21 unchanged sentences
Report of Independent Registered Public Accounting Firm
−Removed: To the Shareholders and the Board of Directors of Neurocrine Biosciences, Inc.
+Added: To the Stockholders and the Board of Directors of Neurocrine Biosciences, Inc.
Opinion on Internal Control over Financial Reporting
23 unchanged sentences
Other Information
+Added: On February 8, 2022, we entered into a lease agreement, or the Lease, with Gemdale Aperture Phase I, LLC for the lease of approximately 535,000 gross square feet of office, laboratory and ancillary space, or the Premises, on a 15.72-acre campus located at 6040 Edgewood Bend Court, San Diego, California 92130, or the Property, for our future principal executive offices, and laboratory space for research and development and related uses.
+Added: The Premises will be delivered to us in two phases, with the initial Premises consisting of two buildings containing a total of approximately 240,000 gross square feet, or Phase 1, and the subsequent premises consisting of two buildings containing a total of approximately 295,000 gross square feet, or Phase 2.
+Added: We also have the option to expand into a to-be-constructed fifth building, which would contain approximately 121,000 gross square feet, subject to the terms set forth in the Lease.
+Added: Subject to certain conditions set forth in the Lease, we also have a right of first refusal to purchase the Property.
+Added: The commencement date for Phase 1 is expected to occur on or around March 28, 2023, or the Phase 1 Commencement Date, and the commencement date for Phase 2 is expected to occur on or around February 1, 2025.
+Added: The Lease will have an initial term of approximately 13 years and 7 months, commencing on the Phase 1 Commencement Date, unless terminated earlier, or the Term.
+Added: We have two options to extend the Term by five years each.
+Added: Base rent for each of Phase 1 and Phase 2 will be abated for 10 months following the Phase 1 Commencement Date and Phase 2 Commencement Date, respectively.
+Added: Following the abatement period for Phase 1, the base rent payable for Phase 1 will be $6.00 per gross square foot, or approximately $1.4 million per month, which amount will increase by 3% per year over the Term.
+Added: Following the abatement period for Phase 2, the per gross square foot base rent payable for Phase 2 will be equal to the per gross square foot base rent being paid for the Phase 1 Premises at such time.
+Added: We will also enter into a letter of credit equal to base rent due for the Premises during the last month of the initial Term.
+Added: Upon vacating our current principal executive offices at 12780 El Camino Real, San Diego, California 92130, we intend to sublet such facilities.
+Added: The foregoing description of the material terms of the Lease is qualified in its entirety by reference to the full text of the Lease, a copy of which will be filed as an exhibit to a subsequent filing with the SEC.
Directors, Executive Officers and Corporate Governance
−Removed: Information required by this item will be contained in our Definitive Proxy Statement for our 2021 Annual Meeting of Stockholders, to be filed pursuant to Regulation 14A with the Securities and Exchange Commission within 120 days of December 31, 2020.
+Added: Information required by this item will be contained in our Definitive Proxy Statement for our 2022 Annual Meeting of Stockholders, to be filed pursuant to Regulation 14A with the SEC within 120 days of December 31, 2021.
Such information is incorporated herein by reference.
4 unchanged sentences
Executive Compensation
−Removed: Information required by this item will be contained in our Definitive Proxy Statement for our 2021 Annual Meeting of Stockholders, to be filed pursuant to Regulation 14A with the Securities and Exchange Commission within 120 days of December 31, 2020.
+Added: Information required by this item will be contained in our Definitive Proxy Statement for our 2022 Annual Meeting of Stockholders, to be filed pursuant to Regulation 14A with the SEC within 120 days of December 31, 2021.
Such information is incorporated herein by reference.
Security Ownership of Certain Beneficial Owners and Management and Related Stockholder Matters
−Removed: Information required by this item will be contained in our Definitive Proxy Statement for our 2021 Annual Meeting of Stockholders, to be filed pursuant to Regulation 14A with the Securities and Exchange Commission within 120 days of December 31, 2020.
+Added: Information required by this item will be contained in our Definitive Proxy Statement for our 2022 Annual Meeting of Stockholders, to be filed pursuant to Regulation 14A with the SEC within 120 days of December 31, 2021.
Such information is incorporated herein by reference.
Certain Relationships and Related Transactions, and Director Independence
−Removed: Information required by this item will be contained in our Definitive Proxy Statement for our 2021 Annual Meeting of Stockholders, to be filed pursuant to Regulation 14A with the Securities and Exchange Commission within 120 days of December 31, 2020.
+Added: Information required by this item will be contained in our Definitive Proxy Statement for our 2022 Annual Meeting of Stockholders, to be filed pursuant to Regulation 14A with the SEC within 120 days of December 31, 2021.
Such information is incorporated herein by reference.
Principal Accounting Fees and Services
−Removed: Information required by this item will be contained in our Definitive Proxy Statement for our 2021 Annual Meeting of Stockholders, to be filed pursuant to Regulation 14A with the Securities and Exchange Commission within 120 days of December 31, 2020.
+Added: Information required by this item will be contained in our Definitive Proxy Statement for our 2022 Annual Meeting of Stockholders, to be filed pursuant to Regulation 14A with the SEC within 120 days of December 31, 2021.
Such information is incorporated herein by reference.
8 unchanged sentences
Consolidated Statements of Cash Flows for the years ended December 31, 2021, 2020 and 2019
−Removed: Notes to the Consolidated Financial Statements (includes unaudited Selected Quarterly Financial Data)
+Added: Notes to the Consolidated Financial Statements
List of all Financial Statement schedules.
8 unchanged sentences
3.2 Description:
−Removed: Incorporated by reference to Exhibit 3.2 of the Company’s Quarterly Report on Form 10-Q filed on November 5, 2018
−Removed: 3.3 Description:
−Removed: First Amendment of Bylaws
−Removed: Incorporated by reference to Exhibit 3.1 of the Company’s Current Report on Form 8-K filed on February 4, 2020
−Removed: 3.4 Description:
−Removed: Second Amendment of Bylaws
−Removed: Incorporated by reference to Exhibit 3.1 of the Company’s Current Report on Form 8-K filed on August 28, 2020
+Added: Incorporated by reference to Exhibit 3.2 of the Company's Quarterly Report on Form 10-Q filed on May 5, 2021
4.1 Description:
6 unchanged sentences
4.3 Description:
+Added: First Supplemental Indenture, dated as of December 22, 2021, by and between the Company and U.S.
+Added: Bank National Association, as Trustee
+Added: 4.4 Description:
Form of Note representing the Company’s 2.25% Convertible Notes due 2024
33 unchanged sentences
and the Company as amended on August 31, 2011
−Removed: Incorporated by reference to Exhibit 10.2 of the Company’s Quarterly Report on Form 10-Q filed on July 29, 2010
+Added: Incorporated by reference to Exhibit 10.1 of the Company's Quarterly Report on Form 10-Q filed on May 5, 2021
10.2** Description:
First Amendment to Collaboration and License Agreement Dated August 31, 2011 between the Company and Abbott International Luxemburg S.a.r.l.
−Removed: Incorporated by reference to Exhibit 10.2 of the Company’s Quarterly Report on Form 10-Q filed on October 31, 2011
+Added: Incorporated by reference to Exhibit 10.2 of the Company's Quarterly Report on Form 10-Q filed on May 5, 2021
10.3** Description:
Collaboration and License Agreement dated March 31, 2015 between Mitsubishi Tanabe Pharma Corporation and the Company
−Removed: Incorporated by reference to Exhibit 10.1 of the Company’s Quarterly Report on Form 10-Q filed on April 30, 2015
+Added: Incorporated by reference to Exhibit 10.3 of the Company's Quarterly Report on Form 10-Q filed on May 5, 2021
10.4** Description:
1 unchanged sentence
and the Company
−Removed: Incorporated by reference to Exhibit 99.4 of the Company’s Current Report on Form 8-K filed on April 25, 2017
+Added: Incorporated by reference to Exhibit 10.4 of the Company's Quarterly Report on Form 10-Q filed on May 5, 2021
10.5* Description:
18 unchanged sentences
Incorporated by reference to Exhibit 10.3 of the Company’s Quarterly Report on Form 10-Q filed on August 3, 2020
+Added: 10.10** Description:
+Added: Collaboration and License Agreement dated November 22, 2021 between Heptares Therapeutics Limited and the Company
Equity Plans and Related Agreements :
22 unchanged sentences
2020 Equity Incentive Plan
−Removed: Incorporated by reference to Exhibit 10.2 of the Company’s Quarterly Report on Form 10-Q filed on August 3, 2020
Agreements with Officers and Directors :
37 unchanged sentences
* Confidential treatment has been granted with respect to certain portions of the exhibit.
−Removed: ** Certain portions of the exhibit have been omitted because the omitted information is not material and would likely cause competitive harm if publicly disclosed.
+Added: ** Certain information in this exhibit has been omitted pursuant to Item 601 of Regulation S-K.
*** These certifications are being furnished solely to accompany this annual report pursuant to 18 U.S.C.
25 unchanged sentences
Rastetter, Ph.D.
+Added: /s/ Johanna Mercier
+Added: Johanna Mercier
/s/ George J.
1 unchanged sentence
/s/ Richard F.
−Removed: /s/ Stephen A.
−Removed: Sherwin, M.D.
/s/ Shalini Sharp
Shalini Sharp
+Added: /s/ Stephen A.
+Added: Sherwin, M.D.
Compared sentence by sentence after normalising whitespace, quotation marks, case and digits, so re-formatting and restated figures do not read as changed language. Wording changes appear as one removal and one addition. The current filing and the prior one are authoritative.