Unresolved Staff Comments
−Removed: Cybersecurity
+Added: Cybers ecurity
We recognize the critical importance of maintaining the trust and confidence of all of our stakeholders.
2 unchanged sentences
The Company’s cybersecurity program is focused on the following key areas :
−Removed: The Board’s oversight of cybersecurity risk management is supported by the Audit Committee of the Board (the “Audit Committee”), which regularly interacts with our Head of IT and our executive management team.
+Added: The Board of Directors’ oversight of cybersecurity risk management is supported by the Audit Committee of the Board of Directors (the “Audit Committee”), which regularly interacts with our Head of IT and our executive management team.
Collaborative Approach:
−Removed: We have implemented a cross-functional approach to identifying, preventing, and mitigating cybersecurity threats and incidents, while also implementing controls and procedures that provide for the prompt
−Removed: escalation of certain cybersecurity incidents so that decisions regarding the public disclosure and reporting of such incidents can be made by management in a timely manner.
+Added: We have implemented a cross-functional approach to identifying, preventing, and mitigating cybersecurity threats and incidents, while also implementing controls and procedures that provide for the prompt escalation of certain cybersecurity incidents so that decisions regarding the public disclosure and reporting of such incidents can be made by management in a timely manner.
Technical Safeguards:
12 unchanged sentences
These activities may be performed by external cybersecurity and application security professionals.
−Removed: The Board , in coordination with the Audit Committee, oversees our risk management process.
−Removed: The Board and the Audit Committee also receive prompt and timely information regarding any cybersecurity incident that meets established reporting thresholds, as well as ongoing updates regarding any such incident until it has been addressed.
+Added: The Board of Directors, in coordination with the Audit Committee, oversees our risk management process.
+Added: The Board of Directors and the Audit Committee also receive prompt and timely information regarding any cybersecurity incident that meets established reporting thresholds, as well as ongoing updates regarding any such incident until it has been addressed.
On a quarterly basis, the Audit Committee discuss our approach to cybersecurity risk management with the Head of IT.
5 unchanged sentences
For more information on our cybersecurity risks , see Item 1A “Risk Factors.”
+Added: Our principal executive office is located at 10770 Wateridge Circle in San Diego, California, and consists of approximately 45,000 square feet of leased office and laboratory space under a lease for a term of 124 months, beginning on April 5, 2021.
+Added: The terms of the Lease Agreement provide us with an option to extend the term of the lease for an additional five years, as well as a one-time option to terminate the lease after seven years with the payment of a termination fee.
+Added: We use these facilities for our administrative, research and development and other activities.
+Added: Legal P roceedings
+Added: On November 20, 2025, we filed a Verified Complaint in Delaware Chancery Court, requesting a court declaration that TESARO, Inc.
+Added: (“Tesaro”) has materially breached the parties’ Collaboration and Exclusive License Agreement (“Collaboration Agreement”) and that GSK, Tesaro’s corporate parent, has tortiously interfered with the Collaboration Agreement.
+Added: We have requested that the court declare that we are entitled to all rights and remedies under the Collaboration Agreement.
+Added: While we had approached Tesaro to engage in good faith discussions to potentially resolve these claims, on November 20, 2025, Tesaro, without notice, initiated a lawsuit against us.
+Added: Tesaro’s complaint includes a request for a declaration that it has not breached the Collaboration Agreement and for an injunction prohibiting AnaptysBio from terminating the Collaboration Agreement.
+Added: Tesaro also alleges that AnaptysBio has materially breached the agreement, entitling Tesaro to exercise certain rights and remedies under the agreement.
+Added: Tesaro’s claim for breach is predicated on an allegation that AnaptysBio improperly alleged that Tesaro had breached the Collaboration Agreement, which allegedly caused an anticipatory breach of contract.
+Added: Through that claim, we believe that Tesaro seeks to improperly punish us for and restrain us from exercising our legal rights under the Collaboration Agreement in violation of Delaware’s anti-SLAPP statute.
+Added: We believe that Tesaro’s claims are entirely without merit and have moved to dismiss the anticipatory breach claim.
+Added: Mine S afety Disclosures
+Added: Not applicable.
Compared sentence by sentence after normalising whitespace, quotation marks, case and digits, so re-formatting and restated figures do not read as changed language. Wording changes appear as one removal and one addition. The current filing and the prior one are authoritative.