UNITED
STATES
SECURITIES
AND EXCHANGE COMMISSION
Washington,
D.C. 20549
FORM
10-Q
(Mark
One)
☒
QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934
For
the quarterly period ended January 31, 2026
☐
TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934
For
the transition period from to
Commission
File No. 001-40101
BRIACELL
THERAPEUTICS CORP.
(Exact
name of registrant as specified in its charter)
British
Columbia, Canada
47-1099599
(State
or other jurisdiction of
incorporation
or organization)
(I.R.S.
Employer
Identification
No.)
235
15 th Street, Suite 300 ,
West
Vancouver ,
BC ,
V7T 2X1
(Address
of Principal Executive Offices, including zip code)
604 - 921-1810
(Registrant’s
telephone number, including area code)
N/A
(Former
name, former address and former fiscal year, if changed since last report)
Securities
registered pursuant to Section 12(b) of the Act:
Title
of each class
Trading
Symbol
Name
of each exchange on which registered
Common
shares, no par value
BCTX
The
Nasdaq Stock Market LLC
Warrants
to purchase common shares, no par value
BCTXW
The
Nasdaq Stock Market LLC
Warrants
to purchase common shares, no par value
BCTXZ
The
Nasdaq Stock Market LLC
Warrants
to purchase common shares, no par value
BCTXL
The
Nasdaq Stock Market LLC
Indicate
by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange
Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2)
has been subject to such filing requirements for the past 90 days. Yes ☒ No ☐
Indicate
by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule
405 of Regulation S-T (§232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant
was required to submit such files). Yes ☒ No ☐
Indicate
by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting
company, or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,”
“smaller reporting company,” and “emerging growth company” in Rule 12b-2 of the Exchange Act.
☐
Large accelerated filer
☐Accelerated
filer
☒
Non-accelerated filer
☒
Smaller reporting company
☒
Emerging growth company
If
an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying
with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐
Indicate
by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act): Yes ☒ No ☐
As
of March 10, 2026, 7,250,487 common shares, no par value per share, of the Company were issued and outstanding.
BRIACELL
THERAPEUTICS CORP.
Form
10-Q
Table
of Contents
Page
Part I. Financial Information
3
Item
1.
Financial Statements
3
Condensed Consolidated Balance Sheets as of January 31, 2026 (unaudited) and July 31, 2025 (audited)
3
Unaudited Condensed Consolidated Statements of Operations and Comprehensive Loss for the Three and Six Months ended January 31, 2026 and 2025
4
Unaudited Condensed Consolidated Statements of Changes in Shareholders’ Equity (Deficit) for the Three and Six Months ended January 31, 2026 and 2025
5
Unaudited Condensed Consolidated Statement of Cash Flows for the Three and Six Months ended January 31, 2026 and 2025
7
Notes to Unaudited Condensed Consolidated Financial Statements
8
Item
2.
Management’s Discussion and Analysis of Financial Condition and Results of Operations
18
Item
3.
Quantitative and Qualitative Disclosures Regarding Market Risk
28
Item
4.
Controls and Procedures
29
Part II. Other Information
30
Item
1.
Legal Proceedings
30
Item
1A.
Risk Factors
30
Item
2.
Unregistered Sales of Equity Securities and Use of Proceeds
30
Item
3.
Defaults Upon Senior Securities
30
Item
4.
Mine Safety Disclosures
30
Item
5.
Other Information
30
Item
6.
Exhibits
30
Part III. Signatures
31
2
PART
I-FINANCIAL INFORMATION
Item
1. Financial Statements
BRIACELL
THERAPEUTICS CORP.
CONDENSED
CONSOLIDATED BALANCE SHEETS
January
31, 2026
July
31, 2025
(Unaudited)
(Audited)
ASSETS
CURRENT ASSETS:
Cash and cash
equivalents
$ 29,903,628
$ 10,493,808
Short-term investments
-
7,372,473
Amounts receivable and
prepaid expenses
2,275,256
2,060,295
Total
current assets
32,178,884
19,926,576
NON-CURRENT ASSETS:
Equity investment in BC
Therapeutics
582,455
524,278
Intangible assets, net
176,889
184,525
Property and equipment,
net
251,141
296,819
Long
term prepaid expenses
405,085
717,508
Total
non-current assets
1,415,570
1,723,130
Total
assets
$ 33,594,454
$ 21,649,706
LIABILITIES AND SHAREHOLDERS’
EQUITY
CURRENT LIABILITIES:
Trade payables
$ 1,879,647
$ 3,283,703
Accrued
expenses and other payables
1,305,903
694,285
Total
current liabilities
3,185,550
3,977,988
NON-CURRENT LIABILITIES:
Warrant
liability
195,096
337,672
Total
non-current liabilities
$ 195,096
$ 337,672
CONTINGENT LIABILITIES AND
COMMITMENTS
-
-
SHAREHOLDERS’ EQUITY:
Share Capital of no par value – Authorized:
unlimited at January 31, 2026 and July 31, 2025; Issued and outstanding: 7,250,487 shares at January 31, 2026 and 1,883,906 July
31, 2025, respectively
117,117,225
101,739,923
Share-based payment reserved
10,896,682
10,316,140
Warrant reserve
30,216,165
17,719,026
Accumulated other comprehensive loss
( 138,684 )
( 138,684 )
Non-controlling interest
( 702,631 )
( 546,795 )
Accumulated deficit
( 127,174,949 )
( 111,755,564 )
Total
shareholders’ equity
30,213,808
17,334,046
Total
liabilities and shareholders’ equity
$ 33,594,454
$ 21,649,706
The
accompanying notes are an integral part of these unaudited condensed consolidated financial statements.
3
BRIACELL
THERAPEUTICS CORP.
CONDENSED
CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS
(Unaudited)
2026
2025
2026
2025
Three
months ended
January 31,
Six
months ended
January 31,
2026
2025
2026
2025
(Unaudited)
(Unaudited)
(Unaudited)
(Unaudited)
Operating Expenses:
Research, development,
and clinical trial expenses, net (note 9)
$ 6,053,689
$ 5,684,777
$ 12,737,332
$ 9,350,118
General
and administrative expenses
1,477,577
1,484,666
3,116,877
2,972,157
Total operating expenses
7,531,266
7,169,443
15,854,209
12,322,275
Operating loss
( 7,531,266 )
( 7,169,443 )
( 15,854,209 )
( 12,322,275 )
Financial expenses, net
84,589
67,358
243,235
79,072
Change in fair value of
the warrant liability
211,777
806,841
142,576
190,198
Share
of loss on equity investment
( 61,993 )
( 42,584 )
( 106,823 )
( 114,099 )
Net loss for the period
$ ( 7,296,893 )
$ ( 6,337,828 )
$ ( 15,575,221 )
( 12,167,104 )
Net
loss attributable to non-controlling interest
( 75,073 )
( 46,408 )
( 155,836 )
( 73,509 )
Net
loss and Comprehensive loss for the period attributable to BriaCell
( 7,221,820 )
( 6,291,420 )
( 15,419,385 )
( 12,093,595 )
Net
loss per share attributable to BriaCell – basic and diluted
$ ( 2.58 )
$ ( 23.31 )
$ ( 6.58 )
$ ( 54.35 )
Weighted average number
of shares used in computing net basic earnings per share of common stock
2,802,337
269,957
2,343,122
222,498
Weighted average number
of shares used in computing net diluted earnings per share of common stock
2,802,337
269,957
2,343,122
222,498
The
accompanying notes are an integral part of these unaudited condensed consolidated financial statements.
4
BRIACELL
THERAPEUTICS CORP.
CONDENSED
CONSOLIDATED STATEMENTS OF CHANGES IN SHAREHOLDERS’ EQUITY
(Unaudited)
FOR
THE THREE AND SIX MONTHS ENDED JANUARY 31, 2026
Number
Amount
capital
reserve
loss
deficit
Interest
(deficit)
Share
capital
Additional
paid in
Warrant
Accumulated
other
comprehensive
Accumulated
Non-
Controlling
Total
shareholders’
Number
Amount
capital
reserve
loss
deficit
Interest
equity
Balance, October 31, 2025
1,883,906
$ 101,739,923
$ 10,610,826
$ 17,719,026
$ ( 138,684 )
$ ( 119,953,129 )
$ ( 627,558 )
$ 9,350,404
Issuance of Options, RSU and PSU
-
-
285,856
-
-
-
-
285,856
Exercise of warrants
1,039,051
-
-
-
-
-
-
-
Issuance of units, net
4,327,530
15,377,302
-
12,497,139
-
-
-
27,874,441
Net loss for the period
-
-
-
-
-
( 7,221,820 )
( 75,073 )
( 7,296,893 )
Balance, January 31,
2026
7,250,487
$ 117,117,225
$ 10,896,682
$ 30,216,165
$ ( 138,684 )
$ ( 127,174,949 )
$ ( 702,631 )
$ 30,213,808
Share
capital
Additional
paid in
Warrant
Accumulated
other
comprehensive
Accumulated
Non-
Controlling
Total
shareholders’
Number
Amount
capital
reserve
loss
deficit
Interest
equity
Balance, July 31, 2025
1,883,906
$ 101,739,923
$ 10,316,140
$ 17,719,026
$ ( 138,684 )
$ ( 111,755,564 )
$ ( 546,795 )
$ 17,334,046
Issuance of Options, RSU and PSU
-
-
580,542
-
-
-
-
580,542
Exercise of prefunded warrants
1,039,051
-
-
-
-
-
-
-
Issuance of units, net
4,327,530
15,377,302
-
12,497,139
-
-
-
27,874,441
Net loss for the period
-
-
-
-
-
( 15,419,385 )
( 155,836 )
( 15,575,221 )
Balance, January 31,
2026
7,250,487
$ 117,117,225
$ 10,896,682
$ 30,216,165
$ ( 138,684 )
$ ( 127,174,949 )
$ ( 702,631 )
$ 30,213,808
5
Share
capital
Additional
paid in
Warrant
Accumulated
other
comprehensive
Accumulated
Non-
Controlling
Total
shareholders’
Number
Amount
capital
reserve
loss
deficit
Interest
equity
Balance, October 31, 2024
241,229
$ 82,040,741
$ 9,456,232
$ 3,930,221
$ ( 138,684 )
$ ( 91,245,872 )
$ ( 329,623 )
$ 3,713,015
Issuance of Options
-
-
635,093
-
-
-
-
635,093
Exercise of prefunded warrants
4,137
796,690
-
( 268,925 )
-
-
-
527,765
Issuance of units
49,333
2,613,688
-
2,075,158
-
-
-
4,688,846
Net loss for the period
-
-
-
-
-
( 6,291,420 )
( 46,408 )
( 6,337,828 )
Balance, January 31,
2025
294,699
$ 85,451,119
$ 10,091,325
$ 5,736,454
$ ( 138,684 )
$ ( 97,537,292 )
$ ( 376,031 )
$ 3,226,891
Share
capital
Additional
paid in
Warrant
Accumulated
other
comprehensive
Accumulated
Non-
Controlling
Total
shareholders’
Number
Amount
capital
reserve
loss
deficit
Interest
equity
Balance, July 31, 2024
121,907
$ 72,166,414
$ 9,189,261
$ 1,844,296
$ ( 138,684 )
$ ( 85,443,697 )
$ ( 302,522 )
$ ( 2,684,932 )
Balance
121,907
$ 72,166,414
$ 9,189,261
$ 1,844,296
$ ( 138,684 )
$ ( 85,443,697 )
$ ( 302,522 )
$ ( 2,684,932 )
Issuance of Options
-
-
902,064
-
-
-
-
902,064
Exercise of prefunded warrants
666
-
-
-
-
-
-
-
Exercise of broker warrants
6,437
1,239,367
-
( 418,352 )
821,015
Issuance of units
165,689
12,045,338
-
4,310,510
-
-
-
16,355,848
Net loss for the period
-
-
-
-
-
( 12,093,595 )
( 73,509 )
( 12,167,104 )
Balance, January 31,
2025
294,699
$ 85,451,119
$ 10,091,325
$ 5,736,454
$ ( 138,684 )
$ ( 97,537,292 )
$ ( 376,031 )
$ 3,226,891
Balance
294,699
$ 85,451,119
$ 10,091,325
$ 5,736,454
$ ( 138,684 )
$ ( 97,537,292 )
$ ( 376,031 )
$ 3,226,891
The
accompanying notes are an integral part of these unaudited condensed consolidated financial statements.
6
BRIACELL
THERAPEUTICS CORP.
CONDENSED
CONSOLIDATED STATEMENT OF CASH FLOWS
(Unaudited)
2026
2025
Six
months ended January 31,
2026
2025
Cash flow from operating
activities
Net loss for the period
$ ( 15,575,221 )
$ ( 12,167,104 )
Adjustments to reconcile net loss to net cash
used in operating activities:
Amortization
7,636
7,636
Depreciation
45,678
45,678
Share-based compensation
580,542
552,064
Share of loss on equity investment
106,823
114,099
Change in fair value of
warrants
( 142,576 )
( 190,198 )
Changes in working capital:
Decrease in amounts receivable
and prepaid expenses
97,462
642,846
Decrease in accounts payable
( 1,404,056 )
( 2,167,542 )
Increase
in accrued expenses and other payables
611,618
287,223
Total cash flow from operating
activities
( 15,672,094 )
( 12,875,298 )
Cash flows from Investing
activities
Proceeds from short term
investments
7,372,473
-
Equity
investment in BC Therapeutics
( 165,000 )
( 150,000 )
Total
cash flow from investing activities
7,207,473
( 150,000 )
Cash flows from financing
activities
Proceeds from exercise of warrants
-
821,015
Proceeds
from the issuance of shares, net of issuance costs
27,874,441
16,355,848
Total
cash flow from financing activities
27,874,441
17,176,863
Increase in cash
and cash equivalents
19,409,820
4,151,565
Cash and cash equivalents
at beginning of the period
10,493,808
862,089
Cash and cash equivalents
at end of the period
$ 29,903,628
$ 5,013,654
The
accompanying notes are an integral part of these unaudited condensed consolidated financial statements.
7
BriaCell
Therapeutics Corp
Notes
to the Condensed Consolidated Financial Statements
(Unaudited,
expressed in US Dollars, except share and per share data and unless otherwise indicated)
NOTE
1: GENERAL AND GOING CONCERN
a.
BriaCell
Therapeutics Corp. (“BriaCell” or the “Company”) was incorporated under the Business Corporations Act (British
Columbia) on July 26, 2006 and is listed on the Toronto Stock Exchange (“TSX”) under the symbol “BCT”. The
Company also trades on the Nasdaq Capital Market (“NASDAQ”) under the symbols “BCTX”, “BCTXW” “BCTXZ”, and “BCTXL”.
b.
BriaCell
is a clinical-stage biotechnology company that is developing novel immunotherapies to transform cancer care. The Company is currently
advancing its Bria-IMT™ targeted immunotherapy in combination with an immune check point inhibitor (Retifanlimab) in a pivotal 1
Phase 3 study in metastatic breast cancer. Bria-IMT™ is currently under Fast Track Designation by the U.S. Food and Drug Administration
(the “FDA”) intended to accelerate the review process of novel treatments that address unmet medical needs. Positive completion
of the pivotal study, following review by FDA, could lead to full approval of the Bria-IMT™ immune checkpoint inhibitor combination
in metastatic breast cancer. BriaCell Phase 1/2 Study of Bria-OTS™, BriaCell’s personalized off-the-shelf immunotherapy, also
known as Bria-BRES™, in metastatic breast cancer is ongoing BriaCell is currently developing Bria-OTS™ and its advanced form,
Bria-OTS+™, as a platform technology for personalized off-the-shelf immunotherapies for numerous types of cancer. The Company announced
BriaCell had received positive feedback from its Pre-Investigational New Drug Application (Pre-IND) meeting with FDA for Bria-PROS+™
for prostate cancer.
c.
Basis
of presentation of the financial statements:
The
accompanying unaudited condensed consolidated financial statements have been prepared in accordance with accounting principles generally
accepted in the United States of America (“U.S. GAAP”) for interim financial information and in accordance with the instructions
to Form 10-Q and Article 8 of Regulation S-X promulgated by the U.S Securities and Exchange Commission (the “SEC”). Certain
information or footnote disclosures normally included in financial statements prepared in accordance with U.S. GAAP have been condensed
or omitted pursuant to the rules and regulations of the SEC for interim financial reporting. Accordingly, they do not include all
the information and footnotes necessary for a complete presentation of financial position, results of operations, or cash flows.
In the opinion of management, the accompanying unaudited condensed consolidated financial statements include all adjustments consisting
of a normal recurring nature which are necessary for a fair presentation of the financial position, operating results, and cash flows
for the periods presented.
The
accompanying unaudited condensed consolidated financial statements should be read in conjunction with the Company’s Annual
Report for the year ended July 31, 2025, filed with the SEC on October 16, 2025. The interim period results do not necessarily indicate
the results that may be expected for any other interim period or for the full fiscal year.
d.
Going
concern
The
Company continues to devote substantially all of its efforts toward research and development activities. In the course of such activities,
the Company has sustained operating losses and expects such losses to continue in the foreseeable future. The Company’s accumulated
deficit as of January 31, 2026 was $ 127,174,949 and negative cash flows from operating activities during the six-month period ended
January 31, 2026 was $ 15,672,094 . The Company is planning to finance its operations by exploring additional sources of capital and
financing, while managing its existing working capital resources. During the year ended July 31, 2025, the Company raised $ 50.9 million
in gross proceeds from equity financings and, in January 2026, completed a public offering generating approximately $ 30.0 million in
gross proceeds. However, the Company’s ability to continue as a going concern is dependent upon its
ability to attain future profitable operations and to continue to obtain the necessary financing to meet its obligations arising
from normal business operations when they come due. The uncertainty of the Company’s ability to raise such financial capital
casts substantial doubt on the Company’s ability to continue as a going concern. These condensed consolidated financial statements
do not include any adjustments to the amounts and classification of assets and liabilities that might be necessary should the Company
not be able to continue as a going concern.
e.
The
Company has two wholly-owned U.S. subsidiaries: (i) BriaCell Therapeutics Corp. (“BTC”), which was incorporated in April
3, 2014, under the laws of the state of Delaware, and (ii) BTC has a wholly-owned subsidiary, Sapientia Pharmaceuticals, Inc. (“Sapientia”),
which was incorporated in September 20, 2012, under the laws of the state of Delaware. The Company also has one Canadian subsidiary:
BriaPro Therapeutics Corp, (“BriaPro”) which was incorporated on May 15, 2023, under the Business Corporations Act (British
Columbia). BriaPro was established to complete a plan of arrangement spinout transaction in August 2023, pursuant to which certain
pipeline assets of the Company were spun-out to BriaPro, including Bria-TILsRx™ and protein kinase C delta (PKCδ) inhibitors
for multiple indications including cancer (the “BriaPro Assets”), resulting in a two-third (2/3) owned subsidiary of
the Company with the remaining one-third (1/3) held by the Company’s shareholders (the “Amalgamation” and the “Amalgamation
Agreement”) – see also note 7(a). (Sapientia and BTC and BriaPro together, the “Subsidiaries”).
8
BriaCell
Therapeutics Corp
Notes
to the Condensed Consolidated Financial Statements
(Unaudited,
expressed in US Dollars, except share and per share data and unless otherwise indicated)
NOTE
2: SIGNIFICANT ACCOUNTING POLICIES
a.
Use of estimates :
The
preparation of financial statements in conformity with U.S. GAAP requires management to make
estimates, judgments and assumptions that affect the amounts reported in the condensed consolidated
financial statements and accompanying notes. The Company’s management believes that
the estimates, judgment and assumptions used are reasonable based upon information available
at the time they are made. These estimates, judgments and assumptions can affect the reported
amounts of assets and liabilities at the dates of the condensed consolidated financial statements,
and the reported amount of expenses during the reporting periods. Actual results could differ
from those estimates.
Significant
estimates include the determination of the fair value of warrant liabilities, which are measured using valuation models that require
assumptions such as share price volatility, expected term, and risk-free interest rates. Changes in these inputs could materially
impact the valuation of the warrant liability and the amounts recognized in the condensed consolidated financial statements.
b.
Prepaid expenses
The
Company has prepaid certain expenses in respect of its pivotal phase III trial and estimates the period over which such expenses
will be incurred. As of January 31, 2026, the Company revised its estimate of the time to completion in respect of this trial. Amounts
estimated to be expenses in more than 12 months have been classified to long-term prepaid expenses.
c.
The useful life of property and equipment
Property
and equipment are depreciated over their useful lives. Useful lives are based on management’s estimates of the period that
the assets will be used which are periodically reviewed for continued appropriateness. Changes to estimates can result in significant
variations in the amounts charged to the consolidated statement of operations and comprehensive loss in specific periods.
d.
Investment equity method :
Investments
in entities over which the Company does not have a controlling financial interest but has significant influence are accounted for
using the equity method, with the Company’s share of losses reported in the loss from equity method investments on the statements
of operation and comprehensive loss. The Company has a 67.8 % interest in BC Therapeutics. Management evaluates whether it has control
over the investee in accordance with the guidance of ASC 810, which requires judgment to assess factors such as power over significant
activities of the investee, exposure to variable returns, and the ability to affect those returns. Based on this evaluation, management
determines whether control or significant influence is present for accounting purposes.
e.
Segment reporting :
The
Company manages its business activities on a consolidated basis and operates as one reportable segment. The Company’s operations
are focused on the research and development of its immunotherapy product candidates and related supporting activities. The Chief
Executive Officer is identified as the Company’s Chief Operating Decision Maker (“CODM”).
The
accounting policies of the segment are the same as those used in the condensed consolidated financial statements. The CODM evaluates
the Company’s performance and allocates resources using consolidated financial information, including net loss and cash flow
forecasts. The Company’s significant expenses, which consist primarily of research and development and general and administrative
expenses, are consistent with the captions presented on the consolidated statements of operations and comprehensive loss.
f.
Share-based compensation :
The
Company accounts for share-based compensation in accordance with ASC No. 718, “Compensation – Stock Compensation”,
which requires companies to estimate the fair value of equity-based payment awards on the date of grant using an option-pricing model.
The value of the award is recognized as an expense over the requisite service periods, which is the vesting period of the respective
award, on a straight-line basis when the only condition to vesting is continued service.
The
Company has selected the Black-Scholes option-pricing model as the most appropriate fair value method for its option awards. The
Company recognizes forfeitures of equity-based awards as they occur. Restricted share units use the share price on the grant date
to determine the fair value of the restricted share unit award.
For
performance-based stock units (“PSUs”) that do not contain market conditions, the Company measures the grant-date fair
value using the closing price of the common stock on the date of grant. Compensation cost for these awards is recognized over the
requisite service period based on the number of awards that are expected to vest. Management evaluates the probability of achieving
the applicable performance conditions each reporting period and adjusts the expense recognition accordingly.
As
of the date of this report, the Company has issued stock options, RSUs, and PSUs that do not contain market conditions.
g.
Recently issued and adopted accounting standards :
As
an “emerging growth company,” the Jumpstart Our Business Startups Act (“JOBS Act”) allows the Company to
delay adoption of new or revised accounting pronouncements applicable to public companies until such pronouncements are made applicable
to private companies. The Company has elected to use this extended transition period under the JOBS Act. The adoption dates discussed
below reflect this election. The pronouncements below relate to standards that impact the Company.
9
BriaCell
Therapeutics Corp
Notes
to the Condensed Consolidated Financial Statements
(Unaudited,
expressed in US Dollars, except share and per share data and unless otherwise indicated)
NOTE
2: SIGNIFICANT ACCOUNTING POLICIES (Cont.)
1.
In
January 2025, the FASB issued ASU 2025-01 - Income Statement — Reporting Comprehensive Income — Expense Disaggregation
Disclosures (Subtopic 220-40): Clarifying the Effective Date. This standard amends the guidance issued in 2024 to confirm that
all public business entities must present the required expense-disaggregation disclosures in annual periods beginning after December
15, 2026, and interim periods within annual periods beginning after December 15, 2027. The ASU is effective for years beginning after
those dates, but early adoption is permitted. This ASU should be applied on a prospective basis, although retrospective application
is permitted. Because the amendment only affects disclosure timing, the Company does not expect this standard to have a material
impact on its financial statements and disclosures.
2.
In
June 2025, the FASB issued ASU 2025-03 - Business Combinations (Topic 805) and Consolidation (Topic 810): Determining the Accounting
Acquirer in a Variable-Interest Entity . This standard clarifies that when a business combination is effected primarily by exchanging
equity interests and the legal acquiree is a variable-interest entity (“VIE”) that meets the definition of a business,
entities must identify the accounting acquirer using the factors in ASC 805-10-55-12 through 55-15, rather than relying solely on
the VIE consolidation model. The ASU is effective for years beginning after December 15, 2026, but early adoption is permitted. This
ASU should be applied on a prospective basis, although retrospective application is permitted. The Company is currently evaluating
the impact of this standard on its financial statements and disclosures.
NOTE
3: INVESTMENT IN BC THERAPEUTICS INC.
On
December 21, 2021, the Company and BC Therapeutics, Inc. (“BC Therapeutics” or “the Investee”) entered a
share purchase agreement (“SPA”), pursuant to which the Company initially provided a loan of $ 300,000 to BC Therapeutics,
with no interest to be paid. Subsequently, in accordance with the SPA, this loan was converted into an equity investment in BC Therapeutics
at a rate of $ 1.25 per share, resulting in a 37.5 % ownership interest (“Initial Investment”).
Pursuant
to the SPA (“Initial Investment”), Briacell also received two options to invest an additional $ 225,000 per option at
$ 1.25 per BC Therapeutics share. The first option expired on February 15, 2024 (“First BC Therapeutics Option”) and the
second option expired on June 30, 2024 (“Second BC Therapeutics Options”, together, the “BC Therapeutic Options”).
In accordance with ASC 321 and ASC 815, the BC Therapeutics Options were valued at $ 76,350 in accordance with the Black Scholes Option
Price Model, using the following assumptions: Share price: $ 1.25 , Exercise price: $ 1.25 , Dividend yield: 0 %, Risk free interest rate:
4.902 %, Volatility: 100 %.
BC
Therapeutics has a board of four representatives, with two representatives appointed by BriaCell and two representatives appointed
by the existing shareholders. All significant decisions related to BC Therapeutics require the approval of at least a majority of
the board members.
The
Company initially acquired a significant interest in BC Therapeutics on February 1, 2024,
by exercising the First BC Therapeutics Option, increasing its ownership to 51.2 %. On August
7, 2024, following the expiration of the original Second BC Therapeutics Option, the Company
and BC Therapeutics amended the SPA to introduce new options, allowing the exercise in tranches
of at least 20,000 shares at $ 1.25 per share. On March 18, 2025, the SPA was amended a second
time, such that the Second BC Therapeutics Option is increased to 424,000 shares and expires
in June 2026 (a one year extension). During the six-month period ended January 31, 2026,
the Company exercised this option in totaling $ 165,000 and received 132,000 shares.
As
of January 31, 2026, the Company holds 816,000 of the 1,204,000 issued and outstanding shares in BC Therapeutics, representing a
67.8 % ownership interest. In addition, 28,000 shares remain available for purchase under the Second BC Therapeutics Option at an
exercise price of $ 1.25 per share; these options expire on June 30, 2026.
In
accordance with ASC 810, the Company continues to account for the investment under the equity
method of accounting as the Company does not exercise control over BC Therapeutics.
10
BriaCell
Therapeutics Corp
Notes
to the Condensed Consolidated Financial Statements
(Unaudited,
expressed in US Dollars, except share and per share data and unless otherwise indicated)
NOTE
3: INVESTMENT IN BC THERAPEUTICS INC. (Cont.)
Changes
in the Company’s equity investment in BC Therapeutics is summarized as follows:
SCHEDULE OF CHANGES IN INVESTMENT
Balance –
August 1, 2024
$ 418,490
Funding
(including the value of the BC Therapeutics Options)
330,000
Share
of losses
( 224,212 )
Balance – July 31,
2025
524,278
Funding
(including the value of the BC Therapeutics Options)
165,000
Share
of losses
( 106,823 )
Balance
– January 31, 2026
$ 582,455
The
following amounts represent the Company’s 67.8% share of the assets of BC Therapeutics (July 31, 2025 – 63.1%):
SCHEDULE OF ASSETS AND LIABILITIES OF BC THERAPEUTICS
As
of
January
31, 2026
Current
assets: Cash
$ 1,400
Net assets
$ 1,400
NOTE
4: CONTINGENT LIABILITIES AND COMMITMENTS
a.
BriaPro
Warrants
Upon
the exercise of certain BriaCell warrants that were outstanding at the time of the Amalgamation
Agreement with BriaPro (“Briacell Legacy Warrants”), BriaCell shall, as agent
for BriaPro, collect and pay to BriaPro an amount based on an agreed formula. As of January 31, 2026, this amount totaled of up to $ 241,164 and is eliminated on consolidation.
Pursuant
to the Amalgamation Agreement, each BriaCell warrant in issuance at the time of the Amalgamation (“Briacell Legacy Warrant”)
shall, in accordance with its terms, entitle the holder thereof to receive, upon the exercise thereof, one BriaCell Share (and post
Reverse Splits, as defined below– 150 Briacell Shares) and one BriaPro Share for the original exercise price. Warrants issued
by the Company, subsequent to the Arrangement are not subject to the terms above.
Upon
the exercise of 150 BriaCell Legacy Warrants (post Reverse Splits), BriaCell shall, as agent for BriaPro, collect and pay to BriaPro
an amount for each one (1) BriaPro Share so issued that is equal to the exercise price under the 150 BriaCell Legacy Warrants multiplied
by the fair market value of one (1) BriaPro Share at the Effective Date divided by the total fair market value of one (1) BriaCell
Share and one (1) BriaPro Share at the Effective Date (“BriaPro Warrant Shares”). On a Reverse Split basis, as of January
31, 2026, 54,075 Briacell Legacy Warrants are exercisable into 54,075 Briacell Shares and 8,111,714 BriaPro Shares.
b.
Lease
The
Company has a month-to-month commitment for office and lab space in Philadelphia, PA, costing approximately $ 43,500 per month.
NOTE
5: FAIR VALUE MEASUREMENTS
The
following table presents information about our financial instruments that are measured at fair value on a recurring basis as of January
31, 2026 and July 31, 2025:
SCHEDULE OF FINANCIAL INSTRUMENTS MEASURED AT FAIR VALUE ON A RECURRING BASIS
Fair
Value Measurements at
January
31, 2026
July
31, 2025
Level
1
Level
2
Total
Level
1
Level
2
Total
Financial
Assets:
Cash
and cash equivalents
29,903,628
-
29,903,628
10,493,808
-
10,493,808
Short-term investments
-
-
-
7,372,473
-
7,372,473
Total
assets measured at fair value
$ 29,903,628
$ -
$ 29,903,628
$ 17,866,281
$ -
$ 17,866,281
Financial
liabilities:
Warrants
liability
38,578
156,518
195,096
151,586
186,086
337,672
Total
liabilities measured at fair value
$ 38,578
$ 156,518
$ 195,096
$ 151,586
$ 186,086
$ 337,672
11
BriaCell
Therapeutics Corp
Notes
to the Condensed Consolidated Financial Statements
(Unaudited,
expressed in US Dollars, except share and per share data and unless otherwise indicated)
NOTE
5: FAIR VALUE MEASUREMENTS (Cont.)
We
classify our cash and cash equivalents and the liability in respect of publicly traded warrants within Level 1 because we use quoted
market prices in active markets.
As
of January 31, 2026, the Company did not hold any short-term investments. As of July 31, 2025, the Company held Level 1 short-term investments
measured using quoted prices in active markets, with coupon rates ranging from 3 % to 5.51 %.
The
fair value of the warrant liability for non-public warrants is measured using inputs other than quoted prices included in Level 1 that
are observable for the liability either directly or indirectly, and thus are classified as Level 2 financial instruments.
NOTE
6: SHAREHOLDERS’ EQUITY
a.
Authorized share capital
The
authorized share capital consists of an unlimited number of common shares with no par value.
b.
Issued share capital
(i)
Reverse
Stock Split:
On
January 3, 2025, the Company’s board of directors approved a reverse stock split of the Company’s common shares on a
1-for-15 basis, which became effective on January 24, 2025 and on August 25, 2025 (the “Effective Date”), the Company
effected a reverse stock split of its common shares on a 1-for-10 basis (the “Reverse Splits”).
As
a result of the Reverse Splits, every one hundred and fifty (150) pre-split common shares issued and outstanding were automatically
combined into one (1) new common share. No fractional common shares were issued in connection with the Reverse Splits. Instead, any
fractional common shares resulting from the January 2025 Reverse Split were deemed to have been tendered to the Company for cancellation
for no consideration.
Following
the January 2025 Reverse Split, the number of common shares outstanding were 294,694 . After giving effect to subsequent share issuances
and the August 2025 Reverse Split, the number of common shares outstanding was 1,883,906 .
The
Reverse Splits also resulted in a proportional adjustment to the number of common shares issuable upon the exercise of the Company’s
outstanding warrants, stock options, and other convertible securities, as well as an adjustment to the exercise prices and conversion
prices, as applicable.
All
share and per share amounts in the accompanying condensed consolidated financial statements and related notes have been retroactively
adjusted to reflect both the January 2025 Reverse Split and the August 2025 Reverse Split for all periods presented.
(ii)
The
Company issued the following shares during the six-month period ended January 31, 2026:
1.
On January 15, 2026, the Company closed a public offering for the purchase and sale of 5,366,726 units of the Company for aggregate
gross proceeds of approximately $ 30.0 million before deducting placement agent fees and other offering expenses (the “January
2026 Offering”). Each unit consisted of one common share (or one pre-funded warrant (“Pre-Funded Warrants”) in
lieu thereof) and one warrant to purchase one common share of the Company at a combined purchase price of $ 5.59 per unit. The warrants
have an exercise price of $ 6.93 per share, are immediately exercisable, and expire five years from the date of issuance (“January
2026 Warrants”). The common shares (or Pre-Funded Warrants) and January 2026 Warrants were purchased together in the offering
but were issued separately. Total issuance costs associated with the offering were approximately $ 2,125,100 ,
excluding the fair value of placement agent warrants.
In
connection with the January 2026 Offering, the Company issued 161,001 placement agent warrants. The placement agent warrants are
immediately exercisable at an exercise price of $ 8.39 per share and expire five years from the date of issuance.
The
fair value of the 5,366,726 January 2026 Warrants was determined to be $ 13,103,125 (gross, before deducting share issuance costs)
using the Black-Scholes option pricing model, with the following assumptions: share price – $ 3.15 ; exercise price – $ 6.93 ;
expected life – 5 years; annualized volatility – 123 %; dividend yield – 0 %; risk-free rate – 3.762 %.
The
fair value of the 161,001 placement agent warrants was determined to be $ 572,334 using the Black-Scholes option pricing model, with
the following assumptions: share price – $ 4.49 ; exercise price – $ 8.39 ; expected life – 5 years; annualized volatility
– 123 %; dividend yield – 0 %; risk-free rate – 3.762 %.
The
amounts were credited to the warrant reserve at the date of the January 2026 Offering.
12
BriaCell
Therapeutics Corp
Notes
to the Condensed Consolidated Financial Statements
(Unaudited,
expressed in US Dollars, except share and per share data and unless otherwise indicated)
NOTE
6: SHAREHOLDERS’ EQUITY (Cont.)
c.
Share Purchase Warrants
A
summary of changes in share purchase warrants for the six-month period ending January 31, 2026 is presented below:
SUMMARY OF CHANGES IN WARRANTS
Number of
options
outstanding
Weighted
average
exercise
price
Balance,
July 31, 2025
1,653,914
$ 58.27
Expired
( 346 )
( 579.97 )
Granted
in the January 2026 Offering
5,366,726
6.93
Balance,
January 31, 2026
7,020,294
19.00
(ii)
As
of January 31, 2026, warrants outstanding were as follows:
SCHEDULE OF WARRANTS OUTSTANDING
Number
of
Warrants
Exercise
Price
Exercisable
At
January
31, 2026
Expiry
Date
(*) 25,978
$ 796.88
25,978
February 26,
2026 – April 26, 2026
(*) 27,820
$ 928.50
27,820
December 7, 2026
16,019
$ 316.50
16,019
November 17, 2029
27,753
$ 127.50
27,753
October 2, 2029
49,333
$ 140.63
49,333
December 12, 2029
306,665
$ 52.50
306,665
April 28, 2030
1,200,000
$ 15.00
1,200,000
July 15, 2030
5,366,726
$ 6.93
5,366,726
January
15, 2031
7,020,294
7,020,294
(*)
Briacell
Legacy Warrants – see note 1(e) and note 4(a)
d.
Compensation Warrants
(i)
A
summary of changes in compensation warrants for the six-month period ended January 31, 2026 is presented below:
SUMMARY OF CHANGES IN WARRANTS
Number
of warrants
outstanding
Weighted
average
exercise
price
Balance,
July 31, 2025
28,072
93.54
Expired
( 34 )
( 579.97 )
Granted
in the January 2026 Offering
161,001
8.39
Balance,
January 31, 2026
189,039
$ 20.93
(ii)
As
of January 31, 2026, compensation warrants outstanding were as follows:
SCHEDULE OF WARRANTS OUTSTANDING
Number
of
Warrants
Exercise
Price
Exercisable
At
January
31, 2026
Expiry
Date
(*) 113
$ 796.88
113
February 26,
2026
(*) 164
$ 928.50
164
June 7, 2026
333
$ 348.00
333
May 17, 2029
4,108
$ 129.38
4,108
September 12, 2029
1,709
$ 182.81
1,709
October 2, 2029
2,466
$ 140.63
2,466
December 12, 2029
3,812
$ 50.00
3,812
February 5, 2030
15,333
$ 56.50
15,333
April 28, 2030
161,001
$ 8.39
161,001
January
15, 2031
189,039
189,039
(*)
Briacell
Legacy Warrants – see note 1(e) and note 4(a)
13
BriaCell
Therapeutics Corp
Notes
to the Condensed Consolidated Financial Statements
(Unaudited,
expressed in US Dollars, except share and per share data and unless otherwise indicated)
NOTE
6: SHAREHOLDERS’ EQUITY (Cont.)
e.
Warrant liability continuity
The
following table presents the summary of the changes in the fair value of the warrants:
SCHEDULE OF CHANGE IN FAIR VALUE OF WARRANTS
Warrants
liability
Balance as
of August 1, 2025
$ 337,672
Change
in fair value during the period
( 142,576 )
Balance
as of January 31, 2026
$ 195,096
The
key inputs used in the valuation of the non-public warrants as of January 31, 2026 and at July 31, 2025 were as follows:
SCHEDULE OF VALUATION OF NON PUBLIC OFFERING BROKER WARRANTS
January
31, 2026
July
31, 2025
Share price
$ 4.30
$ 7.50
Exercise price
$ 796.88 - 928.50
$ 796.88 - 928.50
Expected life (years)
0.07 - 0.85
0.57 - 1.35
Volatility
177 - 355 %
157 - 209 %
Dividend yield
0 %
0 %
Risk free rate
3.48 - 3.64 %
4.10 %
The
key inputs used in the valuation of the of the BriaPro Warrant Shares as of January 31, 2026 were as follows:
SCHEDULE OF BRIA PRO WARRANTS
August
31, 2023
(Effective
Date)
January
31, 2026
Share price
$ 0.0365
$ 0.0365
Exercise price
$ 0.0206 - 0.0308
$ 0.0206 - 0.0308
Expected life (years)
2.21 - 3.27
$ 0.07 - 0.85
Volatility
100 %
177 - 355 %
Dividend yield
0 %
0 %
Risk free rate
4.40 %
2.14 - 2.33 %
14
BriaCell
Therapeutics Corp
Notes
to the Condensed Consolidated Financial Statements
(Unaudited,
expressed in US Dollars, except share and per share data and unless otherwise indicated)
NOTE
7: SHARE-BASED COMPENSATION
a.
On
August 2, 2022, the Company approved an omnibus equity incentive plan (“Omnibus Plan),
which will permit the Company to grant incentive stock options, preferred share units, restricted
share units (“RSU’s”), performance-based share units (“PSUs”),
and deferred share units (collectively, the “Awards”) for the benefit of any
employee, officer, director, or consultant of the Company or any subsidiary of the Company.
The maximum number of shares available for issuance under the Omnibus Plan shall not exceed
15 % of the issued and outstanding Shares, from time to time, less the number of Shares reserved
for issuance under all other security-based compensation arrangements of the Company, including
the existing Stock Option Plan. On February 9, 2023, the Omnibus Plan was approved by the
shareholders.
b.
The
following table summarizes the number of options granted to directors, officers, employees and consultants under the option plan
for three-month period ended January 31, 2026 and related information:
SUMMARY OF NUMBER OF OPTIONS GRANTED
Number
of options
Weighted
average
exercise
price
Weighted
average
remaining
contractual
term
(in
years)
Aggregate
intrinsic
value
Balance as of July 31, 2025
13,251
$ 896.61
1.62
$ -
Granted (i)
37,700
12.50
4.75
-
Balance as of January
31, 2026
50,951
242.91
3.62
-
Exercisable as of January
31, 2026
22,676
$ 530.22
2.53
$ -
(i)
On
August 1, 2025, the Company granted 37,700 stock options to employees and members of the scientific advisory board at an exercise
price of $ 12.50 per share. All options vest quarterly over two years. The options expire on August 1, 2030. The grant-date fair value
of the award was $ 218,784 . The fair value of options granted during the six-month period ended January 31, 2026 was estimated using
the Black-Scholes option-pricing model with the following weighted-average assumptions: expected volatility of 116 %, expected term
of 5.0 years, risk-free interest rate of 3.98 %, dividend yield of 0 %, and a stock price of $ 7.50 on the grant date.
As
of January 31, 2026, there were $ 1,448,754
of total unrecognized share-based compensation costs related to stock options, restricted share units (RSUs), and performance share
units (PSUs) that are expected to be recognized over a period of up to 2.50
years.
15
BriaCell
Therapeutics Corp
Notes
to the Condensed Consolidated Financial Statements
(Unaudited,
expressed in US Dollars, except share and per share data and unless otherwise indicated)
NOTE
7: SHARE-BASED COMPENSATION (Cont.)
c.
The
following table summarizes information about the Company’s outstanding and exercisable options granted to employees as of January
31, 2026
SCHEDULE OF OUTSTANDING AND EXERCISABLE OPTIONS
Exercise
price
Options
outstanding
as of
January 31, 2026
Weighted
average
remaining
contractual
term
(years)
Options
exercisable
as of
January 31, 2026
Weighted
average
remaining
contractual
term
(years)
Expiry
Date
$ 12.50
37,700
4.50
9,425
4.50
August 1, 2030
$ 60.00
333
3.95
333
3.95
January 16, 2030
$ 904.50
2,663
2.39
2,663
2.39
June 20, 2028
$ 1,074.00
136
2.08
136
2.08
February 27, 2028
$ 907.97
1,195
1.51
1,195
1.51
August 2, 2027
$ 706.50
206
1.31
206
1.31
May 20, 2027
$ 1,126.50
1,000
1.04
1,000
1.04
February 16, 2027
$ 1,270.50
3,160
0.95
3,160
0.95
January 13, 2027
$ 1,074.83
81
0.75
81
0.75
November 1, 2026
$ 636.00
400
0.22
400
0.22
April 19, 2026
$ 636.00
4,077
0.16
4,077
0.16
March 29, 2026
50,951
22,676
d.
As
result of the Arrangement, 2,131,400 BriaPro Options were issued and are outstanding as of January 31, 2026:
SCHEDULE OF OUTSTANDING AND EXERCISABLE OPTIONS
Exercise
Price
Options
outstanding
as
of
January
31, 2026
Options
exercisable
as
of
January
31, 2026
Expiry
Date
$ 0.0933
440,000
440,000
June 20, 2028
$ 0.1108
21,000
21,000
February 27, 2028
$ 0.0984
180,100
180,100
August 2, 2027
$ 0.0729
31,000
31,000
May 20, 2027
$ 0.1162
150,000
150,000
February 16, 2027
$ 0.1310
524,700
524,700
January 13, 2027
$ 0.1165
12,600
12,600
November 1, 2026
$ 0.0888
100,000
100,000
September 1, 2026
$ 0.0656
60,000
60,000
April 19, 2026
$ 0.0656
612,000
612,000
March 29, 2026
2,131,400
2,131,400
e.
Restricted
Share Units
The
following table summarizes the number of RSU’s granted to directors under the Omnibus Plan for three-month period ended January
31, 2026:
SCHEDULE OF RESTRICTED STOCK UNITS GRANTED
Number
of
RSU’s
Aggregate
outstanding
intrinsic
value
Balance,
July 31, 2025
-
$ -
Granted (i)
40,000
376,000
Balance,
January 31, 2026
40,000
$ 172,000
(i)
On
September 24, 2025, the Company granted 40,000 RSUs to directors under the Omnibus Plan. These RSUs vest in full on the earlier of
September 23, 2028 or the occurrence of a change of control, resignation, or dismissal without cause. The grant-date fair value of
these RSUs was $ 376,000 .
16
BriaCell
Therapeutics Corp
Notes
to the Condensed Consolidated Financial Statements
(Unaudited,
expressed in US Dollars, except share and per share data and unless otherwise indicated)
NOTE
7: SHARE-BASED COMPENSATION (Cont.)
f.
Performance Share Units
The
following table summarizes the number of PSU’s granted under the Omnibus Plan for three-month period ended January 31,
2026:
SCHEDULE OF PERFORMANCE SHARE UNITS GRANTED
Number
of
PSU’s
Aggregate
outstanding
intrinsic
value
Balance,
July 31, 2025
-
$ -
Granted (i)
165,935
1,434,513
Balance,
January 31, 2026
165,935
$ 713,521
(i)
On
August 1, 2025, the Company granted 165,935 performance-based stock units (“PSUs”)
to the Chief Executive Officer (“CEO”), Chief Financial Officer (“CFO”),
Chief Medical Officer (“CMO”), and Chief Scientific Officer (“CSO”)
under the Omnibus Plan. These PSUs contain performance conditions tied to the advancement
of the Company’s Bria-IMT Phase 3 program, the Bria-OTS program, and certain corporate
and governance objectives. The grant-date fair value of the PSUs awarded to these officers
totaled $ 353,228 . The PSUs awarded to the CMO and CSO include milestones related to the Bria-OTS
program, with grant-date fair values of $ 70,643 each. The CFO’s PSUs relate to corporate
and financial reporting objectives, with a grant-date fair value of $ 70,643 .
On
September 24, 2025, the Company granted 100,000 PSUs to a director under the Omnibus Plan. These PSUs contain performance conditions
related to the Company’s corporate, strategic, and governance objectives. The grant-date fair value of this award was $ 940,000 ,
determined using the closing price of the Company’s common stock on the grant date.
The
fair value of all PSU awards was determined using the closing price of the Company’s common stock on the respective grant dates.
In accordance with ASC 718, management evaluates the probability of achieving each performance condition at each reporting date.
As of January 31, 2026, management has determined that achievement of the applicable performance conditions remains probable. Compensation
cost is recognized over the requisite service period on a graded vesting (tranche-by-tranche) basis.
During
the six-month period ended January 31, 2026, the Company achieved the performance condition related to the CFO’s PSU’s. As a result, 1,177 PSUs granted to the CFO vested and became issuable during the
period.
g.
The
total share-based compensation expense related to all of the Company’s equity-based awards, recognized for the three and six-month
period ended January 31, 2026 and 2025 is comprised as follows:
SCHEDULE OF SHARE-BASED COMPENSATION EXPENSES
2026
2025
2026
2025
Three
months ended
January 31,
Six
months ended
January 31,
2026
2025
2026
2025
(Unaudited)
(Unaudited)
(Unaudited)
(Unaudited)
Research, development,
and clinical trial expenses
$ 79,016
50,839
$ 162,447
83,557
General
and administrative expenses
206,840
234,254
418,095
468,507
Total
share-based compensation
$ 285,856
285,093
$ 580,542
552,064
NOTE
8: FINANCIAL INCOME, NET
SCHEDULE OF FINANCIAL INCOME , NET
2026
2025
2026
2025
Three
months ended
January
31,
Six
months ended
January 31,
2026
2025
2026
2025
(Unaudited)
(Unaudited)
(Unaudited)
(Unaudited)
Interest income
$ 105,638
46,832
$ 243,607
59,882
Foreign
exchange gain (loss)
( 21,049 )
20,526
( 372 )
19,190
Financial
income, net
$ 84,589
$ 67,358
$ 243,235
$ 79,072
NOTE 9: RESEARCH, DEVELOPMENT, AND CLINICAL TRIAL EXPENSES, NET
(i)
On
August 25, 2025, the Company announced that it had been awarded a $ 2.0 million Small Business Innovation Research (SBIR) grant from
the National Cancer Institute (“NCI”) to support the advancement of Bria-PROS+™ for the treatment of prostate cancer.
The grant provides non-dilutive funding intended to support manufacturing activities and planned clinical evaluation of the program.
The
grant reimburses certain qualifying research and development expenditures incurred by the Company in connection with the program.
In accordance with the Company’s accounting policy for government assistance, amounts received under the grant are recognized
as a reduction of research and development expenses in the period in which the related costs are incurred.
During
the three and six months ended January 31, 2026, the Company received $ 733,815 and $ 826,158 , respectively, under the SBIR grant and
recorded this amount as a reduction of research and development expenses in the condensed consolidated statements of operations.
As
of January 31, 2026, the Company may receive up to an additional $ 1.2 million under the grant, subject to the achievement of certain
research objectives and compliance with the grant terms.
NOTE
10: SUBSEQUENT EVENTS
(i)
On
February 1, 2026, the Company granted an aggregate of 291,000 stock options to directors, executive officers, employees and scientific
advisory board members under the Omnibus Plan. The stock options have an exercise price of US$ 5.59 , vest in equal quarterly installments
beginning May 1, 2026, and expire on February 1, 2031.
(ii)
On
February 18, 2026, the Company and BriaPro, announced that they have entered into a definitive purchase agreement (the “Purchase
Agreement”) pursuant to which BriaPro has agreed to purchase BriaCell’s exclusive license to develop and commercialize
Soluble CD80 (“sCD80”) as a biologic agent for the treatment of cancer and other associated assets (the “Transaction”).
Under
the terms of the Purchase Agreement, BriaPro gains the worldwide rights to develop and commercialize sCD80 as a therapeutic agent
for the treatment of cancer, while UMBC holds all rights, title and interest in the inventions and the patent, except for certain
rights retained by the United States Government. BriaPro will pay 2% royalties to UMBC upon the commercialization of the product
plus other development costs.
As
part of the Transaction, BriaCell will make available to BriaPro up to $ 3 million to fund research and development efforts (the
“Credit Facility”). Each drawdown under the Credit Facility will be subject to BriaCell’s approval regarding the
use of funds.
As
consideration for the transfer of the exclusive license and the Credit Facility, BriaPro will issue to BriaCell 23,972,589 Common
Shares at an aggregate value of approximately C$ 1.18 M, increasing BriaCell’s interest in BriaPro to approximately 78% post-transaction.
The Transaction is expected to close by the end of March 2026, subject to certain conditions including (i) approval
of the disinterested shareholders of BriaPro, and (ii) receipt of a third-party valuation confirming that the Transaction is
occurring at fair market value.
In
accordance with Multilateral Instrument 61-101 – Protection of Minority Security
Holders in Special Transactions (“MI 61-101”), the resolution approving the Purchase
Agreement must be approved by a simple majority of votes cast by shareholders, present in person or represented by proxy and entitled
to vote at the Meeting, excluding the votes cast by any “interested party” (as defined in MI 61-101). As a 10% shareholder
with an interest in the Transaction, BriaCell's shareholdings in BriaPro will be excluded from voting.
On
March 5, 2026, the disinterested shareholders of BriaPro approved the Transaction.
17
Item
2. Management’s Discussion and Analysis of Financial Condition and Results of Operations.
References
to the “Company,” “our,” “us” or “we” refer to BriaCell Therapeutics Corp. The following
discussion and analysis of the Company’s financial condition and results of operations should be read in conjunction with the unaudited
condensed consolidated financial statements and the notes thereto contained elsewhere in this report. Certain information contained in
the discussion and analysis set forth below includes forward-looking statements that involve risks and uncertainties.
Introduction
This
Management’s Discussion and Analysis (“MD&A”) should be read together with other information, including our unaudited
condensed interim consolidated financial statements and the related notes to those statements included in Part I, Item 1 of this Quarterly
Report (the “Condensed Consolidated Financial Statements”), our consolidated financial statements appearing in our Annual
Report on Form 10-K for the year ended July 31, 2025 (the “Annual Report”) and Part I, Item 1A, Risk Factors, of the Annual
Report. This MD&A provides additional information on our business, recent developments, financial condition, cash flows and results
of operations, and is organized as follows:
●
Part
1 - Business Overview. This section provides a general description of our business, which we believe is important in understanding
the results of our operations, financial condition, and potential future trends.
●
Part
2 - Results of Operations . This section provides an analysis of our results of operations for the first half and second quarter
of fiscal 2026 in comparison to the first half and second quarter of fiscal 2025.
●
Part
3 - Financial Liquidity and Capital Resources. This section provides an analysis of our cash flows and outstanding debt and commitments.
Included in this analysis is a discussion of the amount of financial capacity available to fund our ongoing operations and future
commitments.
We
prepare and report our unaudited Condensed Consolidated Financial Statements in accordance with U.S. GAAP. Our unaudited Condensed Consolidated
Financial Statements, and the financial information contained herein, are reported in U.S Dollars.
Cautionary
Note Regarding Forward-Looking Statements
This
Quarterly Report on Form 10-Q includes forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as
amended, and Section 21E of the Exchange Act. We have based these forward-looking statements on our current expectations and projections
about future events. These forward-looking statements are subject to known and unknown risks, uncertainties and assumptions about us
that may cause our actual results, levels of activity, performance or achievements to be materially different from any future results,
levels of activity, performance or achievements expressed or implied by such forward-looking statements. In some cases, you can identify
forward-looking statements by terminology such as “may,” “should,” “could,” “would,”
“expect,” “plan,” “anticipate,” “believe,” “estimate,” “continue,”
or the negative of such terms or other similar expressions. Factors that might cause or contribute to such a discrepancy include, but
are not limited to, those described in our other SEC filings.
Overview
BriaCell
Therapeutics Corp. (“Briacell” or the “Company”) is a clinical-stage biotechnology company that is developing
novel immunotherapies to transform cancer care. Immunotherapies have come to the forefront in the fight against cancer as they harness
the body’s own immune system to recognize and destroy cancer cells. The Company is currently advancing its Bria-IMT™ targeted
immunotherapy in combination with an immune check point inhibitor (Retifanlimab) in a pivotal 1 Phase 3 study in metastatic
breast cancer (listed on ClinicalTrials.gov as NCT06072612 ). Bria-IMT™ is currently under Fast Track Designation
by the U.S. Food and Drug Administration (the “FDA”) intended to accelerate the review process of novel treatments that address
unmet medical needs. Positive completion of the pivotal study, following review by FDA, could lead to full approval of the Bria-IMT™
immune checkpoint inhibitor combination in metastatic breast cancer.
BriaCell
has reported benchmark-beating patient survival and clinical benefit in metastatic breast cancer with median overall survival of 13.4
months in BriaCell’s metastatic breast cancer patients vs. 6.7-9.8 months 2 for similar patients reported in the literature
in its Phase 2 study of Bria-IMT™ combination study with retifanlimab. Additionally, BriaCell reported median overall survival
of 16.5 months in Phase 2 Bria-IMT™ study patients treated in combination with immune checkpoint inhibitor in patients treated
with the Phase 3 formulation since 2022 (post-COVID). A completed Bria-IMT™ Phase 1/2 combination study with retifanlimab (an anti-PD1
antibody manufactured by Incyte) confirmed tolerability and early-stage efficacy (listed on ClinicalTrials.gov as NCT03328026 ).
BriaCell
Phase 1/2 Study of Bria-OTS™, BriaCell’s personalized off-the-shelf immunotherapy, also known as Bria-BRES™, in metastatic
breast cancer is ongoing (listed on ClinicalTrials.gov as NCT06471673 ). The first patient treated with 4 inoculations of
cells (single agent) demonstrated complete resolution of a lung metastasis.
BriaCell
is currently developing Bria-OTS™ and its advanced form, Bria-OTS+™, as a platform technology for personalized off-the-shelf
immunotherapies for numerous types of cancer. The Company announced BriaCell had received positive feedback from its Pre-Investigational
New Drug Application (Pre-IND) meeting with FDA for Bria-PROS+™ for prostate cancer.
18
Recent
Developments
During
the period from August 1, 2025 through to the date of this report, we announced a number of corporate, financing and R&D developments.
On August 21, 2025, our board approved a consolidation of the Company’s issued and outstanding common shares on the basis of one
post-consolidation common share for every ten pre-consolidation common shares, primarily to help ensure continued compliance with Nasdaq
Capital Market listing requirements. The consolidation became effective on August 25, 2025, with the post-consolidation common shares
commencing trading on the Toronto Stock Exchange and Nasdaq on that date.
Throughout this time period, there
were several important updated on the ongoing pivotal Phase 3 study of Bria-IMT™ in patients with advanced metastatic breast cancer,
including accelerating enrollment, adding additional clinical sites, and several positive Data Safety Monitoring Board meetings. Some
of these are detailed below.
We
also strengthened our non-dilutive funding and external collaborations. On August 13, 2025, we announced acceptance into Memorial Sloan
Kettering Cancer Center’s (MSK’s) 2025 Therapeutics Accelerator Cohort program for the Bria-OTS+™ platform, which includes
the Bria-BRES+™ product candidate for breast cancer.
On
August 25, 2025, we reported that we had been awarded a US$2.0 million Small Business Innovation Research (SBIR) grant from the U.S.
National Cancer Institute (NCI) to advance Bria-PROS+™ in prostate cancer, providing non-dilutive funding to support manufacturing
and planned clinical evaluation activities for this program
On
October 21, 2025, we further announced a collaboration with MSK’s Therapeutics Accelerator program focused on the Bria-OTS+ platform.
The collaboration includes support for manufacturing, IND development and clinical protocol work for a planned Phase 1 study of Bria-BRES+
in breast cancer, and is intended to help accelerate clinical development of Bria-OTS+ across multiple cancer indications.
Bria-IMT™
On
November 25, 2025, BriaCell highlighted positive Phase 2 & Phase 3 clinical data at SABCS® 2025 with poster presentations at
the San Antonio Breast Cancer Symposium (December 10, 2025) will highlight positive Phase 2 safety and efficacy signals and positive
biomarker findings in both the Phase 2 and the pivotal Phase 3 studies.On December 9 , 2025, BriaCell announced that patient
enrollment is on track for 1H2026 topline data readout with over 230 patients screened and over 160 patients enrolled in BriaCell’s
pivotal Phase 3 study in metastatic breast cancer (MBC).
Presentation
Title: Survival Results of Phase II Bria-IMT Allogenic Whole Cell-Based Cancer Vaccine
Maturing
positive Phase 2 data continue to support the potentially meaningful clinical benefit of the Bria-IMT regimen and the ongoing pivotal
Phase 3 study is further evaluating this immunotherapy and the role of biomarkers in predicting patient response.
Presentation
Title: Th1-biased cytokine signatures as biomarkers of clinical benefit following SV-BR-1-GM cancer vaccination in breast cancer. BriaCell’s
data suggests that Th1 biased cytokines and chemokines may serve as potential predictive biomarkers of clinical responses to the Bria-IMT
regimen in metastatic breast cancer.
Copies
of the posters are available at https://briacell.com/scientific-publications/ .
On
December 10, 2025, BriaCell presented three posters highlighting robust survival and clinical benefit data in Phase 2, plus positive
key biomarker data from the pivotal Phase 3 study of Bria-IMT™ plus immune check point inhibitor (CPI) at the San Antonio Breast
Cancer Symposium (SABCS®) 2025. Data from the Phase 3 study continues to support biomarkers to identify patients who benefit from
treatment with BriaCell’s regimen. Additionally, maturing Phase 2 study data continues to support meaningful clinical benefit of
the Bria-IMT regimen with outstanding long-term survival. Importantly, no toxicity related discontinuations was reported in the Phase
3 study. Summaries of the studies are shown here.
On
December 18, 2025, BriaCell announced that its Phase 3 Bria-IMT™ clinical trial in metastatic breast cancer was prominently and
independently featured in the Nature Medicine Year In Review’s publication, “ Eleven clinical trials that will shape medicine
in 2026”. Nature Medicine asked leading researchers to name their top clinical trial for 2026, from long-awaited vaccines for infectious
diseases to new treatments for advanced cancers and long COVID. BriaCell’s Phase 3 clinical trial in metastatic breast cancer featured
as “clinical trial to watch in 2026”
On
January 27, 2026, BriaCell Highlighted extended >18-47 months survival in Phase 2 metastatic breast cancer patients. 9 of 25 BriaCell
patients treated since 2022 remained alive >18-47 months post enrollment, markedly exceeding benchmarks reported for standard of care
therapies in similar patient populations. No Bria-IMT™ related discontinuations was reported to that date. Bria-IMT regimen continues
under Fast Track Designation from US FDA.
19
New
positive Phase 2 survival data highlighted multiple patients surpassing expected benchmarks for metastatic breast cancer and survival
length over 18 months in 9 cases as of their last assessment.
Table
1: Ongoing Long-Term Survivors
Patient/Subtype
Months Since Study Start
Age
Number of Prior Regimens
Cycles of Bria-IMT
01-009/ER+/PR+/HER2low
47
74
5
14
07-001/ER+/PR+/HER2low
30
55
7
8
15-001/ER+/PR-/HER2-
30
62
3
12
11-018/ER+/PR+/HER2+
(Highlighted below)
27
66
8; including ENHERTU
35
15-005/ER+/PR+/HER2-
(Highlighted below)
27
44
5
6
15-006/ER+/PR-/HER2-
(Highlighted below)
25
64
8; including TRODELVY
4
15-004/ER+/PR+/HER2-
25
50
3
6
11-019/ER+/PR+/HER2low
23
63
9; including TRODELVY
6
07-014/ER+/PR+/HER2low
>18
62
9; including TRODELVY
5
Note
that Trodelvy and Enhertu are antibody-drug conjugates recently approved for late-stage breast cancer.
Table
2: Comparable analysis of 1- and 2-year survival for the BriaCell Phase 2 study using the Phase 3 formulation since 2022 independent
of subsequent treatment
Breast cancer
Median prior
Median OS
% Survival at:
Reference
type
lines of therapy
(months)
1 year
2 years
Bria-IMT ™ plus CPI
All types
61% HR+
33% TNBC
6% HER2+
6
15.6
52 %
32%
Cortes et al. 1
All types
57% HR+
18-19% TNBC
18-20% HER2+
4
9.1-9.3
~38-40%
7-14%
Kazmi et al. 2
All types
51-52% HR+
25-29% TNBC
9-24% HER2+
2
7.2-9.8
30-38%
11.9-14%
Bardia et al. (TPC) 3
TNBC
4
6.9
~23%
6%
Bardia et al. (Trodelvy) 3
TNBC
4
11.8
50%
21%
Rugo et al (TPC) 4
HR+ HER2-
4
11.2
47%
21%
Rugo et al (Trodelvy) 4
HR+ HER2-
4
14.4
60%
25%
1.
Cortes J, et al. Annals of Oncology 2018 (estimated from Kaplan-Meier curve)
2.
Kazmi S, et al. Breast Cancer Res Treat. 2020
3.
Bardia A, et al. J Clin Oncol. 2024 (estimated from Kaplan-Meier curve)
4.
Rugo HS, et al. The Lancet. 2023 (estimated from Kaplan-Meier curve)
Abbreviations:
HR+:
hormone receptor-positive
TNBC:
Triple-negative breast cancer (lacks or has low levels of the estrogen receptor, progesterone receptor, and human epidermal growth factor
receptor 2 (HER2))
HER2+:
Human epidermal growth factor receptor 2 positive
HR+
HER2-: hormone receptor-positive and human epidermal growth factor receptor 2 negative
TPC:
Treatment of Physicians Choice
On
January 28, 2026, BriaCell reported patients’ images showing regression and resolution of metastasized tumors and immune activation
in patients with orbital (eye), temporal lobe (brain), liver, and spinal involvement. Survival details on these and other select patients
in its Phase 2 study, along with comparable populations, were previously reported.
Images
below confirm clinical responses seen in patients with metastatic orbital (eye), temporal (brain), liver, and spine lesions.
20
Example
1: Patient 11-018
A
66-year-old woman with ER+/PR+/HER2+ metastatic breast cancer, heavily pretreated with 8 prior lines of therapy, including an antibody-drug
conjugate (Enhertu), remains alive 27 months post-enrollment. At baseline, she presented with metastatic involvement of the right orbit
(behind the eye), right temporal lobe of the brain and multiple skeletal sites. Following treatment, she achieved complete resolution
of the temporal lobe metastasis, substantial improvement in the orbital lesion and stable disease in the bone. She remained on study
for 26 months after initiating treatment and receiving 35 cycles of therapy. Images though 20 months for this patient have been previously
described (link). Shown here are updated images through 2 years with measurements superimposed (through 18 months for the temporal lobe
brain metastases).
Example
1 Images ( Patient 11-018) : Bria-IMT treatment resulted in complete resolution of the right temporal lobe lesion and continued
regression of the right orbital (behind the eye) tumor. Measurements of lesion sizes are shown.
LA
= long axis. SA = short axis.
Example
2: Patient 15-005 :
A
44-year-old woman with ER+/PR+/HER2- metastatic breast cancer, previously treated with 5 prior lines of therapy. At baseline, she presented
with metastases to the spine. She completed 6 cycles of therapy achieving stable disease as her best response and remains in survival
follow-up 27 months after study entry.
Before
BriaCell Treatment Image A : CD8 ImmunoPET image
Pre-treatment
imaging of cervical (neck) lymph nodes with moderate uptake indicating presence of some CD8+ cytotoxic (“killer”) T cells.
After
BriaCell Treatment Image B : CD8 ImmunoPET image
Post
treatment enhancement of cervical (neck) lymph nodes indicating immune system activation and increased presence of CD8+ cytotoxic T cells.
Example
2 Images ( Patient 15-005) : CD8 ImmunoPET images pre (A) and post (B) Bria-IMT treatment
Example
3: Patient 15-006 :
A
64-year-old woman with ER+/PR-/HER2- metastatic breast cancer, heavily pre-treated with 8 prior lines of therapy, including the antibody-drug
conjugate Trodelvy, remains alive 25 months post-enrollment. At baseline, presented with hepatic metastasis.
Before
BriaCell Treatment Image A : A liver metastasis (lower arrow) is “cold,” indicating minimal to no CD8+ cytotoxic T cells
in the tumor while enlarged lymph nodes (upper arrow) show moderate uptake.
After
BriaCell Treatment Image B : Swelling (induration) around the metastasis (lower arrow) demonstrates the liver metastasis has become
“hot”, indicating marked CD8+ cytotoxic T cell infiltration while further lymph node enlargement is consistent with increased
activity (upper arrow) indicating increased CD8+ T cells.
21
Example
3 Images ( Patient 15-006) : Combined MRI and CD8 ImmunoPET images Pre (A) and Post (B) Bria-IMT treatment
The
Phase 2 study enrolled 54 heavily pre-treated metastatic breast cancer patients (median six prior therapies) who received the Bria-IMT
regimen plus a checkpoint inhibitor. Of these, 37 patients were treated with the same formulation now being evaluated in the pivotal
Phase 3 study (NCT06072612). Significantly, no Bria-IMT related discontinuations have been reported to date.No Bria-IMT™ related
discontinuations reported to date. Bria-IMT regimen continues under Fast Track Designation from US FDA.
Bria-OTS
and Bria-OTS+
On
November 7, 2025, BriaCell presented robust anti-cancer activity of Bria-OTS+ in breast and prostate cancer models at the Society for
Immunotherapy of Cancer (SITC) 2025. Bria-OTS+ represents a novel, cost-effective, off-the-shelf potent next generation cancer therapy
platform. Next generation Bria-OTS+ platform demonstrated rapid, potent and durable anti-cancer activity by activating both innate and
adaptive immune responses. Increased tumor cell cytotoxicity induced by both Bria-BRES+™ (breast cancer) and Bria-PROS+™
(prostate cancer) was reported. In summary, preclinical data reinforces broad potential of Bria-OTS+ platform across multiple indications.
BriaCell added that lead candidates Bria-BRES+ (breast cancer) and Bria-PROS+ (prostate cancer) are completing GMP manufacturing for
planned clinical trials. As a reminder, $2 million National Cancer Institute (NCI) Small Business Innovative Research (SBIR) award supports
manufacturing and planned clinical evaluation of Bria-PROS+.
On
January 13, 2026, BriaCell reported sustained complete resolution of lung metastasis in Bria-OTS Patient (Figure 1 as shown below). 11-month
sustained complete resolution of lung metastasis was observed in Bria-OTS Phase 1/2a metastatic breast cancer study. No treatment limiting
toxicities reported. The patient maintained stable disease at all other evaluable sites.
Figure
1: Treatment with Bria-OTS monotherapy resulted in 100% resolution of tumor in the right lung of the metastatic breast cancer (MBC) patient
following 2 months of therapy and confirmed at 4, 6, and 11 months of therapy 1 (axial and coronal views)
22
BriaPro
On February
18, 2026, the Company and BriaPro Therapeutics Corp. (“ BriaPro ”), a announced that we have entered into a definitive
purchase agreement (the “ Purchase Agreement ”) pursuant to which BriaPro has agreed to purchase BriaCell’s exclusive
license to develop and commercialize Soluble CD80 (“ sCD80 ”) as a biologic agent for the treatment of cancer and other
associated assets (the “ Transaction ”).
Background
BriaCell originally secured
the exclusive license from the University of Maryland, Baltimore County (“ UMBC ”) on August 2, 2022. The novel
technology, originally developed by Suzanne Ostrand-Rosenberg, Ph.D., Emeritus Faculty at UMBC, and member of BriaCell’s scientific
advisory board, is titled “Soluble CD80 as a Therapeutic to Reverse Immune Suppression in Cancer Patients” and is covered
under USPN 8,956,619 B2, USPN 9,650,429 B2, and USPN 10,377,810 B2. In animal models, sCD80 was well-tolerated and stopped
tumor growth by potentially restoring natural anti-tumor immunity (see Lucas A Horn, et al. and Samuel T Haile et al. in
collaboration with Dr. Ostrand-Rosenberg). Additionally, strong anti-tumor activity of sCD80 has been reported in multiple tumor types
(see Lucas A Horn, et al.). Importantly, as demonstrated in the same studies, sCD80’s unique actions may involve both awakening
and boosting the immune system to recognize and destroy tumor cells.
The Transaction
Under the
terms of the Purchase Agreement, BriaPro gains the worldwide rights to develop and commercialize sCD80 as a therapeutic agent for the
treatment of cancer, while UMBC holds all rights, title and interest in the inventions and the patent, except for certain rights retained
by the United States Government. BriaPro will pay 2% royalties to UMBC upon the commercialization of the product plus other development
costs.
As part of the Transaction,
BriaCell will make available to BriaPro up to $3 million to fund research and development efforts (the “ Credit Facility ”).
Each drawdown under the Credit Facility will be subject to BriaCell’s approval regarding the use of funds.
As consideration
for the transfer of the exclusive license and the Credit Facility, BriaPro will issue to BriaCell 23,972,589 Common Shares at an aggregate
value of approximately C$1.18M, increasing BriaCell’s interest in BriaPro to approximately 78% post-transaction. The Transaction
is expected to close by the end of March 2026, subject to certain conditions including (i) approval of the disinterested
shareholders of BriaPro, and (ii) receipt of a third-party valuation confirming that the Transaction is occurring at fair market
value.
Shareholder Approval
In accordance
with Multilateral Instrument 61-101 – Protection of Minority Security Holders in Special Transactions (“ MI
61-101 ”), the resolution approving the Purchase Agreement must be approved by a simple majority of votes cast by shareholders,
present in person or represented by proxy and entitled to vote at the Meeting, excluding the votes cast by any “interested party”
(as defined in MI 61-101). As a 10% shareholder with an interest in the Transaction, BriaCell's shareholdings in BriaPro will be excluded
from voting.
Formal Valuation Requirements
In respect
of the formal valuation requirement of MI 61-101, BriaPro intends to rely on the specified markets exemptions set forth in subsection
5.5(b) of MI 61-101, as none of its securities are listed or quoted on a specified senior exchange.
Though a
formal valuation is not required under applicable securities laws, as a matter of good governance and best corporate practice, BriaPro
intends to obtain a valuation from an independent third-party valuator as a condition to closing, verifying and validating that Transaction
is occurring at fair market value.
On March 5, 2026, the disinterested shareholders of BriaPro approved the Transaction.
Results
of Operations for the Three and Six Months Ended January 31, 2026, and 2025
Three months ended January 31,
2026
2025
(Unaudited)
(Unaudited)
Operating expenses:
Research and development expenses
$
6,053,689
5,684,777
General and administrative expenses
1,477,577
1,484,666
Total operating expenses
7,531,266
7,169,443
Operating loss
(7,531,266
)
(7,169,443
)
Financial income, net
84,589
67,358
Change in fair value of the warrant liability
211,777
806,841
Share of loss on equity investment
(61,993
)
(42,584
)
Net loss for the period
$
(7,296,893
)
$
(6,337,828
)
Net loss attributable to non-controlling interest
(75,073
)
(46,408
)
Net loss for the period attributable to BriaCell
(7,221,820
)
(6,291,420
)
Net loss per share attributable to BriaCell – basic and diluted
$
(2.58
)
$
(23.31
)
Weighted average number of shares used in computing net basic and diluted earnings per share of common stock
2,802,337
269,957
23
Research
and Development Costs
Research
costs are comprised primarily of (i) salaries and wages to Company employees at our laboratory and (ii) clinical trials and investigational
drug costs, which include the testing and manufacture of our investigational drugs and costs of our clinical trials.
The
following is a breakdown of our research and development costs by nature of expenses:
Three
months ended January 31,
2026
2025
(Unaudited)
(Unaudited)
Clinical trial
sites and investigational drug costs
$ 3,799,523
$ 4,117,576
Wages and salaries
1,881,893
1,292,021
Laboratory Rent
130,500
114,330
Supplies
134,974
85,264
Depreciation
22,839
22,839
Professional fees
4,944
1,908
Share-based
compensation
79,016
50,839
$ 6,053,689
$ 5,684,777
For
the three-month period ended January 31, 2026, total research and development expenses were $6,053,689, compared to $5,684,777 for
the three-month period ended January 31, 2025. Clinical trial sites and investigational drug costs decreased modestly year over
year, primarily reflecting decreased reliance of third-party vendors in our trials as we expand our in-house headcount to advance
our trials, which also explains the increase in wages and salaries as detailed below. The increase in total research and development
expenses was primarily driven by wages and salaries, which rose from $1,292,021 in 2025 to $1,881,893 in 2026, reflecting higher
headcount and additional personnel required to support clinical operations and ongoing development programs. Laboratory rent
increased to $130,500 in 2026, compared to $114,330 in 2025, due to expanded utilization of laboratory space and related facility
charges. Supplies increased from $85,264 in 2025 to $134,974 in 2026, reflecting increased consumable usage driven by greater
clinical and laboratory activity during the current period. Depreciation expense was consistent year over year at $22,839 for both
periods. Professional fees increased from $1,908 in 2025 to $4,944 in 2026, primarily due to higher consulting, regulatory, and
scientific support related to advancing clinical development. Share-based compensation increased from $50,839 in 2025 to $79,016 in
2026, reflecting a higher level of equity-based awards outstanding during the period.
Our
clinical trial expenses are broken down as follows:
Three
months ended January 31,
2026
2025
(Unaudited)
(Unaudited)
Bria-IMT™
Pivotal Phase 3 study
$ 3,874,242
$ 3,642,650
Bria-IMT™ Phase 1/2a
197,203
215,301
Bria-OTS™
Phase 1/2a
936,726
65,608
$ 5,008,171
$ 3,923,559
Clinical
trial expenses for the three months ended January 31, 2026, were $5,008,171, compared to $3,923,559 during the same period in 2025. The
increase reflects continued investment in the Bria-IMT™ pivotal Phase 3 program and ongoing advancement of the Bria-OTS™
Phase 1/2a program as it progresses through early clinical development. Together, these programs account for the majority of the year-over-year
increase in clinical trial expenses.
For the three-month
period ended January 31, 2026, Bria-IMT™ Pivotal Phase 3 Study costs were $3,874,242, compared to $3,642,650 in 2025. The increase
reflects the study’s continued progression through an advanced, cost-intensive stage, including expanded patient enrollment, increased
clinical site activity, CRO services, central laboratory work, and clinical supply management. The level of spending is consistent with
maintaining study momentum as the program advances toward planned interim analyses.
For
the three-month period ended January 31, 2026, Bria-IMT™ Phase 1/2a expenses were $197,203, compared to $215,301 in 2025. The decrease
reflects the continued wind-down of the program following completion of primary activities in fiscal 2024, with current-period costs
primarily related to residual close-out procedures, data management, and limited follow-up activities. Expenses are expected to remain
modest as final wrap-up items are completed.
For
the three-month period ended January 31, 2026, Bria-OTS™ Phase 1/2a expenses were $936,726, compared to $65,608 in 2025. The substantial
increase reflects continued advancement of the OTS program in early clinical development. Current-period costs include expanded development
and manufacturing activities, GMP production of Bria-BRES+ and Bria-PROS+, regulatory and analytical support, and operational activities
necessary to support ongoing evaluation of the next-generation Bria-OTS+ platform. The increased investment aligns with the program’s
progression and the expansion of OTS across multiple solid tumor indications.
24
General
and Administrative Expenses
For
the three-month period ended January 31, 2026, general and administrative expenses were $1,477,577, compared to $1,484,666 for the same
period in 2025. The decrease was primarily driven by lower share-based compensation, professional fees, consulting, shareholder communications,
and travel expenses, partially offset by higher wages and salaries, regulatory, filing and transfer agent fees, insurance, and other
general administrative costs.
Financial
income, net
For the three-month period ended January 31, 2026, the Company recorded
net financial income of $84,589, compared to $67,358 in the same period of 2025. The increase is mainly attributable to higher foreign
exchange losses offset by higher interest income. For the three-month period ended January 31, 2026, financial income was comprised of
$105,638 of interest income, and a $21,049 foreign exchange loss.
Profit
(loss) for the period
For the three-month period ended January 31, 2026, the Company reported
a net loss of $7,296,893, compared to $6,337,828 for the same period in 2025. The higher loss primarily reflects higher operating expenses,
including increased research and development spending as the Company continued to advance its pivotal Phase 3 trial, including higher
clinical-site activity, investigational product costs, and supporting operational infrastructure.
Results
of Operations for the Six Months Ended January 31, 2026 and 2025
Six months ended January 31,
2026
2025
(Unaudited)
(Unaudited)
Operating Expenses:
Research, development, and clinical trial expenses
$
12,737,332
$
9,350,118
General and administrative expenses
3,116,877
2,972,157
Total operating expenses
15,854,209
12,322,275
Operating loss
(15,854,209
)
(12,322,275
)
Financial income, net
243,235
79,072
Change in fair value of the warrant liability
142,576
190,198
Share of loss on equity investments
(106,823
)
(114,099
)
Net loss for the period
$
(15,575,221
)
(12,167,104
)
Net loss attributable to non-controlling interest
(155,836
)
(73,509
)
Net loss for the period attributable to BriaCell
(15,419,385
)
(12,093,595
)
Net loss per share attributable to BriaCell – basic and diluted
$
(6.58
)
$
(54.35
)
Weighted average number of shares used in computing net basic earnings per share of common stock
2,343,122
222,498
Weighted average number of shares used in computing net diluted earnings per share of common stock
2,343,122
222,498
25
Research,
Development, and Clinical Trial Costs
Research
costs are comprised primarily of (i) salaries and wages to Company employees at our laboratory; and (ii) Clinical trials and investigational
drug costs, which include the testing and manufacture of our investigational drugs and costs of our clinical trials.
The
following is a breakdown of our research, development, and clinical trial costs by nature of expenses:
Six
months ended January 31,
2026
2025
(Unaudited)
(Unaudited)
Clinical trial
sites and Investigational drug costs
$ 8,662,722
$ 6,557,243
Wages and salaries
3,185,595
2,241,110
Laboratory Rent
255,110
228,660
Supplies
411,631
184,694
Depreciation
45,678
45,678
Professional fees
14,149
9,176
Share-based
compensation
162,447
83,557
$ 12,737,332
$ 9,350,118
For
the six-month period ended January 31, 2026, research, development, and clinical trial expenses were $12,737,332, compared to $9,350,118
for the same period in 2025. The increase was primarily driven by higher clinical trial site and investigational drug costs, which rose
from $6,557,243 in 2025 to $8,662,722 in 2026 as the Company advanced its clinical programs. Wages and salaries increased from $2,241,110
in 2025 to $3,185,595 in 2026, reflecting increased headcount and personnel supporting clinical and development activities. Laboratory
rent increased to $255,110 in 2026 from $228,660 in 2025 due to expanded use of facilities. Supplies increased to $411,631 in 2026 from
$184,694 in 2025, reflecting higher clinical and laboratory activity. Depreciation expense remained consistent year over year at $45,678.
Professional fees increased to $14,149 in 2026 from $9,176 in 2025 due to increased consulting and support for clinical operations. Share-based
compensation increased to $162,447 in 2026 from $83,557 in 2025, reflecting a higher level of equity-based awards outstanding during
the period.
Clinical
trial expenses for the period are as follows:
Six
months ended January 31,
2026
2025
(Unaudited)
(Unaudited)
Bria-IMT™
Pivotal Phase 3 study
$ 7,667,192
$ 6,089,111
Bria-IMT™ Phase 1/2a
360,407
399,343
Bria-OTS™
Phase 1/2a
1,924,764
143,195
$ 9,952,363
$ 6,631,649
Clinical
trial expenses for the six months ended January 31, 2026, were $9,952,363, compared to $6,631,649 during the same period in 2025. The
increase reflects sustained investment in the Bria-IMT™ pivotal Phase 3 program and significant advancement of the Bria-OTS™
Phase 1/2a program as it progresses through early clinical development. These programs continue to be the primary drivers of the year-over-year
increase in clinical trial expenses.
For
the six-month period ended January 31, 2026, Bria-IMT™ Pivotal Phase 3 Study costs were $7,667,192, compared to $6,089,111 in 2025.
The increase reflects continued patient enrollment, expansion of clinical sites, increased clinical site activity, CRO services, central
laboratory testing, and clinical supply management associated with the ongoing progression of the Phase 3 study. Spending levels during
the period are consistent with maintaining operational momentum as the trial advances toward planned interim analyses.
For the six-month period ended
January 31, 2026, Bria-IMT™ Phase 1/2a expenses were $360,407, compared to $399,343 in 2025. The decrease reflects the continued
wind-down of the program following completion of primary activities in fiscal 2024. Current-period costs primarily relate to residual
close-out procedures, data management, and limited follow-up activities. Expenses are expected to decline further as final wrap-up activities
conclude.
For the six-month
period ended January 31, 2026, Bria-OTS™ Phase 1/2a expenses were $1,924,764, compared to $143,195 in 2025. The substantial increase
reflects continued advancement of the OTS program into early clinical development. Costs incurred during the period include expanded
development and manufacturing activities, GMP production of Bria-BRES+ and Bria-PROS+, regulatory and analytical support, and operational
activities necessary to support ongoing evaluation of the next-generation Bria-OTS+ platform. The increased investment aligns with the
program’s progression and expansion across multiple solid tumor indications.
General
and Administrative Expenses
For the six-month period ended January 31, 2026, general and administrative expenses amounted to $3,116,877, compared
to $2,972,157 for the same period in 2025. The increase was primarily driven by higher wages and salaries, regulatory and filing fees,
insurance, and other administrative costs, partially offset by lower consulting, professional fees, and travel expenses.
Financial
income, net
For the six-month period ended January 31, 2026, financial income amounted
to $243,235, compared to $79,072 for the six-month period ended January 31, 2025. Financial income for the 2026 period consisted of $243,607
in interest income and a $372 foreign exchange loss. In comparison, financial income for the 2025 period included $59,882 in interest
income and a $19,190 foreign exchange gain. The increase in financial income from 2025 to 2026 was primarily due to higher interest income,
reflecting increased cash and cash equivalents available for investment in interest-bearing funds.
26
Loss
for the period
The Company reported a loss of $15,575,221 for the six-month period
ended January 31, 2026, compared to $12,167,104 for the same period in 2025. The increase in loss was primarily driven by higher research,
development and clinical trial expenses, which rose to $12,737,332 in 2026 from $9,350,118 in 2025 as the Company advanced its clinical
programs. This was partially offset by higher financial income in the current period, including increased interest income and a lower
foreign exchange loss.
Liquidity,
Capital Resources and Going Concern Uncertainty
The
financial statements have been prepared on a going concern basis, which assumes that the Company will be able to realize its assets and
discharge its liabilities in the normal course of business for the foreseeable future. The continuing operations of the Company are dependent
upon its ability to continue to raise adequate financing and to commence profitable operations in the future.
As of January 31, 2026, the company had a positive working capital
balance of $28,993,334 (July 31, 2025 positive balance of $15,948,588).
As of January 31, 2026, the Company has total assets of $33,594,454
(July 31, 2025 - $ 21,649,706), a positive working capital of $28,993,334 (July 31, 2025 – positive balance of $15,948,588) and
an accumulated deficit of $127,174,949 (July 31, 2025 - negative balance of $ 111,755,564).
As
of January 31, 2026, the Company’s capital resources consist primarily of cash and cash equivalents, comprising mostly
of cash on deposit with banks, investments in money market funds, investments in U.S. government securities, U.S. government agency securities,
and investment grade corporate debt securities . Our investment policy and strategy are focused
on preservation of capital and supporting our liquidity requirements.
Historically,
the Company has financed its operation through private and public placement of equity securities, as well as debt financing. The Company’s
ability to fund its longer-term cash requirements is subject to multiple risks, many of which are beyond its control. The Company intends
to raise additional capital, either through debt or equity financings in order to achieve its business plan objectives. Management believes
that it can be successful in obtaining additional capital; however, there can be no assurance that the Company will be able to do so.
There is no assurance that any funds raised will be sufficient to enable the Company to attain profitable operations or continue as a
going concern. To the extent that the Company is unsuccessful, the Company may need to curtail or cease its operations and implement
a plan to extend payables or reduce overhead until sufficient additional capital is raised to support further operations. There can be
no assurance that such a plan will be successful. To this end, for several months during calendar year 2025, certain directors and officers
agreed to defer payment of their directors’ fees/compensation until we completed a financing, after which, these fees were paid
in full. Further, certain officers have indicated their willingness to receive a portion of their compensation in equity of the Company,
subject to applicable Nasdaq rules. In addition, we continue to reduce expenditure on certain non-core activities whilst maintaining
our focus on our Phase 3 Bria-IMT™ pivotal study in advanced metastatic breast cancer.
27
During the period ended January 31, 2026, the Company’s overall
position of cash and cash equivalents increased by $19,409,820 from the period ended July 31, 2025 (including effects of foreign exchange).
This increase in cash can be attributed to the following:
The Company’s net cash used in operating activities during the
period ended January 31, 2026, was $15,672,094 as compared to $12,875,298 for the period ended January 31, 2025.
Cash
gained in financing activities for the period ended January 31, 2026, was 27,874,441 as compared to 17,176,863 for the period ended January
31, 2025.
Off-Balance
Sheet Arrangements
None.
Tabular
Disclosure of Contractual Obligations
None.
Critical
Accounting Policies and Estimates
There
have been no material changes to our critical accounting policies and estimates from the information provided in the MD&A section
in our Annual Report.
New
Accounting Policies Adopted
The
Company did not adopt any new accounting policies during the period ended January 31, 2026.
Item
3. Quantitative and Qualitative Disclosures About Market Risk.
The
Company’s financial instruments consist of cash and cash equivalents, investments, warrant liability, short term loans, trade payable,
and accrued expenses and other payables. Unless otherwise noted, it is management’s opinion that the Company is not exposed to
significant interest or credit risks arising from these financial instruments. The fair value of these financial instruments approximates
their carrying values, unless otherwise noted.
Management
understands that the Company is exposed to financial risk arising from fluctuations in foreign exchange rates and the degree of volatility
of these rates as a portion of the Company’s transactions occur in Canadian Dollars (mainly costs relating to being a public company
in Canada), and the Company’s functional and presentation currency is the US dollar. The Company does not use derivative instruments
to reduce its exposure to foreign currency risk.
The
Company is exposed in varying degrees to a variety of financial instrument related risks. The Board of Directors approves and monitors
the risk management process. The overall objectives of the Board are to set policies that seek to reduce risk as far as possible without
unduly affecting the Company’s competitiveness and flexibility.
The
type of risk exposure and the way in which such exposure is managed is as follows:
Credit
risk
The
Company has no significant concentration of credit risk arising from operations. Management believes that the credit risk concentration
with respect to financial instruments is remote.
Liquidity
Risk
The Company’s approach to managing liquidity risk is to ensure
that it will have sufficient liquidity to meet liabilities as they come due. As of January 31, 2026, the Company has total assets of $33,594,454
(July 31, 2025 - $21,649,706) and a positive working capital balance of $28,993,334 (July 31, 2025 – positive working capital balance
of $15,948,588).
28
Market
Risk
Interest
rate risk
Interest
Rate risk is the risk that the fair value of a financial instrument will fluctuate because of changes in market interest rates. Loans
payable include both fixed and variable interest rates; however, the Company does not believe it is exposed to material interest rate
risk.
Price
risk
As
the Company has no revenues, price risk is remote.
Exchange
risk
The
Company is exposed to foreign exchange risk as a portion of the Company’s transactions occur in Canadian Dollars (mainly costs
relating to being a public company in Canada) and, therefore, the Company is exposed to foreign currency risk at the end of the reporting
period through its Canadian denominated accounts payable and cash. As of January 31, 2026, a 5% depreciation or appreciation of the Canadian
dollar against the US dollar would not have a material effect on the in total loss and comprehensive loss.
Fair
Values
The
carrying values of cash and cash equivalents, trade payable, warrant liability, short term loans, and accrued expenses and other payables
approximate their fair values due to their short terms to maturity.
Cash
and cash equivalents are valued using quoted market prices in active markets. The fair value of the warrant liability is determined based
on the nature of the warrant. For publicly traded warrants we use the quoted market price and for all other warrants we use the Black-Scholes
pricing model.
Item
4. Controls and Procedures.
Evaluation
of Disclosure Controls and Procedures
We
maintain “disclosure controls and procedures,” as defined in Rule 13a-15(e) and Rule 15d-15(e) under the Exchange Act that
are designed to ensure that information required to be disclosed by a company in the reports that it files or submits under the Exchange
Act is recorded, processed, summarized and reported, within the time periods specified in the SEC’s rules and forms. Disclosure
controls and procedures include, without limitation, controls and procedures designed to ensure that information required to be disclosed
by a company in the reports that it files or submits under the Exchange Act is accumulated and communicated to our management, including
our principal executive and principal financial officers, as appropriate to allow timely decisions regarding required disclosure.
Our
management, with the participation of our principal executive officer and principal accounting and financial officer, has evaluated the
effectiveness of our disclosure controls and procedures (as defined in Rules 13a-15(e) and 15d-15(e) under the Securities Exchange Act
of 1934 under the Securities Exchange Act of 1934, as amended, or the Exchange Act), as of the end of the period covered by this Quarterly
Report on Form 10-Q. Our management recognizes that any controls and procedures, no matter how well designed and operated, can provide
only reasonable assurance of achieving their objectives and our management necessarily applies its judgment in evaluating the cost-benefit
relationship of possible controls and procedures. Based on such evaluation, our principal executive officer and principal accounting
and financial officer have concluded that as of January 31, 2026, our disclosure controls and procedures were effective at the reasonable
assurance level.
Changes
in Internal Control over Financial Reporting
There
have not been material changes in our internal control over financial reporting during the quarter ended January 31, 2026, that have
materially affected, or are reasonably likely to materially affect, our internal control over financial reporting.
29
PART
II - OTHER INFORMATION
Item
1. Legal Proceedings.
None.
Item
1A. Risk Factors.
As
of the date of this Quarterly Report on Form 10-Q, there have been no material changes from the risk factors previously disclosed in
our Annual Report for the year ended July 31, 2025.
Item
2. Unregistered Sales of Equity Securities and Use of Proceeds.
There
were no unregistered sales of equity securities during the six months ended January 31, 2026.
Item
3. Defaults Upon Senior Securities.
None.
Item
4. Mine Safety Disclosures.
Not
Applicable.
Item
5. Other Information.
None.
Item
6. Exhibits
The
following exhibits are filed as part of, or incorporated by reference into, this Quarterly Report on Form 10-Q.
EXHIBIT
INDEX
Exhibit
Description
31.1
Certification of Principal Executive Officer pursuant to Securities Exchange Act Rules 13a-14(a) and 15(d)-14(a), as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002 *
31.2
Certification of Principal Financial Officer pursuant to Securities Exchange Act Rules 13a-14(a) and 15(d)-14(a), as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002 *
32.1
Certification of Principal Executive Officer pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002 *
32.2
Certification of Principal Financial Officer pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002 *
101.INS
Inline
XBRL Instance Document*
101.CAL
Inline
XBRL Taxonomy Extension Calculation Linkbase Document*
101.SCH
Inline
XBRL Taxonomy Extension Schema Document*
101.DEF
Inline
XBRL Taxonomy Extension Definition Linkbase Document*
101.LAB
Inline
XBRL Taxonomy Extension Labels Linkbase Document*
101.PRE
Inline
XBRL Taxonomy Extension Presentation Linkbase Document*
104
Cover
Page Interactive Data File (embedded within the Inline XBRL document)
*
Filed
herewith.
30
SIGNATURES
In
accordance with the requirements of the Exchange Act, the registrant caused this report to be signed on its behalf by the undersigned,
thereunto duly authorized.
BRIACELL
THERAPEUTICS CORP.
March 10, 2026
By:
/s/
William V. Williams
Name:
William
V. Williams
Title:
Chief
Executive Officer
(Principal
Executive Officer)
March 10, 2026
By:
/s/
Gadi Levin
Name:
Gadi
Levin
Title:
Chief
Financial Officer
(Principal
Financial and Accounting Officer )
31
Text extracted from the filing as submitted to EDGAR. Formatting, tables and exhibits are simplified for reading; the original document is authoritative for anything you rely on.