FINANCIAL STATEMENTS
−Removed: Unicycive Therapeutics, Inc.
+Added: Unicycive Therapeutics,
Balance Sheets
(In thousands, except for share and per share
−Removed: September 30,
Current assets:
1 unchanged sentence
Prepaid expenses and other current assets
+Added: Marketable securities
Total current assets
8 unchanged sentences
Total current liabilities
−Removed: Operating lease liability – long term
+Added: Operating lease liability – long
Total liabilities
1 unchanged sentence
Stockholders’ equity:
−Removed: Series A-2 Prime preferred stock, $ 0.001 par value per share – 21,400 Series A-2 Prime shares authorized at December 31, 2024, and September 30, 2025;
−Removed: 6,150.21 and 2,265 Series A-2 Prime shares issued and outstanding at December 31, 2024, and September 30, 2025, respectively
−Removed: Series B-2 preferred stock, $ 0.001 par value per share – 50,000 Series B-2 shares authorized at December 31, 2024, and September 30, 2025;
−Removed: 3,000 and zero Series B-2 shares issued and outstanding at December 31, 2024, and September 30, 2025, respectively
−Removed: Preferred stock, $ 0.001 par value per share— 10,000,000 shares authorized at December 31, 2024, and September 30, 2025;
−Removed: zero shares issued and outstanding at December 31, 2024, and September 30, 2025
−Removed: Common stock, $ 0.001 par value per share – 400,000,000 shares
−Removed: authorized at December 31, 2024, and September 30, 2025;
−Removed: 11,384,236 and 20,850,363 shares issued and outstanding at December 31, 2024,
−Removed: and September 30, 2025, respectively
+Added: Series A-2 Prime preferred stock, $ 0.001 par value per share – 21,388.01 Series A-2 Prime shares authorized at December 31, 2025, and March 31, 2026;
+Added: 2,265 Series A-2 Prime shares issued and outstanding at December 31, 2025, and March 31, 2026
+Added: Series B-2 preferred stock, $ 0.001 par value per share – 50,000 Series B-2 shares authorized at December 31, 2025, and March 31, 2026;
+Added: zero Series B-2 shares issued and outstanding at December 31, 2025, and March 31, 2026
+Added: Preferred stock, $ 0.001 par value per share— 10,000,000 shares authorized at December 31, 2025, and March 31, 2026;
+Added: zero shares issued and outstanding at December 31, 2025, and March 31, 2026
+Added: Common stock, $ 0.001 par value per share – 400,000,000 shares authorized at December 31, 2025, and March 31, 2026;
+Added: 22,114,245 and 25,237,782 shares issued and outstanding at December 31, 2025, and March 31, 2026, respectively
+Added: Accumulated other comprehensive (loss) income
Additional paid-in capital
1 unchanged sentence
Total stockholders’ equity
−Removed: Total liabilities and stockholders’ equity
+Added: Total liabilities and stockholders’
See accompanying notes to the financial statements
−Removed: Unicycive Therapeutics, Inc.
−Removed: Statements of Operations
+Added: Unicycive Therapeutics,
+Added: Statements of Operations and Comprehensive
+Added: Income (Loss)
(In thousands, except for share and per share
Three Months Ended
−Removed: September 30,
−Removed: Nine months ended
−Removed: September 30,
+Added: Three Months Ended
Operating expenses:
8 unchanged sentences
Total other income (expenses)
−Removed: Dividend to Series B-1 preferred stockholders
−Removed: Net loss attributable to common stockholders
−Removed: Net loss per share attributable to common stockholders, basic and diluted
−Removed: Weighted-average shares outstanding used in computing net loss per share, basic and diluted
+Added: Net income (loss)
+Added: Other comprehensive loss:
+Added: Unrealized loss on marketable securities,
+Added: Net comprehensive income (loss)
+Added: Net comprehensive income (loss) attributable
+Added: to common stockholders, basic
+Added: Net comprehensive loss attributable to
+Added: common stockholders, diluted
+Added: Net comprehensive income (loss) per share
+Added: Weighted-average shares outstanding used in computing net comprehensive
+Added: income (loss) per share:
See accompanying notes to the financial statements
−Removed: Unicycive Therapeutics, Inc.
−Removed: Statements of Mezzanine Equity and Stockholders’
+Added: Unicycive Therapeutics,
+Added: Statements of Stockholders’ Equity
(In thousands, except share amounts)
−Removed: Preferred Stock
−Removed: Stockholders’
−Removed: at December 31, 2023
−Removed: of Series B-1 preferred stock, net of issuance costs
−Removed: on Series B-1 preferred stock
−Removed: of Series A-2 preferred stock for Series A-2 Prime preferred stock
−Removed: of Series A-2 Prime preferred stock into common stock
−Removed: of common stock for exercise of options
−Removed: compensation expense
−Removed: at March 31, 2024
−Removed: Paid on Series B-1 preferred stock
−Removed: of Series A-2 Prime preferred stock into common stock
−Removed: of common stock for exercise of options
−Removed: compensation expense
−Removed: at June 30, 2024
−Removed: of Series A-2 Prime preferred stock into common stock
−Removed: of Series B-2 preferred stock and common stock upon conversion of Series B-1 preferred stock
−Removed: of common stock for exercise of options
−Removed: compensation expense
−Removed: at September 30, 2024
+Added: Series A-2 Prime
Preferred Stock
Preferred Stock
−Removed: at December 31, 2024
+Added: Stockholder’s
+Added: Balance at December 31, 2024
$ ( 101,270 )
−Removed: of Series A-2 Prime preferred stock into common stock
−Removed: of common stock for cash, net of issuance costs
−Removed: compensation expense
−Removed: at March 31, 2025
+Added: Conversion of Series A-2 Prime preferred stock into common
+Added: Issuance of common stock for cash, net of issuance costs
+Added: Stock-based compensation expense
+Added: Balance at March 31, 2025
$ ( 100,700 )
−Removed: of Series A-3 preferred stock upon exercise of warrants
−Removed: of Series B-2 preferred stock into common stock
−Removed: of Series A-3 preferred stock into common stock
−Removed: of common stock for vested restricted stock units
−Removed: of common stock for cash, net of issuance costs
−Removed: compensation expense
−Removed: at June 30, 2025
+Added: Series A-2 Prime
+Added: Preferred Stock
+Added: Comprehensive
+Added: Stockholders’
+Added: Income (Loss)
+Added: Balance at December 31, 2025
$ ( 127,825 )
−Removed: of Series A-2 Prime preferred stock into common stock
−Removed: of common stock for vested restricted stock units
−Removed: of common stock for cash, net of issuance costs
−Removed: Reverse split share adjustment
−Removed: compensation expense
−Removed: at September 30, 2025
+Added: Issuance of common stock for cash, net of issuance costs
+Added: Unrealized gain on available-for-sale securities, net
+Added: Stock-based compensation expense
+Added: Balance at March 31, 2026
$ ( 140,648 )
See accompanying notes to the financial statements
−Removed: Unicycive Therapeutics, Inc.
+Added: Unicycive Therapeutics,
Statements of Cash Flows
(In thousands)
−Removed: Nine months ended
−Removed: September 30,
+Added: Three Months Ended
+Added: Three Months Ended
Cash flows from operating activities
−Removed: Adjustments to reconcile net loss to net cash used in operating activities:
+Added: Net income (loss)
+Added: Adjustments to reconcile net loss to net cash used in operating
Depreciation expense
+Added: Loss on disposal of assets
Stock-based compensation expense
1 unchanged sentence
Amortization of operating lease right of use asset
+Added: Amortization of investments in marketable securities
Changes in assets and liabilities:
4 unchanged sentences
Cash flows from investing activities
+Added: Purchases of marketable securities
Purchases of property and equipment
+Added: Realized gain on marketable securities
Net cash used in investing activities
Cash flows from financing activities
−Removed: Proceeds from secondary public offering
+Added: Gross proceeds from secondary public offering
Commissions paid on secondary public offering
Payments on financed insurance policies
−Removed: Issuance costs related to issuance of Series B-1 preferred stock
−Removed: Proceeds from issuance of Series B-1 preferred stock
−Removed: Proceeds from exercise of warrants
−Removed: Dividends on preferred stock
Net cash provided by financing activities
−Removed: Net increase in cash and cash equivalents
−Removed: Cash and cash equivalents at the beginning of the period
−Removed: Cash and cash equivalents at the end of the period
+Added: Net increase (decrease) in cash and cash
+Added: Cash and cash equivalents at the beginning
+Added: of the period
+Added: Cash and cash equivalents at the end of
Supplemental cash flow information
−Removed: Issuance of Series B-2 preferred stock and common stock upon conversion of Series B-1 preferred stock
−Removed: Deferred insurance charges included in prepaid expenses and other current assets
−Removed: Deferred preclinical and other charges included in prepaid expenses and other current assets
+Added: Initial recognition of right-of-use assets and corresponding lease
+Added: Deferred insurance charges included in prepaid expenses and
+Added: other current assets
+Added: Deferred preclinical and other charges included in prepaid
+Added: expenses and other current assets
Cash paid for interest
See accompanying notes to the financial statements
−Removed: Unicycive Therapeutics, Inc.
−Removed: Notes to the Financial Statements (Unaudited)
+Added: Unicycive Therapeutics,
+Added: Notes to the Financial Statements
Organization and Description of Business
Unicycive Therapeutics, Inc.
−Removed: (“we”, “the Company”) was incorporated in the State of Delaware on August 18, 2016 .
+Added: “the Company”) was incorporated in the State of Delaware on August 18, 2016 .
The Company in-licensed the drug candidate UNI
5 unchanged sentences
drug candidate, Renazorb RZB 012 and its trademark, RENALAN, and various patents from Spectrum Pharmaceuticals, Inc.
−Removed: Renazorb (“Oxylanthanum Carbonate”) is being developed for the treatment of hyperphosphatemia in patients with Chronic
−Removed: Kidney Disease (“CKD”).
+Added: Renazorb (“oxylanthanum carbonate”) is being developed for the treatment of hyperphosphatemia in patients with
+Added: Chronic Kidney Disease (“CKD”).
The Company continues to evaluate the licensing
−Removed: of additional technologies and drugs, targeting orphan diseases and other renal, liver and other metabolic diseases affecting fibrosis
−Removed: and inflammation.
+Added: of additional technologies and drugs in order to pursue development, regulatory approval, and commercialization of those products in
+Added: global markets.
The Company is subject to risks and uncertainties
8 unchanged sentences
negative cash flows from operations since inception and expects to continue to incur negative cash flows from operations in the future.
−Removed: As the Company increases its research and development activities, the operating losses are expected to increase.
+Added: As the Company continues its drug development activities, the operating losses are expected to increase.
The Company has historically
relied on private equity offerings, debt financing and loans from a stockholder to fund its operations.
−Removed: As of December 31, 2024 and September
+Added: As of December 31, 2025 and March
31, 2026, the Company had an accumulated deficit of $ 127.8 million and $ 140.6 million, respectively.
6 unchanged sentences
other commercial planning.
−Removed: On March 3, 2023, the Company entered into a securities
−Removed: purchase agreement with certain healthcare-focused institutional investors that may provide up to $ 130.0 million in gross proceeds through
−Removed: a private placement and that included initial upfront funding of $ 28.0 million in net proceeds.
On March 3, 2023, the Company entered into a
+Added: securities purchase agreement with certain healthcare-focused institutional investors that may provide up to $ 130.0 million in gross
+Added: proceeds through a private placement and that included initial upfront funding of $ 30.0 million in gross proceeds.
+Added: On March 13, 2024, the Company entered into a
securities purchase agreement with certain healthcare-focused institutional investors to provide $ 50.0 million in gross proceeds through
a private placement.
−Removed: Pursuant to the securities purchase agreement, the Company issued institutional investors $ 50 million in shares of
−Removed: Series B Convertible Preferred Stock.
+Added: Pursuant to the securities purchase agreement, the Company issued institutional investors $ 50.0 million in shares
+Added: of Series B Convertible Preferred Stock.
The Company received $ 46.2 million in net proceeds.
−Removed: On November 13, 2024, we entered into a sales
−Removed: agreement, with Guggenheim Securities, LLC pursuant to which, we may offer and sell shares of common stock having an aggregate offering
−Removed: price of up to $ 50.0 million, subject to certain limitations and in accordance with the terms of the sales agreement, from time to time
−Removed: through or to Guggenheim Securities, LLC acting as sales agent or principal.
−Removed: During the nine months ended September 30, 2025,
−Removed: the Company sold 8,046,736 shares of common stock pursuant to a sales agreement, with Guggenheim Securities, LLC, at an average price
−Removed: of $ 4.94 per share and paid $ 1.2 million in commissions, resulting in net proceeds to the Company of approximately $ 38.6 million.
+Added: On November 13, 2024, the Company entered into
+Added: a sales agreement, with Guggenheim Securities, LLC as amended by Amendment No.
+Added: 1 thereto dated November 14, 2025 (as amended, the “Sales
+Added: Agreement”) pursuant to which, we may offer and sell shares of common stock having an aggregate offering price of up to $ 100.0
+Added: million, subject to certain limitations and in accordance with the terms of the sales agreement, from time to time through or to Guggenheim
+Added: Securities, LLC acting as sales agent or principal.
+Added: During the quarter ended March 31, 2026, the
+Added: Company sold 3,123,537 shares of common stock pursuant to a sales agreement, with Guggenheim Securities, LLC, at an average price of
+Added: $ 6.46 per share and paid $ 0.6 million in commissions, resulting in net proceeds to the Company of approximately $ 19.6 million.
The Company expects to continue incurring losses
−Removed: in the future and will be required to raise additional capital in the future to complete its planned clinical trials, pursue product development
−Removed: initiatives and penetrate markets for the sale of its products.
−Removed: Management believes that the Company will continue to have access to capital
−Removed: resources through possible equity offerings, debt financings, corporate collaborations or other means.
−Removed: There can be no assurance that
−Removed: the Company will be able to obtain additional financing on terms acceptable to the Company, on a timely basis or at all.
−Removed: If the Company
−Removed: is unable to secure additional capital, it may be required to curtail any clinical trials and development of new or existing products
−Removed: and take additional measures to reduce expenses in order to conserve its cash in amounts sufficient to sustain operations and meet its
−Removed: Based on the Company’s currently anticipated level of expenditures, the Company believes that it has sufficient resources
−Removed: such that there is not substantial doubt about the ability to continue operations for at least one year after the date that these financial
−Removed: statements are available to be issued.
+Added: in the future and will be required to raise additional capital in the future to complete its planned clinical trials, pursue product
+Added: development initiatives and penetrate markets for the sale of its products.
+Added: Management believes that the Company will continue to have
+Added: access to capital resources through possible equity offerings, debt financings, corporate collaborations or other means.
+Added: no assurance that the Company will be able to obtain additional financing on terms acceptable to the Company, on a timely basis or at
+Added: If the Company is unable to secure additional capital, it may be required to curtail any clinical trials and development of new
+Added: or existing products and take additional measures to reduce expenses in order to conserve its cash in amounts sufficient to sustain operations
+Added: and meet its obligations.
+Added: Based on the Company’s currently anticipated level of expenditures, the Company believes that it has
+Added: sufficient resources such that there is not substantial doubt about the ability to continue operations for at least one year after the
+Added: date that these financial statements are available to be issued.
Summary of Significant Accounting Policies
3 unchanged sentences
The accompanying unaudited financial statements
−Removed: of the Company as of September 30, 2025 have been prepared in accordance with the instructions to Form 10-Q and Article 10 of Regulation
−Removed: S-X and, accordingly, they do not include all information and footnote disclosures required by accounting principles generally accepted
−Removed: in the “GAAP”.
−Removed: The Company believes the footnotes and other disclosures made in the financial statements are adequate
−Removed: for a fair presentation of the results of the interim periods presented.
−Removed: The financial statements include all adjustments (solely of a
−Removed: normal recurring nature) which are, in the opinion of management, necessary to make the information presented not misleading.
−Removed: read these financial statements and the accompanying notes in conjunction with the financial statements and notes thereto included in
−Removed: the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2024, filed with the U.S.
−Removed: Securities and Exchange
−Removed: Commission on March 31, 2025.
+Added: of the Company as of March 31, 2026 have been prepared in accordance with the instructions to Form 10-Q and Article 10 of Regulation S-X
+Added: and, accordingly, they do not include all information and footnote disclosures required by accounting principles generally accepted in
+Added: The Company believes the footnotes and other disclosures made in the financial statements are adequate for a fair presentation
+Added: of the results of the interim periods presented.
+Added: In the opinion of management, all adjustments (consisting of normal recurring adjustments)
+Added: considered necessary for a fair presentation have been included.
+Added: Interim operating results are not necessarily indicative of results that
+Added: may be expected for the full year ending December 31, 2026, or for any subsequent period.
+Added: You should read these financial statements and
+Added: the accompanying notes in conjunction with the financial statements and notes thereto included in the Company’s Annual Report on
+Added: Form 10-K for the fiscal year ended December 31, 2025, filed with the U.S.
+Added: Securities and Exchange Commission on March 30, 2026.
Use of Estimates
6 unchanged sentences
could have a material effect on future results of operations and financial position.
−Removed: Significant items subject to such estimates and assumptions
−Removed: include stock-based compensation, research contract progress estimates, incremental borrowing rate for leases, useful life for assets,
−Removed: debt and equity transactions, and the valuation of warrant liabilities.
−Removed: Actual results may materially differ from those estimates.
+Added: Significant items subject to such estimates and
+Added: assumptions include stock-based compensation, research contract progress estimates, incremental borrowing rate for leases, useful life
+Added: for assets, valuation of marketable securities, equity transactions, and the valuation of warrant liabilities.
+Added: Actual results may materially
+Added: differ from those estimates.
+Added: Cash and Cash Equivalents
+Added: Highly liquid investments that are readily convertible
+Added: to cash and have original maturities of three months or less at the time of acquisition are considered cash equivalents.
+Added: As of December
+Added: 31, 2025, cash and cash equivalents consist of cash deposited with banks, money market funds, investment in corporate bonds with original
+Added: maturities of three months or less, and U.S.
+Added: Treasury bills.
+Added: As of March 31, 2026, cash and cash equivalents consist of cash deposited
+Added: with banks, money market funds, and investment in corporate bonds with original maturities of three months or less.
+Added: Marketable Securities
+Added: Marketable securities consist of corporate debt
+Added: securities with original maturities beyond three months at the date of purchase and which mature at, or less than twelve months from,
+Added: the balance sheet date.
+Added: The Company classifies its investment in marketable securities as available-for-sale, as the sale of such securities
+Added: may be required prior to maturity.
+Added: Management determines the appropriate classification of its investments in debt securities at the time
+Added: The Company obtains pricing information from its investment manager and generally determines the fair value of investment
+Added: securities using standard observable inputs, including reported trades, broker/dealer quotes, and bid and/or offers.
+Added: Available-for-sale
+Added: securities are carried at fair value, with the unrealized gains and losses reported as accumulated other comprehensive income (loss).The
+Added: carrying value of debt securities is adjusted for amortization of premiums and accretion of discounts to maturity, the net amount of which,
+Added: along with interest and realized gains and losses, is included under other income (expense) in the statements of operations and comprehensive
+Added: income (loss).
+Added: At each balance sheet date, the Company reviews
+Added: its available-for-sale debt securities that are in an unrealized loss position to determine whether the unrealized loss or any potential
+Added: credit losses should be recognized in the statements of operations.
+Added: For available-for-sale debt securities in an unrealized loss position,
+Added: the Company first assesses whether it intends to sell, or it is more likely than not that it will be required to sell the security before
+Added: recovery of its amortized cost basis.
+Added: If either of the criteria regarding intent or requirement to sell is met, the security’s
+Added: amortized cost basis is written down to fair value through net income (loss).
+Added: For available-for-sale securities that do not meet the
+Added: above criteria, the Company evaluates whether the decline in fair value has resulted from credit losses or other factors.
+Added: In making this
+Added: assessment, the Company considers the severity of the impairment, any changes in interest rates, changes to the underlying credit ratings
+Added: and forecasted recovery among other factors.
+Added: The credit-related portion of unrealized losses, and any subsequent improvements, are recorded
+Added: in other income, net through an allowance account.
+Added: There have been no impairment or credit losses recognized during any of the periods
Warrant Liability
1 unchanged sentence
Preferred Stock (see Note 9), the Company established a warrant liability as of March 3, 2023, representing the fair value of warrants
−Removed: that may be issued (and have since been issued – see Note 10), subject to shareholder approval, upon conversion of the Series A-1
−Removed: Preferred Stock which was received on June 26, 2023.
−Removed: The Company accounts for these warrants as liabilities (in accordance with
−Removed: ASC 480, Distinguishing Liabilities from Equity ) on the balance sheets as a result of certain redemption clauses that are not within
−Removed: the control of the Company.
−Removed: The warrant liability was initially measured at fair value and is remeasured at fair value each reporting
−Removed: Changes in the fair value of the warrant liability are recognized in earnings during each period.
−Removed: The warrant liability is measured
−Removed: using Level 3 fair value inputs.
−Removed: See Note 10 for a description of warrant liability and the related valuations.
+Added: that may be issued (and have since been issued), subject to shareholder approval, upon conversion of the Series A-1 Preferred Stock which
+Added: was received on June 26, 2023.
+Added: The Company accounts for these warrants as liabilities (in accordance with ASC 480, Distinguishing
+Added: Liabilities from Equity ) on the balance sheets as a result of certain redemption clauses that are not within the control of the Company.
+Added: The warrant liability was initially measured at fair value and is remeasured at fair value each reporting period.
+Added: Changes in the fair
+Added: value of the warrant liability are recognized in earnings during each period.
+Added: The warrant liability is measured using Level 3 fair value
+Added: See Note 11 for a description of the Company’s warrant liability and the related valuations.
Segment Information
8 unchanged sentences
Information on net (loss) income and operating (loss) income is disclosed in the statements of operations.
−Removed: Segment expenses and other segment items are provided to the CODM on the same basis as disclosed in the Statements of Operations.
+Added: Segment expenses and other segment items are provided to the CODM on the same basis as disclosed in the statements of operations and
+Added: comprehensive income (loss).
The CODM does not evaluate performance or allocate
1 unchanged sentence
Risks and Uncertainties
−Removed: The Company operates in a dynamic and highly competitive
−Removed: industry and believes that changes in any of the following areas could have a material adverse effect on the Company’s future financial
−Removed: position, results of operations, or cash flows:
+Added: The Company operates in a dynamic and highly
+Added: competitive industry and believes that changes in any of the following areas could have a material adverse effect on the Company’s
+Added: future financial position, results of operations, or cash flows:
ability to obtain future financing;
−Removed: advances and trends in new technologies and industry
+Added: advances and trends in new technologies
+Added: and industry standards;
results of clinical trials;
regulatory approval and market acceptance of the Company’s products;
−Removed: development of sales
+Added: of sales channels;
certain strategic relationships;
−Removed: litigation or claims against the Company related to intellectual property, product, regulatory,
−Removed: or other matters;
+Added: litigation or claims against the Company related to intellectual property, product,
+Added: regulatory, or other matters;
and the Company’s ability to attract and retain employees necessary to support its growth.
5 unchanged sentences
the Company’s current product candidates or any future product candidates will receive the necessary approvals.
−Removed: If the Company is
−Removed: denied approval, approval is delayed or the Company is unable to maintain approval, it could have a materially adverse impact on the Company.
+Added: If the Company
+Added: is denied approval, approval is delayed or the Company is unable to maintain approval, it could have a materially adverse impact on the
The Company has expended and will continue to
expend substantial funds to complete the research, development and clinical testing of its product candidates.
−Removed: The Company also will be
−Removed: required to expend additional funds to establish commercial-scale manufacturing arrangements and to provide for the marketing and distribution
−Removed: of products that receive regulatory approval.
+Added: The Company also will
+Added: be required to expend additional funds to establish commercial-scale manufacturing arrangements and to provide for the marketing and
+Added: distribution of products that receive regulatory approval.
The Company will require additional funds to commercialize its products.
−Removed: The Company is
−Removed: unable to entirely fund these efforts with its current financial resources.
−Removed: If adequate funds are unavailable on a timely basis from operations
−Removed: or additional sources of financing, the Company may have to delay, reduce the scope of or eliminate one or more of its research or development
−Removed: programs, which would materially and adversely affect its business, financial condition and operations.
+Added: Company is unable to entirely fund these efforts with its current financial resources.
+Added: If adequate funds are unavailable on a timely
+Added: basis from operations or additional sources of financing, the Company may have to delay, reduce the scope of or eliminate one or more
+Added: of its research or development programs, which would materially and adversely affect its business, financial condition and operations.
The Company is dependent upon the services of
7 unchanged sentences
Depreciation is computed using the straight-line
−Removed: method over the estimated useful lives of the related assets, which range from three to seven years.
−Removed: Leasehold improvements are amortized
−Removed: on a straight-line basis over the shorter of their estimated useful lives or the remaining lease term.
+Added: method over the estimated useful lives of the related assets, which range from three to seven years for lab equipment and furniture and
+Added: Leasehold improvements are amortized on a straight-line basis over the shorter of their estimated useful lives or the remaining
Management assesses the carrying value of property
4 unchanged sentences
amount of the asset exceeds the estimated fair value of the asset.
−Removed: During the nine months ended September 30, 2024 and 2025, management
−Removed: determined there were no impairments of the Company’s property and equipment.
+Added: No impairment charges were recorded on the Company’s property
+Added: and equipment during the three months ended March 31, 2026 and 2025 .
+Added: During the three months ended March 31, 2026 the Company recorded
+Added: the disposal of fixed assets with the net book value of $ 18,000 which was associated with the old lease.
+Added: No proceeds were received in
+Added: the disposal.
The Company determines whether a contract is,
3 unchanged sentences
The Company records
−Removed: the right-of-use asset at the amount of the lease liability plus any prepaid rent, and initial direct costs, less any lease
−Removed: incentives and accrued rent.
−Removed: Lease liabilities are recognized at lease commencement based upon the estimated present value of unpaid lease
−Removed: payments over the lease term.
−Removed: The right-of-use assets are reviewed for impairment whenever events or changes in circumstances exist that
−Removed: indicate the carrying amount may not be recoverable.
−Removed: The Company uses its incremental borrowing rate based on the information available
−Removed: at lease commencement in determining the present value of unpaid lease payments.
+Added: the right-of-use asset at the amount of the lease liability plus any prepaid rent, and initial direct costs, less any lease incentives
+Added: and accrued rent.
+Added: Lease liabilities are recognized at lease commencement based upon the estimated present value of unpaid lease payments
+Added: over the lease term.
+Added: The right-of-use assets are reviewed for impairment whenever events or changes in circumstances exist that indicate
+Added: the carrying amount may not be recoverable.
+Added: The Company uses its incremental borrowing rate based on the information available at lease
+Added: commencement in determining the present value of unpaid lease payments.
Fair Value of Financial Instruments
The Company’s financial instruments include
−Removed: the warrant liability, cash and cash equivalents, accounts payable and accrued liabilities.
+Added: the cash and cash equivalents, investment in marketable securities, accounts payable, accrued liabilities, and warrant liabilities.
Fair value is defined as the price that would
3 unchanged sentences
contains the following levels:
−Removed: Level 1 — defined as observable inputs based on unadjusted quoted prices for identical instruments in active markets;
−Removed: Level 2 — defined as inputs other than Level 1 that are either directly or indirectly observable in the marketplace for identical or similar instruments in markets that are not active;
−Removed: Level 3 — defined as unobservable inputs in which little or no market data exists where valuations are derived from techniques in which one or more significant inputs are unobservable.
+Added: Level 1 — defined
+Added: as observable inputs based on unadjusted quoted prices for identical instruments in active markets;
+Added: Level 2 — defined
+Added: as inputs other than Level 1 that are either directly or indirectly observable in the marketplace for identical or similar instruments
+Added: in markets that are not active;
+Added: Level 3 — defined
+Added: as unobservable inputs in which little or no market data exists where valuations are derived from techniques in which one or more
+Added: significant inputs are unobservable.
The fair value of the warrant liability is determined
using a Black Scholes model with parameters including (i) the exercise price of the warrants, (ii) the price of the underlying security,
−Removed: (iii) the time to expiration, or expected term, (iv) the expected volatility of the underlying security, (v) the risk-free rate, and (vi)
−Removed: estimated probability assumptions surrounding the achievement by the Company of technical milestones associated with regulatory and commercial
+Added: (iii) the time to expiration, or expected term, (iv) the expected volatility of the underlying security, (v) the risk-free rate, and
+Added: (vi) estimated probability assumptions surrounding the achievement by the Company of technical milestones associated with regulatory
+Added: and commercial progress.
These valuation techniques involve management’s
estimates and judgment based on unobservable inputs and are classified in Level 3.
−Removed: The fair value estimates may not be indicative of the
−Removed: amounts that would be realized in a market exchange.
−Removed: Additionally, there may be inherent uncertainties or changes in the underlying assumptions
−Removed: used, which could significantly affect the current or future fair value estimates.
−Removed: Generally, a significant increase (decrease) in the
−Removed: probabilities of shareholder approval and the achievement of technical milestones would have resulted in a significantly higher (lower)
−Removed: fair value measurement;
−Removed: however, changes in other inputs such as expected term and price of the underlying common stock will have a directionally
−Removed: opposite impact on fair value measurement.
−Removed: The following table summarizes the fair value hierarchy of financial
−Removed: liabilities measured at fair value as of September 30, 2025 (in thousands):
+Added: The fair value estimates may not be indicative of
+Added: the amounts that would be realized in a market exchange.
+Added: Additionally, there may be inherent uncertainties or changes in the underlying
+Added: assumptions used, which could significantly affect the current or future fair value estimates.
+Added: Generally, a significant increase (decrease)
+Added: in the probabilities of shareholder approval and the achievement of technical milestones would have resulted in a significantly higher
+Added: (lower) fair value measurement;
+Added: however, changes in other inputs such as expected term and price of the underlying common stock will
+Added: have a directionally opposite impact on fair value measurement.
+Added: The following tables present the approximate
+Added: value of assets and liabilities measured at fair value on a recurring basis within the Company’s balance sheets as of March 31,
+Added: 2026 by the fair value hierarchy (in thousands):
+Added: Cash and cash equivalents
+Added: Total cash and cash equivalents at fair value
+Added: Corporate bonds
+Added: Total marketable securities at fair value
+Added: Refer to Note 3 for disclosures related
+Added: to cash equivalents and marketable securities.
Warrant liability
Total liabilities at fair value
−Removed: The following table summarizes the fair value
−Removed: hierarchy of financial liabilities measured at fair value as of December 31, 2024 (in thousands):
+Added: The following tables present the approximate
+Added: value of assets and liabilities measured at fair value on a recurring basis within the Company’s balance sheets as of December
+Added: 31, 2025 by the fair value hierarchy (in thousands):
+Added: Cash and cash equivalents
+Added: Total cash and cash equivalents at fair value
+Added: Corporate bonds
+Added: Total marketable securities at fair value
+Added: Refer to Note 3 for disclosures related
+Added: to cash equivalents and marketable securities.
Warrant liability
4 unchanged sentences
are attributable to unobservable inputs (in thousands):
−Removed: Nine months ended
−Removed: September 30,
+Added: Three Months Ended
Fair value at January 1, 2025
1 unchanged sentence
Fair value at March 31, 2025
−Removed: Change in fair value of warrants
−Removed: Fair value at June 30, 2024
−Removed: Change in fair value of warrants
−Removed: Fair value at September 30, 2024
−Removed: Nine months ended
−Removed: September 30,
+Added: Three Months Ended
Fair value at January 1, 2026
1 unchanged sentence
Fair value at March 31, 2026
−Removed: Change in fair value of warrants
−Removed: Fair value at June 30, 2025
−Removed: Change in fair value of warrants
−Removed: Fair value at September 30, 2025
−Removed: The expense relating to the change in fair value
−Removed: of the warrant liability of $ 6.8 million and $ 9.8 million for the nine months ended September 30, 2024 and September 30, 2025 respectively
+Added: The income relating to the change in fair value
+Added: of the warrant liability of $ 8.3 million and expense of $ 4.8 million for the three months ended March 31, 2025 and March 31, 2026, respectively,
is included in other income (expenses) in the statements of operations.
2 unchanged sentences
to estimate fair value.
−Removed: As of December 31, 2024, and September 30, 2025, the recorded values of cash and cash equivalents, accounts payable,
+Added: As of December 31, 2025, and March 31, 2026, the recorded values of cash and cash equivalents, accounts payable,
and accrued liabilities approximated fair value due to the short-term nature of the instruments.
−Removed: Cash and cash equivalents, accounts payable,
−Removed: and accrued liabilities are Level 1 financial instruments.
+Added: Cash and cash equivalents, accounts
+Added: payable, and accrued liabilities are Level 1 financial instruments.
Concentration of Credit Risk
8 unchanged sentences
to other adverse conditions in the financial or credit markets.
−Removed: No such losses have been incurred through September 30, 2025.
+Added: No such losses have been incurred through March 31, 2026.
Prepaid Expenses and Other Current Assets
8 unchanged sentences
salaries and bonuses, employee benefit costs and stock-based compensation expenses for the Company’s research and product development
−Removed: The Company expenses both internal and external research and development expenses as incurred.
+Added: The Company expenses both internal and external research and development costs as incurred.
General and Administrative Expenses
−Removed: General and administrative expenses represent
−Removed: personnel costs for employees involved in general corporate functions, including finance, accounting, legal and human resources, among
−Removed: Additional costs included in general and administrative expenses consist of professional fees for legal (including patent costs),
−Removed: audit and other consulting services, stock-based compensation and other general corporate overhead expenses.
+Added: General and administrative expenses consist principally
+Added: of payroll and personnel expenses, including salaries and bonuses, benefits and stock-based compensation expenses, professional fees
+Added: for legal (including patent costs), consulting, accounting and tax services, including information technology costs and utilities, and
+Added: other general corporate overhead expenses.
The Company expenses all costs as incurred in
8 unchanged sentences
The Company estimates the fair value of stock options using the Black-Scholes option-pricing model.
−Removed: The Black-Scholes model
−Removed: requires the input of subjective assumptions, including expected common stock volatility, expected dividend yield, expected term, risk-free
−Removed: interest rate, and the public market closing price of the Company’s underlying common stock on the date of grant.
+Added: The Black-Scholes
+Added: model requires the input of subjective assumptions, including expected common stock volatility, expected dividend yield, expected term,
+Added: risk-free interest rate, and the public market closing price of the Company’s underlying common stock on the date of grant.
The Company accounts for corporate income taxes
20 unchanged sentences
interest or penalties related to income tax matters in income tax expense.
−Removed: The Tax Cuts and Jobs Act of 2017 eliminated the
−Removed: option to immediately deduct research and development expenditures in the year incurred under Section 174, which became effective January
−Removed: We are monitoring legislation for any further changes to Section 174 and the impact, if any, to the financial statements in 2025.
−Removed: On July 4, 2025, the “One Big
−Removed: Beautiful Bill Act” (OBBBA) was signed into law.
−Removed: This legislation introduces a number of new changes to the Internal Revenue
−Removed: As the Company does not currently generate taxable income, we do not expect the legislation to have a material impact on our
−Removed: tax position.
−Removed: The Company will continue to maintain a full valuation allowance against its net deferred tax assets.
−Removed: Comprehensive Loss
−Removed: Comprehensive loss includes all changes in equity
−Removed: (net assets) during a period from non-owner sources.
−Removed: There were no elements of other comprehensive income (loss) in the periods presented,
−Removed: as a result comprehensive loss is the same as net loss for each period presented.
+Added: Accumulated Other Comprehensive Income (Loss)
+Added: Accumulated other comprehensive income (loss) includes
+Added: unrealized gains and losses on available for sale, securities and is recognized as separate components of stockholders’ equity,
+Added: As of March 31, 2026, accumulated comprehensive income of $ 6,000 related to marketable securities was recorded.
Net Income (Loss) per Share
2 unchanged sentences
Basic and diluted net income (loss)
−Removed: for common stock and for preferred stock is computed by dividing the sum of distributed earnings and undistributed earnings for each class
−Removed: of stock by the weighted average number of shares outstanding for each class of stock for the period.
−Removed: Diluted net income (loss) per share
−Removed: includes potentially dilutive securities outstanding for the period.
−Removed: See Note 12 for reconciliations of basic and diluted net income (loss)
+Added: for common stock and for preferred stock is computed by dividing the sum of distributed earnings and undistributed earnings for each
+Added: class of stock by the weighted average number of shares outstanding for each class of stock for the period.
+Added: Diluted net income (loss)
+Added: per share includes potentially dilutive securities outstanding for the period.
+Added: See Note 13 for reconciliations of basic and diluted net
+Added: income (loss) per share.
Recent Accounting Pronouncements
4 unchanged sentences
not expected to have a material impact on the Company’s financial position or results of operations upon adoption.
+Added: Accounting pronouncements recently adopted
Income Taxes Disclosures – In December
4 unchanged sentences
ASU 2023-09 is effective for public entities with annual periods beginning after December 15, 2024, with early adoption permitted.
−Removed: Company is currently evaluating the impact of this guidance on its consolidated financial statements.
+Added: Company adopted this standard prospectively for the year ended December 31, 2025.
Accounting pronouncements pending adoption
1 unchanged sentence
2024-03, Expense Disaggregation Disclosures (“ASU 2024-03”).
−Removed: ASU 2024-03 amends ASC 220, Comprehensive Income to expand income statement
−Removed: expense disclosures and require disclosure in the notes to the financial statements of specified information about certain costs and expenses.
+Added: ASU 2024-03 amends ASC 220, Comprehensive Income to expand income
+Added: statement expense disclosures and require disclosure in the notes to the financial statements of specified information about certain
+Added: costs and expenses.
ASU 2024-03 is required to be adopted for fiscal years commencing after December 15, 2026, with early adoption permitted.
−Removed: is currently evaluating the impact of adopting the standard on its financial statements.
+Added: The Company is currently evaluating the impact of adopting the standard on its financial statements.
+Added: In November 2025, the FASB issued ASU 2025-11, “Interim Reporting
+Added: (Topic 270) Narrow-Scope Improvements,” which clarified interim disclosure requirements and the applicability of Topic 270.
+Added: objective of the update is to provide clarity about current interim requirements.
+Added: The amendments in this update also include a disclosure
+Added: principle that requires entities to disclose events since the end of the last annual reporting period that have a material impact on the
+Added: The amendments in this ASU are required to be adopted for interim periods within annual reporting periods beginning after December
+Added: Early adoption is permitted.
+Added: The Company is currently evaluating the impact of adopting the standard on its financial statements.
+Added: Cash, Cash Equivalents, and Marketable
+Added: The following table summarizes the Company’s
+Added: investments as of March 31, 2026 (in thousands):
+Added: Investments in corporate bonds
+Added: Total cash, cash equivalents and
+Added: investments in marketable securities
+Added: The following table summarizes the Company’s
+Added: investments as of December 31, 2025 (in thousands):
+Added: Treasury Bills
+Added: Investments in corporate bonds
+Added: Total cash, cash equivalents and
+Added: investments in marketable securities
+Added: The Company classifies its investments in corporate
+Added: bonds as available-for-sale.
+Added: Unrealized gains and losses on these securities are included as a component of comprehensive income (loss).
+Added: The Company’s investments in corporate bonds as of March 31, 2026 is $ 17.2 million and as of December 31, 2025 was $ 12.1 million.
+Added: On March 31, 2026, the remaining contractual
+Added: maturities of all the Company’s available-for-sale investments were less than twelve months.
+Added: As of March 31, 2026, the Company
+Added: has not established an allowance for credit losses for any of its available-for-sale securities.
Significant Agreements
2 unchanged sentences
based in India.
−Removed: Pursuant to the Agreement, Shilpa provides certain development, manufacturing, supply and other CMC-related services related
−Removed: to the development and commercialization of Oxylanthanum Carbonate (“OLC”).
−Removed: In June 2024, the Company entered into the
−Removed: First Amendment to Manufacturing and Supply Agreement with Shilpa (the “Amendment”) in anticipation of an increased
−Removed: manufacturing demand for OLC.
−Removed: Pursuant to the Amendment, the Company has agreed to make a binding purchase order for tablets of OLC
−Removed: and Shilpa has agreed to deliver such order by September 30, 2025.
−Removed: In addition, the Company has agreed to order additional
−Removed: tablets for delivery between December 31, 2025, and September 30, 2026.
+Added: Pursuant to the Agreement, Shilpa provides certain development, manufacturing, supply and other CMC-related services
+Added: related to the development and commercialization of oxylanthanum carbonate (“OLC”).
+Added: In June 2024, the Company entered into the First Amendment to Manufacturing
+Added: and Supply Agreement with Shilpa (the “Amendment”) in anticipation of an increased manufacturing demand for OLC.
+Added: to the Amendment, the Company has agreed to make a binding purchase order for tablets of OLC and Shilpa had agreed to deliver such order
+Added: by September 30, 2025.
+Added: Additional purchases are based on approval of the drug.
Further, the Company has agreed to make certain milestone
payments and to provide certain funding to Shilpa for a new manufacturing line.
−Removed: The initial term of the Agreement shall continue
−Removed: until the eighth (8th) anniversary of the date of receipt by the Company of FDA approval of its NDA of OLC (the “Initial
−Removed: Following the Initial Term, the Agreement shall continue in effect for consecutive periods of four (4) years each
−Removed: unless earlier terminated pursuant to the terms of the Agreement.
−Removed: In October 2017, the Company entered into an exclusive
−Removed: license agreement with Sphaera, a stockholder, for the rights to further develop the drug candidate, UNI 494, for commercialization.
−Removed: payments were made upon execution of the agreement but payments for $ 50 ,000 will be due commencing with the initiation by the Company
+Added: The initial term of the Agreement shall continue until
+Added: the eighth (8th) anniversary of the date of receipt by the Company of FDA approval of its NDA of OLC (the “Initial Term”).
+Added: Following the Initial Term, the Agreement shall continue in effect for consecutive periods of four (4) years each unless earlier terminated
+Added: pursuant to the terms of the Agreement.
+Added: In October 2017, the Company entered into an
+Added: exclusive license agreement with Sphaera, a stockholder, for the rights to further develop the drug candidate, UNI 494, for commercialization.
+Added: No payments were made upon execution of the agreement but payments for $ 50 ,000 will be due commencing with the initiation by the Company
of a second clinical trial and $50,000 on completion of such trial.
2 unchanged sentences
Upon commercialization and sale of the drug product, royalty payments will also
−Removed: be payable quarterly to Sphaera equal to 2 % of net sales on the preceding quarter.
+Added: be payable quarterly to Sphaera equal to 2 % of net sales in the preceding quarter.
In September 2018, the Company entered into an
Assignment and Asset Purchase Agreement with Spectrum Pharmaceuticals, Inc.
−Removed: (“Spectrum Agreement”) pursuant to which the Company
−Removed: purchased certain assets from Spectrum, including Spectrum’s right, title, interest in and intellectual property related to Renazorb
−Removed: RZB 012, also known as RENALAN™ (“Renalan”) and RZB 014, also known as SPI 014 (“SPI” and together with
−Removed: Renalan, the “Compounds”), to further develop and commercialize Oxylanthanum Carbonate and related compounds.
−Removed: In partial consideration
−Removed: for the Spectrum Agreement, the Company issued 31,366 shares of common stock to Spectrum valued at approximately $ 4 ,000 which represented
−Removed: four percent of the Company on a fully-diluted basis at the date of the execution of the Spectrum Agreement.
−Removed: The Spectrum Agreement has
−Removed: an anti-dilution provision, which provides that Spectrum maintain its ownership interest in the Company at 4 % of the Company’s shares
−Removed: on a fully-diluted basis.
−Removed: Fully-diluted shares of common stock for purposes of the Oxylanthanum Carbonate Purchase Agreement assumes conversion
−Removed: of any security convertible into or exchangeable or exercisable for common stock or any combination thereof, including any common stock
−Removed: reserved for issuance under a stock option plan, restricted stock plan, or other equity incentive plan approved by the Board of Directors
−Removed: of the Company immediately following the issuance of additional shares of the Company’s common stock (but prior to the issuance
−Removed: of any additional shares of common stock to Spectrum).
−Removed: Spectrum’s ownership shall not be subject to dilution until the earlier of
−Removed: thirty-six months from the first date the Company’s stock trades on a public market, or the date upon which the Company attains
−Removed: a public market capitalization of at least $ 50 million.
−Removed: On July 13, 2021, the Company’s initial public offering resulted in a public
−Removed: market capitalization of at least $ 50 million, and as a result the Company was required to issue 43,838 anti-dilution shares of common
−Removed: This issuance represented the final anti-dilution calculation required under the Spectrum Agreement, and no further anti-dilution
−Removed: shares will be issued.
−Removed: The Company calculated the fair value of the shares and recognized $ 2.2 million to research and development expenses
−Removed: as cost to issue those shares during the third quarter of 2021.
−Removed: In the event an NDA filing for Oxylanthanum Carbonate is accepted by the
−Removed: FDA, the Company will be required to pay $ 0.2 million to Altair Nanomaterials, Inc., (“Altair”) in accordance with the Spectrum
−Removed: In addition, in the event FDA approval for Oxylanthanum Carbonate is received, the Company will be required to pay $ 4.5 million
−Removed: The Company is also required to pay Spectrum 40 % of all the Company’s sublicense income for any sublicense granted to
−Removed: certain sublicensees during the first 12 months after the Closing Date (as that term is defined in the Spectrum Agreement) and 20 % of
−Removed: all other sublicense income.
−Removed: The Company’s payment obligations to Spectrum will expire on the twentieth (20th) anniversary of the
−Removed: Closing Date of the Spectrum Agreement.
−Removed: In August 2022, the Company received an upfront payment of approximately $ 1.0 million resulting
−Removed: from a sublicense development agreement with Lee’s Pharmaceutical (HK) Limited.
−Removed: In February 2023, the Company received an upfront
−Removed: payment of approximately $ 0.7 million resulting from a sublicense development agreement with Lotus International Pte Ltd.
−Removed: represents sublicense income as described in the Spectrum Agreement, and 20 % of the amount received has been accrued as an R&D expense
−Removed: in the accompanying statements of operations for the nine months ended September 30, 2025.
−Removed: On January 6, 2022, the Company entered into a
−Removed: Master Services Agreement with Quotient Sciences Limited (“Quotient”), a UK based company that provides drug development and
−Removed: analysis services, for the purpose of performing clinical research in support of UNI-494.
−Removed: The initial budget for the study is approximately
−Removed: $ 3.7 million, and subsequent revisions reduced the overall budget to $ 2.9 million.
−Removed: Related payments totaling approximately $ 2.9 million
−Removed: have been paid to Quotient as of September 30, 2025, approximately $ 2.9 million of related expense has been recorded, and there is no
−Removed: prepaid balance in the accompanying balance sheets as of December 31, 2024 and September 30, 2025, respectively.
−Removed: On April 10, 2023, the Company entered into an
−Removed: agreement with Inotiv that provides preclinical trial and related services, for the purpose of performing research in support of UNI-494.
−Removed: The budget for these services is approximately $ 2.9 million.
−Removed: Approximately $ 2.9 million has been paid to Inotiv as of September 30, 2025
−Removed: and there is no prepaid balance in the accompanying balance sheets as of December 31, 2024 and September 30, 2025, respectively.
−Removed: On July 14, 2022, the Company entered into a license
−Removed: agreement with Lee’s Pharmaceutical (HK) Limited.
−Removed: Under the terms of the agreement, Lee’s Pharmaceutical will be responsible
−Removed: for development, registration filing and approval for Oxylanthanum Carbonate in China, Hong Kong, and certain other Asian markets.
−Removed: addition, Lee’s Pharmaceutical will have sole responsibility for the importation of the drug product from the Company and for the
−Removed: costs of commercialization of Oxylanthanum Carbonate in the licensed territories.
−Removed: The Company has received an upfront payment of $ 1.0
−Removed: million, expects to receive up to $ 1.0 million in milestone payments upon product launch in China and will be eligible for tiered royalties
−Removed: of between 7 % and 10 % upon achievement of prespecified regulatory and commercial achievements.
+Added: (“Spectrum Agreement”) pursuant to which the
+Added: Company purchased certain assets from Spectrum, including Spectrum’s right, title, interest in and intellectual property related
+Added: to Renazorb RZB 012, also known as RENALAN™ (“Renalan”) and RZB 014, also known as SPI 014 (“SPI” and together
+Added: with Renalan, the “Compounds”), to further develop and commercialize oxylanthanum carbonate and related compounds.
+Added: consideration for the Spectrum Agreement, the Company issued 31,366 shares of common stock to Spectrum valued at approximately $ 4 ,000
+Added: which represented four percent of the Company on a fully-diluted basis at the date of the execution of the Spectrum Agreement.
+Added: Agreement has an anti-dilution provision, which provides that Spectrum maintain its ownership interest in the Company at 4 % of the Company’s
+Added: shares on a fully-diluted basis.
+Added: Fully-diluted shares of common stock for purposes of the oxylanthanum carbonate Purchase Agreement assumes
+Added: conversion of any security convertible into or exchangeable or exercisable for common stock or any combination thereof, including any
+Added: common stock reserved for issuance under a stock option plan, restricted stock plan, or other equity incentive plan approved by the Board
+Added: of Directors of the Company immediately following the issuance of additional shares of the Company’s common stock (but prior to
+Added: the issuance of any additional shares of common stock to Spectrum).
+Added: Spectrum’s ownership shall not be subject to dilution until
+Added: the earlier of thirty-six months from the first date the Company’s stock trades on a public market, or the date upon which the
+Added: Company attains a public market capitalization of at least $ 50 million.
+Added: On July 13, 2021, the Company’s initial public offering
+Added: resulted in a public market capitalization of at least $ 50 million, and as a result the Company was required to issue 43,838 anti-dilution
+Added: shares of common stock.
+Added: This issuance represented the final anti-dilution calculation required under the Spectrum Agreement, and no further
+Added: anti-dilution shares will be issued.
+Added: The Company calculated the fair value of the shares and recognized $ 2.2 million to research and
+Added: development expenses as cost to issue those shares during the third quarter of 2021.
+Added: In the event an NDA filing for oxylanthanum carbonate
+Added: is accepted by the FDA, the Company will be required to pay $ 0.2 million to Altair Nanomaterials, Inc., (“Altair”) in accordance
+Added: with the Spectrum Agreement.
+Added: In addition, in the event FDA approval for oxylanthanum carbonate is received, the Company will be required
+Added: to pay $ 4.5 million to Altair.
+Added: The Company is also required to pay Spectrum 40 % of all the Company’s sublicense income for any
+Added: sublicense granted to certain sublicensees during the first 12 months after the Closing Date (as that term is defined in the Spectrum
+Added: Agreement) and 20 % of all other sublicense income.
+Added: The Company’s payment obligations to Spectrum will expire on the twentieth (20th)
+Added: anniversary of the Closing Date of the Spectrum Agreement.
+Added: In August 2022, the Company received an upfront payment of approximately $ 1.0
+Added: million resulting from a sublicense development agreement with Lee’s Pharmaceutical (HK) Limited.
+Added: In February 2023, the Company
+Added: received an upfront payment of approximately $ 0.7 million resulting from a sublicense development agreement with Lotus International
+Added: The payment represents sublicense income as described in the Spectrum Agreement, and 20 % of the amount received has been accrued
+Added: as an R&D expense in the accompanying statements of operations for the year ended March 31, 2026.
+Added: On July 14, 2022, the Company entered into a
+Added: license agreement with Lee’s Pharmaceutical (HK) Limited.
+Added: Under the terms of the agreement, Lee’s Pharmaceutical will be
+Added: responsible for development, registration filing and approval for oxylanthanum carbonate in China, Hong Kong, and certain other Asian
+Added: In addition, Lee’s Pharmaceutical will have sole responsibility for the importation of the drug product from the Company
+Added: and for the costs of commercialization of oxylanthanum carbonate in the licensed territories.
+Added: The Company has received an upfront payment
+Added: of $ 1.0 million, expects to receive up to $ 1.0 million in milestone payments upon product launch in China and will be eligible for tiered
+Added: royalties of between 7 % and 10 % upon achievement of prespecified regulatory and commercial achievements.
On February 1, 2023, the Company entered into
9 unchanged sentences
entered into services agreements with Shilpa related to NDA filing support for oxylanthanum carbonate.
−Removed: The agreements provide for
−Removed: total payments of up to $ 4.5 million, and the Company has made $ 4.5 million in payments pursuant to the agreements as of September 30,
+Added: The agreements provide for total
+Added: payments of up to $ 4.5 million, all of which has been paid as of March 31, 2026.
Balance Sheet Components
−Removed: Prepaid expenses and other current assets as of
−Removed: December 31, 2024 and September 30, 2025 consisted of the following (in thousands):
−Removed: September 30,
+Added: Prepaid expenses and other current assets as
+Added: of December 31, 2025 and March 31, 2026 consisted of the following (in thousands):
Prepaid directors’ and officers’ liability insurance premiums
Prepaid drug manufacturing supply costs
−Removed: Property and equipment as of December 31, 2024 and September 30, 2025
−Removed: consisted of the following (in thousands):
−Removed: September 30,
+Added: Property and equipment as of December 31, 2025
+Added: and March 31, 2026 consisted of the following (in thousands):
Leasehold improvements
2 unchanged sentences
Less accumulated depreciation
−Removed: Accounts payable as of December 31, 2024 and September
−Removed: 30, 2025 consisted of the following (in thousands):
−Removed: September 30,
+Added: Depreciation expense was immaterial for the three
+Added: months ended March 31, 2026 and 2025 and is included in general and administrative expenses.
+Added: Accounts payable as of December 31, 2025 and
+Added: March 31, 2026 consisted of the following (in thousands):
Trade accounts payable
1 unchanged sentence
Accrued liabilities as of December 31, 2025 and
−Removed: September 30, 2025 consisted of the following (in thousands):
−Removed: September 30,
+Added: March 31, 2026 consisted of the following (in thousands):
Accrued labor costs
1 unchanged sentence
Operating Lease
−Removed: The Company leases office space under an
−Removed: operating lease.
−Removed: In December 2021, the Company entered into a lease agreement for 2,367 square feet of office space commencing
−Removed: December 1, 2021.
−Removed: The initial lease term was for two years , and there was an option to extend the lease for an additional year.
−Removed: March 3, 2023, the Company expanded its leased space through a lease amendment by an additional 2,456 square feet commencing March
−Removed: The term of the amended lease is for three years with an option to extend the lease for three additional years .
−Removed: 28, 2024, the Company further expanded its leased space through a lease amendment by an additional 2,581 square feet commencing July
−Removed: The term of the amended lease unifies with the current expiration of the lease which is March 31, 2026.
−Removed: The lease amendment represents a modification
−Removed: of the original lease, and the Company evaluated the new agreement under ASC 842, Leases.
−Removed: The Company classified the lease as an operating
−Removed: lease and, on July 15, 2024, determined that the present value of the lease was approximately $ 1.0 million using an estimated incremental
−Removed: borrowing rate of 10 %.
−Removed: During the nine months ended September 30, 2024 and September 30, 2025, the Company reflected amortization of right-of-use
−Removed: asset of approximately $ 0.3 million and $ 0.4 million, respectively, resulting in a right-of-use asset balance of approximately
−Removed: $ 0.2 million at September 30, 2025.
−Removed: During the nine months ended September 30, 2024
−Removed: and September 30, 2025, the Company made cash payments on the lease of $ 0.3 million and $ 0.5 million, respectively towards the lease liabilities.
−Removed: As of September 30, 2025, the total lease liability was approximately $ 0.3 million.
−Removed: As of September 30, 2025, maturities of the Company’s
−Removed: lease liabilities are as follows (in thousands, unaudited):
+Added: The Company leases office space under operating lease arrangements.
+Added: During the three months ended March 31, 2026, the Company’s
+Added: previously amended operating lease for 7,404 square feet of office space expired.
+Added: In connection with this lease, the Company made lease
+Added: payments of approximately $ 0.1 million.
+Added: In November 2025, the Company entered into a
+Added: new operating lease for 10,734 square feet of office space, which commenced on February 1, 2026.
+Added: The lease has an initial term of 1.5
+Added: years and includes an option to extend the term for an additional year at the Company’s discretion.
+Added: At lease commencement, the
+Added: Company recognized a right-of-use asset and corresponding lease liability based on the present value of the remaining lease payments.
+Added: Because the lease does not provide a readily determinable implicit rate, the Company used its estimated incremental borrowing rate as
+Added: of the commencement date.
+Added: Operating lease cost is recognized on a straight-line basis over the lease term and is included in general
+Added: and administrative expenses in the statements of operations.
+Added: During the three months ended March 31, 2026, the Company made lease payments
+Added: of approximately $ 0.1 million.
+Added: During the three months ended March 31, 2026,
+Added: the Company reflected amortization of right-of-use asset of approximately $ 0.1 million, resulting in a right-of-use asset balance of
+Added: approximately $ 0.8 million at March 31, 2026.
+Added: During the three months ended March 31, 2026, the Company made cash payments on the lease
+Added: of $ 0.1 million towards the lease liability.
+Added: As of March 31, 2026, the total lease liability was approximately $ 0.8 million.
+Added: As of March 31, 2026, maturities of the Company’s
+Added: lease liabilities are as follows (in thousands):
Operating Lease
6 unchanged sentences
Long term portion
+Added: The remaining lease term and discount rates related
+Added: to the Company’s right of use assets and lease liabilities for its operating leases were as follows:
+Added: December 31, March 31,
+Added: Remaining lease term (in years) 0.25 1.33
+Added: Incremental borrowing rate 10 % 8.75 %
Commitments and Contingencies
Contingencies
−Removed: The Company is subject to claims and legal
−Removed: proceedings that arise in the ordinary course of business.
−Removed: Such matters are inherently uncertain, and there can be no guarantee that
−Removed: the outcome of any such matter will be decided favorably to the Company or that the resolution of any such matter will not have a
−Removed: material adverse effect upon the Company’s financial statements.
−Removed: On August 15, 2025, a putative shareholder class action
−Removed: complaint captioned Elkhodari v.
+Added: The Company is subject to claims and legal proceedings
+Added: that arise in the ordinary course of business.
+Added: Such matters are inherently uncertain, and there can be no guarantee that the outcome
+Added: of any such matter will be decided favorably to the Company or that the resolution of any such matter will not have a material adverse
+Added: effect upon the Company’s financial statements.
+Added: On August 15, 2025, a putative shareholder class action complaint captioned Elkhodari
Unicycive Therapeutics, Inc., et al.
−Removed: 3:25-cv-06923-JD (the “Securities Class
−Removed: Action”), was filed in the U.S.
−Removed: District Court for the Northern District of California, naming the Company and certain current
−Removed: officers and/or directors of the Company as defendants.
−Removed: The lawsuit alleges that the Company made material misrepresentations and/or
−Removed: omissions of material fact relating to the prospects of a New Drug Application (“NDA”) for oxylanthanum carbonate
−Removed: (“OLC”) for the treatment of hyperphosphatemia in CKD patients on dialysis (the “OLC NDA”) in violation of
−Removed: Sections 10(b) and 20(a) of the Securities Exchange Act of 1934 (the “Exchange Act”) and Rule 10b-5 promulgated
−Removed: The putative class action is brought on behalf of persons or entities who purchased or otherwise acquired the
−Removed: Company’s securities between March 29, 2024, and June 27, 2025, inclusive, and seeks unspecified monetary damages on behalf of
−Removed: the putative class and an award of costs and expenses, including attorneys’ fees.
−Removed: A hearing on the motion for Lead Plaintiff
−Removed: is currently set for November 20, 2025.
−Removed: At this early stage of the proceedings, the Company is unable to make any prediction
−Removed: regarding the outcome of the Securities Class Action.
−Removed: On October 30 and November 7, 2025, two shareholder
−Removed: derivative actions captioned Jackson v.
−Removed: Gupta, et al.
−Removed: 3:25-cv-09338-SK (the “ Jackson Action”), and
−Removed: Gupta, et al.
−Removed: 3:25-cv-09625-PHK (the “ Henry Action” and collectively with the Jackson
−Removed: Action, the “Derivative Actions”), respectively, were filed in the U.S.
−Removed: District Court for the Northern District of California
−Removed: against certain members of the Company’s board of directors and officers.
−Removed: The plaintiffs purport to bring these actions derivatively
−Removed: on behalf of the Company, and the Company is a nominal defendant in the action.
−Removed: The derivative complaints allege, among other things,
−Removed: that the individual defendants authorized or permitted materially false statements and/or material omissions regarding the prospects of
−Removed: the Company’s OLC NDA.
−Removed: The derivative complaints assert claims for violations of Section 14(a) of the Exchange Act and Rule 14a-9
−Removed: promulgated thereunder, as well as claims for breach of fiduciary duty, gross mismanagement, waste of corporate assets, and unjust enrichment.
−Removed: The derivative complaints seek unspecified damages on behalf of the Company, corporate governance reforms, disgorgement and restitution,
−Removed: and an award of costs and expenses to the derivative plaintiff, including attorneys’ fees.
−Removed: At this early stage of the proceedings,
−Removed: the Company is unable to make any prediction regarding the outcome of the Derivative Actions.
−Removed: It is possible that additional lawsuits will be
−Removed: filed or allegations will be made by stockholders with respect to these same or other matters also naming the Company and/or our officers
+Added: 3:25-cv-06923-JD (the “Securities Class Action”), was filed in the
+Added: District Court for the Northern District of California (“Northern District of California”), naming the Company and certain
+Added: current officers and/or directors of the Company as defendants.
+Added: The lawsuit generally alleges that the Company made material misrepresentations
+Added: and/or omissions of material fact relating to the Company’s manufacturing of oxylanthanum carbonate (“OLC”) and the
+Added: approval prospects of its New Drug Application for OLC for the treatment of hyperphosphatemia in CKD patients on dialysis in violation
+Added: of Sections 10(b) and 20(a) of the Securities Exchange Act of 1934 (the “Exchange Act”) and Rule 10b-5 promulgated thereunder.
+Added: The putative class action is brought on behalf of persons or entities who purchased or otherwise acquired the Company’s securities
+Added: between March 29, 2024, and June 27, 2025, inclusive, and seeks unspecified monetary damages on behalf of the putative class and an award
+Added: of costs and expenses, including attorneys’ fees.
+Added: On January 27, 2026, lead plaintiff filed an amended complaint.
+Added: 2026, defendants filed their motion to dismiss the amended complaint.
+Added: On April 27, 2026, lead plaintiff filed his opposition to the motion
+Added: On October 30 and November 7, 2025, two purported
+Added: stockholders of the Company filed derivative complaints in the Northern District of California against certain of the Company’s
+Added: current officers and directors (collectively, the “Derivative Actions”).
+Added: The Company is named as a nominal defendant.
+Added: complaints are based on the same alleged misconduct as in the Securities Class Action.
+Added: The complaints assert state law claims on behalf
+Added: of the Company against the individual defendants for breach of fiduciary duty, unjust enrichment, gross mismanagement, and waste of corporate
+Added: assets, and federal law claims under Section 14(a) of the Exchange Act.
+Added: On November 20, 2025, the Court issued an order relating the
+Added: Derivative Actions to the Securities Class Action, and on April 30, 2026, the Court consolidated the Derivative Actions.
+Added: The Derivative
+Added: Actions seek unspecified damages on behalf of the Company, corporate governance reforms, disgorgement and restitution, and an award of
+Added: costs and expenses, including attorneys’ fees.
+Added: On March 12, 2026, a purported stockholder made
+Added: a demand on the Company’s Board of Directors to commence a civil action against certain of the Company’s current and former
+Added: officers and directors for breaching their fiduciary duties based on the same alleged misconduct as alleged in the above-mentioned Securities
+Added: Class Action and Derivative Actions (the “Demand”).
+Added: On March 30, 2026, the Company’s Board of Directors responded that
+Added: it would defer a final decision on the Demand given the pendency of the Securities Class Action and the Derivative Actions.
+Added: At this early stage of the proceedings, the Company
+Added: is unable to make any prediction regarding the outcome of the Securities Class Action, the Derivative Actions, or the Demand.
+Added: It is possible that additional lawsuits will
+Added: be filed or allegations will be made by stockholders with respect to these same or other matters also naming the Company and/or our officers
and directors as defendants.
The Company intends to vigorously defend against the claims brought by the plaintiffs in each of these matters.
−Removed: Such lawsuits are subject to inherent uncertainties, and the actual
−Removed: defense and disposition costs will depend upon many unknown factors.
−Removed: The outcome of the pending lawsuits and any other related lawsuits
−Removed: is necessarily uncertain.
−Removed: The Company could be forced to expend significant resources and may incur substantial legal fees and costs in
−Removed: defending against the pending lawsuits and any other related lawsuits, and we may not prevail.
−Removed: Monitoring, initiating and defending against
−Removed: legal actions is time-consuming for our management, is likely to be expensive, and may detract from the ability to fully focus internal
−Removed: resources on business activities.
−Removed: Additionally, the Company may not be successful in having any such lawsuits dismissed or settled within
−Removed: the limits of insurance coverage.
−Removed: Given the early stage of these lawsuits and the inherent uncertainty of litigation, the Company cannot
−Removed: predict how long it may take to resolve the pending lawsuits or the potential outcome or possible amount of any damages.
−Removed: As such, we currently
−Removed: are unable to reasonably estimate the possible losses or a range of possible losses that may result from these matters, if any.
−Removed: associated with the pending lawsuits and any potential related lawsuits could be material to the consolidated financial statements if
−Removed: we do not prevail in the defense of such lawsuits, or even if we do prevail.
+Added: Such lawsuits are subject to inherent uncertainties,
+Added: and the actual defense and disposition costs will depend upon many unknown factors.
+Added: The outcome of the pending lawsuits and any other
+Added: related lawsuits is necessarily uncertain.
+Added: The Company could be forced to expend significant resources and may incur substantial legal
+Added: fees and costs in defending against the pending lawsuits and any other related lawsuits, and we may not prevail.
+Added: Monitoring, initiating
+Added: and defending against legal actions is time-consuming for our management, is likely to be expensive, and may detract from the ability
+Added: to fully focus internal resources on business activities.
+Added: Additionally, the Company may not be successful in having any such lawsuits
+Added: dismissed or settled within the limits of insurance coverage.
+Added: Given the early stage of these lawsuits and the inherent uncertainty of
+Added: litigation, the Company cannot predict how long it may take to resolve the pending lawsuits or the potential outcome or possible amount
+Added: of any damages.
+Added: As such, we currently are unable to reasonably estimate the possible losses or a range of possible losses that may result
+Added: from these matters, if any.
+Added: Expenses associated with the pending lawsuits and any potential related lawsuits could be material to the
+Added: financial statements if we do not prevail in the defense of such lawsuits, or even if we do prevail.
Indemnification
27 unchanged sentences
Company contributions to the 401(k) Plan totaled approximately $ 42,000 and $ 55,000 for the
−Removed: nine months ended September 30, 2024 and September 30, 2025, respectively.
−Removed: Stockholders’ Equity Deficit
+Added: three months ended March 31, 2025 and March 31, 2026, respectively.
+Added: Stockholders’ Equity
Authorized Common Stock
2 unchanged sentences
Reverse Stock Split
−Removed: On June 18, 2025, the Company filed the
−Removed: Charter Amendment with the Secretary of State of the State of Delaware to effectuate a reverse stock split.
−Removed: The Company’s
−Removed: common stock began trading on a split-adjusted basis at the opening of trading on the Nasdaq Capital Market on June 20, 2025.
−Removed: the reverse stock split became effective, every 10 shares of common stock were automatically reclassified and combined into one
−Removed: share of common stock.
+Added: On June 18, 2025, the Company filed a certificate
+Added: of amendment to its certificate of incorporation with the Secretary of State of the State of Delaware to effectuate a 1-for-10 reverse
+Added: The Company’s common stock began trading on a split-adjusted basis at the opening of trading on the Nasdaq Capital
+Added: Market on June 20, 2025.
+Added: When the reverse stock split became effective, every 10 shares of common stock were automatically reclassified
+Added: and combined into one share of common stock.
No fractional shares were issued as a result of the split.
−Removed: Stockholders who would otherwise be entitled to
−Removed: receive a fractional share will instead automatically have their fractional interests rounded up to the next whole share, after
−Removed: aggregating all the fractional interests of a holder resulting from the split.
−Removed: The split affects all stockholders uniformly and will
−Removed: not change any stockholder’s percentage ownership interest or any stockholder’s proportionate voting power, except for
−Removed: immaterial changes that may result from the treatment of fractional shares.
−Removed: The split did not change the number of authorized shares
−Removed: of common stock or the par value per share of the common stock.
+Added: Stockholders who would otherwise
+Added: have received a fractional share automatically had their fractional interests rounded up to the next whole share, after aggregating all
+Added: the fractional interests of a holder resulting from the split.
+Added: The reverse stock split affected all stockholders uniformly and will not
+Added: change any stockholder’s percentage ownership interest or any stockholder’s proportionate voting power, except for immaterial
+Added: changes that may result from the treatment of fractional shares.
+Added: The split did not change the number of authorized shares of common stock
+Added: or the par value per share of the common stock.
As a result of the reverse stock split, proportionate
9 unchanged sentences
Initial Public Offering
−Removed: During July 2021, as a result of its initial public
−Removed: offering, the Company issued 500,000 shares of common stock and 400,000 warrants to investors in exchange for cash at $ 50.00 per unit,
−Removed: consisting of $ 49.90 per share of common stock and $.
+Added: During July 2021, as a result of its initial
+Added: public offering, the Company issued 500,000 shares of common stock and 400,000 warrants to investors in exchange for cash at $ 50.00 per
+Added: unit, consisting of $ 49.90 per share of common stock and $.
0.10 per four fifths of a warrant.
−Removed: The warrants have a 5 -year term and an exercise
−Removed: price of $ 60.00 per warrant.
−Removed: The underwriters exercised their option to purchase an additional 60,000 warrants, and the Company received
−Removed: $ 7,500 in proceeds.
+Added: The warrants have a 5 -year term and an
+Added: exercise price of $ 60.00 per warrant.
+Added: The underwriters exercised their option to purchase an additional 60,000 warrants, and the Company
+Added: received $ 7,500 in proceeds.
As a result of the initial public offering, the
5 unchanged sentences
are equity classified.
−Removed: The following table summarizes activity for the Company’s IPO warrants for the nine months ended September
+Added: The following table summarizes activity for the Company’s IPO warrants for the three months ended March
Number of Average
6 unchanged sentences
Warrants exercised - - - -
−Removed: Outstanding, September 30, 2025 478,419 60.00 0.79 -
−Removed: See Note 10 for information on preferred stock
−Removed: warrants associated with our sale in March 2023 of Series A-1 Preferred Stock.
−Removed: Issuance of Common Stock Upon Conversion of Series A and Series
−Removed: B Preferred Stock
+Added: Outstanding, March 31, 2026 478,419 60.00 0.29 -
+Added: Issuance of Common Stock Upon Conversion of
+Added: Series A and Series B Preferred Stock
On June 26, 2023, the Company held its annual
shareholder meeting and, as a result, shareholder approval for the issuance of common shares upon the conversion of the Series A-1 Preferred
−Removed: Stock was obtained (see Notes 8 and 9).
+Added: Stock was obtained (see Note 9).
On July 11, 2023, pursuant to the Certificate of Designation of Preferences, Rights and Limitations
8 unchanged sentences
conversion of the Series B-1 Convertible Preferred Stock.
−Removed: On June 25, 2024, the Company issued 595,600 shares
−Removed: of common stock upon conversion of 2,918.44 shares of the Company’s Series A-2 Prime Preferred Stock.
−Removed: On July 23, 2024, the Company issued 355,000 shares
−Removed: of common stock upon conversion of 1,739.50 shares of the Company’s Series A-2 Prime Preferred Stock.
−Removed: On July 25, 2024, the Company issued 375,600 shares
−Removed: of common stock upon conversion of 1,840.44 shares of the Company’s Series A-2 Prime Preferred Stock.
−Removed: On July 29, 2024, the Company issued 135,900 shares
−Removed: of common stock upon conversion of 665.91 shares of the Company’s Series A-2 Prime Preferred Stock.
+Added: On June 25, 2024, the Company issued 595,600
+Added: shares of common stock upon conversion of 2,918.44 shares of the Company’s Series A-2 Prime Preferred Stock.
+Added: On July 23, 2024, the Company issued 355,000
+Added: shares of common stock upon conversion of 1,739.50 shares of the Company’s Series A-2 Prime Preferred Stock.
+Added: On July 25, 2024, the Company issued 375,600
+Added: shares of common stock upon conversion of 1,840.44 shares of the Company’s Series A-2 Prime Preferred Stock.
+Added: On July 29, 2024, the Company issued 135,900
+Added: shares of common stock upon conversion of 665.91 shares of the Company’s Series A-2 Prime Preferred Stock.
On August 14, 2024, the Company issued 350,200
12 unchanged sentences
shares of common stock upon conversion of 686 shares of the Company’s Series A-2 Prime Preferred Stock.
−Removed: On June 11, 2025, the Company issued 300,000 shares
−Removed: of common stock upon conversion of 3,000 shares of the Company’s Series B-2 Preferred Stock.
+Added: In June 2025, the Company issued 277,000 shares
+Added: of common stock upon the exercise and conversion of Series A-3 warrants and received $ 1.5 million in exercise proceeds.
+Added: On June 11, 2025, the Company issued 300,000
+Added: shares of common stock upon conversion of 3,000 shares of the Company’s Series B-2 Preferred Stock.
On August 26, 2025, the Company issued 652,900
8 unchanged sentences
The Company has used the net proceeds from
−Removed: the Preferred Stock Offering to support the Company’s “New Drug Application” (NDA) submission for approval of
−Removed: Oxylanthanum Carbonate for the treatment of hyperphosphatemia and, if approved, for the commercial launch of Oxylanthanum Carbonate in
+Added: the Preferred Stock Offering to support the Company’s “New Drug Application” (NDA) submission for approval of oxylanthanum
+Added: carbonate for the treatment of hyperphosphatemia and, if approved, for the commercial launch of oxylanthanum carbonate in the U.S.
Pursuant to the Series A Certificate of Designation,
17 unchanged sentences
The Series A Preferred Stock has a par value of $ 0.001 per share.
−Removed: The Series A Certificate of Designation states that, to the extent that
−Removed: the conversion of the Series A-1 preferred stock as well as the exercise of the Warrants into Series A-2, Series A-3, Series A-4, and
−Removed: Series A-5 preferred stock results in a beneficial ownership interest in excess of the maximum percentage of common stock upon conversion,
+Added: The Series A Certificate of Designation states that, to the extent
+Added: that the conversion of the Series A-1 preferred stock as well as the exercise of the Warrants into Series A-2, Series A-3, Series A-4,
+Added: and Series A-5 preferred stock results in a beneficial ownership interest in excess of the maximum percentage of common stock upon conversion,
the holders will receive the as converted equivalent for the remaining shares in preferred stock.
−Removed: The Company determined that the Warrants are freestanding
−Removed: from the Series A-1 Preferred Stock, because the stock will automatically convert into shares of common stock, and the holders will be
−Removed: able to sell those shares while retaining the Warrants.
−Removed: The Company noted that at contract inception, the Warrants were contingently issuable
−Removed: upon the occurrence of a specified event (shareholder approval).
+Added: The Company determined that the Warrants are
+Added: freestanding from the Series A-1 Preferred Stock, because the stock will automatically convert into shares of common stock, and the holders
+Added: will be able to sell those shares while retaining the Warrants.
+Added: The Company noted that at contract inception, the Warrants were contingently
+Added: issuable upon the occurrence of a specified event (shareholder approval).
In connection with the Series A-1 Preferred Stock
3 unchanged sentences
was accounted for as a reduction to the net proceeds of the Preferred Stock Offering, which resulted in an initial carrying value of
−Removed: million for the Series A-1 Preferred Stock (net of $ 2.0 million of placement agent fees and offering costs allocated to the Series A-1
−Removed: Preferred Stock).
−Removed: Refer to Note 10 for disclosures related to the Warrants.
−Removed: On June 26, 2023, the Company held its
−Removed: annual shareholder meeting and, as a result, shareholder approval for the conversion of the Series A-1 Preferred Stock was obtained.
−Removed: On July 11, 2023, pursuant to the Series A Certificate of Designation, the Company issued 1,951,621 shares of common stock and
−Removed: 43,649 shares of Series A-2 Preferred Stock in partial settlement of the auto-conversion of the Series A-1 preferred shares.
−Removed: December 31, 2023, there were zero shares of Series A-1 preferred stock issued and outstanding and there were 43,649 shares of
−Removed: Series A-2 Preferred Stock issued and outstanding.
+Added: $ 25.4 million for the Series A-1 Preferred Stock (net of $ 2.0 million of placement agent fees and offering costs allocated to the Series
+Added: A-1 Preferred Stock).
+Added: On June 26, 2023, the Company held its annual
+Added: shareholder meeting and, as a result, shareholder approval for the conversion of the Series A-1 Preferred Stock was obtained.
+Added: 11, 2023, pursuant to the Series A Certificate of Designation, the Company issued 1,951,621 shares of common stock and 43,649 shares
+Added: of Series A-2 Preferred Stock in partial settlement of the auto-conversion of the Series A-1 preferred shares.
+Added: As of December 31, 2023,
+Added: there were zero shares of Series A-1 preferred stock issued and outstanding and there were 43,649 shares of Series A-2 Preferred Stock
+Added: issued and outstanding.
The Series A-2, A-3, A-4, and A-5 Preferred Stock
3 unchanged sentences
on shares of Series A Preferred Stock equal (on an as-if-converted-to-common-stock basis) and in the same form as dividends(other than
−Removed: dividends in the form of common stock) actually paid on shares of the common stock when, as and if such dividends are paid on shares of
−Removed: the common stock.
+Added: dividends in the form of common stock) actually paid on shares of the common stock when, as and if such dividends are paid on shares
+Added: of the common stock.
Holders of the Series A-2, A-3,
13 unchanged sentences
to which the Investors surrendered all shares of Series A-2 Preferred Stock held by them in exchange for an aggregate of 21,388.01 shares
−Removed: of new preferred stock to be known as “Series A-2 Prime Preferred” (the “Exchanged Preferred”) having rights set
−Removed: forth the Amended and Restated Certificate of Designation of Preferences, Rights and Limitations of the Series A Convertible Voting Preferred
−Removed: Stock (the “Amended Series A Certificate of Designation”).
+Added: of new preferred stock to be known as “Series A-2 Prime Preferred” (the “Exchanged Preferred”) having rights
+Added: set forth the Amended and Restated Certificate of Designation of Preferences, Rights and Limitations of the Series A Convertible Voting
+Added: Preferred Stock (the “Amended Series A Certificate of Designation”).
Concurrent with execution of the Exchange Agreement,
16 unchanged sentences
Tranche A Warrants and the Amended Tranche B Warrants, the “Amended Warrants”).
−Removed: The Amended Warrants have the same terms and
−Removed: conditions as the original warrants except that such Amended Warrants:
−Removed: (i) reduced the amount of shares of Series A-3 Convertible Preferred
−Removed: Stock, Series A-4 Convertible Preferred Stock and Series A-5 Convertible Preferred Stock into which such Amended Warrants are convertible
−Removed: as described above;
−Removed: (ii) allow for the issuance of fractional shares of Series A-3 Preferred Stock, Series A-4 Preferred Stock and Series
−Removed: A-5 Preferred Stock, as applicable upon exercise of such Amended Warrants and (ii) revised the exercise price to be $ 1,000 per share of
−Removed: Series A-3 Preferred Stock, Series A-4 Preferred Stock and Series A-5 Preferred Stock, as applicable in such Amended Warrants.
−Removed: The aggregate
−Removed: exercise price, the amount of shares of common stock upon conversion of the Series A-3 Preferred Stock, the Series A-4 Preferred Stock
−Removed: and the Series A-5 Preferred Stock and exercise period in the Amended Warrants did not change from the Original Warrants.
+Added: The Amended Warrants have the same terms
+Added: and conditions as the original warrants except that such Amended Warrants:
+Added: (i) reduced the amount of shares of Series A-3 Convertible
+Added: Preferred Stock, Series A-4 Convertible Preferred Stock and Series A-5 Convertible Preferred Stock into which such Amended Warrants are
+Added: convertible as described above;
+Added: (ii) allow for the issuance of fractional shares of Series A-3 Preferred Stock, Series A-4 Preferred
+Added: Stock and Series A-5 Preferred Stock, as applicable upon exercise of such Amended Warrants and (ii) revised the exercise price to be
+Added: $ 1,000 per share of Series A-3 Preferred Stock, Series A-4 Preferred Stock and Series A-5 Preferred Stock, as applicable in such Amended
+Added: The aggregate exercise price, the amount of shares of common stock upon conversion of the Series A-3 Preferred Stock, the Series
+Added: A-4 Preferred Stock and the Series A-5 Preferred Stock and exercise period in the Amended Warrants did not change from the Original Warrants.
Pursuant to the terms of the Exchange Agreement,
10 unchanged sentences
At all times following
−Removed: the Issuance Date, while shares of Series A Preferred Stock are issued and outstanding, holders of Series A Preferred Stock shall be entitled
−Removed: to receive, and the Company shall pay, dividends on shares of Series A Preferred Stock equal (on an as-if-converted-to-common-stock
−Removed: basis and without regard to any limitations on conversion set forth herein or otherwise) to and in the same form as dividends (other than
−Removed: dividends in the form of common stock, which shall be made in accordance with the terms of the Amended Certificate of Designation) actually
−Removed: paid on shares of the common stock when, as and if such dividends (other than dividends in the form of common stock, which shall be made
−Removed: in accordance with the terms of the Amended Certificate of Designation) are paid on shares of the common stock.
+Added: the Issuance Date, while shares of Series A Preferred Stock are issued and outstanding, holders of Series A Preferred Stock shall be
+Added: entitled to receive, and the Company shall pay, dividends on shares of Series A Preferred Stock equal (on an as-if-converted-to-common-stock
+Added: basis and without regard to any limitations on conversion set forth herein or otherwise) to and in the same form as dividends (other
+Added: than dividends in the form of common stock, which shall be made in accordance with the terms of the Amended Certificate of Designation)
+Added: actually paid on shares of the common stock when, as and if such dividends (other than dividends in the form of common stock, which shall
+Added: be made in accordance with the terms of the Amended Certificate of Designation) are paid on shares of the common stock.
Voting Rights .
1 unchanged sentence
limitations described in the Amended Certificate of Designation, the Series A Preferred Stock is voting stock.
−Removed: Holders of the Series A
−Removed: Preferred Stock are entitled to vote together with the common stock on an as-if-converted-to-common-stock basis.
−Removed: Holders of common stock
−Removed: are entitled to one vote for each share of common stock held on all matters submitted to a vote of stockholders.
+Added: Holders of the Series
+Added: A Preferred Stock are entitled to vote together with the common stock on an as-if-converted-to-common-stock basis.
+Added: Holders of common
+Added: stock are entitled to one vote for each share of common stock held on all matters submitted to a vote of stockholders.
Accordingly, holders
2 unchanged sentences
Liquidation .
−Removed: Upon any Liquidation,
−Removed: the assets of the Company available for distribution to its stockholders shall be distributed among the holders of the shares of
−Removed: Series A Preferred Stock and common stock, pro rata based on the number of shares held by each such holder, treating for this
−Removed: purpose all shares of Series A Preferred Stock as if they had been converted to common stock pursuant to the terms of the Amended
−Removed: Certificate of Designation immediately prior to such Liquidation, without regard to any limitations on conversion set forth in the
−Removed: Amended Certificate of Designation or otherwise.
−Removed: Subject to the
−Removed: limitations set forth in the Amended Certificate of Designation, at the option of the holder, each share of Series A-2 Prime
−Removed: Preferred Stock, Series A-3 Convertible Preferred Stock, Series A-4 Convertible Preferred Stock or Series A-5 Convertible Preferred
−Removed: Stock shall be convertible into a number shares of common stock obtained by dividing the Original Per Share Price ($ 1,000 ) of each
−Removed: such share of Series A-2 Prime Convertible Preferred Stock, Series A-3 Convertible Preferred Stock, Series A-4 Convertible Preferred
−Removed: Stock or Series A-5 Convertible Preferred Stock by the applicable conversion price of $ 4.90 , $ 0.54 , $ 0.59 and $ 0.74 for the Series
−Removed: A-2 Prime Convertible Preferred Stock, Series A-3 Convertible Preferred Stock, Series A-4 Convertible Preferred Stock or Series A-5
−Removed: Convertible Preferred Stock, respectively.
−Removed: Pursuant to the terms of the Certificate of Correction to the Amended Series A
−Removed: Certificate of Designation filed on August 13, 2025 (which correction was effective as of March 14, 2024 pursuant to Section 103(f)
−Removed: of the Delaware General Corporation Law), there was no adjustment to the conversion prices for the Series A-3, A-4 and A-5 Preferred
−Removed: Stock as there were no shares outstanding in such series of preferred stock at the time of the reverse stock split.
+Added: Upon any Liquidation, the
+Added: assets of the Company available for distribution to its stockholders shall be distributed among the holders of the shares of Series A
+Added: Preferred Stock and common stock, pro rata based on the number of shares held by each such holder, treating for this purpose all shares
+Added: of Series A Preferred Stock as if they had been converted to common stock pursuant to the terms of the Amended Certificate of Designation
+Added: immediately prior to such Liquidation, without regard to any limitations on conversion set forth in the Amended Certificate of Designation
+Added: or otherwise.
+Added: Subject to the limitations
+Added: set forth in the Amended Certificate of Designation, at the option of the holder, each share of Series A-2 Prime Preferred Stock, Series
+Added: A-3 Convertible Preferred Stock, Series A-4 Convertible Preferred Stock or Series A-5 Convertible Preferred Stock shall be convertible
+Added: into a number shares of common stock obtained by dividing the Original Per Share Price ($ 1,000 ) of each such share of Series A-2 Prime
+Added: Convertible Preferred Stock, Series A-3 Convertible Preferred Stock, Series A-4 Convertible Preferred Stock or Series A-5 Convertible
+Added: Preferred Stock by the applicable conversion price of $ 4.90 , $ 0.54 , $ 0.59 and $ 0.74 for the Series A-2 Prime Convertible Preferred Stock,
+Added: Series A-3 Convertible Preferred Stock, Series A-4 Convertible Preferred Stock or Series A-5 Convertible Preferred Stock, respectively.
+Added: Pursuant to the terms of the Certificate of Correction to the Amended Series A Certificate of Designation filed on August 13, 2025 (which
+Added: correction was effective as of March 14, 2024 pursuant to Section 103(f) of the Delaware General Corporation Law), there was no adjustment
+Added: to the conversion prices for the Series A-3, A-4 and A-5 Preferred Stock as there were no shares outstanding in such series of preferred
+Added: stock at the time of the reverse stock split.
+Added: As of March 31, 2026, there were 2,265 shares of Series A-2 Prime Preferred Stock outstanding.
Issuance of Series B-1 Preferred Stock
10 unchanged sentences
2024, as corrected by the Certificate of Correction to Series B Certificate of Designation filed with the Delaware Secretary of State
−Removed: on November 8, 2024 (the “Series B Certificate of Designation”), each share of Series B-1 Preferred Stock is, subject to approval
−Removed: of the Company’s stockholders, convertible into shares of common stock of the Company and, if applicable, shares of Series B-2 Convertible
−Removed: Preferred Stock (the “Series B-2 Preferred Stock”), in lieu of common stock.
+Added: on November 8, 2024 (the “Series B Certificate of Designation”), each share of Series B-1 Preferred Stock is, subject to
+Added: approval of the Company’s stockholders, convertible into shares of common stock of the Company and, if applicable, shares of Series
+Added: B-2 Convertible Preferred Stock (the “Series B-2 Preferred Stock”), in lieu of common stock.
The Company has designated 50,000 shares of Series
1 unchanged sentence
The Series B Certificate of Designation states that, to the extent
−Removed: that the conversion of the Series B-1 preferred stock results in a beneficial ownership interest in excess of the maximum percentage of
−Removed: common stock upon conversion, the holders will receive them as converted equivalent for the remaining shares in preferred stock.
+Added: that the conversion of the Series B-1 preferred stock results in a beneficial ownership interest in excess of the maximum percentage
+Added: of common stock upon conversion, the holders will receive them as converted equivalent for the remaining shares in preferred stock.
On June 20, 2024, The Company held its annual
17 unchanged sentences
the Company shall pay, dividends on shares of Series B-1 Preferred Stock equal (on an as-if-converted-to-Common-Stock basis and without
−Removed: regard to any limitations on conversion set forth herein or otherwise) to and in the same form as dividends (other than dividends in the
−Removed: form of common stock, which shall be made in accordance with the terms of the Series B Certificate of Designation) actually paid on shares
−Removed: of the common stock when, as and if such dividends (other than dividends in the form of common stock, which shall be made in accordance
−Removed: with the terms of the Series B Certificate of Designation) are paid on shares of the common stock.
−Removed: Stockholder approval was received on
−Removed: June 20, 2024.
+Added: regard to any limitations on conversion set forth herein or otherwise) to and in the same form as dividends (other than dividends in
+Added: the form of common stock, which shall be made in accordance with the terms of the Series B Certificate of Designation) actually paid
+Added: on shares of the common stock when, as and if such dividends (other than dividends in the form of common stock, which shall be made in
+Added: accordance with the terms of the Series B Certificate of Designation) are paid on shares of the common stock.
+Added: Stockholder approval was
+Added: received on June 20, 2024.
Subject to certain limitations
9 unchanged sentences
calculation, any securities issued on the Signing Date) (the “Cap”), which each such holder being able to vote the number
−Removed: of shares of Series B Preferred Stock held by it relative to the total number of shares of Series B Preferred Stock then outstanding multiplied
−Removed: Notwithstanding the foregoing, the holders of the Series B Preferred Stock are not entitled to vote together with the common
−Removed: stock on an as-if-converted-to-Common-Stock-basis with regard to the approval of the issuance of common stock upon conversion of the Series
−Removed: B Preferred Stock.
+Added: of shares of Series B Preferred Stock held by it relative to the total number of shares of Series B Preferred Stock then outstanding
+Added: multiplied by the Cap.
+Added: Notwithstanding the foregoing, the holders of the Series B Preferred Stock are not entitled to vote together with
+Added: the common stock on an as-if-converted-to-Common-Stock-basis with regard to the approval of the issuance of common stock upon conversion
+Added: of the Series B Preferred Stock.
On the tenth trading day following the announcement
1 unchanged sentence
(1) the number
−Removed: of shares of common stock equal to the quotient of (A) the liquidation preference with respect to such share of Series B-1 Preferred Stock,
−Removed: divided by (B) the conversion price, provided that, to the extent the share conversion would cause such Holder’s beneficial ownership
−Removed: to exceed 9.99 %, such holder shall receive shares of Series B-2 Preferred Stock in lieu of common stock, on a one-for-one basis, with
−Removed: respect to the number of shares of common stock that exceed 9.99 % ownership divided by 1,000 .
+Added: of shares of common stock equal to the quotient of (A) the liquidation preference with respect to such share of Series B-1 Preferred
+Added: Stock, divided by (B) the conversion price, provided that, to the extent the share conversion would cause such Holder’s beneficial
+Added: ownership to exceed 9.99 %, such holder shall receive shares of Series B-2 Preferred Stock in lieu of common stock, on a one-for-one basis,
+Added: with respect to the number of shares of common stock that exceed 9.99 % ownership divided by 1,000 .
Liquidation Preference :
26 unchanged sentences
Subject to the limitations
−Removed: set forth in the Series B Certificate of Designation, at the option of the holder thereof, each share of Series B-2 Preferred Stock, is
−Removed: convertible into the number of shares of common stock equal to the quotient of (A) the stated value ($ 1,000 ), divided by (B) the conversion
+Added: set forth in the Series B Certificate of Designation, at the option of the holder thereof, each share of Series B-2 Preferred Stock,
+Added: is convertible into the number of shares of common stock equal to the quotient of (A) the stated value ($ 1,000 ), divided by (B) the conversion
price of $ 10.00 .
−Removed: As of September 30, 2025, all shares of Series B-2 Preferred Stock have been converted into common stock.
+Added: As of March 31, 2026, all shares of Series B-2 Preferred Stock have been converted into common stock.
Warrant Liability
−Removed: In connection with the Series A Preferred Stock Offering (see Note
−Removed: 8), the Company issued the Warrants.
+Added: In connection with the Series A Preferred Stock
+Added: Offering (see Note 9), the Company issued the Warrants.
After the Warrants were legally issued as a result
2 unchanged sentences
The Company determined that the Warrants, while initially contingently issuable, qualified as derivative instruments pursuant
−Removed: to ASC 815-40, Contracts in an Entity’s Own Equity and that the Warrants were considered issued for accounting purposes concurrently
−Removed: with the Series A-1 Preferred Stock.
+Added: to ASC 815-40, Contracts in an Entity’s Own Equity and that the Warrants were considered issued for accounting purposes
+Added: concurrently with the Series A-1 Preferred Stock.
On June 26, 2023, the Company held its annual
18 unchanged sentences
The significant unobservable inputs
−Removed: used in the fair value measurement of the Company’s Warrants include, but are not limited to, probability of obtaining certain shareholder
−Removed: approvals, probability of reaching certain technical milestones related to the development of Oxylanthanum Carbonate, and the estimated
−Removed: term of the Warrants.
−Removed: Significant increases (decreases) in any of those inputs in isolation would result in a significantly higher (lower)
−Removed: fair value measurement.
−Removed: Generally, a change in the assumption used for the probability of obtaining certain shareholder approvals is not
−Removed: correlated to a change in the probability of reaching certain technical milestones.
−Removed: However, a change to the assumption used for the probability
−Removed: of obtaining certain shareholder approvals or a change in the probability of reaching certain technical milestones would have been accompanied
−Removed: by a directionally opposite change and a directionally similar change, respectively, in the assumption used for the estimated term.
+Added: used in the fair value measurement of the Company’s Warrants include, but are not limited to, probability of obtaining certain
+Added: shareholder approvals, probability of reaching certain technical milestones related to the development of oxylanthanum carbonate, and
+Added: the estimated term of the Warrants.
+Added: Significant increases (decreases) in any of those inputs in isolation would result in a significantly
+Added: higher (lower) fair value measurement.
+Added: Generally, a change in the assumption used for the probability of obtaining certain shareholder
+Added: approvals is not correlated to a change in the probability of reaching certain technical milestones.
+Added: However, a change to the assumption
+Added: used for the probability of obtaining certain shareholder approvals or a change in the probability of reaching certain technical milestones
+Added: would have been accompanied by a directionally opposite change and a directionally similar change, respectively, in the assumption used
+Added: for the estimated term.
The fair value of the Warrants associated with
4 unchanged sentences
(i) the threshold of exercising the warrant, (ii) the price
−Removed: of the underlying security, (iii) the time to expiration, or expected term, (iv) the expected volatility of the underlying security, (v)
−Removed: the risk-free rate, (vi) the number of paths, (vii) estimated probability assumptions surrounding shareholder approval as well as the
−Removed: achievement by the Company of technical milestones associated with regulatory and commercial progress, and (viii) an estimated discount
+Added: of the underlying security, (iii) the time to expiration, or expected term, (iv) the expected volatility of the underlying security,
+Added: (v) the risk-free rate, (vi) the number of paths, (vii) estimated probability assumptions surrounding shareholder approval as well as
+Added: the achievement by the Company of technical milestones associated with regulatory and commercial progress, and (viii) an estimated discount
for lack of marketability.
5 unchanged sentences
the exercise price for the Warrants became fixed.
−Removed: Therefore, as of December 31, 2024 and September 30, 2025, the fair value of the Warrants
+Added: Therefore, as of December 31, 2024 and December 31, 2025, the fair value of the Warrants
was determined using a Black Scholes model using parameters including (i) the exercise price of the warrant, (ii) the price of the underlying
−Removed: security, (iii) the time to expiration, or expected term, (iv) the expected volatility of the underlying security, (v) the risk-free rate,
−Removed: and (vi) estimated probability assumptions surrounding the achievement by the Company of technical milestones associated with regulatory
−Removed: and commercial progress.
+Added: security, (iii) the time to expiration, or expected term, (iv) the expected volatility of the underlying security, (v) the risk-free
+Added: rate, (vi) discount for lack of marketability, and (vii) estimated probability assumptions surrounding the achievement by the Company
+Added: of technical milestones associated with regulatory and commercial progress.
These valuation techniques involve management’s
estimates and judgment based on unobservable inputs and are classified in Level 3.
−Removed: The fair value estimates may not be indicative of the
−Removed: amounts that would be realized in a market exchange.
−Removed: Additionally, there may be inherent uncertainties or changes in the underlying assumptions
−Removed: used, which could significantly affect the current or future fair value estimates.
−Removed: Generally, a significant increase (decrease) in the
−Removed: probabilities of shareholder approval and the achievement of technical milestones would have resulted in a significantly higher (lower)
−Removed: fair value measurement;
−Removed: however, changes in other inputs such as expected term and price of the underlying common stock will have a directionally
−Removed: opposite impact on fair value measurement.
+Added: The fair value estimates may not be indicative of
+Added: the amounts that would be realized in a market exchange.
+Added: Additionally, there may be inherent uncertainties or changes in the underlying
+Added: assumptions used, which could significantly affect the current or future fair value estimates.
+Added: Generally, a significant increase (decrease)
+Added: in the probabilities of shareholder approval and the achievement of technical milestones would have resulted in a significantly higher
+Added: (lower) fair value measurement;
+Added: however, changes in other inputs such as expected term and price of the underlying common stock will
+Added: have a directionally opposite impact on fair value measurement.
The Company uses a third-party valuation expert
1 unchanged sentence
The tables below summarize the valuation inputs into the Black Scholes
−Removed: model for the liability associated with the three tranches of Warrants at December 31, 2024 and September 30, 2025.
+Added: model for the liability associated with the three tranches of Warrants at December 31, 2025 and March 31, 2026.
Tranche A Warrant
−Removed: September 30,
Fair value of underlying stock
11 unchanged sentences
Tranche B Warrant
−Removed: September 30,
Fair value of underlying stock
6 unchanged sentences
Discount for lack of marketability
−Removed: Probability for receipt of Transitional Drug Add-On Payment Adjustment approval for Oxylanthanum Carbonate
+Added: Probability for receipt of Transitional Drug Add-On Payment
+Added: Adjustment approval for Oxylanthanum carbonate
Tranche C Warrant
−Removed: September 30,
Fair value of underlying stock
3 unchanged sentences
Risk free rate
−Removed: 3.6 % - 3.7 %
Dividend yield
1 unchanged sentence
Discount for lack of marketability
−Removed: Probability for public disclosure of financial results for four (4) quarters of commercial sales for Oxylanthanum Carbonate following receipt of Transitional Drug Add-On Payment Adjustment approval
+Added: Probability for public disclosure of financial results
+Added: for four (4) quarters of commercial sales for Oxylanthanum carbonate following receipt of Transitional Drug Add-On Payment Adjustment
1.56 % - 51.2 %
2.7 % - 61.41 %
−Removed: As of the issuance date (March 3, 2023), the Company
−Removed: estimated the fair value of the Warrants to be $ 2.8 million.
−Removed: As of December 31, 2024 and September 30, 2025, the Company estimated the
−Removed: fair value of the Warrants to be $ 18.9 million and $ 9.1 million, respectively.
+Added: As of the issuance date (March 3, 2023), the
+Added: Company estimated the fair value of the Warrants to be $ 2.8 million.
+Added: As of December 31, 2025 and March 31, 2026, the Company estimated
+Added: the fair value of the Warrants to be $ 16.9 million and $ 21.7 million, respectively.
The following table summarizes activity, on an
−Removed: as-converted to common shares basis, for the Company’s preferred stock warrants for the nine months ended September 30, 2025:
+Added: as-converted to common shares basis, for the Company’s preferred stock warrants for the three months ended March 31, 2026:
Number of Average
6 unchanged sentences
Warrants exercised -
−Removed: Outstanding, September 30, 2025 15,818,817 $ 6.42 1.37 $ -
+Added: Outstanding, March 31, 2026 15,818,817 $ 6.41 0.88 $ -
Stock-based Compensation
7 unchanged sentences
award agreements.
−Removed: A total of 130,233 shares of common stock were reserved for issuance pursuant to the 2021 Plan prior to our annual meeting
−Removed: on June 26, 2023.
+Added: A total of 130,233 shares of common stock were reserved for issuance pursuant to the 2021 Plan prior to our annual
+Added: meeting on June 26, 2023.
Shareholders approved an increase to the number of shares reserved on June 26, 2023, and accordingly, at December
2 unchanged sentences
shares, to the number of shares reserved, for a total of 2,077,600 shares.
−Removed: On January 1, 2025, , pursuant to an evergreen increase provision
−Removed: in the 2021 Plan, the amount of shares reserved under the Plan increased by 1,235,316 shares, to the number of shares reserved,
−Removed: for a total of 3,312,916 shares.
−Removed: The 2021 Plan provides for the issuance of incentive stock options, non-statutory stock options,
−Removed: stock appreciation rights, restricted stock, restricted stock units, and other stock-based awards.
−Removed: As of December 31, 2024, approximately
−Removed: 743,333 shares of common stock were available under the 2021 Plan.
−Removed: As of September 30, 2025, there are approximately 1,310,150 shares
−Removed: of common stock available under the 2021 Plan.
+Added: On January 1, 2025, pursuant to a 4 % evergreen increase provision
+Added: in the 2021 Plan, the amount of shares reserved under the Plan increased by 1,235,316 shares, to the number of shares reserved, for a
+Added: total of 3,312,916 shares.
+Added: The 2021 Plan provides for the issuance of incentive stock options, non-statutory stock options, stock appreciation
+Added: rights, restricted stock, restricted stock units, and other stock-based awards.
+Added: As of March 31, 2025, approximately 1,967,649 shares
+Added: of common stock were available under the 2021 Plan.
+Added: As of March 31, 2026, there are approximately 2,194,720 shares of common stock available
+Added: under the 2021 Plan.
+Added: On January 1, 2026, pursuant to a 4 % evergreen increase provision in the 2021 Plan, the amount of shares reserved
+Added: under the Plan increased by 884,570 shares, to the number of shares reserved, for a total of 4,197,486 shares.
The following table summarizes activity for stock
−Removed: options under all plans for the nine months ended September 30, 2025:
+Added: options under all plans for the three months ended March 31, 2026:
Number of Average
7 unchanged sentences
Options exercised -
−Removed: Outstanding, September 30, 2025 2,033,114 $ 8.31 8.48 $ 7,509
−Removed: Options vested and exercisable as of September 30, 2025 816,875 $ 11.04 7.35 $ 2,705
−Removed: The grant date fair value of options granted during the nine months
−Removed: ended September 30, 2025, was approximately $ 2.8 million .
−Removed: As of September 30, 2025, the unrecognized compensation
+Added: Outstanding, March 31, 2026 2,033,114 $ 8.31 7.99 $ 11,862
+Added: Options vested and exercisable as of March 31, 2026 976,013 $ 10.51 6.93 $ 5,344
+Added: The grant date fair value of options granted
+Added: during the three months ended March 31, 2026, was approximately $ 14.4 million.
+Added: As of March 31, 2026, the unrecognized compensation
cost related to outstanding stock options was $ 4.9 million, which is expected to be recognized as expense over approximately 3.3 years.
2 unchanged sentences
A portion of these options were
−Removed: exercised early (prior to vesting), and as of September 30, 2024, none of the options remained unvested.
+Added: exercised early (prior to vesting), and as of December 31, 2024, none of the options remained unvested.
Proceeds received related to
17 unchanged sentences
The Company has recorded stock-based compensation
−Removed: expense, which includes expense related to restricted stock units, allocated by functional cost as follows for the three and nine months
−Removed: ended September 30, 2024 and 2025 (in thousands):
+Added: expense, which includes expense related to restricted stock units, allocated by functional cost as follows for the three months ended
+Added: March 31, 2025 and 2026 (in thousands):
Three Months Ended
−Removed: Nine months ended
−Removed: September 30,
−Removed: September 30,
+Added: Three Months Ended
Research and development
13 unchanged sentences
fair value of the common stock underlying the Company’s stock options prior to the initial public offering was estimated at each
−Removed: grant date and was determined on a periodic basis and based either on transactions with third parties in which common stock was sold for
−Removed: cash or with the assistance of an independent third-party valuation expert.
+Added: grant date and was determined on a periodic basis and based either on transactions with third parties in which common stock was sold
+Added: for cash or with the assistance of an independent third-party valuation expert.
Subsequent to our initial public offering, the fair value
1 unchanged sentence
The assumptions
−Removed: underlying these valuations represented management’s best estimates, which involved inherent uncertainties and the application of
−Removed: significant levels of management judgment.
+Added: underlying these valuations represented management’s best estimates, which involved inherent uncertainties and the application
+Added: of significant levels of management judgment.
Volatility - The expected volatility
3 unchanged sentences
risk-free interest rate is based on median U.S.
−Removed: Treasury zero coupon issues with remaining terms similar to the expected term on the options.
+Added: Treasury zero coupon issues with remaining terms similar to the expected term on the
Expected Dividend – Through
−Removed: September 30, 2025, the Company has never declared nor paid any cash dividends on common stock.
−Removed: The Company shall modify its dividend
−Removed: policy to state that the Company intends to pay dividends to all stockholders, including holders of Series A Preferred Stock on an as-if-converted-to-common-stock
+Added: March 31, 2026, the Company has never declared nor paid any cash dividends on common stock.
+Added: The Company shall modify its dividend policy
+Added: to state that the Company intends to pay dividends to all stockholders, including holders of Series A Preferred Stock on an as-if-converted-to-common-stock
basis, on a quarterly basis in an amount of which the aggregate of all quarterly dividends shall equal at least seventy-five percent
1 unchanged sentence
of commercial sales.
−Removed: The following averaged assumptions were used to
−Removed: calculate the fair value of awards granted to employees, directors and non-employees for the three months ended September 30, 2024 and
−Removed: September 30, 2025:
−Removed: Nine months ended
−Removed: September 30,
+Added: The following averaged assumptions were used
+Added: to calculate the fair value of awards granted to employees, directors and non-employees for the three months ended March 31, 2025 and
+Added: March 31, 2026:
+Added: Three Months Ended
+Added: 2025 Three Months Ended
Expected volatility 108.49 % 107.44 % - 116.54 %
−Removed: 107.44 % - 116.14 %
Risk-free interest rate 4.38 % 3.75 % - 4.38 %
−Removed: 3.77 % - 4.65 %
−Removed: 3.75 % - 4.38 %
Dividend yield - % - %
−Removed: Expected term
+Added: Expected term 6.25 years 5.50 years - 6.25 years
Net Income (Loss) Per Share
1 unchanged sentence
using the two-class method.
−Removed: The two-class method uses an earnings allocation formula that determines net income (loss) per share for common
−Removed: stock and any participating securities according to dividends declared and participation rights in undistributed earnings.
−Removed: Diluted net income (loss) per share includes the
−Removed: potential dilutive effect of common stock equivalents as if such securities were converted or exercised during the period, when the effect
+Added: The two-class method uses an earnings allocation formula that determines net income (loss) per share for
+Added: common stock and any participating securities according to dividends declared and participation rights in undistributed earnings.
+Added: Diluted net income (loss) per share includes
+Added: the potential dilutive effect of common stock equivalents as if such securities were converted or exercised during the period, when the
+Added: effect is dilutive.
Common stock equivalents include:
(i) outstanding stock options and restricted stock units;
−Removed: (ii) common stock to be issued
−Removed: upon the assumed exercise of the Company’s common stock warrants;
+Added: (ii) common stock to
+Added: be issued upon the assumed exercise of the Company’s common stock warrants;
(iii) convertible preferred stock;
−Removed: and (iv) prior to issuance,
−Removed: the issuable warrants related to the Company’s March 2023 private placement financing.
+Added: and (iv) prior to
+Added: issuance, the issuable warrants related to the Company’s March 2023 private placement financing.
The following table sets forth the computation
1 unchanged sentence
Three Months Ended
−Removed: September 30,
−Removed: Nine Months Ended
−Removed: September 30,
−Removed: Basic net loss per share
−Removed: Cash Dividends to Series B holders
−Removed: Net loss attributable to common shares, basic and diluted
−Removed: Weighted-average shares outstanding used in computing net loss per share attributable to common stockholders, basic and diluted
−Removed: Net loss per share attributable to common stockholders, basic and diluted
+Added: Basic net (loss) income per share
+Added: Net income (loss)
+Added: Dividend to Series B preferred stockholders
+Added: Net income attributable to participating securities
+Added: Net income (loss) attributable to common stockholders, basic
+Added: Weighted-average shares outstanding used in computing net income (loss) per share attributable to common stockholders, basic
+Added: Net income (loss) per share attributable to common stockholders, basic
+Added: Three Months Ended
+Added: Diluted net loss per share
+Added: Net income (loss)
+Added: Net income attributable to participating securities
+Added: Change in fair value of preferred stock warrant liability
+Added: Net loss attributable to common stockholders, diluted
+Added: Weighted-average shares outstanding used in computing net
+Added: loss per share attributable to common stockholders, diluted
+Added: Net loss per share attributable to common stockholders, diluted
The following outstanding shares of potentially
2 unchanged sentences
Three Months Ended
−Removed: September 30,
−Removed: Nine Months Ended
−Removed: September 30,
+Added: Three Months Ended
Options to purchase common stock
5 unchanged sentences
Subsequent Events
−Removed: Subsequent to September 30, 2025, pursuant to a sales agreement dated
−Removed: November 13, 2024 with Guggenheim Securities, LLC, Unicycive Therapeutics, Inc.
−Removed: (the “Company”) sold 641,033 shares of common
−Removed: stock at an average price of $ 4.78 per share, resulting in net proceeds to the Company of approximately $ 3.0 million.
+Added: Subsequent to March 31, 2026, pursuant to a sales
+Added: agreement dated November 13, 2024 between the Company and Guggenheim Securities, LLC, as amended by Amendment No.
+Added: 1 thereto dated November
+Added: 14, 2025, the Company sold 1,000,000 shares of common stock at an average price of $ 6.45 per share, resulting in net proceeds to the
+Added: Company of approximately $ 6.3 million.
Compared sentence by sentence after normalising whitespace, quotation marks, case and digits, so re-formatting and restated figures do not read as changed language. Wording changes appear as one removal and one addition. The current filing and the prior one are authoritative.