4 unchanged sentences
• Our drug candidates are subject to a lengthy and uncertain regulatory process that may not result in the necessary regulatory approvals, which could adversely affect our and our collaborators’ ability to commercialize products.
−Removed: • We depend on our ability to gain alignment with certain regulatory authorities on our regulatory strategy for sotagliflozin in heart failure.
−Removed: If we fail to effectively gain such alignment, our business will suffer and our stock price will likely decline.
+Added: • We depend on our ability to gain alignment with certain regulatory authorities on our regulatory strategy for sotagliflozin in heart failure and obtain regulatory approval to market sotagliflozin for heart failure in the United States.
+Added: If we fail to effectively gain such alignment or obtain such regulatory approval, our business will suffer and our stock price will likely decline.
• The commercial success of any products that we or our collaborators may develop will depend upon the degree of market acceptance among physicians, patients, health care payers and the medical community.
9 unchanged sentences
Risks Related to Our Capital Requirements and Financial Results
−Removed: • We will need additional capital in the future and, if it is unavailable, we will be forced to delay, reduce or eliminate our research and development programs.
+Added: • We will need additional capital in the future and, if it is unavailable, we will be forced to delay, reduce or eliminate our research and development programs and our planned commercial launch, if approved, of sotagliflozin for heart failure in the United States.
If additional capital is not available on reasonable terms, we will be forced to obtain funds, if at all, by entering into financing agreements on unattractive terms.
3 unchanged sentences
Risks Related to Our Relationships with Third Parties
−Removed: • We depend on our ability to establish a strategic collaboration for the commercialization of sotagliflozin in heart failure.
−Removed: If we are unable to establish such a collaboration, sotagliflozin may not be commercialized in heart failure, our business will suffer and our stock price will likely decline.
• We depend on our ability to establish collaborations with pharmaceutical and biotechnology companies for the development and commercialization of our other drug candidates.
27 unchanged sentences
Risk Factors” included in our annual report on Form 10-K for the year ended December 31, 2020 as filed with the Securities and Exchange Commission.
+Added: — Certification of Principal Executive Officer Pursuant to Section 302 of the Sarbanes-Oxley Act of 2002
+Added: — Certification of Principal Financial Officer Pursuant to Section 302 of the Sarbanes-Oxley Act of 2002
+Added: — Certification of Principal Executive and Principal Financial Officers Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002
+Added: — XBRL Instance Document
+Added: — XBRL Taxonomy Extension Schema Document
+Added: — XBRL Taxonomy Extension Calculation Linkbase Document
+Added: — XBRL Taxonomy Extension Definition Linkbase Document
+Added: — XBRL Taxonomy Extension Label Linkbase Document
+Added: — XBRL Taxonomy Extension Presentation Linkbase Document
+Added: 104 — Cover Page Interactive Data File (embedded within the Inline XBRL document)
+Added: _____________________
+Added: * Filed herewith.
+Added: Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.
+Added: Lexicon Pharmaceuticals, Inc.
+Added: August 6, 2021 By:
+Added: /s/ Lonnel Coats
+Added: President and Chief Executive Officer
+Added: August 6, 2021 By:
+Added: /s/ Jeffrey L.
+Added: Executive Vice President, Corporate and Administrative Affairs and Chief Financial Officer
Compared sentence by sentence after normalising whitespace, quotation marks, case and digits, so re-formatting and restated figures do not read as changed language. Wording changes appear as one removal and one addition. The current filing and the prior one are authoritative.