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Item 9A. Controls and Procedures

2025-02-24 compared with 2015-02-23 · 160 added, 247 removed, 48 unchanged (89% of the section changed)

1 unchanged sentence

Evaluation of Disclosure Controls and Procedures

Our management, Chief Executive Officer and Vice President of Finance, evaluated the effectiveness of our disclosure controls and procedures as of December 31, 2014.

The term "disclosure controls and procedures," as defined in Rules 13a-15(e) and 15d-15(e) under the Exchange Act, means controls and other procedures of a company that are designed to ensure that information required to be disclosed by us in the reports that we file or submit under the Exchange Act is recorded, processed, summarized and reported within the time periods specified in the SEC's rules and forms.

Disclosure controls and procedures include, without limitation, controls and procedures designed to ensure that information required to be disclosed by us in the reports that we file or submit under the Exchange Act is accumulated and communicated to our management, including our Chief Executive Officer and Vice President of Finance, as appropriate, to allow timely decisions regarding required disclosure.

Based on this evaluation, and the remediation of the material weakness identified in our internal control over financial reporting as of December 31, 2013, as described below, our Chief Executive Officer and Vice President of Finance concluded that our disclosure controls and procedures were effective as of December 31, 2014 at the reasonable assurance level.

Material Weakness Previously Identified

As previously reported in our annual report on Form 10-K for the year ended December 31, 2013, our independent registered public accounting firm identified a material weakness in our internal control over financial reporting related to revenue recognition as it relates to properly recording negotiated terms and conditions in our product development partnerships and license agreements and the misapplication of GAAP with respect to the timing of the recognition of revenue for such agreements .

These errors arose from control deficiencies that, in the aggregate, could result in a misstatement to the aforementioned account that could result in a material misstatement of our annual or interim financial statements that would not be prevented or detected.

Remediation of Material Weakness

Subsequent to the identification of the material weakness, we improved our controls by increasing the resources in our legal and accounting departments and improving our procedures over review of material contracts.

We have hired an experienced controller and additional staff in the accounting department and we have hired an experienced general counsel to augment our staff for reviewing and filing our public filings.

We have reviewed our existing procedures and policies and updated them and implemented additional procedures and controls over critical accounting areas related to revenue recognition.

We have updated our accounting policies and procedures and documentation of these.

T hese improvements to our internal control infrastructure were implemented over the course of the first three quarters of 2014, and were in place in connection with the preparation of our financial statements for the year ended December 31, 2014.

As such, we believe that the remediation initiative outlined above was sufficient to remediate the material weakness in internal control over financial reporting as discussed above.

Management’s Report on Internal Control Over Financial Reporting

Our m an a ge m ent is respons i ble for e stablish i ng and m a i nt a in i ng ad e qu a te i nt e rn a l con t rol ov e r fin a n c ial reporting ( a s def i ned i n Rule 13a-15(f) a nd 15d-15(f) und e r t he Se c ur i t i es E x c hange Act of 1934, as a m ended).

Our m anag e m e nt, Chi e f Ex e cu t ive Offi c er and Vice President of Finance , a ss e ss e d the e ffe c t i veness of our i nt e rn a l con t rol ov e r fin a n c ial reporting a s of D e c em ber 31, 2014.

In m ak i ng th i s a ss e ss m ent, our m an a g e m e nt used the cr i t e ria s e t forth by t he Co m m i t t ee of Sponsoring Organ i z a t i ons of t he Tre a dway Co m m i ssion (1992 Fr a m e work) ("COSO") in Internal Control—Integrated Framework.

B a sed on th a t assessm e nt a nd us i ng the COSO crit e ri a , our m an a g e m e nt, Chi e f E x e cu t ive Offi c er and Vice

President of Finan ce h a ve con c luded th a t, as of D e c e mb e r 31, 201 4 , our int e rnal c on t rol ov e r fin a nc i al r e por t ing was effe c tive.

T h i s A nnu a l R e p o rt on F orm 10-K do e s not i n c l ude a n a t t e s t a t i on r e port of our r e g i s t e r e d p u b l i c a c c o u n t i ng f i rm d u e t o a t r a n s it i on p e r i od e s t a b l i s h e d by t he J u m p s t a rt O u r B u s i n e s s S ta r t ups A c t , or J O B S A c t , for e me rg i ng gr o w t h c o m p a n i e s .

Our management, Chief Executive Officer and Chief Financial Officer, evaluated the effectiveness of our disclosure controls and procedures as of December 31, 2023.

The term "disclosure controls and procedures" as defined in Rules 13a-15(e) and 15d-15(e) under the Exchange Act, means controls and other procedures of a company that are designed to ensure that information required to be disclosed by us in the reports that we file or submit under the Exchange Act has been appropriately recorded, processed, summarized and reported within the time periods specified in the SEC's rules and forms and that such information is accumulated and communicated to our management, including our Chief Executive Officer and Chief Financial Officer, as appropriate, to allow timely decisions regarding required disclosure.

At the time our Original Form 10-K for the year ended December 31, 2023 was filed on February 29, 2024 our Chief Executive Officer and Chief Financial Officer concluded that our disclosure controls and procedures were effective as of December 31, 2023 at the reasonable assurance level.

Subsequent to the original evaluation, our Chief Executive Officer and Chief Financial Officer concluded that our disclosure controls and procedures were not effective as of December 31, 2023 due to material weaknesses related to the design of controls related to the review of the accounting treatment of the proceeds from the sale of future royalties pursuant to the Ultomiris Royalty Sale Agreement as part of our non-routine transactions and the design of controls related to the evaluation of certain tax legislation, which led to the restatement of our audited financial statements for the year ended December 31, 2023.

For additional information see the Explanatory Note in this Form 10-K/A.

Notwithstanding the conclusion by our Chief Executive Officer and Chief Financial Officer that our controls and procedures were not effective as of December 31, 2023, and notwithstanding the material weaknesses in our internal control over financial reporting described below, our Chief Executive Officer and Chief Financial Officer have concluded that the consolidated financial statements and related financial information included in this Form 10-K/A fairly present in all material respects our financial condition, results of operations and cash flows as of the dates presented, and for the periods ended on such dates, in conformity with GAAP.

Management’s Report on Internal Control over Financial Reporting

Our management is responsible for establishing and maintaining adequate internal control over financial reporting (as defined in Rule 13a-15(f) and 15d-15(f) under the Exchange Act).

Our management, Chief Executive Officer and Chief Financial Officer, assessed the effectiveness of our internal control over financial reporting as of December 31, 2023.

In making this assessment, our management used the criteria set forth by the Committee of Sponsoring Organizations of the Treadway Commission (2013 Framework) (COSO) in Internal Control-Integrated Framework.

Based on that assessment and using the COSO criteria, in preparation of this Form 10-K/A, we identified material weaknesses in our internal control over financial reporting that led to a material misstatement of our audited financial statements.

Based on the existing of these material weaknesses, our management, Chief Executive Officer and Chief Financial Officer concluded that we did not maintain effective internal control over financial reporting as of the end of the period covered by this Form 10-K/A.

A material weakness is a deficiency, or a combination of deficiencies, in internal control over financial reporting, such that there is a reasonable possibility that a material misstatement of the Company's annual or interim financial statements will not be prevented or detected on a timely basis.

Based on our assessment as of December 31, 2023, management concluded that our internal control over financial reporting was not effective due to material weaknesses related to the analysis of non-routine transactions and income taxes.

Due to the material weaknesses described herein, management completed additional procedures prior to filing this on Form 10-K/A.

Management’s Plan for Remediation of Material Weaknesses

As management is responsible for maintaining effective internal control over financial reporting, and for its assessment of the effectiveness of internal control over financial reporting, we understand the importance of developing a resolution plan aligned with management and overseen by the Audit Committee of our Board of Directors.

Since the material weaknesses were identified, management has been implementing and continues to implement measures designed to ensure that control deficiencies contributing to the material weaknesses are remediated, such that these controls are designed, implemented, and operating effectively.

Our plan to address the material weakness related to the design of controls related to the review of the accounting treatment of the proceeds from the sale of future royalties pursuant to the Ultomiris Royalty Sale Agreement includes the following:

(1) implement a more rigorous analysis of non-routine transactions, (2) on highly technical and complex accounting transactions, improve our process to identify and select qualified third-party advisors, and (3) enhance our review of capabilities and work performed by the third-party advisors specifically related to the review of accounting guidance for complex non-routine transactions.

Our plan to address the material weakness related to the design of controls related to the evaluation of certain tax legislation includes:

(1) enhance our review of capabilities and work performed by third-party advisors related to the review of tax advice and (2) on a quarterly basis, review income tax legislative changes and their impact to our financial statements with our tax expert.

We recognize that the material weaknesses in our internal control over financial reporting will not be considered remediated until the remediated controls operate for a sufficient period of time and can be tested and concluded by management to be designed and operating effectively.

We continue to evaluate and work to improve our internal control over financial reporting related to the identified material weaknesses and management may determine to take additional measures to address control deficiencies or determine to modify the remediation plan described above.

In addition, we report the progress and status of the above remediation efforts to the Audit Committee on a periodic basis.

Changes in Internal Control over Financial Reporting

Other than the changes disclosed above regarding the remediation of the previous material weakness, there has been no change in our internal control over financial reporting during the quarter ended December 31, 2014, that has materially affected, or is reasonably likely to materially affect, our internal control over financial reporting.

Other than as outlined above, there has been no change in our internal control over financial reporting during the quarter ended December 31, 2023, that has materially affected, or is reasonably likely to materially affect, our internal control over financial reporting.

Inherent Limitations of Controls

1 unchanged sentence

Controls and procedures, no matter how well designed and operated, can provide only reasonable assurance of achieving their objectives, and management necessarily applies its judgment in evaluating the cost-benefit relationship of possible controls and procedures.

Because of the inherent limitations in all control systems, no evaluation of controls can provide absolute assurance that all control issues and instances of fraud, if any, within the Company have been detected.

Because of the inherent limitations in all

control systems, no evaluation of controls can provide absolute assurance that all control issues and instances of fraud, if any, within the Company have been detected.

These inherent limitations include the realities that judgments in decision-making can be faulty and that breakdowns can occur because of a simple error or mistake.

3 unchanged sentences

Because of the inherent limitations in a cost-effective control system, misstatements due to error or fraud may occur and not be detected.

Other Information

Not applicable.

Directors, Executive Officers and Corporate Governance

We have adopted a code of ethics for directors, officers (including our principal executive officer, principal financial officer and principal accounting officer) and employees, known as the Code of Business Conduct and Ethics.

The Code of Business Conduct and Ethics is available on our website at http://www.xencor.com under the Corporate Governance section of our Investor Relations page.

We will promptly disclose on our website (i) the nature of any amendment to the policy that applies to our principal executive officer, principal financial officer, principal accounting officer or controller, or persons performing similar functions and (ii) the nature of any waiver, including an implicit waiver, from a provision of the policy that is granted to one of these specified individuals that is required to be disclosed pursuant to SEC rules and regulations, the name of such person who is granted the waiver and the date of the waiver.

The other information required by this item and not set forth below will be set forth in the sections headed “Election of Directors”

and “Executive Officers”

in our Proxy Statement for our 2015 Annual Meeting of Stockholders, or Proxy Statement, to be filed with the SEC within 120 days after the end of the fiscal year ended December 31, 2014 , and is incorporated herein by reference.

Executive Compensatio n

The information required by this item will be set forth in the section headed “Executed Compensation”

in our Proxy Statement and is incorporated herein by reference.

Security Ownership of Certain Beneficial Owners and Management and Related Stockholder Matters

The information required by this item will be set forth in the section headed “Security Ownership of Certain Beneficial Owners and Management”

in our Proxy Statement and is incorporated herein by reference.

The information required by Item 201(d) of Regulation S ‑K will be set forth in the section headed “Executive Compensation”

in our Proxy Statement and is incorporated herein by reference.

Certain Relationships and Related Transactions, and Director Independence

The information required by this item will be set forth in the section headed “Transactions With Related Persons”

in our Proxy Statement and is incorporated herein by reference.

Principal Accounting Fees and Services

The information required by this item will be set forth in the section headed “Ratification of Selection of Independent Registered Public Accounting Firm”

in our Proxy Statement and is incorporated herein by reference.

Attestation in Internal Control over Financial Reporting

RSM US LLP, our independent registered public accounting firm, has audited our financial statements for the year ended December 31, 2023 and has issued an audit report on the effectiveness of the Company’s internal control over financial reporting as of December 31, 2023, which is included in Item 8 of this Form 10-K/A.

Exhibits, Financial Statement Schedules

Financial Statements.

We have filed the following documents as part of this Annual Report:

Report of Independent Registered Public Accounting Firm .............................................................................

Balance Sheets .........................................................................................................................................

Statements of Operations ...........................................................................................................................

Statements of Stockholders’

Equity (Deficit) .................................................................................................

Statements of Cash Flows .........................................................................................................................

Notes to Financial Statements .....................................................................................................................

We have filed the following documents as part of this Annual Report on Form 10-K/A:

Consolidated Balance Sheets (As Restated)

Consolidated Statements of Income (Loss) (As Restated)

Consolidated Statements of Comprehensive Income (Loss) (As Restated)

Consolidated Statements of Stockholders’ Equity (As Restated)

Consolidated Statements of Cash Flows (As Restated)

Notes to Consolidated Financial Statements (As Restated)

Financial Statement Schedules.

All schedules have been omitted because they are not applicable or required, or the information required to be set forth therein is included in the Financial Statements or notes thereto included in Item 8 of this Annual Report on Form 10 ‑K.

Amended and Restated Certificate of Incorporation of the Company (incorporated by reference to Exhibit 3.1 to the Company’s Current Report on Form 8 ‑K, filed with the SEC on December 11, 2013).

Amended and Restated Bylaws of the Company (incorporated by reference to Exhibit 3.2 to the Company’s Current Report on Form 8 ‑K, filed with the SEC on December 11, 2013).

Form of Common Stock Certificate of the Company (incorporated by reference to Exhibit 4.1 to the Company’s Registration Statement on Form S ‑1, as amended (File No.

333 ‑191689), originally filed with the SEC on October 25, 2013).

Third Amended and Restated Investor Rights Agreement, dated June 26, 2013, among the Company and certain of its stockholders incorporated by reference to Exhibit 4.2 to the Company’s Registration Statement on Form S ‑1, as amended (File No.

Number Description

3.1 Amended and Restated Certificate of Incorporation of the Company (incorporated by reference to Exhibit 3.1 to the Company’s Current Report on Form 8-K, filed with the SEC on December 11, 2013).

3.2 Second Amended and Restated Bylaws of the Company (incorporated by reference to Exhibit 3.2 to the Company's 10-K filed with the SEC on February 27, 2023).

4.1 Form of Common Stock Certificate of the Company (incorporated by reference to Exhibit 4.1 to the Company’s Registration Statement on Form S-1, as amended (File No.

333-191689), originally filed with the SEC on October 25, 2013).

Form of Indemnity Agreement between the Company and its directors and officers (incorporated by reference to Exhibit 10.1 to the Company’s Registration Statement on Form S ‑1, as amended (File No.

4.2* Third Amended and Restated Investor Rights Agreement, dated June 26, 2013, among the Company and certain of its stockholders incorporated by reference to Exhibit 4.2 to the Company’s Registration Statement on Form S-1, as amended (File No.

333-191689), originally filed with the SEC on October 11, 2013).

2010 Equity Incentive Plan, as amended, and Form of Stock Option Grant Notice, Option Agreement and Form of Notice of Exercise (incorporated by reference to Exhibit 10.2 to the Company’s Registration Statement on Form S ‑1, as amended (File No.

4.3 Description of the Common Stock of the Company (incorporated by reference to Exhibit 4.3 to the Company’s Form 10-K filed with the SEC on February 25, 2020).

10.1* Form of Indemnity Agreement between the Company and its directors and officers (incorporated by reference to Exhibit 10.1 to the Company’s Registration Statement on Form S-1, as amended (File No.

333-191689), originally filed with the SEC on October 11, 2013).

2013 Equity Incentive Plan and Form of Stock Option Agreement and Form of Stock Option Grant Notice thereunder (incorporated by reference to Exhibit 10.3 to the Company’s Registration Statement on Form S ‑ 1, as amended (File No.

10.2* Xencor, Inc.

333-191689), originally filed with the SEC on October 11, 2013).

2013 Employee Stock Purchase Plan (incorporated by reference to Exhibit 10.4 to the Company’s Registration Statement on Form S ‑1, as amended (File No.

10.3* Xencor, Inc.

333-191689), originally filed with the SEC on October 11, 2013).

Non ‑Employee Director Compensation Policy (incorporated by reference to Exhibit 10.5 to the Company’s Registration Statement on Form S ‑1, as amended (File No.

10.4* Xencor, Inc.

2013 Employee Stock Purchase Plan (incorporated by reference to Exhibit 10.4 to the Company’s Registration Statement on Form S-1, as amended (File No.

333-191689), originally filed with the SEC on October 11, 2013).

10.5* Second Amended and Restated Executive Employment Agreement, dated January 1, 2007, by and between the Company and Dr.

Dahiyat (incorporated by reference to Exhibit 10.6 to the Company’s Registration Statement on Form S ‑1, as amended (File No.

333 ‑191689), originally filed with the SEC on October 11, 2013).

Offer Letter, dated January 12, 2010, by and between the Company and Dr.

Edgardo Baracchini, Jr.

(incorporated by reference to Exhibit 10.7 to the Company’s Registration Statement on Form S ‑1, as amended (File No.

333 ‑191689), originally filed with the SEC on October 11, 2013).

Offer Letter, dated September 28, 2009, by and between the Company and Dr.

Bruce Carter (incorporated by reference to Exhibit 10.8 to the Company’s Registration Statement on Form S ‑1, as amended (File No.

333 ‑ 191689), originally filed with the SEC on October 11, 2013).

Amendment to Offer Letter, dated November 18, 2010, by and between the Company and Dr.

Bruce Carter (incorporated by reference to Exhibit 10.9 to the Company’s Registration Statement on Form S ‑1, as amended (File No.

333 ‑191689), originally filed with the SEC on October 11, 2013).

Amended Consulting Agreement, dated January 1, 2011, by and between the Company and Development and Strategic Consulting Associates, LLC (incorporated by reference to Exhibit 10.10 to the Company’s Registration Statement on Form S ‑1, as amended (File No.

333 ‑191689), originally filed with the SEC on October 11, 2013).

Offer Letter, dated August 1, 2012, by and between the Company and Dr.

Paul Foster (incorporated by reference to Exhibit 10.11 to the Company’s Registration Statement on Form S ‑1, as amended (File No.

Dahiyat (incorporated by reference to Exhibit 10.6 to the Company’s Registration Statement on Form S-1, as amended (File No.

333-191689), originally filed with the SEC on October 11, 2013).

10.6* Amended and Restated Executive Employment Agreement, dated September 4, 2013, by and between the Company and Dr.

Dahiyat (incorporated by reference to Exhibit 10.12 to the Company’s Registration Statement on Form S ‑1, as amended (File No.

333 ‑191689), originally filed with the SEC on October 11, 2013).

Offer Letter, dated September 5, 2013, by and between the Company and Dr.

Edgardo Baracchini, Jr.

(incorporated by reference to Exhibit 10.13 to the Company’s Registration Statement on Form S ‑1, as amended (File No.

Dahiyat (incorporated by reference to Exhibit 10.12 to the Company’s Registration Statement on Form S-1, as amended (File No.

333-191689), originally filed with the SEC on October 11, 2013).

10.7* Amended and Restated Severance Agreement, dated September 5, 2013, by and between the Company and Dr.

Desjarlais (incorporated by reference to Exhibit 10.14 to the Company’s Registration Statement on Form S ‑1, as amended (File No.

Desjarlais (incorporated by reference to Exhibit 10.14 to the Company’s Registration Statement on Form S-1, as amended (File No.

333-191689), originally filed with the SEC on October 11, 2013).

10.8* Amended and Restated Change in Control Agreement, dated September 5, 2013, by and between the Company and John J.

Kuch (incorporated by reference to Exhibit 10.15 to the Company’s Registration Statement on Form S ‑1, as amended (File No.

333 ‑191689), originally filed with the SEC on October 11, 2013).

Offer Letter, dated August 12, 2013, by and between the Company and Dr.

Paul Foster (incorporated by reference to Exhibit 10.16 to the Company’s Registration Statement on Form S ‑1, as amended (File No.

333 ‑191689), originally filed with the SEC on October 11, 2013).

10.17†

‑Derived Cell Line Sale Agreement, dated December 21, 2011, by and between the Company and Catalent Pharma Solutions, LLC (incorporated by reference to Exhibit 10.17 to the Company’s Registration Statement on Form S ‑1, as amended (File No.

333 ‑191689), originally filed with the SEC on October 11, 2013).

10.18†

Development and Manufacturing Services Agreement, dated September 15, 2005, by and between the Company and Catalent Pharma Solutions (formerly Cardinal Health PTS, LLC) (incorporated by reference to Exhibit 10.18 to the Company’s Registration Statement on Form S ‑1, as amended (File No.

333 ‑191689), originally filed with the SEC on October 11, 2013).

10.19†

Collaboration and License Agreement, dated June 27, 2010, by and between the Company and MorphoSys AG (incorporated by reference to Exhibit 10.19 to the Company’s Registration Statement on Form S ‑1, as amended (File No.

333 ‑191689), originally filed with the SEC on October 11, 2013).

10.20†

First Amendment to the Collaboration and License Agreement, dated March 23, 2012, by and between the Company and MorphoSys AG (incorporated by reference to Exhibit 10.20 to the Company’s Registration Statement on Form S ‑ 1, as amended (File No.

333 ‑191689), originally filed with the SEC on October 11, 2013).

10.21†

Option and License Agreement, dated January 28, 2013, by and between the Company and Alexion Pharmaceuticals, Inc.

(incorporated by reference to Exhibit 10.23 to the Company’s Registration Statement on Form S ‑1, as amended (File No.

Kuch (incorporated by reference to Exhibit 10.15 to the Company’s Registration Statement on Form S-1, as amended (File No.

333-191689), originally filed with the SEC on October 11, 2013).

10.22†

Collaboration Agreement, dated February 10, 2012, by and between the Company and Boehringer Ingelheim International GmbH (incorporated by reference to Exhibit 10.24 to the Company’s Registration Statement on Form S ‑1, as amended (File No.

10.9† Collaboration and License Agreement, dated June 27, 2010, by and between the Company and MorphoSys AG (incorporated by reference to Exhibit 10.19 to the Company’s Registration Statement on Form S-1, as amended (File No.

333-191689), originally filed with the SEC on October 11, 2013).

10.23†

Cross ‑License Agreement, dated December 19, 2012, by and between the Company and MedImmune, LLC (incorporated by reference to Exhibit 10.26 to the Company’s Registration Statement on Form S ‑1, as amended (File No.

10.10† First Amendment to the Collaboration and License Agreement, dated March 23, 2012, by and between the Company and MorphoSys AG (incorporated by reference to Exhibit 10.20 to the Company’s Registration Statement on Form S-1, as amended (File No.

333-191689), originally filed with the SEC on October 11, 2013).

Employment Agreement dated August 29, 2014 by and between the Company and Lloyd Rowland (incorporated by reference to Exhibit 10.1 to the Company’s Form 10-Q filed with the SEC on November 10, 2014).

Lease dated January 1, 2015 by and between the Company and BF Monrovia, LLC (incorporated by reference to Exhibit 99.1 to the Company’s Form 8-K filed with the SEC on January 5, 2015).

Master Service Agreement dated July 14, 2014 by and between the Company and KBI Biopharma, Inc.

(incorporated by reference to Exhibit 10.26 to the Company’s Form 10-K filed with the SEC on February 20, 2015).

10.11 Lease dated January 1, 2015 by and between the Company and BF Monrovia, LLC (incorporated by reference to Exhibit 99.1 to the Company’s Form 8-K filed with the SEC on January 5, 2015).

10.12 Amendment to Lease dated January 27, 2015 by and between the Company and BF Monrovia, LLC.

(incorporated by reference to Exhibit 10.27 to the Company’s Form 10-K filed with the SEC on February 20, 2015).

Subsidiaries of the Company (incorporated by reference to Exhibit 10.26 to the Company’s Registration Statement on Form S ‑1, as amended (File No.

(incorporated by reference to Exhibit 10.27 to the Company’s Form 10-K filed with the SEC on February 20, 2015).

10.13† Research and License Agreement effective September 15, 2015 between the Company and Amgen Inc., (incorporated by reference to Exhibit 10.1 to the Company’s Form 10-Q filed with the SEC on November 4, 2015).

10.14* Severance Agreement, dated May 26, 2016 by and between the Company and Bassil Dahiyat (incorporated by reference to Exhibit 10.1 to the Company's Form 10-Q filed with the SEC on August 3, 2016).

10.15* Severance Agreement, dated May 26, 2016 by and between the Company and John Kuch (incorporated by reference to Exhibit 10.2 to the Company's Form 10-Q filed with the SEC on August 3, 2016).

10.16* Severance Agreement, dated May 26, 2016 by and between the Company and John Desjarlais (incorporated by reference to Exhibit 10.3 to the Company's Form 10-Q filed with the SEC on August 3, 2016).

10.17† Collaboration and License Agreement, dated June 26, 2016, by and between the Company and Novartis Institutes for BioMedical Research, Inc.

(incorporated by reference to Exhibit 10.6 to the Company's Form 10-Q filed with the SEC on August 3, 2016).

10.18† Amendment No.

1, dated September 21, 2016, to the Collaboration and License Agreement by and between the Company and Novartis Institutes for BioMedical Research, Inc.

(incorporated by reference to Exhibit 10.2 to the Company's Form 10-Q filed with the SEC on November 2, 2016).

10.19 Office Lease, dated June 21, 2017, by and among the Company and PRII High Bluffs LLC and Collins Corporate Center Partners, LLC (incorporated by reference to Exhibit 99.1 to the Company’s Form 8-K filed with the SEC on June 26, 2017).

10.20 Second Amendment to Lease, dated July 5, 2017, by and between the Company and 111 Lemon Investors LLC (incorporated by reference to Exhibit 99.1 to the Company’s Form 8-K filed with the SEC on July 10, 2017).

10.21† Collaboration and License Agreement, dated February 4, 2019, by and between the Company and Genentech, Inc.

Hoffman-La Roche LTD (incorporated by reference to Exhibit 10.1 to the Company’s Form 10-Q filed with the SEC on May 9, 2019).

10.22* Employment Agreement dated August 5, 2019 by and between the Company and Celia Eckert (incorporated by reference to Exhibit 10.33 to the Company’s Form 10-K filed with the SEC on February 25, 2020).

10.23 Third Amendment to Lease, dated April 30, 2020, by and between the Company and 111 Lemon Investors LLC (incorporated by reference to Exhibit 10.1 to the Company’s Form 10-Q filed with the SEC on August 5, 2020).

10.24 Fourth Amendment to Lease, dated September 30, 2020, by and between the Company and 111 Lemon Investors LLC (incorporated by reference to Exhibit 10.2 to the Company’s Form 10-Q filed with the SEC on November 6, 2020).

10.25 First Amendment to the Research and License Agreement, dated November 22, 2019, by and between the Company and Amgen Inc.

(incorporated by reference to Exhibit 10.29 to the Company’s Form 10-K filed with the SEC on February 23, 2021).

10.26 Second Amendment to the License Agreement, dated January 8, 2020, by and between the Company and MorphoSys AG (incorporated by reference to Exhibit 10.31 to the Company’s Form 10-K filed with the SEC on February 23, 2021).

10.27 Third Amendment to the License Agreement, dated July 13, 2020, by and between the Company and MorphoSys AG (incorporated by reference to Exhibit 10.32 to the Company’s Form 10-K filed with the SEC on February 23, 2021).

10.28 Fifth Amendment to Lease, dated October 31, 2020, by and between the Company and 111 Lemon Investors LLC (incorporated by reference to Exhibit 10.33 to the Company’s Form 10-K filed with the SEC on February 23, 2021).

10.29 Collaboration and License Agreement, dated December 4, 2020, by and between the Company and Janssen Biotech, Inc.

(incorporated by reference to Exhibit 10.34 to the Company’s Form 10-K filed with the SEC on February 23, 2021).

10.30 First Amendment to the Collaboration and License Agreement, dated March 10, 2021, by and between the Company and Genentech, Inc.

Hoffmann-La Roche LTD (incorporated by reference to Exhibit 10.1 to the Company’s Form 10-Q filed with the SEC on May 5, 2021).

Form of Restricted Stock Unit Agreement (incorporated by reference to Exhibit 10.1 to the Company’s Current Report on Form 8-K, filed with the SEC on March 10, 2021).

10.32 Second Amendment to the Collaboration and License Agreement, dated June 30, 2021, by and between the Company and Genentech, Inc., and F.

Hoffmann-La Roche LTD (incorporated by reference to Exhibit 10.1 to the Company’s Form 10-Q filed with the SEC on August 4, 2021).

10.33 Agreement of Lease, dated April 30, 2021, by and between the Company and Angelo Gordon Real Estate, Inc.

(incorporated by reference to Exhibit 10.2 to the Company’s Form 10-Q filed with the SEC on August 4, 2021).

10.34 First Amendment to Lease, dated July 13, 2021, by and between the Company and Angelo Gordon Real Estate, Inc.

(incorporated by reference to Exhibit 10.3 to the Company’s Form 10-Q filed with the SEC on August 4, 2021).

Collaboration and License Agreement, dated October 1, 2021, by and between the Company and Janssen Biotech, Inc.

(incorporated by reference to Exhibit 10.39 to the Company's Form 10-K filed with the SEC on February 24, 2022).

10.36 First Amendment to Office Lease, dated May 19, 2022, by and between the Company and PRII High Bluffs LLC and Collins Corporate Center Partners, LLC (incorporated by reference to Exhibit 10.1 to the Company's Form 10-Q filed with the SEC on August 3, 2022).

10.37 Second Amendment to Lease, dated August 2, 2022, by and between the Company and AG-LC 465 North Halstead Owner, L.P.

(incorporated by reference to Exhibit 10.1 to the Company's Form 10-Q filed with the SEC on November 7, 2022).

10.38 Sixth Amendment to Lease, dated November 14, 2022, by and between the Company and 111 Lemon Investors LLC (incorporated by reference to Exhibit 10.39 to the Company's Form 10-K filed with the SEC on February 27, 2023).

10.39 Xencor, Inc.

Amended and Restated Non-Employee Director Compensation Policy (incorporated by reference to Exhibit 10.40 to the Company's Form 10-K filed with the SEC on February 27, 2023).

10.40 Option and License Agreement, dated January 28, 2013, by and between the Company and Alexion Pharmaceuticals, Inc.

(incorporated by reference to Exhibit 10.23 to the Company’s Registration Statement on Form S 1, as amended (File No.

333 191689), originally filed with the SEC on October 11, 2013).

Consent of Independent Registered Public Accounting Firm.

Power of Attorney.

Reference is made to the signature page hereto (incorporated by reference to Exhibit 24.1 to the Company’s Form 10-K filed with the SEC on February 20, 2015).

First Amendment to Option and License Agreement dated June14, 2019 by and between the Company and Alexion Pharma Holding (as successor to Alexion Pharmaceuticals, Inc.) (incorporated by reference to Exhibit 10.42 to the Company's Form 10-K filed with the SEC on February 27, 2023).

Second Amendment to Option and License Agreement dated November 28, 2022 by and between the Company and Alexion Pharma International Operations Limited (as successor to Alexion Pharmaceuticals, Inc.) (incorporated by reference to Exhibit 10.43 to the Company's Form 10-K filed with the SEC on February 27, 2023).

10.43 Sales Agreement dated February 27, 2023 by and between the Registrant and SVB Securities LLC (incorporated by reference in Exhibit 1.2 to the Company's Form S-3ASR filed with the SEC on February 27, 2023).

2023 Equity Incentive Plan (incorporated herein by reference to Exhibit 99.1 to the Registrant’s Definitive Proxy Statement on Schedule 14A for the 2023 Annual Meeting of Stockholders of the Registrant, filed with the SEC on April 26, 2023).

10.45 First Amendment to Collaboration and License Agreement, dated January 30, 2023, by and between the Company and Janssen Biotech, Inc.

(incorporated by reference in Exhibit 10.1 to the Company's Form 10-Q filed with the SEC on August 3, 2023).

Executive Employment Agreement Addendum dated November 7, 2023 by and between the Company and Celia Eckert (incorporated by reference in Exhibit 10.1 to the Company's Form 10-Q filed with the SEC on November 8, 2023).

Executive Employment Agreement Addendum dated November 7, 2023 by and between the Company and Nancy Valente (incorporated by reference in Exhibit 10.2 to the Company's Form 10-Q filed with the SEC on November 8, 2023).

10.48 Amended and Restated Collaboration and License Agreement, executed on November 14, 2023 and effective as of June 1, 2024, by and between the Company and Genentech, Inc.

Hoffmann-La Roche Ltd.

(incorporated by reference in Exhibit 10.48 to the Company's Form 10-K filed with the SEC on February 29, 2024).

23.1# Consent of Independent Registered Public Accounting Firm (RSM US LLP).

31.1 Certification of the Principal Executive Officer pursuant to Rule 13a-14(a) or 15d-14(a) of the Securities Exchange Act of 1934 .

4 unchanged sentences

Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002 .

XBRL Taxonomy Extension Schema Document.

XBRL Taxonomy Extension Definition Linkbase Document.

XBRL Taxonomy Extension Label Linkbase Document.

XBRL Taxonomy Extension Presentation Linkbase Document.

XBRL Taxonomy Extension Schema Document.

97 Xencor, Inc.

Compensation Recovery Policy (incorporated by reference in Exhibit 97 to the Company's Form 10-K filed with the SEC on February 29, 2024).

101.INS XBRL Instance Document – The instance document does not appear in the Interactive Data File because its XBRL tags are embedded within the inline XBRL document.

101.SCH XBRL Taxonomy Extension Schema Document.

101.CAL XBRL Taxonomy Extension Schema Document.

101.DEF XBRL Taxonomy Extension Definition Linkbase Document.

101.LAB XBRL Taxonomy Extension Label Linkbase Document.

101.PRE XBRL Taxonomy Extension Presentation Linkbase Document.

104 104 Cover Page Interactive Data File (formatted as Inline XBRL and contained in Exhibit 101)

______________________________

# Filed herewith

† We have received confidential treatment for certain portions of this agreement, which have been omitted and filed separately with the SEC pursuant to Rule 406 under the Securities Act of 1933, as amended.

1 unchanged sentence

** These certifications are being furnished solely to accompany this annual report pursuant to 18 U.S.C.

Section 1350, and are not being filed for purposes of Section 18 of the Securities Exchange Act of 1934 and are not to be incorporated by reference into any filing of the Company, whether made before or after the date hereof, regardless of any general incorporation language in such filing.

Section 1350, and are not being filed for purposes of Section 18 of the Securities Exchange Act of 1934 and are not to be

incorporated by reference into any filing of the Company, whether made before or after the date hereof, regardless of any general incorporation language in such filing.

Pursuant to the requirements of Section 13 or 15(d) of the Securities Exchange Act of 1934, the Company has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

February 23, 2025

/s/ Bassil I.

Dahiyat, Ph.D.

/s/ B ASSIL I.

D AHIYAT , P H .D.

Dahiyat, Ph.D.

1 unchanged sentence

POWER OF ATTORNEY

Pursuant to the requirements of the Securities Exchange Act of 1934, this report has been signed below by the following persons on behalf of the Company and in the capacities and on the dates indicated.

/s/ Bassil I.

Dahiyat, Ph.D.

Director, President & Chief Executive Officer (Principal Executive Officer)

February 23, 2015

Dahiyat, Ph.D.

Vice President, Finance (Principal Financial and Accounting Officer)

February 23, 2015

/s/ Bruce L.A.

Carter, Ph.D.

Chairman of the Board of Directors

February 23, 2015

Carter, Ph.D.

/s/ Robert F.

Baltera, Jr.*

February 23, 2015

/s/ Jonathan Fleming *

February 23, 2015

Jonathan Fleming

Stafford III*

February 23, 2015

* Pursuant to Power of Attorney

/s/ Bassil I.

KNOW ALL MEN BY THESE PRESENTS, that each person whose signature appears below constitutes and appoints Bassil I.

Dahiyat, Ph.D.

and Bart Jan Cornelissen, and each of them, his true and lawful attorneys-in-fact, each with full power of substitution, for him in any and all capacities, to sign any amendments to this Annual Report on Form 10-K/A and to file the same, with exhibits thereto and other documents in connection therewith, with the Securities and Exchange Commission, hereby ratifying and confirming all that each of said attorneys-in-fact or their substitute or substitutes may do or cause to be done by virtue hereof.

Signature Title Date

/s/ B ASSIL I.

D AHIYAT , P H .D.

Director, President & Chief Executive Officer (Principal Executive Officer) February 23, 2025

Dahiyat, Ph.D.

Attorney-in-Fact

EXHIBIT INDEX