49 unchanged sentences
and the Report of the Independent Registered Public Accounting Firm are included in Part II, Item 8 of this Annual Report on Form 10-K:
−Removed: Reports of Independent Registered Public Accounting Firms (PCAOB ID:173 and 170)
+Added: Reports of Independent Registered Public Accounting Firms (PCAOB ID:
+Added: 248, 173 and 170)
Balance Sheets as of December 31, 2025 and 2024
15 unchanged sentences
(incorporated by reference to Exhibit 4.5 to the Registrant’s Annual Report on Form 10-K for the year ended December 31, 2019 filed March 5, 2020).
−Removed: Registration Rights Agreement dated June 19, 2017 by and among the Registrant and certain of its stockholders (incorporated by reference to Exhibit 10.2 to the Registrant’ s Registration Statement on Form S-1, as amended (File No.
−Removed: 333-226774), originally filed August 10, 2018).
Asset Purchase Agreement (DS-200) dated June 23, 2017 between Selenix, LLC and the Registrant (incorporated by reference to Exhibit 10.5 to the Registrant’s Registration Statement on Form S-1, as amended (File No.
333-226774), originally filed August 10, 2018).
−Removed: Amended and Restated Agreement relating to sales and marketing dated February 18, 2019 between the Registrant and Eyemax, LLC (incorporated by reference to Exhibit 10.6 to the Registrant’ s Quarterly Report on Form 10-Q for the quarter ended March 31, 2019) .
−Removed: Sales/Marketing Agreement (DS-300) dated November 17, 2017 by and among AL Pharma, Inc., SCS National, LLC, Dry Creek Project, LLC and the Registrant (incorporated by reference to Exhibit 10.9 to the Registrant’ s Registration Statement on Form S-1, as amended (File No.
−Removed: 333-226774), originally filed August 10, 2018).
−Removed: Offer Letter Agreement by and between the Registrant and Sean E.
−Removed: Brynjelsen, dated as of May 17, 2017 (incorporated by reference to Exhibit 10.12 to the Registrant’ s Registration Statement on Form S-1, as amended (File No.
−Removed: 333-226774), originally filed August 10, 2018).
−Removed: Offer Letter Agreement by and between the Registrant and James Gruber, dated as of March 25, 2022.
+Added: Amended Offer Letter Agreement by and between the Registrant and Sean E.
+Added: Brynjelsen, dated as of June 27, 2017 (incorporated by reference to Exhibit 10.1 to the Registrant’s Quarterly Report on Form 10-Q for the quarter ended June 30, 2025, filed on August 7, 2025).
+Added: Amended Offer Letter Agreement by and between the Registrant and David Krempa, dated as of June 27, 2017 (incorporated by reference to Exhibit 10.3 to the Registrant’s Quarterly Report on Form 10-Q for the quarter ended June 30, 2025, filed on August 7, 2025).
+Added: Amended Offer Letter Agreement by and between the Registrant and James Gruber, dated as of June 27, 2017 (incorporated by reference to Exhibit 10.2 to the Registrant’s Quarterly Report on Form 10-Q for the quarter ended June 30, 2025, filed on August 7, 2025).
+Added: Amended Offer Letter Agreement by and between the Registrant and Ipek Erdogan-Trinkaus, dated as of June 27, 2017 (incorporated by reference to Exhibit 10.4 to the Registrant’s Quarterly Report on Form 10-Q for the quarter ended June 30, 2025, filed on August 7, 2025).
2018 Equity Incentive Plan as amended December 2020 (incorporated by reference to Exhibit 10.11 to the Registrant’s Annual Report on Form 10-K for the year ended December 31, 2020 filed on March 16, 2021).
1 unchanged sentence
333-226774), originally filed August 10, 2018).
−Removed: Amendment No.
−Removed: 1 dated August 29, 2018 to Sales/Marketing Agreement (DS-300) dated November 17, 2017 between AL Pharma, Inc.
−Removed: and the Registrant (incorporated by reference to Exhibit 10.18 to the Registrant’ s Registration Statement on Form S-1, as amended (File No.
−Removed: 333-226774), originally filed August 10, 2018).
Credit Agreement dated as of November 13, 2019, by and among the Company and SWK Funding LLC (incorporated by reference to Exhibit 10.14 to the Registrant’s Annual Report on Form 10-K for the year ended December 31, 2019 filed March 5, 2020) (as amended on April 5, 2022 and such amendment is incorporated by reference to exhibit 10.1 to the Registrant’s quarterly report on Form 10-Q for the quarter ended March 31, 2022).
−Removed: Asset Purchase Agreement by and between the Company and Ipsen Biopharmaceuticals, Inc., dated as of October 2, 2024 (portions of the exhibit have been redacted).
+Added: Asset Purchase Agreement by and between the Company and Ipsen Biopharmaceuticals, Inc., dated as of October 2, 2024 (portions of the exhibit have been redacted)(incorporated by reference to Exhibit 10.11 to the Registrant's Annual Report on Form 10-K for the year ended December 31, 2024, filed on March 18, 2025).
Fifth Amendment to Credit Agreement by and among the Company SWK Funding LLC dated as of September 30, 2024 (incorporated by reference to Exhibit 10.1 of the Registrants Quarterly Report on Form 10-Q for the quarter ended September 30, 2024, filed on November 12, 2024).
Second Amendment to Warrant Agreement by and among the Company and SWK Funding LLC dated as of September 30, 2024 (incorporated by reference to Exhibit 10.2 of the Registrants Quarterly Report on Form 10-Q for the quarter ended September 30, 2024, filed on November 12, 2024).
−Removed: Licensing Agreement by and between the Company and AMMTek dated as of November 22, 2024.
+Added: Licensing Agreement by and between the Company and AMMTek dated as of November 22, 2024 (incorporated by reference to Exhibit 10.14 to the Registrant's Annual Report on Form 10-K for the year ended December 31, 2024, filed on March 18, 2025).
Form of Securities Purchase Agreement by and between the Company and an institutional investor dated as of December 10, 2024 (incorporated by reference to Exhibit 10.1 of the Registrant’s Current Report on Form 8-K dated December 12, 2024).
1 unchanged sentence
and the Registrant (portions of the Exhibit have been redacted) (incorporated by reference to Exhibit 10.1 of the Registrant’s Current Report on Form 8-K dated January 3, 2025).
+Added: Consent of Independent Registered Public Accounting Firm (Crowe LLP - PCAOB ID:
+Added: Consent of Independent Registered Public Accounting Firm (KMJ Corbin & Company LLP - PCAOB ID:
+Added: Consent of Independent Registered Public Accounting Firm (Grant Thornton LLP - PCAOB ID:
Insider Trading Policy (incorporated by reference to Exhibit 19.1 of the Registrant's Annual Report on Form 10-K for the year ended December 31, 2023, as filed with the SEC on March 14, 2024.
42 unchanged sentences
Compared sentence by sentence after normalising whitespace, quotation marks, case and digits, so re-formatting and restated figures do not read as changed language. Wording changes appear as one removal and one addition. The current filing and the prior one are authoritative.