15 unchanged sentences
Other Information.
−Removed: Insider Trading Arrangement
+Added: Trading Arrangements
During the quarter ended December 31, 2025, none of our directors and officers (as defined in Rule 16a-1(f) under the Exchange Act) adopted, modified or terminated any contract, instruction, or written plan for the purchase or sale of our securities that was intended to satisfy the affirmative defense conditions of Rule 10b5-1(c) under the Exchange Act or any “non-Rule 10b5-1 trading arrangement” as defined in Item 408(c) of Regulation S-K.
3 unchanged sentences
Directors, Executive Officers and Corporate Governance.
−Removed: The information required by this item is incorporated by reference to the information set forth in the sections titled “Proposal 1:
−Removed: Election of Directors,” “Information Regarding the Board of Directors and Corporate Governance,” “Information Regarding Executive Officers” and “Delinquent Section 16(a) Reports,” if applicable, in our 2025 Proxy Statement.
+Added: Identification of Directors and Executive Officers
+Added: Information regarding directors and executive officers required by this item will be contained in our 2026 Proxy Statement under the captions “Proposal 1:
+Added: Election of Directors,” “Information Regarding Director Nominees and Continuing Directors,” and “Information Regarding Executive Officers,” and is hereby incorporated by reference.
+Added: Identification of Audit Committee
+Added: Information regarding our Audit Committee required by this item will be contained in our 2026 Proxy Statement under the caption “Information Regarding the Board of Directors and Corporate Governance,” and is hereby incorporated by reference.
+Added: Material Changes to Procedures for Recommending Directors
+Added: Information regarding procedures for recommending directors required by this item will be contained in our 2026 Proxy Statement under the caption “Information Regarding the Board of Directors and Corporate Governance,” and is hereby incorporated by reference.
+Added: Delinquent Section 16(a) Reports
+Added: Information regarding compliance with Section 16(a) of the Exchange Act required by this item will be contained in our 2026 Proxy Statement under the caption “Delinquent Section 16(a) Reports,” and such disclosure, if any, is hereby incorporated by reference.
+Added: Code of Conduct
Information regarding our Code of Business Conduct and Ethics, or the Code of Conduct, required by this item will be contained in our 2026 Proxy Statement under the caption “Information Regarding the Board of Directors and Corporate Governance – Code of Ethics,” and is hereby incorporated by reference.
2 unchanged sentences
The reference to our website address does not constitute incorporation by reference of the information contained at or available through our website, and you should not consider it to be a part of this Annual Report.
+Added: Insider Trading Policy
+Added: The information required by Item 408(b) of Regulation S-K is incorporated by reference from the information contained in our 2026 Proxy Statement under the heading “Information Regarding the Board of Directors and Corporate Governance.”
Executive Compensation.
1 unchanged sentence
Security Ownership of Certain Beneficial Owners and Management and Related Stockholder Matters.
−Removed: The information required by this item is incorporated by reference to the information set forth in the sections titled “Equity Compensation Plans at December 31, 2021” and “Security Ownership of Certain Beneficial Owners and Management” in our 2025 Proxy Statement.
+Added: The information required by this item is incorporated by reference to the information set forth in the sections titled “Security Ownership of Certain Beneficial Owners and Management” and “Securities Authorized for issuance under Equity Compensation Plans” in our 2026 Proxy Statement.
Certain Relationships and Related Transactions, and Director Independence
31 unchanged sentences
Forms of Restricted Stock Unit Grant Notice and Award Agreement (RSU Award) under 2021 Equity Incentive Plan
+Added: 10-K 001-40377 10.5 March 4, 2025
10.6+ 2021 Employee Stock Purchase Plan.
33 unchanged sentences
10.21+ Non-Employee Director Compensation Policy, as amended as of October 30, 2024.
+Added: 10-K 001-40377 10.5 March 4, 2025
Office Lease, dated August 24, 2011, by and between the Company and BXP Research Park LP (f/k/a BP MV Research Park LLC).
16 unchanged sentences
S-3 333-268243 1.2 November 8, 2022
+Added: 10.31 Stock Purchase Agreement, dated February 13, 2025, by and between the Registrant and KCK Ltd.
+Added: 10-Q 001-40337 10.1 May 13, 2025
+Added: 10.32 Separation Agreement, dated June 20, 2025, by and between the Company and Rebecca Kuhn.
+Added: 10-Q 001-40337 10.1 August 12, 2025
+Added: 10.33+ Offer Letter, dated June 5, 2025, by and between the Company and Patrick Williams.
+Added: 10-Q 001-40337 10.2 August 12, 2025
+Added: 10.34# Credit, Security and Guaranty Agreement, dated June 4, 2025, by and among the Company, MidCap Funding IV Trust, as agent, MidCap Financial Trust, as term loan servicer and the financial institutions and other entities from time to time party thereto .
+Added: 10-Q 001-40337 10.3 August 12, 2025
19.1 Insider Trading Policy
+Added: 10-K 001-40377 10.5 March 4, 2025
Consent of PricewaterhouseCoopers LLP, independent registered public accounting firm.
11 unchanged sentences
+ Indicates management contract or compensatory plan.
−Removed: * The certifications attached as Exhibit 32.1 and 32.2 accompany this Annual Report on Form 10-K pursuant to 18 U.S.C.
−Removed: Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, and shall not be deemed “filed” by the Registrant for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, and are not to be incorporated by reference into any of the Registrant’s filings under the Securities Act of 1933, as amended, irrespective of any general incorporation language contained in any such filing.
+Added: # Schedules and exhibits to this agreement have been omitted in accordance with Rule 601(a)(5) of Regulation S-K.
+Added: The Company will provide a copy of any omitted schedule or exhibit to the SEC or its staff upon request.
+Added: * The certification attached as Exhibit 32.1 accompanies this Annual Report on Form 10-K pursuant to 18 U.S.C.
+Added: Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, and shall not be deemed “filed” by the Registrant for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, and is not to be incorporated by reference into any of the Registrant’s filings under the Securities Act of 1933, as amended, irrespective of any general incorporation language contained in any such filing.
** Portions of this exhibit (indicated by [*]) have been omitted because the registrant has determined that the information is both not material and is the type that the registrant treats as private or confidential.
5 unchanged sentences
(Principal Executive Officer)
−Removed: /s/ Rebecca Kuhn
−Removed: Chief Financial Officer and Vice President, Finance and Administration (Principal Financial Officer and Principal Accounting Officer)
+Added: /s/ Patrick F.
+Added: Chief Financial Officer (Principal Financial and Accounting Officer)
POWER OF ATTORNEY
−Removed: KNOW ALL PERSONS BY THESE PRESENTS, that each person whose signature appears below constitutes and appoints Joel Becker and Rebecca Kuhn, jointly and severally, as his or her true and lawful attorneys-in-fact and agents, with full power of substitution and resubstitution, for him or her and in his or her name, place, and stead, in any and all capacities, to sign any and all amendments to this Annual Report on Form 10-K, and to file the same, with all exhibits thereto, and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorneys-in-fact and agents full power and authority to do and perform each and every act and thing requisite and necessary to be done in and about the premises, as fully to all intents and purposes as he might or could do in person, hereby ratifying and confirming that all said attorneys-in-fact and agents, or his or her or their substitute or substitutes, may lawfully do or cause to be done by virtue hereof.
+Added: KNOW ALL PERSONS BY THESE PRESENTS, that each person whose signature appears below constitutes and appoints Joel Becker and Patrick F.
+Added: Williams, jointly and severally, as his or her true and lawful attorneys-in-fact and agents, with full power of substitution and resubstitution, for him or her and in his or her name, place, and stead, in any and all capacities, to sign any and all amendments to this Annual Report on Form 10-K, and to file the same, with all exhibits thereto, and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorneys-in-fact and agents full power and authority to do and perform each and every act and thing requisite and necessary to be done in and about the premises, as fully to all intents and purposes as he might or could do in person, hereby ratifying and confirming that all said attorneys-in-fact and agents, or his or her or their substitute or substitutes, may lawfully do or cause to be done by virtue hereof.
Pursuant to the requirements of the Securities Exchange Act of 1934, this Annual Report on Form 10-K has been signed below by the following persons on behalf of the Registrant and in the capacities and on the dates indicated:
−Removed: /s/ Joel Becker Director, President and Chief Executive Officer
+Added: /s/ Joel Becker
+Added: Director, President and Chief Executive Officer
(Principal Executive Officer)
March 3, 2026
−Removed: /s/ Rebecca Kuhn Chief Financial Officer and Vice President, Finance and Administration (Principal Financial Officer and Principal Accounting Officer)
+Added: /s/ Patrick F.
+Added: Chief Financial Officer (Principal Financial and Accounting Officer) March 3, 2026
+Added: /s/ Frank Fischer
March 3, 2026
−Removed: /s/ Frank Fischer Director March 4, 2025
Frank Fischer
−Removed: /s/ Lisa Andrade Director March 4, 2025
−Removed: /s/ Uri Geiger Director March 4, 2025
−Removed: /s/ Scott Huennekens Director March 4, 2025
+Added: /s/ Lisa Andrade
+Added: March 3, 2026
+Added: /s/ Uri Geiger
+Added: March 3, 2026
+Added: /s/ Scott Huennekens
+Added: March 3, 2026
Scott Huennekens
−Removed: /s/ Rakhi Kumar Director March 4, 2025
+Added: /s/ Rakhi Kumar
+Added: March 3, 2026
/s/ Joseph S.
−Removed: Lacob Director March 4, 2025
−Removed: /s/ Renee Ryan Director March 4, 2025
+Added: March 3, 2026
+Added: /s/ Renee Ryan
+Added: March 3, 2026
Compared sentence by sentence after normalising whitespace, quotation marks, case and digits, so re-formatting and restated figures do not read as changed language. Wording changes appear as one removal and one addition. The current filing and the prior one are authoritative.