What changed in this filing

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Item 9A. Controls and Procedures

2021-03-05 compared with 2020-03-06 · 166 added, 195 removed, 120 unchanged (75% of the section changed)

1 unchanged sentence

Evaluation of disclosure controls and procedures.

As required by Rule 13a-15 under the

Securities Exchange Act of 1934 (“Exchange Act”), we carried out an evaluation under the supervision and with the participation

of our management, including our chief executive officer and chief financial officer, of the effectiveness of the design and operation

of our disclosure controls and procedures as of the end of the period covered by this report.

Based upon that evaluation, the chief

executive officer and chief financial officer have concluded that our disclosure controls and procedures are effective as of December

31, 2019 to ensure that information required to be disclosed by us in reports we file or submit under the Exchange Act is recorded,

processed, summarized, and reported within the time periods specified in SEC rules and forms.

Disclosure controls and procedures

include, without limitation, controls and procedures designed to ensure that information required to be disclosed by our company

in the reports we file or submit under the Exchange Act is accumulated and communicated to our management, including our chief

executive officer and chief financial officer, or persons performing similar functions, as appropriate to allow timely decisions

regarding required disclosure.

On an on-going basis, we review and document our disclosure controls and procedures, and our internal

control over financial reporting, and we may from time to time make changes aimed at enhancing their effectiveness and ensuring

that our systems evolve with our business.

As required by Rule 13a-15 under the Securities Exchange Act of 1934, or the Exchange Act, we carried out an evaluation under the supervision and with the participation of our management, including our chief executive officer and chief financial officer, of the effectiveness of the design and operation of our disclosure controls and procedures as of the end of the period covered by this report.

Based upon that evaluation, the chief executive officer and chief financial officer have concluded that our disclosure controls and procedures are effective as of December 31, 2020 to ensure that information required to be disclosed by us in reports we file or submit under the Exchange Act is recorded, processed, summarized, and reported within the time periods specified in SEC rules and forms.

Disclosure controls and procedures include, without limitation, controls and procedures designed to ensure that information required to be disclosed by our company in the reports we file or submit under the Exchange Act is accumulated and communicated to our management, including our chief executive officer and chief financial officer, or persons performing similar functions, as appropriate to allow timely decisions regarding required disclosure.

On an on-going basis, we review and document our disclosure controls and procedures, and our internal control over financial reporting, and we may from time to time make changes aimed at enhancing their effectiveness and ensuring that our systems evolve with our business.

Changes in internal controls over financial reporting.

There were no changes in our internal control

over financial reporting during the quarter ended December 31, 2019 that have materially affected, or that are reasonably likely

to materially affect, our internal controls over financial reporting.

Management’s Report on Internal

Control over Financial Reporting

Our management is responsible for establishing

and maintaining adequate internal control over financial reporting as defined in Rules 13a-15(f) and 15d-15(f) under the Exchange

Our internal control over financial reporting is a process designed to provide reasonable assurance regarding the reliability

of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted

accounting principles in the United States.

Because of its inherent limitations, internal

control over financial reporting can provide only reasonable assurance, and it may not prevent or detect misstatements.

Also, projections

of any evaluation of effectiveness to future periods are subject to the risk that controls may become inadequate because of changes

in conditions or that the degree of compliance with the policies or procedures may deteriorate.

Our management assessed the effectiveness

of our internal control over financial reporting as of December 31, 2019.

In making this assessment, management used the criteria

set forth by the Committee of Sponsoring Organizations of the Treadway Commission in its 2013 Internal Control—Integrated

Based on its assessment and those criteria,

our management believes that our company maintained effective internal control over financial reporting as of December 31,

The effectiveness of our internal control

over financial reporting as of December 31, 2019 has been audited by Deloitte & Touche LLP an independent registered

public accounting firm, as stated in their report which is included below in this Item 9A of this annual report on Form 10-K.

REPORT OF INDEPENDENT REGISTERED PUBLIC

ACCOUNTING FIRM

To the Board of Directors and Stockholders

of Anika Therapeutics, Inc.

Opinion on Internal Control over Financial

We have audited the internal control over financial reporting of

Anika Therapeutics, Inc.

and subsidiaries (the “Company”) as of December 31, 2019, based on criteria established in

Internal Control —

Integrated Framework (2013) issued by the Committee of Sponsoring Organizations of the Treadway

Commission (COSO).

In our opinion, the Company maintained, in all material respects, effective internal control over financial

reporting as of December 31, 2019, based on criteria established in Internal Control —

Integrated Framework (2013)

issued by COSO.

We have also audited, in accordance with the standards of the

Public Company Accounting Oversight Board (United States) (PCAOB), the consolidated financial statements as of and for the year

ended December 31, 2019, of the Company and our report dated March 5, 2020, expressed an unqualified opinion on those financial

statements and included an explanatory paragraph related to the Company’s change in method of accounting for leases in fiscal

year 2019 due to the adoption of the new lease standard.

We are finalizing the process of integrating our acquisition of Parcus Medical and Arthrosurface, including evaluating our internal controls, and designing and implementing an internal control structure over Parcus Medical and Arthrosurface’s operations, which will be complete in the first quarter of 2021.

During the year ended December 31, 2020 we implemented controls over the accounting and disclosures related to purchase accounting and integration of the Parcus Medical and Arthrosurface businesses, as well as enhanced controls surrounding the goodwill impairment assessment.

As a result of the COVID-19 pandemic, certain employees began working remotely in March 2020.

Additionally, we have enhanced existing controls by implementing more frequent forecasting and increasing board oversight.

We are continually monitoring and assessing the COVID-19 situation to determine any potential impact on the design and operating effectiveness of our internal controls over financial reporting.

There were no other material changes in our internal control over financial reporting during the year ended December 31, 2020, that have materially affected, or were reasonably likely to materially affect, our internal control over financial reporting.

Management’s Report on Internal Control over Financial Reporting

Our management is responsible for establishing and maintaining adequate internal control over financial reporting as defined in Rules 13a-15(f) and 15d-15(f) under the Exchange Act.

Our internal control over financial reporting is a process designed to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles in the United States.

Because of its inherent limitations, internal control over financial reporting can provide only reasonable assurance, and it may not prevent or detect misstatements.

Also, projections of any evaluation of effectiveness to future periods are subject to the risk that controls may become inadequate because of changes in conditions or that the degree of compliance with the policies or procedures may deteriorate.

Our management assessed the effectiveness of our internal control over financial reporting as of December 31, 2020.

In making this assessment, management used the criteria set forth by the Committee of Sponsoring Organizations of the Treadway Commission in its 2013 Internal Control—Integrated Framework .

Based on its assessment and those criteria, our management believes that our company maintained effective internal control over financial reporting as of December 31, 2020.

The foregoing assessment excludes certain elements of Parcus Medical and Arthrosurface’s internal control over financial reporting because they were acquired by the Company in a business combination on January 24, 2020 and February 3, 2020, respectively (see Note 3 –

Business Combinations in the Notes to Consolidated Financial Statements for additional information).

Subsequent to the acquisition, certain elements of Parcus Medical and Arthrosurface’s internal control over financial reporting and related processes were integrated into the Company’s existing systems and internal control over financial reporting.

Those controls that were not integrated have been excluded from our assessment of the effectiveness of internal control over financial reporting as of December 31, 2020.

This exclusion is in accordance with the general guidance issued by the Staff of the SEC that an assessment of a recent business acquisition may be omitted from management’s report on internal control over financial reporting in the first year of consolidation.

The exclusion represents controls covering approximately 14% of consolidated assets and 27% of consolidated revenues.

The effectiveness of our internal control over financial reporting as of December 31, 2020 has been audited by Deloitte & Touche LLP, an independent registered public accounting firm, as stated in their report which is included below in this Item 9A of this annual report on Form 10-K.

REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

To the Board of Directors and Stockholders of Anika Therapeutics, Inc.

Opinion on Internal Control over Financial Reporting

We have audited the internal control over financial reporting of Anika Therapeutics, Inc.

and subsidiaries (the “Company”) as of December 31, 2020, based on criteria established in Internal Control —

Integrated Framework (2013) issued by the Committee of Sponsoring Organizations of the Treadway Commission (COSO).

In our opinion, the Company maintained, in all material respects, effective internal control over financial reporting as of December 31, 2020, based on criteria established in Internal Control —

Integrated Framework (2013) issued by COSO.

We have also audited, in accordance with the standards of the Public Company Accounting Oversight Board (United States) (PCAOB), the consolidated financial statements as of and for the year ended December 31, 2020, of the Company and our report dated March 5, 2021, expressed an unqualified opinion on those financial statements.

As described in Management’s Report on Internal Control over Financial Reporting , management excluded from its assessment the internal control over financial reporting at Parcus Medical, LLC acquired on January 24, 2020 and Arthrosurface, Inc.

acquired on February 3, 2020, and whose combined financial statements constitute 14% of total assets (excluding goodwill and intangibles, which are included within the scope assessment) and 27% of revenues of the consolidated financial statement amounts as of and for the year ended December 31, 2020.

Accordingly, our audit did not include the internal control over financial reporting at Parcus Medical, LLC and Arthrosurface, Inc.

Basis for Opinion

The Company’s management is responsible

for maintaining effective internal control over financial reporting and for its assessment of the effectiveness of internal control

over financial reporting, included in the accompanying Management's Annual Report on Internal Control over Financial Reporting.

Our responsibility is to express an opinion on the Company’s internal control over financial reporting based on our audit.

We are a public accounting firm registered with the PCAOB and are required to be independent with respect to the Company in accordance

with the U.S.

federal securities laws and the applicable rules and regulations of the Securities and Exchange Commission and the

We conducted our audit in accordance with the standards of the

Those standards require that we plan and perform the audit to obtain reasonable assurance about whether effective internal

control over financial reporting was maintained in all material respects.

Our audit included obtaining an understanding of internal

control over financial reporting, assessing the risk that a material weakness exists, testing and evaluating the design and operating

effectiveness of internal control based on the assessed risk, and performing such other procedures as we considered necessary in

the circumstances.

The Company’s management is responsible for maintaining effective internal control over financial reporting and for its assessment of the effectiveness of internal control over financial reporting, included in the accompanying Management's Report on Internal Control over Financial Reporting .

Our responsibility is to express an opinion on the Company’s internal control over financial reporting based on our audit.

We are a public accounting firm registered with the PCAOB and are required to be independent with respect to the Company in accordance with the U.S.

federal securities laws and the applicable rules and regulations of the Securities and Exchange Commission and the PCAOB.

We conducted our audit in accordance with the standards of the PCAOB.

Those standards require that we plan and perform the audit to obtain reasonable assurance about whether effective internal control over financial reporting was maintained in all material respects.

Our audit included obtaining an understanding of internal control over financial reporting, assessing the risk that a material weakness exists, testing and evaluating the design and operating effectiveness of internal control based on the assessed risk, and performing such other procedures as we considered necessary in the circumstances.

We believe that our audit provides a reasonable basis for our opinion.

Definition and Limitations of Internal

Control over Financial Reporting

A company’s internal control over

financial reporting is a process designed to provide reasonable assurance regarding the reliability of financial reporting and

the preparation of financial statements for external purposes in accordance with generally accepted accounting principles.

internal control over financial reporting includes those policies and procedures that (1) pertain to the maintenance of records

that, in reasonable detail, accurately and fairly reflect the transactions and dispositions of the assets of the company;

reasonable assurance that transactions are recorded as necessary to permit preparation of financial statements in accordance with

generally accepted accounting principles, and that receipts and expenditures of the company are being made only in accordance with

authorizations of management and directors of the company;

and (3) provide reasonable assurance regarding prevention or timely

detection of unauthorized acquisition, use, or disposition of the company’s assets that could have a material effect on the

financial statements.

Because of its inherent limitations, internal control over financial

reporting may not prevent or detect misstatements.

Also, projections of any evaluation of effectiveness to future periods are subject

to the risk that controls may become inadequate because of changes in conditions, or that the degree of compliance with the policies

or procedures may deteriorate.

/s/ Deloitte & Touche LLP

Definition and Limitations of Internal Control over Financial Reporting

A company’s internal control over financial reporting is a process designed to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles.

A company’s internal control over financial reporting includes those policies and procedures that (1) pertain to the maintenance of records that, in reasonable detail, accurately and fairly reflect the transactions and dispositions of the assets of the company;

(2) provide reasonable assurance that transactions are recorded as necessary to permit preparation of financial statements in accordance with generally accepted accounting principles, and that receipts and expenditures of the company are being made only in accordance with authorizations of management and directors of the company;

and (3) provide reasonable assurance regarding prevention or timely detection of unauthorized acquisition, use, or disposition of the company’s assets that could have a material effect on the financial statements.

Because of its inherent limitations, internal control over financial reporting may not prevent or detect misstatements.

Also, projections of any evaluation of effectiveness to future periods are subject to the risk that controls may become inadequate because of changes in conditions, or that the degree of compliance with the policies or procedures may deteriorate.

Boston, Massachusetts

1 unchanged sentence

DIRECTORS, EXECUTIVE OFFICERS AND CORPORATE GOVERNANCE

The information required under this item

is incorporated herein by reference to our definitive proxy statement pursuant to Regulation 14A, which proxy statement will

be filed with the SEC not later than 120 days after the close of our fiscal year ended December 31, 2019.

The information required under this item is incorporated herein by reference to our definitive proxy statement pursuant to Regulation 14A, which proxy statement will be filed with the SEC not later than 120 days after the close of our fiscal year ended December 31, 2020.

EXECUTIVE COMPENSATION

The information required under this item

is incorporated herein by reference to our definitive proxy statement pursuant to Regulation 14A, which proxy statement will

be filed with the SEC not later than 120 days after the close of our fiscal year ended December 31, 2019.

SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS

AND MANAGEMENT AND RELATED STOCKHOLDER MATTERS

The information required under this item

and Item 5 of this Annual Report on Form 10-K under the heading “Equity Compensation Plan Information” is

incorporated herein by reference to our definitive proxy statement pursuant to Regulation 14A, which proxy statement will

be filed with the SEC not later than 120 days after the close of our fiscal year ended December 31, 2019.

CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS,

AND DIRECTOR INDEPENDENCE

The information required under this item

is incorporated herein by reference to our definitive proxy statement pursuant to Regulation 14A, which proxy statement will

be filed with the SEC not later than 120 days after the close of our fiscal year ended December 31, 2019.

SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT AND RELATED STOCKHOLDER MATTERS

The information required under this item and Item 5 of this Annual Report on Form 10-K under the heading “Equity Compensation Plan Information”

is incorporated herein by reference to our definitive proxy statement pursuant to Regulation 14A, which proxy statement will be filed with the SEC not later than 120 days after the close of our fiscal year ended December 31, 2020.

CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS, AND DIRECTOR INDEPENDENCE

PRINCIPAL ACCOUNTING FEES AND SERVICES

The information required under this item

is incorporated herein by reference to our definitive proxy statement pursuant to Regulation 14A, which proxy statement will

be filed with the SEC not later than 120 days after the close of our fiscal year ended December 31, 2019.

EXHIBITS AND FINANCIAL STATEMENT SCHEDULES

Documents filed as part of Form 10-K.

(1) Financial Statements

Documents filed as part of Form 10-K.

(1)            Financial Statements

Report of Independent Registered Public Accounting Firm

1 unchanged sentence

Consolidated Statements of Operations and Comprehensive Income

Consolidated Statements of Stockholders’ Equity

Consolidated Statements of Stockholders’

Consolidated Statements of Cash Flows

Notes to Consolidated Financial Statements

(2) Schedules

Schedules have

been omitted as all required information has been disclosed in the financial statements and related footnotes.

(2)            Schedules

 Schedules have been omitted as all required information has been disclosed in the financial statements and related footnotes. 

(3)            Exhibits

Agreement and Plan of Merger, dated January 4, 2020, by and between Anika Therapeutics, Inc., Arthrosurface, Inc., Button Merger Sub, Inc.

1 unchanged sentence

Agreement and Plan of Merger, dated January 4, 2020, by and between Anika Therapeutics, Inc., Parcus Medical, LLC, Sunshine Merger Sub, LLC and Philip Mundy

of Incorporation of Anika Therapeutics, Inc.

of Anika Therapeutics, Inc., effective as of June 6, 2018

dated January 3, 2007, between Anika Therapeutics, Inc.

and Farley White Wiggins, LLC, relating to 32 Wiggins Avenue, Bedford,

Massachusetts

Certificate of Incorporation of Anika Therapeutics, Inc.

Bylaws of Anika Therapeutics, Inc., effective as of June 6, 2018

Lease, dated January 3, 2007, between Anika Therapeutics, Inc.

and Farley White Wiggins, LLC, relating to 32 Wiggins Avenue, Bedford, Massachusetts

Amendment No.

1 to Lease, dated February 1, 2007, between Anika Therapeutics, Inc.

and Farley White Wiggins, LLC, relating to 32 Wiggins

Avenue, Bedford, Massachusetts

Agreement, dated December 30, 2009, between Fidia Farmaceutici S.p.A.

and Fidia Advanced Biopolymers S.r.l., relating to Via

Ponte della Fabbrica 3/A and 3/B Abano Terme, Padua, Italy

and Farley White Wiggins, LLC, relating to 32 Wiggins Avenue, Bedford, Massachusetts

Lease Agreement, dated December 30, 2009, between Fidia Farmaceutici S.p.A.

and Fidia Advanced Biopolymers S.r.l., relating to Via Ponte della Fabbrica 3/A and 3/B Abano Terme, Padua, Italy

Amendment No.

1 to Lease Agreement, dated June 18, 2010, between Fidia Farmaceutici S.p.A.

and Anika Therapeutics S.r.l.

(formerly Fidia

Advanced Biopolymers S.r.l.) relating to Via Ponte Della Fabbrica 3/A and 3/B Abano Terme, Padua, Italy

(formerly Fidia Advanced Biopolymers S.r.l.) relating to Via Ponte Della Fabbrica 3/A and 3/B Abano Terme, Padua, Italy

Amendment No.

2 to Lease Agreement, dated September 20, 2010, between Fidia Farmaceutici S.p.A.

and Anika Therapeutics S.r.l.

Fidia Advanced Biopolymers S.r.l.) relating to Via Ponte Della Fabbrica 3/A and 3/B Abano Terme, Padua, Italy

of Amendment No.

(formerly Fidia Advanced Biopolymers S.r.l.) relating to Via Ponte Della Fabbrica 3/A and 3/B Abano Terme, Padua, Italy

Translation of Amendment No.

3 to Lease Agreement, dated April 16, 2012, between Fidia Farmaceutici S.p.A.

1 unchanged sentence

(formerly Fidia Advanced Biopolymers S.r.l.) relating to Via Ponte Della Fabbrica 3/A and 3/B Abano Terme, Padua, Italy

of Amendment No.

Translation of Amendment No.

4 to Lease Agreement, dated February 22, 2016, between Fidia Farmaceutici S.p.A.

1 unchanged sentence

(formerly Fidia Advanced Biopolymers S.r.l.) relating to Via Ponte Della Fabbrica 3/A and 3/B Abano Terme, Padua, Italy

of Lease Agreement, dated October 9, 2015, between Anika Therapeutics S.r.l.

and Consorzio Zona Industriale E Porto Fluviale

di Padova relating to Land Registry of the Municipality of Padova, Page 148, cadastral map 516 and 517

of Amendment No.

Translation of Lease Agreement, dated October 9, 2015, between Anika Therapeutics S.r.l.

and Consorzio Zona Industriale E Porto Fluviale di Padova relating to Land Registry of the Municipality of Padova, Page 148, cadastral map 516 and 517

Translation of Amendment No.

1 to Lease Agreement, dated February 2, 2017, between Anika Therapeutics S.r.l.

and Consorzio Zona Industriale

E Porto Fluviale di Padova relating to Land Registry of the Municipality of Padova, Page 148, cadastral map 516 and 517

Agreement, dated as of October 24, 2017, among Anika Therapeutics, Inc., certain subsidiaries of Anika Therapeutics, Inc.

as are or may from time to time become parties to the Credit Agreement, Bank of America, N.A., as administrative agent, swingline

lender and issuer of letters of credit, and the lenders party thereto.

and Pledge Agreement, dated as of October 24, 2017, among Anika Therapeutics, Inc., certain subsidiaries of Anika Therapeutics,

and Consorzio Zona Industriale E Porto Fluviale di Padova relating to Land Registry of the Municipality of Padova, Page 148, cadastral map 516 and 517

Credit Agreement, dated as of October 24, 2017, among Anika Therapeutics, Inc., certain subsidiaries of Anika Therapeutics, Inc.

as are or may from time to time become parties to the Credit Agreement, Bank of America, N.A., as administrative agent, swingline lender and issuer of letters of credit, and the lenders party thereto.

Security and Pledge Agreement, dated as of October 24, 2017, among Anika Therapeutics, Inc., certain subsidiaries of Anika Therapeutics, Inc.

listed on the signature pages thereto, and Bank of America, N.A., as administrative agent.

and Purchase Agreement, dated December 30, 2009, by and between Fidia Farmaceutici S.p.A.

First Amendment effective August 13, 2019, with respect to the Credit Agreement dated as of October 24, 2017 and the Security and Pledge Agreement dated as of October 24, 2017

Second Amendment effective May 14, 2020, with respect to the Credit Agreement dated as of October 24, 2017 and the Security and Pledge Agreement dated as of October 24, 2017

Sale and Purchase Agreement, dated December 30, 2009, by and between Fidia Farmaceutici S.p.A.

and Anika Therapeutics, Inc.

Agreement, dated December 30, 2009, between Fidia Farmaceutici S.p.A.

Tolling Agreement, dated December 30, 2009, between Fidia Farmaceutici S.p.A.

and Fidia Advanced Biopolymers S.r.l.

Amendment No.

1 to Tolling Agreement, dated January 1, 2012, between Fidia Farmaceutici S.p.A.

and Anika Therapeutics S.r.l.

Fidia Advanced Biopolymers S.r.l.)

Rights Agreement, dated December 30, 2009, between Anika Therapeutics, Inc.

(formerly Fidia Advanced Biopolymers S.r.l.) 

Registration Rights Agreement, dated December 30, 2009, between Anika Therapeutics, Inc.

and Fidia Farmaceutici S.p.A.

Agreement, dated as of December 20, 2003, by and between Anika Therapeutics, Inc.

License Agreement, dated as of December 20, 2003, by and between Anika Therapeutics, Inc.

and Ortho Biotech Products, L.P.

Agreement, dated as of December 21, 2011, by and between Anika Therapeutics, Inc.

License Agreement, dated as of December 21, 2011, by and between Anika Therapeutics, Inc.

and DePuy Mitek, Inc.

Therapeutics, Inc.

†10.10

Anika Therapeutics, Inc.

Senior Executive Incentive Compensation Plan

Therapeutics, Inc.

†10.11

Anika Therapeutics, Inc.

Non-Employee Director Compensation Policy

Amended and Restated 2003 Stock Option and Incentive Plan (adopted April 5, 2011)

to Second Amended and Restated 2003 Stock Option and Incentive Plan (adopted April 11, 2013)

Form of Incentive Stock Option Agreement under Second Amended and Restated 2003 Stock Option and Incentive Plan

†10.12a

Second Amended and Restated 2003 Stock Option and Incentive Plan (adopted April 5, 2011)

†10.12b

Amendment to Second Amended and Restated 2003 Stock Option and Incentive Plan (adopted April 11, 2013)

†10.12c

Form of Incentive Stock Option Agreement under Second Amended and Restated 2003 Stock Option and Incentive Plan  

†10.12d

Form of Non-Qualified Stock Option Agreement for Non-Employee Directors under Second Amended and Restated 2003 Stock Option and Incentive Plan

†10.13a

Anika Therapeutics, Inc.

2017 Omnibus Incentive Plan

†10.13b

Anika Therapeutics, Inc.

2017 Omnibus Incentive Plan (as amended effective June 18, 2019)

†10.13c

Anika Therapeutics, Inc.

2017 Omnibus Incentive Plan (as amended effective June 16, 2020)

†10.13d

Form of Notice of Grant of Incentive Stock Option, including Terms and Conditions of Stock Option, granted under Anika Therapeutics, Inc.

2017 Omnibus Incentive Plan.

†10.13e

Form of Notice of Grant of Nonqualified Stock Option, including Terms and Conditions of Stock Option, granted under Anika Therapeutics, Inc.

2017 Omnibus Incentive Plan

†10.13f

Form of Notice of Grant of Restricted Stock Award, including Terms and Conditions of Restricted Stock Award, granted under Anika Therapeutics, Inc.

2017 Omnibus Incentive Plan.

†10.13g

Form of Notice of Grant of Restricted Stock Units, including Terms and Conditions of Restricted Stock Units, granted under Anika Therapeutics, Inc.

2017 Omnibus Incentive Plan

Form of Notice of Grant of Deferred Stock AwardsUnits, including Terms and Conditions of Deferred Stock Units, granted under Anika Therapeutics, Inc.

†10.13h

Form of Notice of Grant of Deferred Stock Awards Units, including Terms and Conditions of Deferred Stock Units, granted under Anika Therapeutics, Inc.

2017 Omnibus Incentive Plan

†10.14a

Employment Agreement, dated February 25, 2020, by and between Anika Therapeutics, Inc., and Dr.

†10.14b

Employment Agreement, dated April 23, 2020, by and between Anika Therapeutics, Inc., and Dr.

†10.15

Offer letter dated as of July 29, 2020 between Anika Therapeutics, Inc.

and Michael Levitz

†10.16a

Employment Agreement, dated July 27, 2017, by and between Anika Therapeutics, Inc.

and Joseph Darling

†10.16b

Amendment No.

1 unchanged sentence

and Joseph G.

†10.16c

Amendment No.

1 unchanged sentence

and Joseph G.

†10.17a

Employment Agreement, dated March 22, 2010, between Anika Therapeutics, Inc.

and Sylvia Cheung

†10.17b

Amendment No.

1 unchanged sentence

and Sylvia Cheung

†10.17c

Amendment No.

1 unchanged sentence

and Sylvia Cheung

†10.18a

Employment Agreement, dated September 10, 2009, between Anika Therapeutics, Inc.

†10.18b

Amendment No.

1 to Employment Agreement, dated December 1, 2010, by and between Anika Therapeutics, Inc.

†10.19a

Employment Agreement, dated October 17, 2008, between Anika Therapeutics, Inc.

1 unchanged sentence

Sherwood, Ph.D.

†10.19b

Amendment No.

5 unchanged sentences

Sherwood, Ph.D., dated March 8, 2018

†10.21

Executive Retention Agreement, dated April 9, 2019, by and between Anika Therapeutics, Inc.

and Thomas Finnerty

†10.22

Separation Agreement, effective July 8, 2019, by and between Anika Therapeutics, Inc.

8 unchanged sentences

Consent of Deloitte & Touche LLP

Certification of Principal Executive Officer

pursuant to Section 302 of the Sarbanes-Oxley Act of 2002

Certification of Principal Financial Officer

pursuant to Section 302 of the Sarbanes-Oxley Act of 2002

Certification of Principal Executive Officer pursuant to Section 302 of the Sarbanes-Oxley Act of 2002

Certification of Principal Financial Officer pursuant to Section 302 of the Sarbanes-Oxley Act of 2002

Certification pursuant to 18 U.S.C.

1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002

The following materials from the Annual Report

on Form 10-K of Anika Therapeutics, Inc.

for the fiscal year ended December 31, 2019, formatted in XBRL:

(i) Consolidated

Balance Sheets as of December 31, 2019 and December 31, 2018;

(ii) Consolidated Statements of Operations and Comprehensive

Income for the Years Ended December 31, 2019, December 31, 2018, and December 31, 2017;

(iii) Consolidated Statements of Stockholders’

Equity for the Years Ended December 31, 2019, December 31, 2018, and December 31, 2017;

(iv) Consolidated Statements

of Cash Flows for the Years Ended December 31, 2019, December 31, 2018, and December 31, 2017;

and (v) Notes to Consolidated

Financial Statements

Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002

The following materials from the Annual Report on Form 10-K of Anika Therapeutics, Inc.

for the fiscal year ended December 31, 2019, formatted in Inline XBRL:  (i) Consolidated Balance Sheets as of December 31, 2019 and December 31, 2018;

(ii) Consolidated Statements of Operations and Comprehensive Income for the Years Ended December 31, 2019, December 31, 2018, and December 31, 2017;

(iii) Consolidated Statements of Stockholders’

Equity for the Years Ended December 31, 2019, December 31, 2018, and December 31, 2017;

(iv) Consolidated Statements of Cash Flows for the Years Ended December 31, 2019, December 31, 2018, and December 31, 2017;

and (v) Notes to Consolidated Financial Statements

Cover Page Interactive Data File (formatted as Inline XBRL and contained in Exhibit 101)

Portions of this exhibit have been redacted in compliance with Regulation S-K Item 601(b)(2).

The omitted information is not

material and would likely cause competitive harm to the Company if publicly disclosed.

The omitted information is not material and would likely cause competitive harm to the Company if publicly disclosed.

Management contract or compensatory plan or arrangement.

3 unchanged sentences

under the Securities Act of 1933 or the Securities Exchange Act of 1934, whether made before or after the date of this Form 10-K, irrespective of any general incorporation language contained in such filing.

Pursuant to Rule 406T of Regulation S-T, XBRL (Extensible Business Reporting Language) information is deemed not filed or a part of a registration statement or prospectus for purposes of sections 11 or 12 of the Securities Act of 1933, is deemed not filed for purposes of section 18 of the Securities Exchange Act of 1934 and otherwise is not subject to liability under these sections.

Pursuant to the requirements

of Section 13 or 15(d) of the Securities Exchange Act of 1934, as amended, the registrant has duly caused this report to be

signed on its behalf by the undersigned, thereunto duly authorized.

ANIKA THERAPEUTICS, INC.

Pursuant to Rule 406T of Regulation S-T, XBRL (Extensible Business Reporting Language) information is deemed not filed or a part of a registration statement or prospectus for purposes of sections 11 or 12 of the Securities Act of 1933, is deemed not filed for purposes of section 18 of the Securities Exchange Act of 1934 and otherwise is not subject to liability under these sections.

Pursuant to the requirements of Section 13 or 15(d) of the Securities Exchange Act of 1934, as amended, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

ANIKA THERAPEUTICS, INC.

March 5, 2021

CHERYL BLANCHARD

Cheryl Blanchard

/s/ CHERYL BLANCHARD

Blanchard, Ph.D.

Chief Executive Officer

Pursuant to the requirements of the Securities

Exchange Act of 1934, this report has been signed below by the following persons on behalf of the registrant and in the capacities

and on the dates indicated.

Pursuant to the requirements of the Securities Exchange Act of 1934, this report has been signed below by the following persons on behalf of the registrant and in the capacities and on the dates indicated.

/s/ CHERYL BLANCHARD

Interim Chief Executive Officer

Cheryl Blanchard

Chief Executive Officer

Blanchard, Ph.D.

( Principle Executive Officer )

March 5, 2021

/s/ SYLVIA CHEUNG

/s/ MICHAEL LEVITZ

Chief Financial Officer

Sylvia Cheung

(Principal Accounting Officer and Principal

Financial Officer)

Michael Levitz

(Principal Accounting Officer and Principal Financial Officer)

March 5, 2021

/s/ JOSEPH L.

/s/ JEFFERY S.

Director, Chairman of the Board

March 5, 2021

/s/ JOSEPH L.

March 5, 2021

/s/ JOHN HENNEMAN

John Henneman

March 5, 2021

/s/ RAYMOND J.

3 unchanged sentences

March 5, 2021

/s/ JEFFERY S.

/s/ STEPHEN RICHARD

Stephen Richard

March 5, 2021

/s/ SUSAN VOGT

March 5, 2021

Compared sentence by sentence after normalising whitespace, quotation marks, case and digits, so re-formatting and restated figures do not read as changed language. Wording changes appear as one removal and one addition. The current filing and the prior one are authoritative.

What changed 10-K

Item 9A. Controls and Procedures