What changed in this filing

/stocks — the workspaceLOADING

Item 1B. Unresolved Staff Comments

2026-03-30 compared with 2025-03-31 · 23 added, 21 removed, 26 unchanged (63% of the section changed)

4 unchanged sentences

or vendors, violation of privacy laws and other litigations, legal and reputational risk.

The Company acknowledges that an actual or perceived

breach of its information assets could damage its reputation, interfere with the progress of clinical trials, or interfere with efforts

to pursue regulatory approvals for its product candidates.

The Company also recognizes that an actual or perceived breach of its information

assets could impact the Company’s business strategy, operations, or financial condition, as well as subject Actinium to third–party

lawsuits, regulatory fines or other actions or liabilities, any of which could adversely affect the Company.

For further information,

see “Risk Factors—Our business is subject to cybersecurity risks” in Item 1A of this Annual Report on Form 10–K.

Company acknowledges that an actual or perceived breach of its information assets could damage its reputation, interfere with the progress

of clinical trials, or interfere with efforts to pursue regulatory approvals for its product candidates.

The Company also recognizes

that an actual or perceived breach of its information assets could impact the Company’s business strategy, operations, or financial

condition, as well as subject Actinium to third–party lawsuits, regulatory fines or other actions or liabilities, any of which

could adversely affect the Company.

For further information, see “Risk Factors—Our business is subject to cybersecurity risks”

in Item 1A of this Annual Report on Form 10–K.

Risk Management Strategy:

7 unchanged sentences

and operating technical security management activities including threat, vulnerability, and network security management.

Company has established an Incident Response Policy and recovery plans to address its response to a cybersecurity incident, and such

plans are tested and evaluated on a regular basis.

This includes continuous security operation centers monitoring of the Company’s

systems and accounts.

The Company has established an Incident Response Policy and recovery

plans to address its response to a cybersecurity incident, including those related to the third-party service providers engaged by the

Company and such plans are tested and evaluated on a regular basis.

This includes continuous security operation centers monitoring of

the Company’s systems and accounts.

Company proactively mitigates its financial exposure to cybersecurity incidents by maintaining a cyber liability insurance policy.

4 unchanged sentences

date, Actinium has not experienced any material cybersecurity incident that affected the Company’s operations or financial condition.

rely on a multidisciplinary team including third-party service providers to assess how identified cybersecurity threats could impact

our business.

The Company’s cybersecurity function is managed by the Company’s Chief Financial Officer, who assumes the overall

responsibility and accountability of the function and with select members of the Company’s management is collectively responsible

for the day–to–day assessment and management of cybersecurity risks, their prevention, mitigation, detection, and remediation.

Our Chief Financial Officer and other members of management have undergone various briefings from our cybersecurity advisory firm to

prepare them to effectively assess and manage material risks from cybersecurity threats.

Additionally, members of the third-party service

providers have cybersecurity experience and/or certifications.

We rely on a multidisciplinary team including third-party service providers

to assess how identified cybersecurity threats could impact our business.

The Company’s cybersecurity function is managed by the

Company’s Principal Financial Officer, who assumes the overall responsibility and accountability of the function and with select

members of the Company’s management is collectively responsible for the day–to–day assessment and management of cybersecurity

risks, their prevention, mitigation, detection, and remediation.

Our Principal Financial Officer and other members of management have

undergone various briefings from our cybersecurity advisory firm to prepare them to effectively assess and manage material risks from

cybersecurity threats.

Additionally, members of the third-party service providers have cybersecurity experience and/or certifications.

Company’s Board is involved in overseeing our risk management processes and policies that may be implemented from time to time.

5 unchanged sentences

Compared sentence by sentence after normalising whitespace, quotation marks, case and digits, so re-formatting and restated figures do not read as changed language. Wording changes appear as one removal and one addition. The current filing and the prior one are authoritative.

What changed 10-K

Item 1B. Unresolved Staff Comments