What changed in this filing

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Item 1B. Unresolved Staff Comments

2025-03-28 compared with 2024-03-29 · 31 added, 21 removed, 46 unchanged (53% of the section changed)

6 unchanged sentences

measures to protect all Company stakeholders and manage third party risk.

operations may, in some cases, involve the storage, transmission and other processing of customer and research data or sales information.

Cyberattacks and other malicious internet-based activity continue to increase, and cloud-based platform providers of services are expected

to continue to be targeted.

Threats include traditional computer “hackers,” malicious code (such as viruses and worms), phishing

attacks, employee theft or misuse and denial-of-service attacks, and use of artificial intelligence.

We have not experienced cyberattacks

in the past, and there can be no guarantee that in the future such cyberattacks will not be material.

We maintain an information security

program that is comprised of policies and controls designed to mitigate cybersecurity risk.

However, at any given time, we face known

and unknown cybersecurity risks and threats that are not fully mitigated, and we continuously work to enhance our information security

program and risk management efforts.

Our operations may, in some cases, involve the

storage, transmission and other processing of customer and research data or sales information.

Cyberattacks and other malicious internet-based

activity continue to increase, and cloud-based platform providers of services are expected to continue to be targeted.

Threats include

traditional computer “hackers,” malicious code (such as viruses and worms), phishing attacks, employee theft or misuse and

denial-of-service attacks, and use of artificial intelligence.

We have not experienced cyberattacks in the past, and there can be no guarantee

that in the future such cyberattacks will not be material.

We maintain an information security program that is comprised of policies and

controls designed to mitigate cybersecurity risk.

However, at any given time, we face known and unknown cybersecurity risks and threats

that are not fully mitigated, and we continuously work to enhance our information security program and risk management efforts.

cybersecurity incidents could have material adverse effects on our business strategy, financial condition, and results of operations (e.g.,

a significant breach could result in direct financial losses due to fraud, system downtime impacting revenue generation, increased compliance

costs or contractual liabilities with third-party vendors and customers).

on the environment and system, we implement and maintain various technical, physical, and organizational measures, processes, standards

9 unchanged sentences

and cybersecurity.

In addition, the Board will oversee any cybersecurity

risk management framework and a dedicated committee of the Board or an officer appointed by the Board will review and approve any cybersecurity

policies, strategies and risk management practices.

The Board (or designated committee or officer) will receive periodic updates on cybersecurity

risks, including emerging threats, mitigation efforts and incident response activities.

The updates will be provided at least annually,

or more frequently as needed, to ensure cybersecurity risks are appropriately managed and integrated into our broader risk oversight strategy.

Cybersecurity

11 unchanged sentences

data breach notification, information security and data privacy requirements.

We expect this trend of state-level activity in those

areas to continue and are continually monitoring developments where our customers are located.

We expect this trend of state-level activity in those areas

to continue and are continually monitoring developments where our customers are located.

and exposures related to cybersecurity attacks, including litigation and enforcement risks, are expected to be elevated for the foreseeable

10 unchanged sentences

cannot provide assurance that we will not experience any such event in the future.

a description of the risks from cybersecurity threats that may materially affect the Company and how they may do so, see our risk factors

under Part 1.

Risk Factors in this Annual Report on Form 10-K, including the risk entitled “Our computer systems or data,

or those of our collaborators or other contractors or consultants, maybe compromised, which could result in adverse consequences, including

but not limited to regulatory investigations or actions;

For a description of the risks from cybersecurity

threats that may materially affect the Company and how they may do so, see our risk factors under Part 1.

Risk Factors in this

Annual Report, including the risk entitled “Our computer systems or data, or those of our collaborators or other contractors or

consultants, maybe compromised, which could result in adverse consequences, including but not limited to regulatory investigations or

fines and penalties;

significant disruption of our product development

programs and our ability to operate our business effectively;

significant disruption of our product development programs and our ability to operate our business

reputational harm;

1 unchanged sentence

Compared sentence by sentence after normalising whitespace, quotation marks, case and digits, so re-formatting and restated figures do not read as changed language. Wording changes appear as one removal and one addition. The current filing and the prior one are authoritative.

What changed 10-K

Item 1B. Unresolved Staff Comments