein by reference.
+Added: Adoption of 10b5-1 Trading Plans by Our Officers and Directors
+Added: During the three months ended June 30, 2026, the following adopted a “ Rule 10b5-1 trading arrangement ” (as defined in Item 408(a) of Regulation S-K) that is intended to satisfy the affirmative defense of Rule 10b5-1(c) under the Exchange Act and our policies on insider trading:
Date Adopted (1)
1 unchanged sentence
Expiration Date (2)
−Removed: Madhavan Balachandran , Non-executive Director
−Removed: March 10, 2026
+Added: David Meek , Non-executive Director
December 18, 2026
2 unchanged sentences
(2) The Rule 10b5-1 trading arrangement is scheduled to expire on the date listed in the table, subject to earlier termination upon the sale of all shares subject to the Rule 10b5-1 trading arrangement, or as otherwise provided in the Rule 10b5-1 trading arrangement.
−Removed: Other than those disclosed above, none of our directors or officers adopted, modified, or terminated a “Rule 10b5-1 trading arrangement” or “ non-Rule 10b5-1 trading arrangement ,” in each case as defined in Item 408 of Regulation S-K, during the three months ended March 31, 2026.
+Added: Other than those disclosed above, none of our directors or officers adopted, modified, or terminated a “Rule 10b5-1 trading arrangement” or “ non-Rule 10b5-1 trading arrangement ,” in each case as defined in Item 408 of Regulation S-K, during the three months ended June 30, 2026.
See the Exhibit Index immediately preceding the signature page to this Quarterly Report on Form 10-Q for a list of exhibits filed or furnished with this report, which Exhibit Index is incorporated herein by reference.
EXHIBIT INDEX
−Removed: Termination and Amendment Agreement, dated April 15, 2026, by and between uniQure biopharma B.V.
−Removed: and CSL Behring LLC.
+Added: Amended Articles of Association of uniQure N.V.
+Added: (incorporated by reference to Exhibit 3.1 of the Company’s Current Report on Form 8-K (file no.
+Added: 001-36294) filed with the SEC on June 15, 2026).
+Added: Amended and Restated 2014 Share Incentive Plan of uniQure N.V.
+Added: ( incorporated by reference to Exhibit 1 0 .1 of the Company’s Current Report on Form 8-K (file no.
+Added: 001-36294) filed with the SEC on June 15, 2026 ).
+Added: Amendment No.
+Added: 4 to Third Amended and Restated Loan and Security Agreement, dated July 27, 2026, by and among uniQure biopharma, B.V., uniQure, Inc., uniQure IP B.V., uniQure N.V.
+Added: and Hercules Capital, Inc.
Certification of Chief Executive Officer pursuant to Rule 13a-14(a) or 15d-14(a) of the Securities and Exchange Act of 1934, as amended, as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.
2 unchanged sentences
Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002 .
−Removed: The following financial information from our Quarterly Report on Form 10-Q for the period ended March 31, 2026, filed with the Securities and Exchange Commission on May 5, 2026, is formatted in Inline Extensible Business Reporting Language (“iXBRL”):
+Added: The following financial information from our Quarterly Report on Form 10-Q for the period ended June 30, 2026, filed with the Securities and Exchange Commission on July 29, 2026, is formatted in Inline Extensible Business Reporting Language (“iXBRL”):
(i) Consolidated Balance Sheets;
3 unchanged sentences
and (v) Notes to Consolidated Financial Statements (tagged as blocks of text).
−Removed: The cover page from our Quarterly Report on Form 10-Q for the period ended March 31, 2026, filed with the Securities and Exchange Commission on May 5, 2026, is formatted in Inline Extensible Business Reporting Language (“iXBRL”).
+Added: The cover page from our Quarterly Report on Form 10-Q for the period ended June 30, 2026, filed with the Securities and Exchange Commission on July 29, 2026, is formatted in Inline Extensible Business Reporting Language (“iXBRL”).
* Filed herewith.
10 unchanged sentences
(Principal Financial and Accounting Officer)
+Added: July 29, 2026
Compared sentence by sentence after normalising whitespace, quotation marks, case and digits, so re-formatting and restated figures do not read as changed language. Wording changes appear as one removal and one addition. The current filing and the prior one are authoritative.