6 unchanged sentences
If we do not achieve commercial success with sotagliflozin, our business will suffer and our stock price will likely decline.
−Removed: • We depend heavily on our ability to obtain positive results from our ongoing Phase 2 clinical trials of LX9211 in diabetic neuropathic pain and post-herpetic neuralgia.
−Removed: If we fail to successfully complete and obtain positive results from such clinical trials, our business will suffer and our stock price will likely decline.
+Added: • We depend on our ability to obtain positive results from our ongoing Phase 2 clinical trial of LX9211 in post-herpetic neuralgia.
+Added: If we fail to successfully complete and obtain positive results from such clinical trial, our business will suffer and our stock price will likely decline.
• Clinical testing of our drug candidates in humans is an inherently risky and time-consuming process that may fail to demonstrate safety and efficacy, which could result in the delay, limitation or prevention of regulatory approval.
18 unchanged sentences
Risks Related to Our Relationships with Third Parties
−Removed: • We depend on our ability to establish collaborations with pharmaceutical and biotechnology companies for the development and commercialization of our other drug candidates.
−Removed: If we are unable to establish such collaborations, or if pharmaceutical products are not successfully and timely developed and commercialized under such collaborations, our opportunities to generate revenues from our other drug candidates will be greatly reduced.
+Added: • We depend on our ability to establish collaborations with pharmaceutical and biotechnology companies for the development and commercialization of our drug candidates, particularly for the development and commercialization of LX9211 for neuropathic pain.
+Added: If we are unable to establish such collaborations, or if pharmaceutical products are not successfully and timely developed and commercialized under such collaborations, our opportunities to generate revenues from our drug candidates will be greatly reduced.
• Conflicts with our collaborators could jeopardize the success of our collaborative agreements and harm our product development efforts .
25 unchanged sentences
Risk Factors” included in our annual report on Form 10-K for the year ended December 31, 2021 as filed with the Securities and Exchange Commission.
+Added: 3.1 — Fifth Amended and Restated Certificate of Incorporation (filed as Exhibit 3.1 to the Company’s Current Report on Form 8-K dated May 20, 2022 and incorporated by reference herein).
+Added: — Certification of Principal Executive Officer Pursuant to Section 302 of the Sarbanes-Oxley Act of 2002
+Added: — Certification of Principal Financial Officer Pursuant to Section 302 of the Sarbanes-Oxley Act of 2002
+Added: — Certification of Principal Executive and Principal Financial Officers Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002
+Added: — XBRL Instance Document
+Added: — XBRL Taxonomy Extension Schema Document
+Added: — XBRL Taxonomy Extension Calculation Linkbase Document
+Added: — XBRL Taxonomy Extension Definition Linkbase Document
+Added: — XBRL Taxonomy Extension Label Linkbase Document
+Added: — XBRL Taxonomy Extension Presentation Linkbase Document
+Added: 104 — Cover Page Interactive Data File (embedded within the Inline XBRL document)
+Added: _____________________
+Added: * Filed herewith.
+Added: Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.
+Added: Lexicon Pharmaceuticals, Inc.
+Added: August 3, 2022 By:
+Added: /s/ Lonnel Coats
+Added: Chief Executive Officer
+Added: August 3, 2022 By:
+Added: /s/ Jeffrey L.
+Added: President and Chief Financial Officer
Compared sentence by sentence after normalising whitespace, quotation marks, case and digits, so re-formatting and restated figures do not read as changed language. Wording changes appear as one removal and one addition. The current filing and the prior one are authoritative.