What changed in this filing

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Item 1A. Risk Factors

2026-09-03 compared with 2025-03-28 · 100 added, 104 removed, 323 unchanged (39% of the section changed)

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Our ability to successfully generate

revenues from our intellectual property is dependent on a number of factors, including availability of funds to complete development

efforts, to adequately test and refine our products, and to commercialize our products.

There can be no assurance that we will

not encounter setbacks with our products, or that funding will be sufficient to bring our products to the point of commercialization.

We are dependent on our key personnel, and

the loss of such personnel could adversely affect our business.

We depend on the continued performance of the members of

our management team and our Business and Scientific Advisory Board who have contributed to the expertise of our team and the position

of our business.

If we lose the services of members of our management teams, and are unable to locate a suitable replacement in

a timely manner, it could have a material adverse effect on our business.

We do not expect to obtain key man life insurance for

any members of management in the foreseeable future.

revenues from our intellectual property is dependent on a number of factors, including availability of funds to complete development efforts,

to adequately test and refine our products, and to commercialize our products.

There can be no assurance that we will not encounter

setbacks with our products, or that funding will be sufficient to bring our products to the point of commercialization.

We are dependent on our key personnel, and the

loss of such personnel could adversely affect our business.

We depend on the continued performance of the members of our

management team and our Business and Scientific Advisory Board who have contributed to the expertise of our team and the position of our

If we lose the services of members of our management teams, and are unable to locate a suitable replacement in a timely

manner, it could have a material adverse effect on our business.

We do not expect to obtain key man life insurance for any members

of management in the foreseeable future.

We may experience difficulty implementing our

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There can be no assurance that we would be able to obtain additional capital on reasonable terms, or at all.

We may be adversely affected by the effects of inflation.

management has determined that inflation has not had a material effect on the Company in 2024, inflation has the potential to adversely

affect our liquidity, business, financial condition and results of operations by increasing our overall cost structure.

The existence

of inflation in the economy has resulted in, and may continue to result in, higher interest rates and capital costs, supply shortages,

increased costs of labor, components, manufacturing and shipping, as well as weakening exchange rates and other similar effects.

result of inflation, we have experienced and may continue to experience cost increases.

Although we may take measures to mitigate the

effects of inflation, if these measures are not effective, our business, financial condition, results of operations and liquidity could

be materially adversely affected.

Even if such measures are effective, there could be a difference between the timing of when these beneficial

actions impact our results of operations and when the cost of inflation is incurred.

We may be adversely affected by the effects

of inflation.

While management has determined that inflation has not had a material effect on the Company in 2025, inflation has

the potential to adversely affect our liquidity, business, financial condition and results of operations by increasing our overall cost

The existence of inflation in the economy has resulted in, and may continue to result in, higher interest rates and capital

costs, supply shortages, increased costs of labor, components, manufacturing and shipping, as well as weakening exchange rates and other

similar effects.

As a result of inflation, we have experienced and may continue to experience cost increases.

Although we may take measures

to mitigate the effects of inflation, if these measures are not effective, our business, financial condition, results of operations and

liquidity could be materially adversely affected.

Even if such measures are effective, there could be a difference between the timing

of when these beneficial actions impact our results of operations and when the cost of inflation is incurred.

Increased cybersecurity vulnerabilities and

threats, and more sophisticated and targeted cyberattacks and other security incidents, pose risks to our systems, data and business

and our relationships with third parties.

In the course of conducting our business, we may hold or have access to sensitive,

confidential, proprietary or personal data or information belonging to us, our employees or third parties.

Increased cybersecurity vulnerabilities

and threats, and more sophisticated and targeted cyberattacks and other security incidents, pose risks to our and our third-party service

threats, and more sophisticated and targeted cyberattacks and other security incidents, pose risks to our systems, data and business and

our relationships with third parties.

In the course of conducting our business, we may hold or have access to sensitive, confidential,

proprietary or personal data or information belonging to us, our employees or third parties.

Increased cybersecurity vulnerabilities and

threats, and more sophisticated and targeted cyberattacks and other security incidents, pose risks to our and our third-party service

providers' systems, data, and business, and the confidentiality, availability and integrity of our data.

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remediation efforts may not be successful.

The inability to implement, maintain and upgrade adequate safeguards could materially and

adversely affect our results of operations and financial condition.

The inability to implement, maintain and upgrade adequate safeguards could materially and adversely

affect our results of operations and financial condition.

Despite our and our third-party service providers'

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and, as a result, third parties may or could have access to our confidential information.

The secure maintenance of this information

is critical to our business and reputation.

The secure maintenance of this information is

critical to our business and reputation.

We believe that companies have been increasingly subject to a wide variety of security incidents,

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may be custom-crafted against our information systems.

Cyber-attacks continue to become more prevalent and much harder to detect and

defend against.

Our network and storage applications and those of our vendors may be subject to unauthorized access by hackers or breached

due to operator error, malfeasance or other system disruptions.

It is often difficult to anticipate or immediately detect such incidents

and the damage caused by such incidents.

Cyber-attacks continue to become more prevalent and much harder to detect and defend

Our network and storage applications and those of our vendors may be subject to unauthorized access by hackers or breached due

to operator error, malfeasance or other system disruptions.

It is often difficult to anticipate or immediately detect such incidents and

the damage caused by such incidents.

These data breaches and any unauthorized access or disclosure of our information or intellectual

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expense and cause significant harm to our reputation and business.

Privacy breaches and other cyber security

risks related to our business could negatively affect our reputation, credibility and business.

We are likely to be

dependent on information technology systems and networks for a significant portion of our direct-to-consumer sales, including our

e-commerce sites and retail business credit card transaction authorization and processing.

We are responsible for storing data

relating to our customers and employees and also rely on third party vendors for the storage, processing and transmission of

personal and Company information.

In addition to taking the necessary precautions ourselves, we require that third-party service

providers implement reasonable security measures to protect our employees’ and customers’ identity and privacy.

not, however, control these third-party service providers and cannot guarantee that no electronic or physical computer break-ins or

security breaches will occur in the future.

Our systems and technology are vulnerable from time-to-time to damage, disruption or

interruption from, among other things, physical damage, natural disasters, inadequate system capacity, system issues, security

breaches, “hackers,” email blocking lists, computer viruses, power outages and other failures or disruptions outside of

A significant breach of customer, employee or Company data could damage our reputation, our relationship with customers

and our brands, and could result in lost sales, sizable fines, significant breach-notification costs and lawsuits, as well as

adversely affect our results of operations.

We may also incur additional costs in the future related to the implementation of

additional security measures to protect against new or enhanced data security and privacy threats, or to comply with state, federal

Privacy breaches and other cyber security risks

related to our business could negatively affect our reputation, credibility and business.

We are likely to be dependent on information

technology systems and networks for a significant portion of our direct-to-consumer sales, including our e-commerce sites and retail business

credit card transaction authorization and processing.

We are responsible for storing data relating to our customers and employees and

also rely on third party vendors for the storage, processing and transmission of personal and Company information.

In addition to taking

the necessary precautions ourselves, we require that third-party service providers implement reasonable security measures to protect our

employees’ and customers’ identity and privacy.

We do not, however, control these third-party service providers and cannot

guarantee that no electronic or physical computer break-ins or security breaches will occur in the future.

Our systems and technology

are vulnerable from time-to-time to damage, disruption or interruption from, among other things, physical damage, natural disasters, inadequate

system capacity, system issues, security breaches, “hackers,” email blocking lists, computer viruses, power outages and other

failures or disruptions outside of our control.

A significant breach of customer, employee or Company data could damage our reputation,

our relationship with customers and our brands, and could result in lost sales, sizable fines, significant breach-notification costs and

lawsuits, as well as adversely affect our results of operations.

We may also incur additional costs in the future related to the implementation

of additional security measures to protect against new or enhanced data security and privacy threats, or to comply with state, federal

and international laws that may be enacted to address those threats.

We have been and expect to be significantly

dependent on our collaborative agreements for the research, development and testing of AAGP ® , which exposes us to the

risk of reliance on the performance of third parties.

In conducting our research and development activities, we currently

rely, and expect to continue to rely, on numerous collaborative agreements with third parties such as contract research organizations,

commercial partners, universities, governmental agencies and not-for-profit organizations for both strategic and financial resources.

The loss of, or failure to perform by us or our partners (who are subject to regulatory, competitive and other risks) under any applicable

agreements or arrangements, or our failure to secure additional agreements for our product candidates, would substantially disrupt or

delay our research and development and commercialization activities.

Any such loss would likely increase our expenses and materially

harm our business, financial condition and results of operations.

dependent on our collaborative agreements for the research, development and testing of AAGP ® , which exposes us to the risk

of reliance on the performance of third parties.

In conducting our research and development activities, we currently rely,

and expect to continue to rely, on numerous collaborative agreements with third parties such as contract research organizations, commercial

partners, universities, governmental agencies and not-for-profit organizations for both strategic and financial resources.

of, or failure to perform by us or our partners (who are subject to regulatory, competitive and other risks) under any applicable agreements

or arrangements, or our failure to secure additional agreements for our product candidates, would substantially disrupt or delay our research

and development and commercialization activities.

Any such loss would likely increase our expenses and materially harm our business,

financial condition and results of operations.

We may have difficulty raising any needed additional

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company that has not yet developed or sold any products.

To date, we have not yet developed nor marketed

To date, we have not yet developed nor marketed a

Ongoing testing of the AAGP ® molecule with three amino acids joined to a monosaccharide by a gemdiflouride

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obtain regulatory approval they may never achieve market acceptance or commercial success.

Even if we develop products

and obtain FDA or other regulatory approvals, our products may not achieve market acceptance among physicians, patients and third party

payors and, ultimately, may not be commercially successful.

Market acceptance of our product candidates for which we receive approval

depends on a number of factors.

Any failure by our product candidates that obtain regulatory approval to achieve market acceptance

or commercial success would adversely affect our financial results.

Even if we develop products and

obtain FDA or other regulatory approvals, our products may not achieve market acceptance among physicians, patients and third party payors

and, ultimately, may not be commercially successful.

Market acceptance of our product candidates for which we receive approval depends

on a number of factors.

Any failure by our product candidates that obtain regulatory approval to achieve market acceptance or commercial

success would adversely affect our financial results.

The potential widespread acceptance of therapies that

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General Corporate Risk Factors

Insiders continue to have substantial

control over the Company.

As of March 28, 2025, the Company’s directors and executive officers hold the current right

to vote approximately 34.3% of the Company’s outstanding voting stock;

of which 28.8% is owned or controlled, directly or indirectly

by the Company CEO, Clarence Smith.

In addition, the Company’s directors and executive officers have the right to acquire additional

shares which could increase their voting percentage significantly.

As a result, Mr.

Smith acting alone, and/or many of these individuals

acting together, may have the ability to exert significant control over the Company’s decisions and control the management and affairs

of the Company, and also to determine the outcome of matters submitted to stockholders for approval, including the election and removal

of a director, the removal of any officer and any merger, consolidation or sale of all or substantially all of the Company’s assets.

Accordingly, this concentration of ownership may harm a future market price of the Company’s common stock by:

• Delaying, deferring

or preventing a change in control of the Company;

• Impeding a merger,

consolidation, takeover or other business combination involving the Company;

• Discouraging a

potential acquirer from making a tender offer or otherwise attempting to obtain control of the Company .

Insiders control over the Company.

As of September 3, 2026, the Company’s directors and executive

officers hold the current right to vote approximately 7.83% of the Company’s outstanding voting stock.

In addition, the heir to

the deceased CEO’s estate holds approximately 35.8% of outstanding voting stock.

The Company’s directors and executive officers have the right to

acquire additional shares which could increase their voting percentage significantly.

As a result, many of these individuals acting together,

may have the ability to exert significant control over the Company’s decisions and control the management and affairs of the Company,

and also to determine the outcome of matters submitted to stockholders for approval, including the election and removal of a director,

the removal of any officer and any merger, consolidation or sale of all or substantially all of the Company’s assets.

this concentration of ownership may harm a future market price of the Company’s common stock by:

Delaying, deferring or preventing a change in control of the Company;

Impeding a merger, consolidation, takeover or other business combination involving the Company;

Discouraging a potential acquirer from making a tender offer or otherwise attempting to obtain control of the Company .

The Company may not be able to continue

as a going concern.

Our independent public accountants noted that our recurring losses from operations ($364,188 and $415,479

for the years ended December 31, 2024 and 2023, respectively) and negative net operating cash flow ($223,050 and $375,989 for the years

ended December 31, 2024 and 2023, respectively) raise substantial doubt about our ability to continue as a going concern.

This may hinder

our future ability to obtain financing or may force us to obtain financing on less favorable terms than would otherwise be available.

Our independent public accountants noted that our recurring losses

from operations ($393,650 and $364,188 for the years ended December 31, 2025 and 2024, respectively) and negative net operating cash flow

$135,377 and $223,050 for the years ended December 31, 2025 and 2024, respectively) raise substantial doubt about our ability to continue

as a going concern.

This may hinder our future ability to obtain financing or may force us to obtain financing on less favorable terms

than would otherwise be available.

The Company is dependent upon additional

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Compared sentence by sentence after normalising whitespace, quotation marks, case and digits, so re-formatting and restated figures do not read as changed language. Wording changes appear as one removal and one addition. The current filing and the prior one are authoritative.

What changed 10-K

Item 1A. Risk Factors