16 unchanged sentences
2 - Results of Operations .
−Removed: This section provides an analysis of our results of operations for the first half and second quarter
−Removed: of fiscal 2026 in comparison to the first half and second quarter of fiscal 2025.
+Added: This section provides an analysis of our results of operations for the nine months and third quarter
+Added: of fiscal 2026 in comparison to the nine months and third quarter of fiscal 2025.
3 - Financial Liquidity and Capital Resources.
3 unchanged sentences
Our unaudited Condensed Consolidated
−Removed: Financial Statements, and the financial information contained herein, are reported in U.S Dollars.
+Added: Financial Statements, and the financial information contained herein, are reported in U.S.
Note Regarding Forward-Looking Statements
48 unchanged sentences
commencing trading on the Toronto Stock Exchange and Nasdaq on that date.
−Removed: Throughout this time period, there
−Removed: were several important updated on the ongoing pivotal Phase 3 study of Bria-IMT™ in patients with advanced metastatic breast cancer,
−Removed: including accelerating enrollment, adding additional clinical sites, and several positive Data Safety Monitoring Board meetings.
−Removed: of these are detailed below.
+Added: this time period, there were several important updates on the ongoing pivotal Phase 3 study of Bria-IMT™ in patients with
+Added: advanced metastatic breast cancer, including accelerating enrollment, adding additional clinical sites, and several positive Data
+Added: Safety Monitoring Board meetings.
+Added: Some of these are detailed below.
also strengthened our non-dilutive funding and external collaborations.
9 unchanged sentences
November 25, 2025, BriaCell highlighted positive Phase 2 & Phase 3 clinical data at SABCS® 2025 with poster presentations at
−Removed: the San Antonio Breast Cancer Symposium (December 10, 2025) will highlight positive Phase 2 safety and efficacy signals and positive
−Removed: biomarker findings in both the Phase 2 and the pivotal Phase 3 studies.On December 9 , 2025, BriaCell announced that patient
−Removed: enrollment is on track for 1H2026 topline data readout with over 230 patients screened and over 160 patients enrolled in BriaCell’s
−Removed: pivotal Phase 3 study in metastatic breast cancer (MBC).
−Removed: Survival Results of Phase II Bria-IMT Allogenic Whole Cell-Based Cancer Vaccine
−Removed: positive Phase 2 data continue to support the potentially meaningful clinical benefit of the Bria-IMT regimen and the ongoing pivotal
−Removed: Phase 3 study is further evaluating this immunotherapy and the role of biomarkers in predicting patient response.
+Added: the San Antonio Breast Cancer Symposium (December 10, 2025) which highlighted positive Phase 2 safety and efficacy signals and
+Added: positive biomarker findings in both the Phase 2 and the pivotal Phase 3 studies.
+Added: On December 9 , 2025, BriaCell announced
+Added: that patient enrollment is on track for 1H2026 topline data readout with over 230 patients screened and over 160 patients enrolled
+Added: in BriaCell’s pivotal Phase 3 study in metastatic breast cancer (MBC).
+Added: Survival Results of Phase II Bria-IMT Allogenic Whole Cell-Based Cancer Vaccine Maturing positive Phase 2 data continue to
+Added: support the potentially meaningful clinical benefit of the Bria-IMT regimen and the ongoing pivotal Phase 3 study is further
+Added: evaluating this immunotherapy and the role of biomarkers in predicting patient response.
Th1-biased cytokine signatures as biomarkers of clinical benefit following SV-BR-1-GM cancer vaccination in breast cancer.
133 unchanged sentences
Bria-IMT regimen continues under Fast Track Designation from US FDA.
+Added: On February 17, 2026, BriaCell received its fifth
+Added: positive recommendation from Data Safety Monitoring Board (DSMB) for Phase 3 study in metastatic breast cancer.
+Added: Independent DSMB has identified
+Added: no safety concerns, and recommended continuation of BriaCell’s pivotal Phase 3 study of Bria-IMT™ plus immune check point
+Added: This fifth consecutive positive DSMB recommendation supports the favorable safety profile observed to date.
+Added: On April 20, 2026, BriaCell presented positive Phase
+Added: 3 quality of life (QOL) data in heavily pretreated metastatic breast cancer patients with prior failed ADC, CPI, and CDK4/6 inhibitor
+Added: treatments at the 2026 American Association for Cancer Research (AACR) annual meeting.
+Added: The data showed preservation of quality QOL in
+Added: patients who had been on multiple prior failed therapy attempts.
+Added: Additionally, we showed identification of potential prognostic biomarkers
+Added: upon further analyses of Phase 2 Bria-IMT™ study data.
+Added: On April 27, 2026, BriaCell announced that it has
+Added: six clinical data presentations at the American Society of Clinical Oncology (ASCO 2026) meeting.
+Added: On May 7, 2026, and May 13, 2026, BriaCell
+Added: announced the addition of NYU Langone Health’s Perlmutter Cancer Center and Penn Medicine’s Abramson Cancer Center, respectively, as clinical
+Added: sites in the Bria-ABC pivotal breast cancer study.
+Added: On May 12, 2026, BriaCell announced that enrollment in that the Bria-ABC pivotal
+Added: breast cancer study had surpassed 230 patients.
and Bria-OTS+
18 unchanged sentences
following 2 months of therapy and confirmed at 4, 6, and 11 months of therapy 1 (axial and coronal views)
−Removed: 18, 2026, the Company and BriaPro Therapeutics Corp.
−Removed: (“ BriaPro ”), a announced that we have entered into a definitive
−Removed: purchase agreement (the “ Purchase Agreement ”) pursuant to which BriaPro has agreed to purchase BriaCell’s exclusive
−Removed: license to develop and commercialize Soluble CD80 (“ sCD80 ”) as a biologic agent for the treatment of cancer and other
−Removed: associated assets (the “ Transaction ”).
−Removed: BriaCell originally secured
−Removed: the exclusive license from the University of Maryland, Baltimore County (“ UMBC ”) on August 2, 2022.
−Removed: technology, originally developed by Suzanne Ostrand-Rosenberg, Ph.D., Emeritus Faculty at UMBC, and member of BriaCell’s scientific
−Removed: advisory board, is titled “Soluble CD80 as a Therapeutic to Reverse Immune Suppression in Cancer Patients” and is covered
−Removed: under USPN 8,956,619 B2, USPN 9,650,429 B2, and USPN 10,377,810 B2.
+Added: On April 21, 2026, BriaCell presented positive data
+Added: from its preclinical Bria-OTS+ platform at the 2026 AACR meeting showing that Bria-OTS+ platform provided early, potent and durable activation
+Added: of innate and adaptive immunity in in-vitro cancer cell line models.
+Added: Additionally, our data showed immune cells activated by Bria-OTS+
+Added: exhibited serial killing activity across multiple rounds of tumor cell challenge.
+Added: On May 6, 2026, BriaCell announced that it has received
+Added: FDA clearance initiate clinical evaluation of Bria-BRES+™ in advanced metastatic breast cancer.
+Added: The IND application opens the path
+Added: to commence Phase 1/2a clinical study for Bria-BRES+ in metastatic breast cancer.
+Added: Bria-BRES+ is BriaCell’s next generation personalized
+Added: immunotherapy for breast cancer, and features additional immune activating components designed to enhance clinical efficacy.
+Added: has prepared clinical supplies of Bria-BRES+ and plans to initiate a Phase 1/2a clinical study in metastatic breast cancer in the coming
+Added: On May 14, 2026, BriaCell announced that it has completed
+Added: manufacturing clinical supplies of Bria-PROS+, its next generation, personalized, off-the-shelf, cell-based immunotherapy candidate for
+Added: prostate cancer.
+Added: On May 15 th , 2026, BriaCell announced that it is making progress in developing Bria-OVA+, its next generation,
+Added: personalized, off-the-shelf, cell-based immunotherapy for ovarian cancer.
+Added: February 18, 2026, the Company and BriaPro Therapeutics Corp.
+Added: (“ BriaPro ”), a announced that we have entered into a
+Added: definitive purchase agreement (the “ Purchase Agreement ”) pursuant to which BriaPro has agreed to purchase BriaCell’s
+Added: exclusive license to develop and commercialize Soluble CD80 (“ sCD80 ”) as a biologic agent for the treatment of cancer
+Added: and other associated assets (the “ Transaction ”).
+Added: originally secured the exclusive license from the University of Maryland, Baltimore County (“ UMBC ”) on August 2, 2022.
+Added: The novel technology, originally developed by Suzanne Ostrand-Rosenberg, Ph.D., Emeritus Faculty at UMBC, and member of BriaCell’s
+Added: scientific advisory board, is titled “Soluble CD80 as a Therapeutic to Reverse Immune Suppression in Cancer Patients” and
+Added: is covered under USPN 8,956,619 B2, USPN 9,650,429 B2, and USPN 10,377,810 B2.
In animal models, sCD80 was well-tolerated and stopped
1 unchanged sentence
and Samuel T Haile et al.
−Removed: collaboration with Dr.
+Added: in collaboration
Ostrand-Rosenberg).
−Removed: Additionally, strong anti-tumor activity of sCD80 has been reported in multiple tumor types
−Removed: (see Lucas A Horn, et al.).
−Removed: Importantly, as demonstrated in the same studies, sCD80’s unique actions may involve both awakening
−Removed: and boosting the immune system to recognize and destroy tumor cells.
−Removed: The Transaction
−Removed: terms of the Purchase Agreement, BriaPro gains the worldwide rights to develop and commercialize sCD80 as a therapeutic agent for the
−Removed: treatment of cancer, while UMBC holds all rights, title and interest in the inventions and the patent, except for certain rights retained
−Removed: by the United States Government.
−Removed: BriaPro will pay 2% royalties to UMBC upon the commercialization of the product plus other development
−Removed: As part of the Transaction,
−Removed: BriaCell will make available to BriaPro up to $3 million to fund research and development efforts (the “ Credit Facility ”).
+Added: Additionally, strong anti-tumor activity of sCD80 has been reported in multiple tumor types (see Lucas A
+Added: Horn, et al.).
+Added: Importantly, as demonstrated in the same studies, sCD80’s unique actions may involve both awakening and boosting
+Added: the immune system to recognize and destroy tumor cells.
+Added: the terms of the Purchase Agreement, BriaPro gains the worldwide rights to develop and commercialize sCD80 as a therapeutic agent for
+Added: the treatment of cancer, while UMBC holds all rights, title and interest in the inventions and the patent, except for certain rights
+Added: retained by the United States Government.
+Added: BriaPro will pay 2% royalties to UMBC upon the commercialization of the product plus other
+Added: development costs.
+Added: part of the Transaction, BriaCell will make available to BriaPro up to $3 million to fund research and development efforts (the “ Credit
Each drawdown under the Credit Facility will be subject to BriaCell’s approval regarding the use of funds.
−Removed: As consideration
−Removed: for the transfer of the exclusive license and the Credit Facility, BriaPro will issue to BriaCell 23,972,589 Common Shares at an aggregate
−Removed: value of approximately C$1.18M, increasing BriaCell’s interest in BriaPro to approximately 78% post-transaction.
−Removed: The Transaction
−Removed: is expected to close by the end of March 2026, subject to certain conditions including (i) approval of the disinterested
−Removed: shareholders of BriaPro, and (ii) receipt of a third-party valuation confirming that the Transaction is occurring at fair market
−Removed: Shareholder Approval
−Removed: In accordance
−Removed: with Multilateral Instrument 61-101 – Protection of Minority Security Holders in Special Transactions (“ MI
−Removed: 61-101 ”), the resolution approving the Purchase Agreement must be approved by a simple majority of votes cast by shareholders,
−Removed: present in person or represented by proxy and entitled to vote at the Meeting, excluding the votes cast by any “interested party”
−Removed: (as defined in MI 61-101).
−Removed: As a 10% shareholder with an interest in the Transaction, BriaCell's shareholdings in BriaPro will be excluded
−Removed: Formal Valuation Requirements
−Removed: of the formal valuation requirement of MI 61-101, BriaPro intends to rely on the specified markets exemptions set forth in subsection
−Removed: 5.5(b) of MI 61-101, as none of its securities are listed or quoted on a specified senior exchange.
−Removed: formal valuation is not required under applicable securities laws, as a matter of good governance and best corporate practice, BriaPro
−Removed: intends to obtain a valuation from an independent third-party valuator as a condition to closing, verifying and validating that Transaction
−Removed: is occurring at fair market value.
−Removed: On March 5, 2026, the disinterested shareholders of BriaPro approved the Transaction.
−Removed: of Operations for the Three and Six Months Ended January 31, 2026, and 2025
−Removed: Three months ended January 31,
+Added: consideration for the transfer of the exclusive license and the Credit Facility, BriaPro will issue to BriaCell 23,972,589 Common Shares
+Added: at an aggregate value of approximately C$1.18M, increasing BriaCell’s interest in BriaPro to approximately 78% post-transaction.
+Added: On March 5, 2026, the disinterested shareholders of BriaPro approved the Transaction and the Transaction closed on March 31, 2026.
+Added: of Operations for the Three and Nine Months Ended April 30, 2026, and 2025
+Added: Three months ended April 30,
Operating expenses:
3 unchanged sentences
Operating loss
−Removed: Financial income, net
+Added: Financial income (expense), net
Change in fair value of the warrant liability
+Added: Unrealized gain on investment
Share of loss on equity investment
Net loss for the period
+Added: $ (7,237,055 )
+Added: $ (6,224,929 )
Net loss attributable to non-controlling interest
6 unchanged sentences
following is a breakdown of our research and development costs by nature of expenses:
−Removed: months ended January 31,
−Removed: Clinical trial
−Removed: sites and investigational drug costs
+Added: Three months ended April 30,
+Added: Clinical trial sites and investigational drug costs
Wages and salaries
1 unchanged sentence
Professional fees
−Removed: the three-month period ended January 31, 2026, total research and development expenses were $6,053,689, compared to $5,684,777 for
−Removed: the three-month period ended January 31, 2025.
−Removed: Clinical trial sites and investigational drug costs decreased modestly year over
−Removed: year, primarily reflecting decreased reliance of third-party vendors in our trials as we expand our in-house headcount to advance
−Removed: our trials, which also explains the increase in wages and salaries as detailed below.
−Removed: The increase in total research and development
−Removed: expenses was primarily driven by wages and salaries, which rose from $1,292,021 in 2025 to $1,881,893 in 2026, reflecting higher
−Removed: headcount and additional personnel required to support clinical operations and ongoing development programs.
−Removed: Laboratory rent
−Removed: increased to $130,500 in 2026, compared to $114,330 in 2025, due to expanded utilization of laboratory space and related facility
−Removed: Supplies increased from $85,264 in 2025 to $134,974 in 2026, reflecting increased consumable usage driven by greater
−Removed: clinical and laboratory activity during the current period.
−Removed: Depreciation expense was consistent year over year at $22,839 for both
−Removed: Professional fees increased from $1,908 in 2025 to $4,944 in 2026, primarily due to higher consulting, regulatory, and
−Removed: scientific support related to advancing clinical development.
−Removed: Share-based compensation increased from $50,839 in 2025 to $79,016 in
−Removed: 2026, reflecting a higher level of equity-based awards outstanding during the period.
+Added: Share-based compensation
+Added: the three-month period ended April 30, 2026, total research and development expenses were $5, 966,673 ,
+Added: compared to $4,810,196 for the three-month period ended April 30, 2025.
+Added: The increase was primarily driven by higher clinical trial
+Added: sites and investigational drug costs, which increased to $3, 980,115 in
+Added: 2026 from $3,175,543 in 2025, reflecting expanded clinical development activities.
+Added: Wages and salaries also increased to $1, 492,067
+Added: from $1,303,157, due to higher personnel costs supporting ongoing research programs.
+Added: Laboratory rent increased to $130,500 from
+Added: $114,330, while depreciation expense increased to $29,193 from $22,839.
+Added: Share-based compensation increased significantly to $175,999
+Added: in 2026 from $36,493 in 2025, reflecting a higher level of equity-based awards granted during the period.
clinical trial expenses are broken down as follows:
−Removed: months ended January 31,
−Removed: Pivotal Phase 3 study
+Added: Three months ended April 30,
+Added: Bria-IMT™ Pivotal Phase 3 study
Bria-IMT™ Phase 1/2a
−Removed: trial expenses for the three months ended January 31, 2026, were $5,008,171, compared to $3,923,559 during the same period in 2025.
+Added: Bria-OTS™ Phase 1/2a
+Added: trial expenses for the three months ended April 30, 2026, were $4,349,651, compared to $3,190,751 during the same period in 2025.
increase reflects continued investment in the Bria-IMT™ pivotal Phase 3 program and ongoing advancement of the Bria-OTS™
2 unchanged sentences
increase in clinical trial expenses.
−Removed: For the three-month
−Removed: period ended January 31, 2026, Bria-IMT™ Pivotal Phase 3 Study costs were $3,874,242, compared to $3,642,650 in 2025.
−Removed: reflects the study’s continued progression through an advanced, cost-intensive stage, including expanded patient enrollment, increased
−Removed: clinical site activity, CRO services, central laboratory work, and clinical supply management.
−Removed: The level of spending is consistent with
−Removed: maintaining study momentum as the program advances toward planned interim analyses.
−Removed: the three-month period ended January 31, 2026, Bria-IMT™ Phase 1/2a expenses were $197,203, compared to $215,301 in 2025.
+Added: the three-month period ended April 30, 2026, Bria-IMT™ Pivotal Phase 3 Study costs were $3,149,348, compared to $2,708,394 in 2025.
+Added: The increase reflects the study’s continued progression through an advanced, cost-intensive stage, including expanded patient enrollment,
+Added: increased clinical site activity, CRO services, central laboratory work, and clinical supply management.
+Added: The level of spending is consistent
+Added: with maintaining study momentum as the program advances toward planned interim analyses.
+Added: the three-month period ended April 30, 2026, Bria-IMT™ Phase 1/2a expenses were $159,579, compared to $300,013 in 2025.
reflects the continued wind-down of the program following completion of primary activities in fiscal 2024, with current-period costs
2 unchanged sentences
modest as final wrap-up items are completed.
−Removed: the three-month period ended January 31, 2026, Bria-OTS™ Phase 1/2a expenses were $936,726, compared to $65,608 in 2025.
+Added: the three-month period ended April 30, 2026, Bria-OTS™ Phase 1/2a expenses were $1,040,724, compared to $182,344 in 2025.
The substantial
6 unchanged sentences
and Administrative Expenses
−Removed: the three-month period ended January 31, 2026, general and administrative expenses were $1,477,577, compared to $1,484,666 for the same
−Removed: period in 2025.
−Removed: The decrease was primarily driven by lower share-based compensation, professional fees, consulting, shareholder communications,
−Removed: and travel expenses, partially offset by higher wages and salaries, regulatory, filing and transfer agent fees, insurance, and other
−Removed: general administrative costs.
−Removed: For the three-month period ended January 31, 2026, the Company recorded
−Removed: net financial income of $84,589, compared to $67,358 in the same period of 2025.
−Removed: The increase is mainly attributable to higher foreign
−Removed: exchange losses offset by higher interest income.
−Removed: For the three-month period ended January 31, 2026, financial income was comprised of
−Removed: $105,638 of interest income, and a $21,049 foreign exchange loss.
+Added: the three-month period ended April 30, 2026, general and administrative expenses were $1,654,121, compared to $1,518,059 for the three-month
+Added: period ended April 30, 2025.
+Added: The increase was primarily attributable to higher shareholder communications expense, which increased from
+Added: $146,616 in 2025 to $307,058 in 2026, higher share-based compensation of $256,208 in 2026 compared to $188,322 in 2025, increased consulting
+Added: expenses from $44,222 in 2025 to $98,621 in 2026, and higher wages and salaries, which increased from $325,926 in 2025 to $359,873 in
+Added: These increases were partially offset by lower professional fees, insurance expense, regulatory, filing and transfer agent fees,
+Added: and travel expenses.
+Added: the three-month period ended April 30, 2026, the Company recorded net financial income of $186,970, compared to net financial expense
+Added: of $9,762 in the same period of 2025.
+Added: The increase is mainly attributable to higher interest income and lower interest expense.
+Added: three-month period ended April 30, 2026, financial income was comprised of $219,220 of interest income, $29,631 of interest expense and
+Added: $2,619 foreign exchange loss.
(loss) for the period
−Removed: For the three-month period ended January 31, 2026, the Company reported
−Removed: a net loss of $7,296,893, compared to $6,337,828 for the same period in 2025.
−Removed: The higher loss primarily reflects higher operating expenses,
−Removed: including increased research and development spending as the Company continued to advance its pivotal Phase 3 trial, including higher
−Removed: clinical-site activity, investigational product costs, and supporting operational infrastructure.
−Removed: of Operations for the Six Months Ended January 31, 2026 and 2025
−Removed: Six months ended January 31,
+Added: the three-month period ended April 30, 2026, the Company reported a net loss of $7,237,055, compared to $6,224,929 for the same period
+Added: The higher loss primarily reflects higher operating expenses, including increased research and development spending as the Company
+Added: continued to advance its pivotal Phase 3 trial, including higher clinical-site activity, investigational product costs, and supporting
+Added: operational infrastructure.
+Added: of Operations for the Nine Months Ended April 30, 2026 and 2025
+Added: Nine months ended April 30,
Operating Expenses:
3 unchanged sentences
Operating loss
+Added: (23,475,003 )
+Added: (18,650,530 )
Financial income, net
Change in fair value of the warrant liability
+Added: Unrealized gain on investment
Share of loss on equity investments
Net loss for the period
+Added: $ (22,812,276 )
+Added: (18,392,033 )
Net loss attributable to non-controlling interest
Net loss for the period attributable to BriaCell
+Added: (22,583,892 )
+Added: (18,220,497 )
Net loss per share attributable to BriaCell – basic and diluted
−Removed: Weighted average number of shares used in computing net basic earnings per share of common stock
−Removed: Weighted average number of shares used in computing net diluted earnings per share of common stock
+Added: Weighted average number of shares used in computing net basic and diluted earnings per share of common stock
Development, and Clinical Trial Costs
3 unchanged sentences
following is a breakdown of our research, development, and clinical trial costs by nature of expenses:
−Removed: months ended January 31,
−Removed: Clinical trial
−Removed: sites and Investigational drug costs
+Added: Nine months ended April 30,
+Added: Clinical trial sites and Investigational drug costs
Wages and salaries
1 unchanged sentence
Professional fees
−Removed: the six-month period ended January 31, 2026, research, development, and clinical trial expenses were $12,737,332, compared to $9,350,118
+Added: Share-based compensation
+Added: the nine-month period ended April 30, 2026, research, development, and clinical trial expenses were $18,704,005, compared to $14,160,314
for the same period in 2025.
−Removed: The increase was primarily driven by higher clinical trial site and investigational drug costs, which rose
−Removed: from $6,557,243 in 2025 to $8,662,722 in 2026 as the Company advanced its clinical programs.
−Removed: Wages and salaries increased from $2,241,110
−Removed: in 2025 to $3,185,595 in 2026, reflecting increased headcount and personnel supporting clinical and development activities.
−Removed: rent increased to $255,110 in 2026 from $228,660 in 2025 due to expanded use of facilities.
−Removed: Supplies increased to $411,631 in 2026 from
−Removed: $184,694 in 2025, reflecting higher clinical and laboratory activity.
−Removed: Depreciation expense remained consistent year over year at $45,678.
−Removed: Professional fees increased to $14,149 in 2026 from $9,176 in 2025 due to increased consulting and support for clinical operations.
−Removed: compensation increased to $162,447 in 2026 from $83,557 in 2025, reflecting a higher level of equity-based awards outstanding during
+Added: The increase was primarily driven by higher clinical trial sites and investigational drug costs, which increased
+Added: from $9,732,786 in 2025 to $12,642,837 in 2026, reflecting the advancement of the Company’s clinical development programs.
+Added: and salaries increased from $3,544,267 in 2025 to $4,677,662 in 2026, due to increased headcount and personnel supporting clinical and
+Added: development activities.
+Added: Laboratory rent increased from $342,990 in 2025 to $385,610 in 2026, while supplies increased from $341,878 in
+Added: 2025 to $568,727 in 2026, reflecting higher clinical and laboratory activity.
+Added: Share-based compensation increased from $120,050 in 2025
+Added: to $338,446 in 2026, reflecting a higher level of equity-based awards outstanding during the period.
trial expenses for the period are as follows:
−Removed: months ended January 31,
−Removed: Pivotal Phase 3 study
+Added: Nine months ended April 30,
+Added: Bria-IMT™ Pivotal Phase 3 study
Bria-IMT™ Phase 1/2a
−Removed: trial expenses for the six months ended January 31, 2026, were $9,952,363, compared to $6,631,649 during the same period in 2025.
+Added: Bria-OTS™ Phase 1/2a
+Added: trial expenses for the nine months ended April 30, 2026, were $14,302,014, compared to $9,822,400 during the same period in 2025.
increase reflects sustained investment in the Bria-IMT™ pivotal Phase 3 program and significant advancement of the Bria-OTS™
2 unchanged sentences
increase in clinical trial expenses.
−Removed: the six-month period ended January 31, 2026, Bria-IMT™ Pivotal Phase 3 Study costs were $7,667,192, compared to $6,089,111 in 2025.
+Added: the nine-month period ended April 30, 2026, Bria-IMT™ Pivotal Phase 3 Study costs were $10,816,541, compared to $8,797,505 in 2025.
The increase reflects continued patient enrollment, expansion of clinical sites, increased clinical site activity, CRO services, central
2 unchanged sentences
the period are consistent with maintaining operational momentum as the trial advances toward planned interim analyses.
−Removed: For the six-month period ended
−Removed: January 31, 2026, Bria-IMT™ Phase 1/2a expenses were $360,407, compared to $399,343 in 2025.
−Removed: The decrease reflects the continued
−Removed: wind-down of the program following completion of primary activities in fiscal 2024.
−Removed: Current-period costs primarily relate to residual
−Removed: close-out procedures, data management, and limited follow-up activities.
−Removed: Expenses are expected to decline further as final wrap-up activities
−Removed: For the six-month
−Removed: period ended January 31, 2026, Bria-OTS™ Phase 1/2a expenses were $1,924,764, compared to $143,195 in 2025.
−Removed: The substantial increase
−Removed: reflects continued advancement of the OTS program into early clinical development.
−Removed: Costs incurred during the period include expanded
−Removed: development and manufacturing activities, GMP production of Bria-BRES+ and Bria-PROS+, regulatory and analytical support, and operational
−Removed: activities necessary to support ongoing evaluation of the next-generation Bria-OTS+ platform.
−Removed: The increased investment aligns with the
−Removed: program’s progression and expansion across multiple solid tumor indications.
+Added: the nine-month period ended April 30, 2026, Bria-IMT™ Phase 1/2a expenses were $519,986, compared to $699,356 in 2025.
+Added: reflects the continued wind-down of the program following completion of primary activities in fiscal 2024.
+Added: Current-period costs primarily
+Added: relate to residual close-out procedures, data management, and limited follow-up activities.
+Added: Expenses are expected to decline further
+Added: as final wrap-up activities conclude.
+Added: the nine-month period ended April 30, 2026, Bria-OTS™ Phase 1/2a expenses were $2,965,488, compared to $325,539 in 2025.
+Added: The substantial
+Added: increase reflects continued advancement of the OTS program into early clinical development.
+Added: Costs incurred during the period include
+Added: expanded development and manufacturing activities, GMP production of Bria-BRES+ and Bria-PROS+, regulatory and analytical support, and
+Added: operational activities necessary to support ongoing evaluation of the next-generation Bria-OTS+ platform.
+Added: The increased investment aligns
+Added: with the program’s progression and expansion across multiple solid tumor indications.
and Administrative Expenses
−Removed: For the six-month period ended January 31, 2026, general and administrative expenses amounted to $3,116,877, compared
−Removed: to $2,972,157 for the same period in 2025.
−Removed: The increase was primarily driven by higher wages and salaries, regulatory and filing fees,
−Removed: insurance, and other administrative costs, partially offset by lower consulting, professional fees, and travel expenses.
−Removed: For the six-month period ended January 31, 2026, financial income amounted
−Removed: to $243,235, compared to $79,072 for the six-month period ended January 31, 2025.
−Removed: Financial income for the 2026 period consisted of $243,607
−Removed: in interest income and a $372 foreign exchange loss.
−Removed: In comparison, financial income for the 2025 period included $59,882 in interest
−Removed: income and a $19,190 foreign exchange gain.
−Removed: The increase in financial income from 2025 to 2026 was primarily due to higher interest income,
−Removed: reflecting increased cash and cash equivalents available for investment in interest-bearing funds.
−Removed: for the period
−Removed: The Company reported a loss of $15,575,221 for the six-month period
−Removed: ended January 31, 2026, compared to $12,167,104 for the same period in 2025.
−Removed: The increase in loss was primarily driven by higher research,
−Removed: development and clinical trial expenses, which rose to $12,737,332 in 2026 from $9,350,118 in 2025 as the Company advanced its clinical
−Removed: This was partially offset by higher financial income in the current period, including increased interest income and a lower
+Added: the nine-month period ended April 30, 2026, general and administrative expenses amounted to $4,770,998, compared to $4,490,216 for the
+Added: same period in 2025.
+Added: The increase was primarily driven by higher shareholder communications expenses, which increased from $425,804 in
+Added: 2025 to $860,951 in 2026, as well as higher wages and salaries, which increased from $951,371 in 2025 to $1,228,753 in 2026.
+Added: These increases
+Added: were partially offset by lower professional fees, which decreased from $875,632 in 2025 to $667,463 in 2026, and lower travel expenses,
+Added: which decreased from $265,617 in 2025 to $106,439 in 2026.
+Added: the nine-month period ended April 30, 2026, financial income amounted to $430,205, compared to $69,310 for the nine-month period ended
+Added: April 30, 2025.
+Added: Financial income for the 2026 period consisted of $462,827 in interest income, an interest expense of $29,631 and a $2,991
foreign exchange loss.
+Added: In comparison, financial income for the 2025 period included $86,514 in interest income, an interest expense of
+Added: $36,979 and a $19,775 foreign exchange gain.
+Added: The increase in financial income from 2025 to 2026 was primarily due to higher interest
+Added: income, reflecting increased cash and cash equivalents available for investment in interest-bearing funds.
+Added: for the period
+Added: Company reported a loss of $22,812,276 for the nine-month period ended April 30, 2026, compared to $18,392,033 for the same period in
+Added: The increase in loss was primarily driven by higher research, development and clinical trial expenses, which rose to $18,704,005
+Added: in 2026 from $14,160,314 in 2025 as the Company advanced its clinical programs.
Capital Resources and Going Concern Uncertainty
−Removed: financial statements have been prepared on a going concern basis, which assumes that the Company will be able to realize its assets and
−Removed: discharge its liabilities in the normal course of business for the foreseeable future.
−Removed: The continuing operations of the Company are dependent
−Removed: upon its ability to continue to raise adequate financing and to commence profitable operations in the future.
−Removed: As of January 31, 2026, the company had a positive working capital
−Removed: balance of $28,993,334 (July 31, 2025 positive balance of $15,948,588).
−Removed: As of January 31, 2026, the Company has total assets of $33,594,454
−Removed: (July 31, 2025 - $ 21,649,706), a positive working capital of $28,993,334 (July 31, 2025 – positive balance of $15,948,588) and
−Removed: an accumulated deficit of $127,174,949 (July 31, 2025 - negative balance of $ 111,755,564).
−Removed: of January 31, 2026, the Company’s capital resources consist primarily of cash and cash equivalents, comprising mostly
+Added: of April 30, 2026, the company had a positive working capital balance of $21,802,678 (July 31, 2025 positive balance of $15,948,588).
+Added: of April 30, 2026, the Company has total assets of $27,071,310 (July 31, 2025 - $ 21,649,706), working capital of $21,802,678
+Added: (July 31, 2025 – positive balance of $15,948,588) and an accumulated deficit of $134,339,456 (July 31, 2025 - $111,755,564).
+Added: of April 30, 2026, the Company’s capital resources consist primarily of cash and cash equivalents, comprising mostly
of cash on deposit with banks, investments in money market funds, investments in U.S.
4 unchanged sentences
on preservation of capital and supporting our liquidity requirements.
−Removed: Historically,
−Removed: the Company has financed its operation through private and public placement of equity securities, as well as debt financing.
−Removed: The Company’s
−Removed: ability to fund its longer-term cash requirements is subject to multiple risks, many of which are beyond its control.
−Removed: The Company intends
−Removed: to raise additional capital, either through debt or equity financings in order to achieve its business plan objectives.
−Removed: Management believes
−Removed: that it can be successful in obtaining additional capital;
−Removed: however, there can be no assurance that the Company will be able to do so.
−Removed: There is no assurance that any funds raised will be sufficient to enable the Company to attain profitable operations or continue as a
−Removed: going concern.
−Removed: To the extent that the Company is unsuccessful, the Company may need to curtail or cease its operations and implement
−Removed: a plan to extend payables or reduce overhead until sufficient additional capital is raised to support further operations.
−Removed: no assurance that such a plan will be successful.
−Removed: To this end, for several months during calendar year 2025, certain directors and officers
−Removed: agreed to defer payment of their directors’ fees/compensation until we completed a financing, after which, these fees were paid
−Removed: Further, certain officers have indicated their willingness to receive a portion of their compensation in equity of the Company,
−Removed: subject to applicable Nasdaq rules.
−Removed: In addition, we continue to reduce expenditure on certain non-core activities whilst maintaining
−Removed: our focus on our Phase 3 Bria-IMT™ pivotal study in advanced metastatic breast cancer.
−Removed: During the period ended January 31, 2026, the Company’s overall
−Removed: position of cash and cash equivalents increased by $19,409,820 from the period ended July 31, 2025 (including effects of foreign exchange).
−Removed: This increase in cash can be attributed to the following:
−Removed: The Company’s net cash used in operating activities during the
−Removed: period ended January 31, 2026, was $15,672,094 as compared to $12,875,298 for the period ended January 31, 2025.
−Removed: gained in financing activities for the period ended January 31, 2026, was 27,874,441 as compared to 17,176,863 for the period ended January
+Added: The Company continues to devote substantially all of its efforts toward research and development activities.
+Added: course of such activities, the Company has sustained operating losses and expects such losses to continue in the foreseeable future.
+Added: Company’s accumulated deficit as of April 30, 2026 was $134,339,456 and negative cash flows from operating activities during the
+Added: nine-month period ended April 30, 2026 was $22,692,452.
+Added: The Company is planning to finance its operations by exploring additional sources
+Added: of capital and financing, while managing its existing working capital resources.
+Added: During the year ended July 31, 2025, the Company raised
+Added: $50.9 million in gross proceeds from equity financings and, in January 2026, completed a public offering generating approximately $30
+Added: million in gross proceeds.
+Added: However, the Company’s ability to continue as a going concern is dependent upon its ability to attain
+Added: future profitable operations and to continue to obtain the necessary financing to meet its obligations arising from normal business operations
+Added: when they come due.
+Added: The uncertainty of the Company’s ability to raise such financial capital casts substantial doubt on the Company’s
+Added: ability to continue as a going concern.
+Added: These condensed consolidated financial statements do not include any adjustments to the amounts
+Added: and classification of assets and liabilities that might be necessary should the Company not be able to continue as a going concern.
+Added: the period ended April 30, 2026, the Company’s overall position of cash and cash equivalents decreased by $3,613,587 from the
+Added: period ended July 31, 2025 (including effects of foreign exchange).
+Added: This decrease in cash can
+Added: be attributed to the following:
+Added: Company’s net cash used in operating activities during the nine-month period ended April 30, 2026, was $22,692,452 as compared
+Added: to $20,038,075 for the nine-month period ended April 30, 2025.
+Added: Net cash used in investing activities
+Added: during the nine-month period ended April 30, 2026, was $8,795,576 as compared to $225,000 for the nine-month period ended April 30, 2025.
+Added: During 2026, this was primarily from the net purchase of short-term investments.
+Added: gained in financing activities for the nine-month period ended April 30, 2026, was 27,874,441 as compared to 31,891,239 for the
+Added: nine-month period ended April 30, 2025.
+Added: During both periods, this was primarily from the proceeds of the issuance of shares in various financings.
Sheet Arrangements
4 unchanged sentences
Accounting Policies Adopted
−Removed: Company did not adopt any new accounting policies during the period ended January 31, 2026.
+Added: Company did not adopt any new accounting policies during the period ended April 30, 2026.
Compared sentence by sentence after normalising whitespace, quotation marks, case and digits, so re-formatting and restated figures do not read as changed language. Wording changes appear as one removal and one addition. The current filing and the prior one are authoritative.