−Removed: MANAGEMENT’S DISCUSSION AND ANALYSIS
−Removed: OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS
−Removed: The following
−Removed: discussion and analysis of our financial condition and results of operations for the three months ended March 31, 2022 and 2021 should
−Removed: be read in conjunction with our condensed consolidated financial statements and related notes to those condensed consolidated financial
−Removed: statements that are included elsewhere in this report.
−Removed: Our discussion includes forward-looking statements based upon current expectations
−Removed: that involve risks and uncertainties, such as our plans, objectives, expectations and intentions.
−Removed: Actual results and the timing of events
−Removed: could differ materially from those anticipated in these forward-looking statements as a result of a number of factors, including those
−Removed: set forth under the Risk Factors, Special Note Regarding Forward-Looking Statements and Business sections in our Form 10-K as filed with
−Removed: the Securities and Exchange Commission on March 30, 2022.
−Removed: We use words such as “anticipate,” “estimate,” “plan,”
−Removed: “project,” “continuing,” “ongoing,” “expect,” “believe,” “intend,”
−Removed: “may,” “will,” “should,” “could,” and similar expressions to identify forward-looking
+Added: MANAGEMENT’S DISCUSSION AND
+Added: ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS
+Added: The following discussion and analysis of our
+Added: financial condition and results of operations for the three and six months ended June 30, 2022 and 2021 should be read in conjunction
+Added: with our condensed consolidated financial statements and related notes to those condensed consolidated financial statements that are
+Added: included elsewhere in this report.
+Added: Our discussion includes forward-looking statements based upon current expectations that involve risks
+Added: and uncertainties, such as our plans, objectives, expectations and intentions.
+Added: Actual results and the timing of events could differ materially
+Added: from those anticipated in these forward-looking statements as a result of a number of factors, including those set forth under the Risk
+Added: Factors, Special Note Regarding Forward-Looking Statements and Business sections in our Form 10-K as filed with the Securities and Exchange
+Added: Commission on March 30, 2022.
+Added: We use words such as “anticipate,” “estimate,” “plan,” “project,”
+Added: “continuing,” “ongoing,” “expect,” “believe,” “intend,” “may,”
+Added: “will,” “should,” “could,” and similar expressions to identify forward-looking statements.
Impact of COVID-19
1 unchanged sentence
Although the COVID-19
−Removed: vaccines have generally been introduced to the public, the ultimate impact of the COVID-19 pandemic on our operations is unknown and will
−Removed: depend on future developments, which are highly uncertain and cannot be predicted with confidence, including the duration of the COVID-19
−Removed: outbreak, new information which may emerge concerning the severity of the COVID-19 pandemic, a significant increase in new and variant
−Removed: strains of COVID-19 cases, availability and effectiveness of COVID-19 vaccines and therapeutics, the level of acceptance of the vaccine
−Removed: by the general population and any additional preventative and protective actions that governments, or us, may determine are needed.
+Added: vaccines have generally been introduced to the public, the ultimate impact of the COVID-19 pandemic on our operations is unknown and
+Added: will depend on future developments, which are highly uncertain and cannot be predicted with confidence, including the duration of the
+Added: COVID-19 outbreak, new information which may emerge concerning the severity of the COVID-19 pandemic, a significant increase in new and
+Added: variant strains of COVID-19 cases, availability and effectiveness of COVID-19 vaccines and therapeutics, the level of acceptance of the
+Added: vaccine by the general population and any additional preventative and protective actions that governments, or us, may determine are needed.
The occurrence of COVID-19
pandemic had negative impact on our operations.
−Removed: Some of the universities and laboratories with which we collaborate were temporarily closed.
+Added: Some of the universities and laboratories with which we collaborate were temporarily
Our general development operations have continued during the COVID-19 pandemic and we have not had significant disruption.
−Removed: are uncertain if the COVID-19 pandemic will impact future operations at our laboratory, or our ability to collaborate with other laboratories
+Added: we are uncertain if the COVID-19 pandemic will impact future operations at our laboratory, or our ability to collaborate with other laboratories
and universities.
5 unchanged sentences
available to fund planned operations and although we have other sources of capital described below under “Liquidity and Capital
−Removed: Resources,” management continues to pursue various financing alternatives to fund our operations so we can continue as a going concern.
+Added: Resources,” management continues to pursue various financing alternatives to fund our operations so we can continue as a going
However, the COVID-19 pandemic has created significant economic uncertainty and volatility in the credit and capital markets.
−Removed: plans to secure the necessary financing through the issue of new equity and/or the entering into of strategic partnership arrangements
−Removed: but the ultimate impact of the COVID-19 pandemic on our ability to raise additional capital is unknown and will depend on future developments,
−Removed: which are highly uncertain and cannot be predicted with confidence, including the duration of the COVID-19 outbreak and new information
−Removed: which may emerge concerning the severity of the COVID-19 pandemic.
−Removed: We may not be able to raise sufficient additional capital and may tailor
−Removed: our operations based on the amount of funding we are able to raise in the future.
−Removed: Nevertheless, there is no assurance that these initiatives
−Removed: will be successful.
−Removed: Further, there is no assurance that capital available to us in any future financing will be on acceptable terms.
+Added: Management plans to secure the necessary financing through the issue of new equity and/or the entering into of strategic partnership
+Added: arrangements but the ultimate impact of the COVID-19 pandemic on our ability to raise additional capital is unknown and will depend on
+Added: future developments, which are highly uncertain and cannot be predicted with confidence, including the duration of the COVID-19 outbreak
+Added: and new information which may emerge concerning the severity of the COVID-19 pandemic.
+Added: We may not be able to raise sufficient additional
+Added: capital and may tailor our operations based on the amount of funding we are able to raise in the future.
+Added: Nevertheless, there is no assurance
+Added: that these initiatives will be successful.
+Added: Further, there is no assurance that capital available to us in any future financing will be
+Added: on acceptable terms.
is a clinical-stage, vertically integrated, leading CellTech bio-developer dedicated to advancing and empowering innovative, transformative
−Removed: immune effector cell therapy, exosome technology, as well as COVID-19 related diagnostics and therapeutics.
−Removed: The Company also provides
−Removed: strategic advisory and outsourcing services to facilitate and enhance its clients’ growth and development, as well as competitiveness
−Removed: in healthcare and CellTech industry markets.
−Removed: Through its subsidiary structure with unique integration of verticals from innovative R&D
−Removed: to automated bioproduction and accelerated clinical development, the Company is establishing a leading role in the fields of cellular
−Removed: immunotherapy (including CAR-T/NK), exosome technology (ACTEX™), and COVID-19 related vaccine and therapeutics.
−Removed: Avalon achieves and fosters
−Removed: seamless integration of unique verticals to bridge and accelerate innovative research, bio-process development, clinical programs and
−Removed: product commercialization.
+Added: immune effector cell therapy, exosome technology, as well as companion diagnostics.
+Added: The Company also provides strategic advisory and outsourcing
+Added: services to facilitate and enhance its clients’ growth and development, as well as competitiveness in healthcare and CellTech industry
+Added: Through its subsidiary structure with unique integration of vertical segments from innovative R&D to automated bioproduction
+Added: and accelerated clinical development, the Company is establishing a leading role in the fields of cellular immunotherapy (including CAR-T/NK),
+Added: exosome technology (ACTEX™), and regenerative therapeutics.
+Added: Avalon achieves
+Added: and fosters seamless integration of unique verticals to bridge and accelerate innovative research, bio-process development, clinical programs
+Added: and product commercialization.
Avalon’s upstream innovative research includes:
Development of Avalon Clinical-grade Tissue-specific Exosome (“ACTEX™”)
−Removed: ● Novel therapeutic and diagnostic targets development utilizing QTY-code protein design technology with
−Removed: Massachusetts Institute of Technology (MIT) including using the QTY code protein design technology for development of a hemofiltration
−Removed: device to treat Cytokine Storm.
−Removed: ● Co-development of next generation, transposon-based, multi-target CAR-T, CAR-NK and other immune effector
−Removed: cell therapeutic modalities with Arbele Limited.
−Removed: ● Strategic partnership with the University of Natural Resources and Life Sciences (BOKU) in Vienna, Austria
−Removed: to develop an S-layer vaccine that can be administered by an intranasal or oral route against SARS-CoV-2, the novel coronavirus that causes
−Removed: COVID-19 disease.
−Removed: Avalon’s midstream
−Removed: bio-processing and bio-production facility is located in Nanjing, China with state-of-the-art, automated GMP and QC/QA infrastructure
−Removed: for standardized bio-manufacturing of clinical-grade cellular products involved in our clinical programs in immune effector cell therapy,
−Removed: regenerative therapeutics, as well as bio-banking.
−Removed: Avalon’s downstream
−Removed: medical team and facility consists of top-rated affiliated hospital network and experts specialized in hematology, oncology, cellular
−Removed: immunotherapy, hematopoietic stem/progenitor cell transplant, as well as regenerative therapeutics.
−Removed: Our major clinical programs include:
−Removed: Avalon has initiated its first-in-human clinical trial of CD19 CAR-T candidate, AVA-001 in August
−Removed: 2019 at the Hebei Yanda Lu Daopei Hospital and Beijing Lu Daopei Hospital in China (the world’s single largest CAR-T treatment network
−Removed: with over 600 patients being treated with CAR-T) for the indication of relapsed/refractory B-cell acute lymphoblastic leukemia and non-Hodgkin
+Added: Novel therapeutic and diagnostic targets development utilizing QTY-code protein design technology with Massachusetts Institute of Technology (MIT) including using the QTY code protein design technology for development of a hemofiltration device to treat Cytokine Storm.
+Added: Co-development of next generation, mRNA-based immune effector cell therapeutic modalities with Arbele Limited.
+Added: midstream bio-processing and bio-production facility is co-developed at the University of Pittsburgh Medical Center (UPMC) with state-of-the-art
+Added: infrastructure and standardization accredited with cGMP, FACT, aaBB, CLIA and CAP, as well as stringent QC/QA facility for standardized
+Added: bio-manufacturing of clinical-grade cellular products involved in our clinical programs in immune effector cell therapy and ACTEX-based
+Added: regenerative therapeutics.
+Added: downstream medical team and facility consists of top-rated affiliated hospital network and experts specialized in hematology, oncology,
+Added: cellular immunotherapy, hematopoietic stem/progenitor cell transplant, as well as regenerative therapeutics.
+Added: Our major clinical programs
+Added: Avalon has initiated its first-in-human clinical trial of CD19 CAR-T candidate, AVA-001 in August 2019 at the Hebei Yanda Lu Daopei Hospital and Beijing Lu Daopei Hospital in China (the world’s single largest CAR-T treatment network with over 1,200 patients being treated with CAR-T) for the indication of relapsed/refractory B-cell acute lymphoblastic leukemia and non-Hodgkin Lymphoma).
The AVA-001 candidate (co-developed with China Immunotech Co.
−Removed: Ltd) is characterized by the utilization of 4-1BB (CD137) co-stimulatory
−Removed: signaling pathway, conferring a strong anti-cancer activity during pre-clinical study.
−Removed: It also features a shorter bio-manufacturing time
−Removed: which leads to the advantage of prompt treatment to patients where timing is important related hematologic malignancies.
−Removed: Avalon has successfully
−Removed: completed the first-in-human clinical trial of its AVA-001 anti-CD19 CAR-T cell therapy as a bridge to allogeneic bone marrow transplantation
−Removed: for patients with relapsed/refractory B-cell acute lymphoblastic leukemia at the Lu Daopei Hospital (registered clinical trial number
−Removed: NCT03952923) with excellent efficacy (90% complete remission rate) and minimal adverse side effects.
−Removed: Avalon is currently expanding
−Removed: the patient recruitment for AVA-001 to include relapsed/refractory non-Hodgkin lymphoma patients.
+Added: Ltd) is characterized by the utilization of 4-1BB (CD137) co-stimulatory signaling pathway, conferring a strong anti-cancer activity during pre-clinical study.
+Added: It also features a shorter bio-manufacturing time which leads to the advantage of prompt treatment to patients where timing is important related hematologic malignancies.
+Added: Avalon has successfully completed the first-in-human clinical trial of its AVA-001 anti-CD19 CAR-T cell therapy as a bridge to allogeneic bone marrow transplantation for patients with relapsed/refractory B-cell acute lymphoblastic leukemia at the Lu Daopei Hospital (registered clinical trial number NCT03952923) with excellent efficacy (90% complete remission rate) and minimal adverse side effects.
+Added: Avalon is currently expanding the patient recruitment and indication for AVA-001 to include relapsed/refractory non-Hodgkin lymphoma patients.
AVA-011 and FLASH-CAR™:
−Removed: The Company advanced its next generation immune cell therapy using RNA-based,
−Removed: non-viral FLASH-CAR™ technology co-developed with the Company’s strategic partner Arbele Limited.
−Removed: The adaptable FLASH-CAR™
−Removed: platform can be used to create personalized cell therapy from a patient’s own cells, as well as off-the-shelf cell therapy from
−Removed: a universal donor.
−Removed: Our leading candidate, AVA-011, is currently at process development stage to generate clinical-grade cell-therapy products
−Removed: for subsequent clinical studies.
−Removed: On July 8, 2021, the Company and the University of Pittsburgh of the Commonwealth System of Higher
−Removed: Education (the “University”) entered into a Corporate Research Agreement (the “University Agreement”).
−Removed: to the University Agreement, for a term of two years the University agreed to use its reasonable efforts to perform academic research
−Removed: funded by the Company in connection with the development of point-of-care modular autonomous processing system to generate clinical-grade
−Removed: AVA-011, a RNA-based chimeric antigen receptor (CAR) T-cell therapy candidate (the “Project”) subject to the appointment of
−Removed: Yen Michael S.
−Removed: Hsu as Principal Investigator.
−Removed: During the term, the Company agreed to make eight payments of $125,000 to the
−Removed: As of March 31, 2022, the Company did not make any payment.
−Removed: The Company and the University shall each own an undivided, one
−Removed: half interest in any intellectual property rights jointly developed by both parties.
−Removed: The Company has been granted a worldwide, irrevocable,
−Removed: non-exclusive, royalty free, fully paid-up, perpetual right to use intellectual property developed by the University in connection with
−Removed: the Project for commercial purposes research activities and other purposes.
−Removed: Further, the Company will have an exclusive right of first
−Removed: offer to an exclusive royalty-bearing license to intellectual property developed by the University or co-developed by the Company and
−Removed: the University in connection with the Project.
−Removed: Stem cell-derived Avalon Clinical-grade Tissue-specific Exosomes (ACTEX™) is one of
−Removed: the core technology platforms that has been co-developed by Avalon GloboCare and the University of Pittsburgh Medical Center.
−Removed: formed a strategic partnership with HydroPeptide, LLC, a leading epigenetics skin care company, to engage in co-development and commercialization
−Removed: of a series of clinical-grade, exosome-based cosmeceutical and orthopedic products.
−Removed: As part of this agreement, the Company signed a three-way
−Removed: Material Transfer Agreement between Avalon GloboCare, HydroPeptide and the University of Pittsburgh Medical Center.
−Removed: Avalon’s AVA-Trap™ therapeutic program plans to enter animal model testing
−Removed: followed by expedited clinical studies with the goal of providing an effective therapeutic option to combat COVID-19 and other life-threatening
−Removed: conditions involving cytokine storms.
−Removed: The Company initiated a sponsored research and co-development project with Massachusetts Institute
−Removed: of Technology (MIT) led by Professor Shuguang Zhang as Principal Investigator in May 2019.
−Removed: Using the unique QTY code protein design platform,
−Removed: six water-soluble variant cytokine receptors have been successfully designed and tested to show binding affinity to the respective cytokines.
+Added: The Company advanced its next generation immune cell therapy using RNA-based, non-viral FLASH-CAR™ technology co-developed with the Company’s strategic partner Arbele Limited.
+Added: The multiplex FLASH-CAR™ platform can be used to create personalized ("autologous') cell therapy from a patient’s own cells, as well as "off-the-shelf" cell therapy from a universal donor.
+Added: Our leading candidate, AVA-011, is a dual-target (anti-CD19/CD22) CAR-T which has completed pre-clinical research stage, and currently at IND-enabling process development stage at UPMC (Dr.
+Added: Yen-Michael Hsu as Principal Investigator) to generate clinical-grade cell-therapy products for subsequent clinical studies.
+Added: Stem cell-derived Avalon Clinical-grade Tissue-specific Exosomes (ACTEX™) is one of the core technology platforms that has been co-developed by Avalon GloboCare and the University of Pittsburgh Medical Center.
+Added: The Company formed a strategic partnership with HydroPeptide, LLC, a leading epigenetics skin care company, to engage in co-development and commercialization of a series of clinical-grade, exosome-based cosmeceutical and orthopedic products.
+Added: As part of this agreement, the Company signed a three-way Material Transfer Agreement between Avalon GloboCare, HydroPeptide and the University of Pittsburgh Medical Center.
+Added: Avalon’s AVA-Trap™ therapeutic program plans to enter animal model testing followed by expedited clinical studies with the goal of providing an effective therapeutic option to combat COVID-19 and other life-threatening conditions involving cytokine storms.
+Added: The Company initiated a sponsored research and co-development project with Massachusetts Institute of Technology (MIT) led by Professor Shuguang Zhang as Principal Investigator in May 2019.
+Added: Using the unique QTY code protein design platform, six water-soluble variant cytokine receptors have been successfully designed and tested to show binding affinity to the respective cytokines.
Going Concern
−Removed: The Company is a clinical-stage,
−Removed: vertically integrated, leading CellTech bio-developer dedicated to advancing and empowering innovative, transformative immune effector
−Removed: cell therapy, exosome technology, as well as COVID-19 related diagnostics and therapeutics.
−Removed: The Company also provides strategic advisory
−Removed: and outsourcing services to facilitate and enhance its clients’ growth and development, as well as competitiveness in healthcare
−Removed: and CellTech industry markets.
−Removed: Through its subsidiary structure with unique integration of verticals from innovative R&D to automated
+Added: is a clinical-stage, vertically integrated, leading CellTech bio-developer dedicated to advancing and empowering innovative, transformative
+Added: immune effector cell therapy, exosome technology, as well as companion diagnostics.
+Added: The Company also provides strategic advisory and
+Added: outsourcing services to facilitate and enhance its clients’ growth and development, as well as competitiveness in healthcare and
+Added: CellTech industry markets.
+Added: Through its subsidiary structure with unique integration of vertical segments from innovative R&D to automated
bioproduction and accelerated clinical development, the Company is establishing a leading role in the fields of cellular immunotherapy
−Removed: (including CAR-T/NK), exosome technology (ACTEX™), and COVID-19 related vaccine and therapeutics.
+Added: (including CAR-T/NK), exosome technology (ACTEX™), and regenerative therapeutics.
In addition, the Company
2 unchanged sentences
These condensed
−Removed: consolidated financial statements have been prepared assuming that the Company will continue as a going concern, which contemplates, among
−Removed: other things, the realization of assets and the satisfaction of liabilities in the normal course of business.
−Removed: As reflected in the accompanying
−Removed: condensed consolidated financial statements, the Company had a working capital deficit of $4,234,370 as of March 31, 2022 and has incurred
−Removed: recurring net losses and generated negative cash flow from operating activities of $2,070,538 and $511,208 for the three months ended
−Removed: March 31, 2022, respectively.
−Removed: The Company has a limited operating history and its continued growth is dependent upon the continuation
−Removed: of providing medical related consulting services to its only few clients who are related parties and generating rental revenue from its
−Removed: income-producing real estate property in New Jersey;
−Removed: hence generating revenues, and obtaining additional financing to fund future obligations
−Removed: and pay liabilities arising from normal business operations.
−Removed: In addition, the current cash balance cannot be projected to cover the operating
−Removed: expenses for the next twelve months from the release date of this report.
−Removed: These matters raise substantial doubt about the Company’s
−Removed: ability to continue as a going concern.
−Removed: The ability of the Company to continue as a going concern is dependent on the Company’s
−Removed: ability to raise additional capital, implement its business plan, and generate significant revenues.
−Removed: There are no assurances that the
−Removed: Company will be successful in its efforts to generate significant revenues, maintain sufficient cash balance or report profitable operations
−Removed: or to continue as a going concern.
−Removed: The Company plans on raising capital through the sale of equity to implement its business plan.
−Removed: there is no assurance these plans will be realized and that any additional financings will be available to the Company on satisfactory
−Removed: terms and conditions, if any.
+Added: consolidated financial statements have been prepared assuming that the Company will continue as a going concern, which contemplates,
+Added: among other things, the realization of assets and the satisfaction of liabilities in the normal course of business.
+Added: As reflected in the
+Added: accompanying condensed consolidated financial statements, the Company had a working capital deficit of $5,557,470 as of June 30, 2022
+Added: and has incurred recurring net losses and generated negative cash flow from operating activities of $4,099,012 and $2,686,722 for the
+Added: six months ended June 30, 2022, respectively.
+Added: The Company has a limited operating history and its continued growth is dependent upon
+Added: the continuation of providing medical related consulting services to its only few clients who are related parties and generating rental
+Added: revenue from its income-producing real estate property in New Jersey;
+Added: hence generating revenues, and obtaining additional financing to
+Added: fund future obligations and pay liabilities arising from normal business operations.
+Added: In addition, the current cash balance cannot be
+Added: projected to cover the operating expenses for the next twelve months from the release date of this report.
+Added: These matters raise substantial
+Added: doubt about the Company’s ability to continue as a going concern.
+Added: The ability of the Company to continue as a going concern is
+Added: dependent on the Company’s ability to raise additional capital, implement its business plan, and generate significant revenues.
+Added: There are no assurances that the Company will be successful in its efforts to generate significant revenues, maintain sufficient cash
+Added: balance or report profitable operations or to continue as a going concern.
+Added: The Company plans on raising capital through the sale of equity
+Added: to implement its business plan.
+Added: However, there is no assurance these plans will be realized and that any additional financings will be
+Added: available to the Company on satisfactory terms and conditions, if any.
The occurrence of an
6 unchanged sentences
Given the dynamic nature of these circumstances, the duration
−Removed: of business disruption and reduced traffic, the related financial effect cannot be reasonably estimated at this time but is expected to
−Removed: adversely impact the Company’s business for the rest of 2022.
+Added: of business disruption and reduced traffic, the related financial effect cannot be reasonably estimated at this time but is expected
+Added: to adversely impact the Company’s business for the rest of 2022.
The accompanying condensed
1 unchanged sentence
or the amounts and classification of liabilities that may result should the Company be unable to continue as a going concern.
−Removed: Accounting Policies
+Added: Critical Accounting
Use of Estimates
−Removed: Our discussion and analysis
−Removed: of our financial condition and results of operations are based upon our condensed consolidated financial statements, which have been prepared
−Removed: in accordance with accounting principles generally accepted in the United States.
−Removed: The preparation of these condensed consolidated financial
−Removed: statements requires us to make estimates and judgments that affect the reported amounts of assets, liabilities, revenues and expenses,
−Removed: and related disclosure of contingent assets and liabilities.
−Removed: We continually evaluate our estimates, including those related to the useful
−Removed: life of property and equipment and investment in real estate, assumptions used in assessing impairment of long-term assets, valuation
−Removed: of deferred tax assets and the associated valuation allowances, and valuation of stock-based compensation.
+Added: Our discussion and analysis of our financial
+Added: condition and results of operations are based upon our condensed consolidated financial statements, which have been prepared in accordance
+Added: with accounting principles generally accepted in the United States.
+Added: The preparation of these condensed consolidated financial statements
+Added: requires us to make estimates and judgments that affect the reported amounts of assets, liabilities, revenues and expenses, and related
+Added: disclosure of contingent assets and liabilities.
+Added: We continually evaluate our estimates, including those related to the useful life of
+Added: property and equipment and investment in real estate, assumptions used in assessing impairment of long-term assets, valuation of deferred
+Added: tax assets and the associated valuation allowances, and valuation of stock-based compensation, and assumptions used to determine fair
+Added: value of warrants and embedded conversion features of convertible note payable.
We base our estimates
5 unchanged sentences
Revenue Recognition
−Removed: recognize revenue under Accounting Standards Codification (“ASC”) Topic 606, Revenue from Contracts with Customers (“ASC
−Removed: The core principle of the revenue standard is that a company should recognize revenue to depict the transfer of promised
−Removed: goods or services to customers in an amount that reflects the consideration to which the company expects to be entitled in exchange for
−Removed: those goods or services.
+Added: We recognize revenue
+Added: under Accounting Standards Codification (“ASC”) Topic 606, Revenue from Contracts with Customers (“ASC 606”).
+Added: The core principle of the revenue standard is that a company should recognize revenue to depict the transfer of promised goods or services
+Added: to customers in an amount that reflects the consideration to which the company expects to be enti tled
+Added: in exchange for those goods or services.
The following five steps are applied to achieve that core principle:
4 unchanged sentences
Recognize revenue when the company satisfies a performance obligation
−Removed: In order to identify the performance obligations
−Removed: in a contract with a customer, a company must assess the promised goods or services in the contract and identify each promised goods or
−Removed: service that is distinct.
−Removed: A performance obligation meets ASC 606’s definition of a “distinct” goods or service (or bundle
−Removed: of goods or services) if both of the following criteria are met:
−Removed: ● The customer can benefit from the goods or service either on its own or together with other resources
−Removed: that are readily available to the customer (i.e., the goods or service is capable of being distinct).
−Removed: ● The entity’s promise to transfer the goods or service to the customer is separately identifiable
−Removed: from other promises in the contract (i.e., the promise to transfer the goods or service is distinct within the context of the contract).
−Removed: If a goods or service is not distinct, the goods
−Removed: or service is combined with other promised goods or services until a bundle of goods or services is identified that is distinct.
+Added: order to id entify the performance obligations in a contract with a customer, a company must assess the promised goods or services
+Added: in the contract and identify each promised goods or service that is distinct.
+Added: A performance obligation meets ASC 606’s defin ition
+Added: of a “distinct” goods or service (or bundle of goods or services) if both of the following criteria are met:
+Added: customer can benefit from the goods or service either on its own or together with other resources
+Added: that are readily available to the customer (i.e., the goods or service is capable of being
+Added: entity’s promise to transfer the goods or service to the customer is separately identifiable
+Added: from other promises in the contract (i.e., the promise to transfer the goods or service is
+Added: distinct within the context of the contract).
+Added: a goods or service is not distinct, the goods or service is combined with other promised goods or services until a bundle of goods
+Added: or services is identified that is distinct.
The transaction price is the amount of consideration
10 unchanged sentences
when that performance obligation is satisfied, at a point in time or over time as appropriate.
−Removed: The Company’s revenues
−Removed: are derived from providing medial related consulting services for its’ related parties.
−Removed: Revenues related to its service offerings
−Removed: are recognized at a point in time when service is rendered.
−Removed: Any payments received in advance of the performance of services are recorded
−Removed: as deferred revenue until such time as the services are performed.
+Added: The Company’s
+Added: revenues are derived from providing medial related consulting services for its’ related parties.
+Added: Revenues related to its service
+Added: offerings are recognized at a point in time when service is rendered.
+Added: Any payments received in advance of the performance of services
+Added: are recorded as deferred revenue until such time as the services are performed.
We have determined that
4 unchanged sentences
basis over the term of the related leases.
−Removed: The cumulative difference between lease revenue recognized under the straight-line method and
−Removed: contractual lease payments are included in rent receivable on the condensed consolidated balance sheets.
+Added: The cumulative difference between lease revenue recognized under the straight-line method
+Added: and contractual lease payments are included in rent receivable on the condensed consolidated balance sheets.
We do not offer promotional
27 unchanged sentences
Comparison of Results of Operations for the
−Removed: Three Months Ended March 31, 2022 and 2021
+Added: Three and Six Months Ended June 30, 2022 and 2021
For the three months
−Removed: ended March 31, 2022, we had real property rental revenue of $297,631, as compared to $289,774 for the three months ended March 31, 2021,
+Added: ended June 30, 2022, we had real property rental revenue of $290,821, as compared to $280,232 for the three months ended June 30, 2021,
an increase of $10,589, or 3.8%.
−Removed: The slight increase was primarily attributable to the increase of tenants in the first quarter of 2021.
−Removed: We expect that our revenue from real property rent will remain in its current level with minimal increase in the near future.
+Added: For the six months ended June 30, 2022, we had real property rental revenue of $588,452, as compared
+Added: to $570,006 for the six months ended June 30, 2021, an increase of $18,446, or 3.2%.
+Added: The slight increase was primarily attributable to
+Added: the increase of tenants in the first half of 2022.
+Added: We expect that our revenue from real property rent will remain in its current quarterly
+Added: level with minimal increase in the near future.
Costs and Expenses
3 unchanged sentences
For the three months
−Removed: ended March 31, 2022, our real property operating expenses amounted to $218,448, as compared to $216,894 for the three months ended March
+Added: ended June 30, 2022, our real property operating expenses amounted to $211,703, as compared to $205,147 for the three months ended June
30, 2021, an increase of $6,556, or 3.2%.
+Added: For the six months ended
+Added: June 30, 2022, our real property operating expenses amounted to $430,151, as compared to $422,041 for the six months ended June 30, 2021,
+Added: an increase of $8,110, or 1.9%.
Real Property Operating Income
−Removed: property operating income for the three months ended March 31, 2022 was $79,183, representing an increase of $6,303, or 8.6%, as compared
−Removed: to $72,880 for the three months ended March 31, 2021.
−Removed: The increase was mainly attributable to the increase in real property rental revenue
−Removed: as described above.
−Removed: We expect our real property operating income will remain in its current level with minimal increase in the near future.
+Added: Our real property operating income for the three
+Added: months ended June 30, 2022 was $79,118, representing an increase of $4,033, or 5.4%, as compared to $75,085 for the three months ended
+Added: June 30, 2021.
+Added: Our real property operating income for the six months ended June 30, 2022 was $158,301, representing an increase of $10,336,
+Added: or 7.0%, as compared to $147,965 for the six months ended June 30, 2021.
+Added: The increase was mainly attributable to the increase in real
+Added: property rental revenue as described above.
+Added: We expect our real property operating income will remain in its current quarterly level with
+Added: minimal increase in the near future.
Other Operating Expenses
−Removed: the three months ended March 31, 2022 and 2021, other operating expenses consisted of the following:
+Added: For the three and six
+Added: months ended June 30, 2022 and 2021, other operating expenses consisted of the following:
Three Months Ended
+Added: Six Months Ended
Advertising and marketing expenses
2 unchanged sentences
Research and development
−Removed: Travel and entertainment
+Added: Litigation settlement
Directors and officers liability insurance premium
+Added: Travel and entertainment
Rent and related utilities
Other general and administrative
−Removed: ● For the three months ended March 31, 2022, advertising and
−Removed: marketing expenses increased by $517,983 or 5,870.8% as compared to the three months ended March 31, 2021.
−Removed: The increase was primarily
−Removed: due to increased advertising activities.
−Removed: We expect that our advertising expenses will decrease in the near future.
−Removed: ● Professional fees primarily consisted of accounting fees, audit
−Removed: fees, legal service fees, consulting fees, investor relations service charges and other fees.
−Removed: For the three months ended March 31, 2022,
−Removed: professional fees decreased by $559,870, or 40.5%, as compared to the three months ended March 31, 2021.
−Removed: The decrease was primarily attributable
−Removed: to a decrease in consulting fees of approximately $476,000 mainly due to the decrease in use of consulting service providers, a decrease
−Removed: in legal service fees of approximately $111,000 mainly due to the decrease in use of legal service providers, and a decrease in valuation
−Removed: service fee of $90,000, offset by an increase in investor relations service fees of approximately $107,000 mainly due to the increase
−Removed: in use of investor relations service providers, and an increase in other miscellaneous items of approximately $10,000.
−Removed: We expect that
−Removed: our professional fees will remain in its current level with minimal increase in the near future.
−Removed: ● For the three months ended March 31, 2022, compensation and
−Removed: related benefits decreased by $38,961, or 6.9%, as compared to the three months ended March 31, 2021.
−Removed: The decrease was primarily attributable
−Removed: to a decrease in stock-based compensation of approximately $35,000 which reflected the value of options granted and vested to our management
+Added: three months ended June 30, 2022, advertising and marketing expenses increased by $122,895
+Added: or 1,638.6% as compared to the three months ended June 30, 2021.
+Added: For the six months
+Added: ended June 30, 2022, advertising and marketing expenses increased by $640,878 or 3,926.2%
+Added: as compared to the six months ended June 30, 2021.
+Added: The increase was primarily due to increased
+Added: advertising activities.
+Added: We expect that our advertising expenses will remain in its current
+Added: quarterly level with minimal increase in the near future.
+Added: ● Professional
+Added: fees primarily consisted of accounting fees, audit fees, legal service fees, consulting fees,
+Added: investor relations service charges, valuation service fees and other fees.
+Added: For the three
+Added: months ended June 30, 2022, professional fees decreased by $920,632, or 67.8%, as compared
+Added: to the three months ended June 30, 2021, which was primarily attributable to a decrease in
+Added: consulting fees of approximately $410,000 mainly due to the decrease in use of consulting
+Added: service providers, a decrease in legal service fees of approximately $381,000 mainly due
+Added: to the decrease in use of legal service providers, a decrease in investor relations service
+Added: charges of $81,000 mainly due to the decrease in use of investor relations service providers,
+Added: and a decrease in valuation service fees of $90,000, offset by an increase in in other miscellaneous
+Added: items of approximately $41,000.
+Added: For the six months ended June 30, 2022, professional fees
+Added: decreased by $1,480,502, or 54.1%, as compared to the six months ended June 30, 2021, which
+Added: was primarily attributable to a decrease in consulting fees of approximately $886,000 mainly
+Added: due to the decrease in use of consulting service providers, a decrease in legal service fees
+Added: of approximately $492,000 mainly due to the decrease in use of legal service providers, and
+Added: a decrease in one time valuation service fees of $180,000, offset by an increase in other
+Added: miscellaneous items of approximately $77,000.
+Added: We expect that our professional fees will remain
+Added: in its current quarterly level with minimal increase in the near future.
+Added: three months ended June 30, 2022, compensation and related benefits decreased by $44,288,
+Added: or 8.1%, as compared to the three months ended June 30, 2021, which was primarily attributable
+Added: to a decrease in stock-based compensation of approximately $43,000 which reflected the value
+Added: of options granted and vested to our management and a decrease in management’s compensation
+Added: and related benefits of approximately $1,000.
+Added: For the six months ended June 30, 2022,
+Added: compensation and related benefits decreased by $83,249, or 7.5%, as compared to the six months
+Added: ended June 30, 2021, which was primarily attributable to a decrease in stock-based compensation
+Added: of approximately $78,000 which reflected the value of options granted and vested to our management
and a decrease in management’s compensation and related benefits of approximately $5,000.
−Removed: We expect that our compensation and related
−Removed: benefits will remain in its current level with minimal decrease in the near future.
−Removed: ● For the three months ended March 31, 2022, research and development
−Removed: expenses decreased by $96,504, or 45.3%, as compared to the three months ended March 31, 2021.
−Removed: The decrease was mainly attributable to
−Removed: we decreased research and development projects in the first quarter of 2022.
−Removed: We expect that our research and development expenses will
−Removed: continue to decrease in the near future.
−Removed: ● For the three months ended March 31, 2022, travel and entertainment
−Removed: expense increased by $6,130, or 19.1%, as compared to the three months ended March 31, 2021.
−Removed: The increase was mainly due to increased
−Removed: business travel activities in the first quarter of 2022.
−Removed: ● For the three months ended March 31, 2022, Directors and Officers
−Removed: Liability Insurance premium increased by $22,443, or 27.7%, as compared to the three months ended March 31, 2021.
−Removed: The increase was mainly
−Removed: due to different insurance provider with different premium.
−Removed: ● For the three months ended March 31, 2022, rent and related utilities
−Removed: expenses decreased by $2,071, or 9.2%, as compared to the three months ended March 31, 2021.
−Removed: The decrease was mainly due to the decreased
−Removed: monthly rent in Avalon Shanghai’s office.
−Removed: ● Other general and administrative expenses mainly consisted
−Removed: of NASDAQ listing fee, office supplies, and other miscellaneous items.
−Removed: For the three months ended March 31, 2022, other general and administrative
−Removed: expenses decreased by $19,493, or 25.9%, as compared to the three months ended March 31, 2021, reflecting our efforts at stricter controls
−Removed: on corporate expenditure.
+Added: We expect that our compensation and related benefits will remain in its current quarterly
+Added: level with minimal decrease in the near future.
+Added: three months ended June 30, 2022, research and development expenses increased by $15,683,
+Added: or 6.6%, as compared to the three months ended June 30, 2021.
+Added: The increase was mainly attributable
+Added: to we increased research and development projects in the second quarter of 2022.
+Added: six months ended June 30, 2022, research and development expenses decreased by $80,821, or
+Added: 17.9%, as compared to the six months ended June 30, 2021.
+Added: The decrease was mainly attributable
+Added: to we decreased research and development projects in the first half of 2022.
+Added: We expect that
+Added: our research and development expenses will remain in its current quarterly level with minimal
+Added: decrease in the near future.
+Added: ● For the three months ended June 30, 2022, litigation settlement increased by
+Added: $1,350,000, or 100.0%, as compared to the three months ended June 30, 2021.
+Added: For the six months ended June 30, 2022, litigation settlement
+Added: increased by $1,350,000, or 100.0%, as compared to the six months ended June 30, 2021.
+Added: The increase was due to a settlement signed in
+Added: three months ended June 30, 2022, Directors and Officers Liability Insurance premium increased
+Added: by $22,443, or 27.7%, as compared to the three months ended June 30, 2021.
+Added: months ended June 30, 2022, Directors and Officers Liability Insurance premium increased
+Added: by $44,886, or 27.7%, as compared to the six months ended June 30, 2021.
+Added: The increase was
+Added: mainly due to different insurance provider with different premium.
+Added: three months ended June 30, 2022, travel and entertainment expense increased by $1,213, or
+Added: 3.0%, as compared to the three months ended June 30, 2021.
+Added: For the six months ended
+Added: June 30, 2022, travel and entertainment expense increased by $7,343, or 10.2%, as compared
+Added: to the six months ended June 30, 2021.
+Added: The increase was mainly due to increased business
+Added: travel activities in the first half of 2022.
+Added: the three months ended June 30, 2022, rent and related utilities expenses increased by $995,
+Added: or 5.3%, as compared to the three months ended June 30, 2021.
+Added: For the six months ended June
+Added: 30, 2022, rent and related utilities expenses decreased by $1,076, or 2.6%, as compared to
+Added: the six months ended June 30, 2021.
+Added: ● Other general
+Added: and administrative expenses mainly consisted of NASDAQ listing fee, office supplies, and
+Added: other miscellaneous items.
+Added: For the three months ended June 30, 2022, other general and administrative
+Added: expenses decreased by $2,985, or 3.5%, as compared to the three months ended June 30, 2021.
+Added: For the six months ended June 30, 2022, other general and administrative expenses decreased
+Added: by $22,478, or13.9%, as compared to the six months ended June 30, 2021.
+Added: The decrease was
+Added: mainly due to our efforts at stricter controls on corporate expenditure.
Loss from Operations
−Removed: a result of the foregoing, for the three months ended March 31, 2022, loss from operations amounted to $2,126,942, as compared to $2,303,588
−Removed: for the three months ended March 31, 2021, a decrease of $176,646 or 7.7%.
+Added: As a result of the foregoing,
+Added: for the three months ended June 30, 2022, loss from operations amounted to $2,843,571, as compared to $2,302,280 for the three months
+Added: ended June 30, 2021, an increase of $541,291 or 23.5%.
+Added: As a result of the foregoing,
+Added: for the six months ended June 30, 2022, loss from operations amounted to $4,970,513, as compared to $4,605,868 for the six months ended
+Added: June 30, 2021, an increase of $364,645 or 7.9%.
Other (Expense)
Other (expense) income
−Removed: mainly includes interest expense, loss from equity method investment, and other miscellaneous income.
+Added: mainly includes interest expense, loss from equity method investment, change in fair value of derivative liability, and other miscellaneous income (expense).
Other income, net, totaled
−Removed: $56,404 for the three months ended March 31, 2022, as compared to other expense, net, of $63,530 for the three months ended March 31,
−Removed: 2021, a change of $119,934, or 188.8%, which was primarily attributable to a decrease in interest expense of approximately $5,000, and
−Removed: a decrease in loss from equity method investment of approximately $6,000, and an increase in other miscellaneous income of approximately
−Removed: have any income taxes expense for the three months ended March 31, 2022 and 2021 since we incurred losses in these periods.
−Removed: of the factors described above, our net loss was $2,070,538 for the three months ended March 31, 2022, as compared to $2,367,118 for the
−Removed: three months ended March 31, 2021, a decrease of $296,580 or 12.5%.
+Added: $815,097 for the three months ended June 30, 2022, as compared to other expense, net, of $62,630 for the three months ended June 30,
+Added: 2021, a change of $877,727, or 1,401.4%, which was primarily attributable to an increase in other miscellaneous income of approximately
+Added: $153,000 mainly driven by reagent sale in the second quarter of 2022, an increase in gain from change in fair value of derivative liability
+Added: of approximately $769,000, and a decrease in loss from equity method investment of approximately $4,000, offset by an increase in interest
+Added: expense of approximately $48,000 due to the increase in outstanding borrowings.
+Added: Other income, net, totaled
+Added: $871,501 for the six months ended June 30, 2022, as compared to other expense, net, of $126,160 for the six months ended June 30, 2021,
+Added: a change of $997,661, or 790.8%, which was primarily attributable to an increase in other miscellaneous income of approximately $261,000
+Added: mainly driven by reagent sale in the first half of 2022, an increase in gain from change in fair value of derivative liability of approximately
+Added: $769,000, and a decrease in loss from equity method investment of approximately $9,000, offset by an increase in interest expense of
+Added: approximately $42,000 due to the increase in outstanding borrowings.
+Added: We did not have any income taxes expense for
+Added: the three months ended June 30, 2022 and 2021 since we incurred losses in these periods.
+Added: We did not have any income taxes expense for
+Added: the six months ended June 30, 2022 and 2021 since we incurred losses in these periods.
+Added: of the factors described above, our net loss was $2,028,474 for the three months ended June 30, 2022, as compared to $2,364,910 for the
+Added: three months ended June 30, 2021, a decrease of $336,436 or 14.2%.
+Added: of the factors described above, our net loss was $4,099,012 for the six months ended June 30, 2022, as compared to $4,732,028 for the
+Added: six months ended June 30, 2021, a decrease of $633,016 or 13.4%.
Net Loss Attributable to Avalon GloboCare
2 unchanged sentences
common shareholders was $2,028,474 or $0.02 per share (basic and diluted) for the three months
−Removed: ended March 31, 2022, as compared with $2,367,118, or $0.03 per share (basic and diluted) for the three months ended March 31, 2021, a
−Removed: change of $296,580 or 12.5%.
+Added: ended June 30, 2022, as compared with $2,364,910, or $0.03 per share (basic and diluted) for the three months ended June 30, 2021, a change
+Added: of $336,436 or 14.2%.
+Added: loss attributable to Avalon GloboCare Corp.
+Added: common shareholders was $4,099,012 or $0.05 per share (basic and diluted) for the six months
+Added: ended June 30, 2022, as compared with $4,732,028, or $0.06 per share (basic and diluted) for the six months ended June 30, 2021, a change
+Added: of $633,016 or 13.4%.
Foreign Currency Translation Adjustment
9 unchanged sentences
As a result of
−Removed: foreign currency translations, which are a non-cash adjustment, we reported a foreign currency translation gain of $2,021 and a foreign
−Removed: currency translation loss of $2,722 for the three months ended March 31, 2022 and 2021, respectively.
−Removed: This non-cash gain/loss had the
−Removed: effect of decreasing/increasing our reported comprehensive loss.
+Added: foreign currency translations, which are a non-cash adjustment, we reported a foreign currency translation loss of $43,503 and a foreign
+Added: currency translation gain of $14,786 for the three months ended June 30, 2022 and 2021, respectively.
+Added: As a result of foreign currency
+Added: translations, which are a non-cash adjustment, we reported a foreign currency translation loss of $41,482 and a foreign currency translation
+Added: gain of $12,064 for the six months ended June 30, 2022 and 2021, respectively.
+Added: This non-cash loss/gain had the effect of increasing/decreasing
+Added: our reported comprehensive loss.
Comprehensive Loss
As a result of our foreign
−Removed: currency translation adjustment, we had comprehensive loss of $2,068,517 and $2,369,840 for the three months ended March 31, 2022 and
+Added: currency translation adjustment, we had comprehensive loss of $2,071,977 and $2,350,124 for the three months ended June 30, 2022 and 2021,
respectively.
+Added: As a result of our foreign
+Added: currency translation adjustment, we had comprehensive loss of $4,140,494 and $4,719,964 for the six months ended June 30, 2022 and 2021,
+Added: respectively.
Liquidity and Capital Resources
25 unchanged sentences
of a company to generate funds to support its current and future operations, satisfy its obligations and otherwise operate on an ongoing
−Removed: At March 31, 2022 and December 31, 2021, we had cash balance of approximately $526,000 and $808,000, respectively.
−Removed: are kept in financial institutions located as follows:
−Removed: March 31, 2022
+Added: At June 30, 2022 and December 31, 2021, we had cash balance of approximately $1,180,000 and $808,000, respectively.
+Added: funds are kept in financial institutions located as follows:
+Added: June 30, 2022
December 31, 2021
21 unchanged sentences
The following table sets
−Removed: forth a summary of changes in our working capital from December 31, 2021 to March 31, 2022:
+Added: forth a summary of changes in our working capital from December 31, 2021 to June 30, 2022:
Working capital deficit:
5 unchanged sentences
$ (2,478,854 )
−Removed: Our working capital deficit
−Removed: increased by $1,155,754 to $4,234,370 at March 31, 2022 from $3,078,616 at December 31, 2021.
−Removed: The increase in working capital deficit
−Removed: was primarily attributable to a decrease in cash of approximately $281,000, a decrease in prepaid expenses and other current assets of
−Removed: approximately $152,000, an increase in accrued professional fees of approximately $686,000, an increase in accrued payroll liability and
−Removed: directors’ compensation of approximately $173,000, and an increase in accrued liabilities and other payables of approximately $382,000,
−Removed: offset by a decrease in accrued research and development fees of approximately $116,000 and a decrease in note payable – related
−Removed: party of $390,000 resulting from the reclassification of note payable – related party from current to non-current.
+Added: Our working capital
+Added: deficit increased by $2,478,854 to $5,557,470 at June 30, 2022 from $3,078,616 at December 31, 2021.
+Added: The increase in working
+Added: capital deficit was primarily attributable to an increase in accounts payable of approximately $376,000, an increase in accrued
+Added: settlement of lawsuit of $900,000 due to a settlement signed in June 2022, an increase in convertible note payable, net,
+Added: of approximately $493,000 resulting from the issuance of 2022 Convertible Note, and an increase in derivative liability of
+Added: approximately $2,013,000 which was related to our 2022 Convertible Note, offset by an increase in cash of approximately $373,000, a
+Added: decrease in accrued professional fees of approximately $396,000, which was mainly due to payments made to our professional service
+Added: providers in the first half of 2022, a decrease in accrued research and development fees of approximately $319,000 resulting from
+Added: payments made to research and development service provider in the six months ended June 30, 2022 , and a decrease in note payable
+Added: – related party of $390,000 due to repayment made to this related party in the first half of 2022.
Because the exchange
2 unchanged sentences
the comparable changes reflected on the condensed consolidated balance sheets.
−Removed: Cash Flows for the Three Months Ended March
−Removed: 31, 2022 Compared to the Three Months Ended March 31, 2021
+Added: Cash Flows for the Six Months Ended June 30,
+Added: 2022 Compared to the Six Months Ended June 30, 2021
The following summarizes the key components of
−Removed: our cash flows for the three months ended March 31, 2022 and 2021:
−Removed: Three Months Ended
+Added: our cash flows for the six months ended June 30, 2022 and 2021:
+Added: Six Months Ended
Net cash used in operating activities
$ (2,686,722 )
+Added: $ (2,593,548 )
Net cash used in investing activities
1 unchanged sentence
Effect of exchange rate on cash
−Removed: Net (decrease) increase in cash
−Removed: Net cash flow used in
−Removed: operating activities for the three months ended March 31, 2022 was $511,208, which primarily reflected our consolidated net loss of approximately
−Removed: $2,071,000, and the changes in operating assets and liabilities, primarily consisting of a decrease in operating lease obligation of approximately
−Removed: $34,000, offset by a decrease in prepaid expenses and other assets of approximately $30,000, an increase accrued liabilities and other
−Removed: payables of approximately $794,000, and an increase in accrued liabilities and other payables – related parties of approximately
−Removed: $40,000, and the non-cash items adjustment primarily consisting of depreciation of approximately $85,000, amortization of right-of-use
−Removed: asset of approximately $34,000, and stock-based compensation and service expense of approximately $606,000.
−Removed: Net cash flow used in
−Removed: operating activities for the three months ended March 31, 2021 was $1,515,525, which primarily reflected our consolidated net loss of
−Removed: approximately $2,367,000, and the changes in operating assets and liabilities, primarily consisting of an increase in prepaid expenses
−Removed: and other assets of approximately $41,000, and a decrease in operating lease obligation of approximately $33,000, offset by an increase
−Removed: in accrued liabilities and other payables of approximately $163,000, an increase in accrued liabilities and other payables – related
−Removed: parties of approximately $45,000, and the non-cash items adjustment primarily consisting of depreciation of approximately $79,000, and
−Removed: stock-based compensation and service expense of approximately $574,000.
+Added: Net increase (decrease) in cash
+Added: Net cash flow used
+Added: in operating activities for the six months ended June 30, 2022 was $2,686,722, which primarily reflected our consolidated net loss
+Added: of approximately $4,099,000, and the non-cash item adjustment consisting of change in fair market value of derivative liability of
+Added: approximately $769,000, and the changes in operating assets and liabilities, primarily consisting of a decrease in operating lease
+Added: obligation of approximately $80,000, offset by an increase in accounts payable of approximately $389,000, an increase in accrued
+Added: liabilities and other payables of approximately $675,000, which was mainly attributable the increase in accrued settlement of
+Added: lawsuit of $1,350,000 resulting from a settlement signed in June 2022 offset by the decrease in accrued professional fees
+Added: of approximately $396,000 due to payments made to our professional service providers in the first half of 2022 and the decrease in
+Added: accrued research and development fees of approximately $319,000 resulting from payments made to research and development service
+Added: provider in the six months ended June 30, 2022, and an increase in accrued liabilities and other payables – related parties of
+Added: approximately $72,000, and the non-cash items adjustment primarily consisting of depreciation of approximately $169,000,
+Added: amortization of right-of-use asset of approximately $68,000, stock-based compensation and service expense of approximately $821,000,
+Added: and amortization of debt discount of approximately $55,000.
+Added: cash flow used in operating activities for the six months ended June 30, 2021 was $2,593,548, which primarily reflected our consolidated
+Added: net loss of approximately $4,732,000, and the changes in operating assets and liabilities, primarily consisting of a decrease in operating
+Added: lease obligation of approximately $60,000, offset by an increase accrued liabilities and other payables of approximately $714,000, and
+Added: an increase in accrued liabilities and other payables – related parties of approximately $91,000, and the non-cash items adjustment
+Added: primarily consisting of depreciation of approximately $141,000, amortization of right-of-use asset of approximately $60,000, and stock-based
+Added: compensation and service expense of approximately $1,087,000.
We expect our cash
2 unchanged sentences
● an increase in professional staff and services;
−Removed: ● an increase in public relations and/or sales promotions for existing and/or new brands as we expand
−Removed: within existing markets or enter new markets.
+Added: ● an increase in public relations and/or sales promotions
+Added: for existing and/or new brands as we expand within existing markets or enter new markets.
Net cash flow used in
−Removed: investing activities was $1,749 for the three months ended March 31, 2022 as compared to $30,844 for the three months ended March
−Removed: During the three months ended March 31, 2022, we made payments for purchase of property and equipment of approximately $2,000.
−Removed: the three months ended March 31, 2021, we made additional investment in equity method investment of approximately $31,000.
+Added: investing activities was $55,757 for the six months ended June 30, 2022 as compared to $50,511 for the six months ended June 30,
+Added: During the six months ended June 30, 2022, we made payments for purchase of property and equipment of approximately $2,000 and made
+Added: additional investment in equity method investment of approximately $54,000.
+Added: During the six
+Added: months ended June 30, 2021, we made payment for improvement of commercial real estate of approximately $10,000 and made additional investment
+Added: in equity method investment of approximately $40,000.
Net cash flow provided
−Removed: by financing activities was $231,500 for the three months ended March 31, 2022 as compared to $2,512,212 for the three months ended March
−Removed: During the three months ended March 31, 2022, we received proceeds from related party borrowings of approximately $100,000 and
−Removed: net proceeds from equity offering of approximately $132,000 (net of cash paid for commission of approximately $4,000).
−Removed: During the three
−Removed: months ended March 31, 2021, we received proceeds from related party borrowings of approximately $105,000 and net proceeds from equity
−Removed: offering of approximately $2,407,000 (net of cash paid for commission of approximately $74,000).
+Added: by financing activities was $3,130,443 for the six months ended June 30, 2022 as compared to $2,600,151 for the six months ended June
+Added: During the six months ended June 30, 2022, we received proceeds from related party borrowings of approximately $100,000 and
+Added: net proceeds from equity offering of approximately $112,000 (net of cash paid for commission and other offering costs of approximately
+Added: $24,000) and proceeds from issuance of convertible debt and warrants of approximately $3,719,000 to fund our working capital needs, offset
+Added: by repayments made for note payable – related party of $390,000 and repayments made for loan
+Added: payable – related party of $410,000.
+Added: During the six months ended June 30, 2021, we received proceeds from related party borrowings
+Added: of approximately $193,000 and net proceeds from equity offering of approximately $2,407,000 (net of cash paid for commission of approximately
Our capital requirements
6 unchanged sentences
in our liquidity over the near to long term:
−Removed: ● an increase in working capital requirements to finance our current business, including ongoing research
−Removed: and development programs, clinical studies, as well as commercial strategies;
−Removed: ● the use of capital for mergers, acquisitions and the development of business opportunities;
+Added: ● an increase in working capital requirements to finance our
+Added: current business, including ongoing research and development programs, clinical studies, as well as commercial strategies;
+Added: use of capital for mergers, acquisitions and the development of business opportunities;
● addition of administrative personnel as the business grows;
4 unchanged sentences
bears interest at a rate of 5% and provides for maturity on drawn loans 36 months after funding.
−Removed: As of March 31, 2022, the total principal
+Added: As of June 30, 2022, the total principal
amount outstanding under the Credit Line was $2.4 million and we have approximately $14.1 million remaining available under the Line
19 unchanged sentences
price of up to $13,000,000 from time to time through Jefferies acting as our sales agent in accordance with the terms of the sales
−Removed: As of March 31, 2022, we sold a total of 6,429,486 shares of our common stock through Jefferies with an aggregate offering
−Removed: price of $10,073,707 and we have approximately $4.9 million offering price remaining available under the Sales Agreement.
+Added: As of June 30, 2022, we sold a total of 6,429,486 shares of our common stock through Jefferies with an aggregate offering price
+Added: of $10,073,707 and we have approximately $4.9 million offering price remaining available under the Sales Agreement.
We estimate that based
34 unchanged sentences
of operations, and cash flows.
−Removed: The following tables summarize our contractual obligations as of March 31, 2022, and the effect these obligations
+Added: The following tables summarize our contractual obligations as of June 30, 2022, and the effect these obligations
are expected to have on our liquidity and cash flows in future periods.
1 unchanged sentence
Contractual obligations:
+Added: Less than 1 year
Operating lease commitment
2 unchanged sentences
Accrued interest – related party
+Added: Convertible debt
+Added: Accrued interest for convertible debt
Epicon equity investment obligation
−Removed: AVAR joint venture commitment
+Added: Avactis joint venture commitment
Off-balance Sheet Arrangements
4 unchanged sentences
RMB and US dollars.
−Removed: For the three months ended March 31, 2022 and 2021, we had an unrealized foreign currency translation gain of approximately
−Removed: $2,000 and an unrealized foreign currency translation loss of approximately $3,000, respectively, because of changes in the exchange rate.
+Added: For the three months ended June 30, 2022 and 2021, we had an unrealized foreign currency translation loss of approximately
+Added: $44,000 and an unrealized foreign currency translation gain of approximately $15,000, respectively, because of changes in the exchange
+Added: For the six months ended June 30, 2022 and 2021, we had an unrealized foreign currency translation loss of approximately $42,000
+Added: and an unrealized foreign currency translation gain of approximately $12,000, respectively, because of changes in the exchange rate.
The effect of inflation on our revenue and operating
4 unchanged sentences
Compared sentence by sentence after normalising whitespace, quotation marks, case and digits, so re-formatting and restated figures do not read as changed language. Wording changes appear as one removal and one addition. The current filing and the prior one are authoritative.