1 unchanged sentence
Securities Trading Plans of Directors and Executive Officers
−Removed: During the three months ended June 30, 2025, none of our directors or executive officers adopted or terminated any contract , instruction or written plan for the purchase or sale of our securities that was intended to satisfy the affirmative defense conditions of Rule 10b5-1(c) or any “non-Rule 10b5-1 trading arrangement” as defined in Item 408 of Regulation S-K under the Securities Exchange Act of 1934, as amended.
+Added: During the three months ended September 30, 2025, none of our directors or executive officers adopted or terminated any contract , instruction or written plan for the purchase or sale of our securities that was intended to satisfy the affirmative defense conditions of Rule 10b5-1(c) or any “non-Rule 10b5-1 trading arrangement” as defined in Item 408 of Regulation S-K under the Securities Exchange Act of 1934, as amended.
The exhibits listed on the accompanying index to exhibits are filed or incorporated by reference (as stated therein) as part of this Quarterly Report on Form 10-Q.
8 unchanged sentences
Rigel Pharmaceuticals, Inc.
−Removed: 2018 Equity Incentive Plan, as amended .
−Removed: Rigel Pharmaceuticals, Inc.
−Removed: Inducement Plan, as amended .
+Added: Inducement Plan, as amended (filed as an exhibit to Rigel’s Quarterly Report on Form 10-Q for the quarter ended June 30, 2025 file on August 5, 2025 and incorporated herein by reference).
+Added: First Amendment to Lease Agreement with 611 Gateway Center LP, dated August 20, 2025.
+Added: Amendment No.
+Added: 3 to the License and Collaboration Agreement with Eli Lilly and Company, dated August 28, 2025 .
Certification required by Rule 13a-14(a) or Rule 15d-14(a) of the Exchange Act.
10 unchanged sentences
Indicates a management contract or compensatory plan or arrangement.
+Added: ˄ Certain marked information has been omitted from this exhibit because it is both not material and is the type that the registrant treats as private and confidential.
* The certifications attached as Exhibit 32.1 accompany this Quarterly Report on Form 10-Q pursuant to 18 U.S.C.
4 unchanged sentences
(Principal Executive Officer)
−Removed: August 5, 2025
+Added: November 4, 2025
Chief Financial Officer
(Principal Financial Officer)
−Removed: August 5, 2025
+Added: November 4, 2025
Compared sentence by sentence after normalising whitespace, quotation marks, case and digits, so re-formatting and restated figures do not read as changed language. Wording changes appear as one removal and one addition. The current filing and the prior one are authoritative.