1 unchanged sentence
Trading arrangements
−Removed: During the three months ended September 30, 2025 , no director or officer adopted or terminated any Rule 10b5-1 trading arrangement or any non-Rule 10b5-1 trading arrangement (as such terms are defined pursuant to Item 408(a) of Regulation S-K).
+Added: During the three months ended March 31, 2026 , no director or officer adopted or terminated any Rule 10b5-1 trading arrangement or any non-Rule 10b5-1 trading arrangement (as such terms are defined pursuant to Item 408(a) of Regulation S-K).
Amended and Restated Certificate of Incorporation (incorporated by reference to Exhibit 3.1 to the Registrant’s Current Report on Form 8-K, filed June 15, 2021).
5 unchanged sentences
Form of Pre-Funded Warrant (incorporated by reference to Exhibit 4.1 to the Registrant’s Current Report on Form 8-K, filed February 29, 2024).
−Removed: Form of Pre-Funded Warrant (incorporated by reference to Exhibit 4.1 to the Registrant’s Current Report on Form 8-K, filed with the SEC on December 5, 2024).
+Added: Amended and Restated Non-Employee Director Compensation Policy.
+Added: Employment Agreement, by and between the Registrant and William Go, M.D., Ph.D., dated January 12, 2026.
+Added: Exclusive License and Collaboration Agreement, by and between the Registrant and Bristol Myers Squibb, dated January 21, 2026.
Certification of Principal Executive and Financial Officer Pursuant to Rules 13a-14(a) and 15d-14(a) under the Securities Exchange Act of 1934, as Adopted Pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.
4 unchanged sentences
Cover Page Interactive Data File (embedded within the Inline XBRL document)
+Added: Indicates management contract or compensatory plan.
+Added: Certain portions of this exhibit are omitted because they are not material and would likely cause competitive harm to the Registrant if disclosed.
The information in Exhibit 32.1 shall not be deemed “filed” for purposes of Section 18 of the Exchange Act, or otherwise subject to the liabilities of that section, nor shall it be deemed incorporated by reference in any filing under the Securities Act or the Exchange Act (including this Quarterly Report on Form 10-Q), unless the Registrant specifically incorporates the foregoing information into those documents by reference.
1 unchanged sentence
JANUX THERAPEUTICS, INC.
−Removed: November 6, 2025
/s/ David Campbell, Ph.D.
3 unchanged sentences
Compared sentence by sentence after normalising whitespace, quotation marks, case and digits, so re-formatting and restated figures do not read as changed language. Wording changes appear as one removal and one addition. The current filing and the prior one are authoritative.