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On July 26, 2022 and July 28, 2022, securities class action complaints (the former, the “Chow Action” and the latter, the
−Removed: “Manici Action”) and together, the “Securities Class Action Litigation”) were filed by purported stockholders
−Removed: of the Company in the United States District Court for the Central District of California against the Company and certain of the Company’s
−Removed: current and former officers and directors.
−Removed: The complaints allege, among other things, that the defendants violated Sections 10(b) and
−Removed: 20(a) of the Securities Exchange Act of 1934, as amended, and Rule 10b-5 thereunder, by making false and misleading statements and omissions
−Removed: of material fact in connection with the Company’s relationship with Serhat Gümrükcü and its commercial prospects.
+Added: “Manici Action”) were filed by purported stockholders of the Company in the United States District Court for the Central District
+Added: of California against the Company and certain of the Company’s current and former officers and directors.
+Added: The complaints allege,
+Added: among other things, that the defendants violated Sections 10(b) and 20(a) of the Securities Exchange Act of 1934, as amended, and Rule
+Added: 10b-5 thereunder, by making false and misleading statements and omissions of material fact in connection with the Company’s relationship
+Added: with Serhat Gümrükcü and its commercial prospects.
The complaints seek unspecified damages, interest, fees, and costs.
−Removed: On November 22, 2022, the Manici Action was voluntarily dismissed
−Removed: without prejudice, but the Chow action remains pending.
+Added: On November 22, 2022, the Manici Action was voluntarily dismissed without prejudice.
+Added: The Chow Action (also referred to as the “Securities
+Added: Class Action Litigation”) remains pending.
On October 22, 2023, the Court appointed a lead plaintiff in the Chow Action.
−Removed: The lead plaintiff filed an amended complaint on December 15, 2023.
+Added: plaintiff filed an amended complaint on December 15, 2023.
The Company filed a motion to dismiss the amended complaint on March 15, 2024.
The Court denied the Company’s motion to dismiss on June 28, 2024.
−Removed: A mediation was held on September 17, 2024, after which
−Removed: the parties signed a stipulation of settlement, dated November 8, 2024.
−Removed: The plaintiff filed their motion for preliminary approval of the
−Removed: settlement on December 9, 2024.
−Removed: On December 18, 2024, the Company filed a notice of non-opposition to the motion for preliminary approval
−Removed: of the settlement.
−Removed: On January 7, 2025, the Court took the plaintiff’s motion for preliminary approval of the settlement under consideration
−Removed: without oral argument.
−Removed: Federal Derivative
+Added: A mediation was held on September 17, 2024, after which the parties
+Added: signed a stipulation of settlement that, subject to final approval by the United States District Court for the Central District of California,
+Added: provides for resolution of the Securities Class Action Litigation.
+Added: The Court granted the lead plaintiff’s motion for preliminary
+Added: approval of the settlement on August 18, 2025.
+Added: Federal Derivative Litigation.
On September 22, 2022, Samuel E.
−Removed: Koenig filed a shareholder derivative action in the United States District Court
−Removed: for the Central District of California (the “Koenig Matter”).
−Removed: On January 19, 2023, John Solak filed a substantially
−Removed: similar shareholder derivative action in the United States District Court for the District of Delaware (the “Solak
−Removed: Both derivative actions recite similar underlying facts as those alleged in the Securities Class Action Litigation.
−Removed: The actions, filed on behalf of the Company, name Serhat Gümrükcü and certain of the Company’s former directors
−Removed: as defendants.
−Removed: The actions also name the Company as a nominal defendant.
−Removed: The actions allege violations of Sections 14(a) and 20(a)
−Removed: of the Securities Exchange Act of 1934 and also set out claims for breach of fiduciary duty, contribution and indemnification,
−Removed: aiding and abetting, and gross mismanagement.
−Removed: Plaintiffs do not quantify any alleged injury, but seek damages, disgorgement,
−Removed: restitution, and other costs and expenses.
−Removed: On January 24, 2023, the United States District Court for the Central District of
−Removed: California stayed the Koenig Matter pending resolution of the defendants’ anticipated motion to dismiss in the Securities
−Removed: Class Action Litigation.
−Removed: On April 4, 2023, the United States District Court for the District of Delaware stayed the Solak Matter
−Removed: pending resolution of the defendants’ anticipated motion to dismiss in the Securities Class Action Litigation.
−Removed: 2024, the United States District Court for the Central District of California denied the defendants’ motion to dismiss the
−Removed: Securities Class Action Litigation.
−Removed: The Koenig Matter is currently stayed and the parties’ deadline to file a joint status
−Removed: report is July 11, 2025.
−Removed: On April 30, 2025, the court stayed the Solak Matter for ninety (90) days and the deadline for the parties
−Removed: to file a joint status report or further stay of the action is July 29, 2025.
−Removed: The defendants have not yet responded to the Koenig or
−Removed: Solak complaints.
−Removed: The Company intends to contest these matters but expresses no opinion as to the likelihood of favorable outcomes.
−Removed: Management is unable to determine the likelihood of a loss, including a possible range of losses, if any, arising from this matter
−Removed: as of the reporting date.
+Added: Koenig filed a shareholder derivative action in the United States District Court for the Central
+Added: District of California (the “Koenig Matter”).
+Added: The Koenig Matter, filed on behalf of the Company, names Serhat Gümrükcü
+Added: and certain of the Company’s current and former directors as defendants, and also names the Company as a nominal defendant.
+Added: Koenig Matter alleges violations of Sections 14(a) and 20(a) of the Securities Exchange Act of 1934, and also sets out claims for breach
+Added: of fiduciary duty, contribution and indemnification, aiding and abetting, and gross mismanagement.
+Added: Plaintiff does not quantify any alleged
+Added: injury, but seeks damages, disgorgement, restitution, and other costs and expenses.
+Added: On January 24, 2023, the United States District Court
+Added: for the Central District of California stayed the Koenig Matter pending resolution of the defendants’ anticipated motion to dismiss
+Added: in the Securities Class Action Litigation.
+Added: On June 28, 2024, the United States District Court for the Central District of California denied
+Added: defendants’ motion to dismiss the Securities Class Action Litigation.
+Added: The parties in the Koenig Matter, the Solak Matter (defined
+Added: below), and the Midler Matter (defined below) have entered into a stipulation of settlement that, subject to final approval by the United
+Added: States District Court for the Central District of California, provides for resolution of the Koenig Matter, Solak Matter, and Midler Matter
+Added: (the “Koenig-Solak-Midler Settlement”).
+Added: On November 3, 2025, plaintiff in the Koenig Matter filed a motion for preliminary
+Added: approval of the Koenig-Solak-Midler Settlement with the United States District Court for the Central District of California.
+Added: The defendants
+Added: have not yet responded to the complaint.
+Added: On January 19, 2023, John Solak
+Added: filed a shareholder derivative action in the United States District Court for the District of Delaware (the “Solak Matter”).
+Added: The Solak Matter, filed on behalf of the Company, names Serhat Gümrükcü and certain of the Company’s current and
+Added: former directors as defendants, and also names the Company as a nominal defendant.
+Added: The Solak Matter alleges violations of Section 14(a)
+Added: of the Securities Exchange Act of 1934 and SEC Rule 14a-9 promulgated thereunder, and also sets out claims for breach of fiduciary duty
+Added: and contribution and indemnification.
+Added: Plaintiff does not quantify any alleged injury, but seeks damages, disgorgement, restitution, and
+Added: other costs and expenses.
+Added: On April 6, 2023, the United States District Court for the District of Delaware stayed the Solak Matter pending
+Added: resolution of the defendants’ anticipated motion to dismiss in the Securities Class Action Litigation.
+Added: On June 28, 2024, the United
+Added: States District Court for the Central District of California denied defendants’ motion to dismiss the Securities Class Action Litigation.
+Added: On November 3, 2025, plaintiff in the Koenig Matter filed a motion for preliminary approval of the Koenig-Solak-Midler Settlement in the
+Added: United States District Court for the Central District of California.
+Added: The Solak Matter is stayed pending approval of the Koenig-Solak-Midler
+Added: The defendants have not yet responded to the complaint.
+Added: Management is unable to determine the likelihood of a loss, including
+Added: a possible range of losses, if any, arising from this matter as of the reporting date.
State Derivative Litigation.
−Removed: On October 20, 2022, Susan Midler filed a shareholder derivative action in the Superior Court of California, Los Angeles County, reciting
−Removed: similar underlying facts as those alleged in the Securities Class Action Litigation (the “Midler Matter”).
−Removed: The action, filed
−Removed: on behalf of the Company, names Serhat Gümrükcü and certain of the Company’s current and former directors as defendants.
−Removed: The action also names the Company as a nominal defendant.
−Removed: The action sets out claims for breaches of fiduciary duty, contribution and
−Removed: indemnification, aiding and abetting, and gross mismanagement.
−Removed: Plaintiff does not quantify any alleged injury, but seeks damages, disgorgement,
−Removed: restitution, and other costs and expenses.
−Removed: On January 20, 2023, the Court stayed the Midler matter pending resolution of the defendants’
−Removed: anticipated motion to dismiss in the Securities Class Action Litigation.
−Removed: On June 28, 2024, the United States District Court for the Central
−Removed: District of California denied the defendants’ motion to dismiss the Securities Class Action Litigation.
−Removed: On April 29, 2025, the court
−Removed: stayed the Midler Matter for ninety (90) days.
−Removed: The parties’ deadline to file a joint status report in the Midler action is July
+Added: On October 20, 2022, Susan Midler filed a shareholder derivative action in the Superior Court of California, Los Angeles County (the “Midler
+Added: The Midler Matter, filed on behalf of the Company, names Serhat Gümrükcü and certain of the Company’s
+Added: current and former directors as defendants.
+Added: The Midler Matter also names the Company as a nominal defendant.
+Added: The Midler Matter sets out
+Added: claims for breaches of fiduciary duty, contribution and indemnification, aiding and abetting, and gross mismanagement.
+Added: Plaintiff does
+Added: not quantify any alleged injury, but seeks damages, disgorgement, restitution, and other costs and expenses.
+Added: On January 20, 2023, the
+Added: Court stayed the Midler Matter pending resolution of the defendants’ anticipated motion to dismiss in the Securities Class Action
+Added: On June 28, 2024, the United States District Court for the Central District of California denied defendants’ motion
+Added: to dismiss the Securities Class Action Litigation.
+Added: On July 31, 2025, the court stayed the Midler Matter for 120 days.
+Added: On November 3, 2025,
+Added: plaintiff in the Koenig Matter filed a motion for preliminary approval of the Koenig-Solak-Midler Settlement in the United States District
+Added: Court for the Central District of California.
The defendants have not yet responded to the complaint.
−Removed: The Company intends to contest this matter but expresses no opinion
−Removed: as to the likelihood of a favorable outcome.
−Removed: Management is unable to determine the likelihood of a loss, including a possible range of
−Removed: losses, if any, arising from this matter as of the reporting date.
+Added: Management is unable to determine
+Added: the likelihood of a loss, including a possible range of losses, if any, arising from this matter as of the reporting date.
21, 2022, the Company filed a Complaint in the Superior Court of the State of California for the County of Los Angeles against Serhat
−Removed: Gümrükcü, William Anderson Wittekind (“Wittekind”), G Tech Bio, SG & AW Holdings, LLC, and SRI (collectively,
−Removed: the “Defendants”).
−Removed: The Complaint alleges that the Defendants engaged in a “concerted, deliberate scheme to alter, falsify,
−Removed: and misrepresent to the Company the results of multiple studies supporting its Hepatitis B and SARS-CoV-2/influenza pipelines.”
−Removed: Specifically, “Defendants manipulated negative results to reflect positive outcomes from various studies, and even fabricated studies
−Removed: out of whole cloth.” As a result of the Defendants’ conduct, the Company claims that it “paid approximately $25 million
−Removed: to Defendants and third-parties that it would not otherwise have paid.” On April 21, 2023, defendants Wittekind, G Tech, SG &
−Removed: AW Holdings, LLC, and SRI filed a demurrer with respect to some, but not all, of the Company’s claims, as well as a motion to strike.
+Added: Gümrükcü (“Gumrukcu”), William Anderson Wittekind (“Wittekind”), G Tech Bio, SG & AW Holdings,
+Added: LLC, and SRI (collectively, the “Defendants”).
+Added: The Complaint alleges that the Defendants engaged in a “concerted, deliberate
+Added: scheme to alter, falsify, and misrepresent to the Company the results of multiple studies supporting its Hepatitis B and SARS-CoV-2/influenza
+Added: pipelines.” Specifically, “Defendants manipulated negative results to reflect positive outcomes from various studies, and
+Added: even fabricated studies out of whole cloth.” As a result of the Defendants’ conduct, the Company claims that it “paid
+Added: approximately $25 million to Defendants and third-parties that it would not otherwise have paid.” On April 21, 2023, defendants
+Added: Wittekind, G Tech, SG & AW Holdings, LLC, and SRI filed a demurrer with respect to some, but not all, of the Company’s claims,
+Added: as well as a motion to strike.
On September 6, 2023, the court denied in part and granted in part the pending motions.
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as of April 18, 2021, have been terminated and the Company has no rights to any license under such agreements.
−Removed: was scheduled to begin on March 3, 2025.
−Removed: On November 14, 2024, the court vacated the March 3, 2025 trial date and set a trial setting
−Removed: conference for May 1, 2025.
+Added: Trial was scheduled to
+Added: begin on March 3, 2025.
+Added: On November 14, 2024, the court vacated the March 3, 2025, trial date and set a trial setting conference for May
At the May 1, 2025, trial setting conference, the court reset the trial to begin on November 30, 2026.
−Removed: remains ongoing.
−Removed: The Company denies the allegations in Defendants’ cross claims and intends to vigorously defend against them while
−Removed: pursuing its claims against the Defendants.
−Removed: 1, 2021, the Company’s former Chief Financial Officer, Robert Wolfe and his company, Crossfield, Inc., filed a Complaint in the
−Removed: District Court for the District of Vermont against the Company, Renovaro Biosciences Denmark ApS, and certain directors and officers.
−Removed: In the Complaint, Mr.
−Removed: Wolfe and Crossfield, Inc.
−Removed: asserted claims for abuse of process and malicious prosecution, alleging, inter alia,
−Removed: that the Company lacked probable cause to file and prosecute an earlier action, and sought millions of dollars of compensatory damages,
−Removed: as well as punitive damages.
−Removed: The allegations in the Complaint relate to an earlier action filed by the Company and Renovaro Biosciences
−Removed: Denmark ApS in the Vermont Superior Court, Orange Civil Division.
−Removed: On March 3, 2022, the court partially granted the Company’s motion
−Removed: to dismiss, dismissing the abuse of process claim against all defendants and all claims against Mark Dybul and Henrik Grønfeldt-Sørensen,
−Removed: the Company’s former Chief Executive Officer and former member of the Board of Directors, respectively.
−Removed: On November 29, 2022, the
−Removed: Company filed a motion for summary judgment with respect to the sole remaining claim of malicious prosecution.
−Removed: On August 24, 2023, the
−Removed: court denied the motion for summary judgment.
−Removed: about April 16, 2025, the parties entered into a confidential settlement agreement.
−Removed: The confidential settlement agreement requires certain
−Removed: events to occur within 45 days and 60 days and, accordingly, the court has entered a 65-day dismissal nisi.
−Removed: Unless a party moves to reopen
−Removed: within the 65-day period, the action will be dismissed with prejudice.
−Removed: On June 7, 2023, Weird Science
−Removed: LLC (“Weird Science”), Wittekind, the William Anderson Wittekind 2020 Annuity Trust, the William Anderson Wittekind 2021 Annuity
−Removed: Trust, the Dybul 2020 Angel Annuity Trust, and the Ty Mabry 2021 Annuity Trust (collectively, the “Trusts”) (collectively,
−Removed: “Plaintiffs”) filed a Verified Complaint against the Company in the Court of Chancery of Delaware.
−Removed: In the Verified Complaint,
−Removed: Plaintiffs alleged that the Company breached the February 16, 2018 Investor Rights Agreement between the Company, Weird Science, and RS
−Removed: Group ApS (the “Investor Rights Agreement”).
−Removed: According to the Verified Complaint, the Investor Rights Agreement required the
−Removed: Company to (i) notify all “Holders” of “Registrable Securities” at least 30 days prior to filing a registration
+Added: Discovery remains ongoing.
+Added: The Company denies the allegations in Defendants’ cross claims and intends to vigorously defend against them while pursuing its
+Added: claims against the Defendants.
+Added: 7, 2023, Weird Science LLC (“Weird Science”), Wittekind, the William Anderson Wittekind 2020 Annuity Trust, the William Anderson
+Added: Wittekind 2021 Annuity Trust, the Dybul 2020 Angel Annuity Trust, and the Ty Mabry 2021 Annuity Trust (collectively, the “Trusts”)
+Added: (collectively, “Plaintiffs”) filed a Verified Complaint against the Company in the Court of Chancery of Delaware.
+Added: In the Verified
+Added: Complaint, Plaintiffs alleged that the Company breached the February 16, 2018 Investor Rights Agreement between the Company, Weird Science,
+Added: and RS Group ApS (the “Investor Rights Agreement”).
+Added: According to the Verified Complaint, the Investor Rights Agreement required
+Added: the Company to (i) notify all “Holders” of “Registrable Securities” at least 30 days prior to filing a registration
statement and (ii) afford such Holders an opportunity to have their Registrable Securities included in such registration statement.
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The Company moved to dismiss the Verified Complaint on September
−Removed: December 4, 2023, in lieu of opposing the motion to dismiss, Plaintiffs filed a Verified First Amended Complaint (“FAC”).
−Removed: In the FAC, Plaintiffs assert claims against the Company and others for purported breaches of the Investor Rights Agreement, fraud, tortious
−Removed: interference with a contract, and several other torts.
−Removed: Plaintiffs seek compensatory, exemplary, and punitive damages, as well as certain
−Removed: declaratory relief, specific performance, and pre- and post-judgment interest, costs, and attorneys’ fees.
−Removed: The Company filed a motion
−Removed: to dismiss the FAC on December 18, 2023 and the court held a hearing on November 15, 2024.
−Removed: At the hearing, the court dismissed (1) all
−Removed: claims brought on behalf of Wittekind and the Trusts, (2) the fraudulent concealment claim against the Company and others (without prejudice),
−Removed: and (3) the breach of contract claim against the Company related to a registration statement that was not filed in 2023.
−Removed: At the hearing,
−Removed: the court also found that punitive damages were not available to Plaintiffs.
+Added: 4, 2023, in lieu of opposing the motion to dismiss, Plaintiffs filed a Verified First Amended Complaint (“FAC”).
+Added: Plaintiffs assert claims against the Company and others for purported breaches of the Investor Rights Agreement, fraud, tortious interference
+Added: with a contract, and several other torts.
+Added: Plaintiffs seek compensatory, exemplary, and punitive damages, as well as certain declaratory
+Added: relief, specific performance, and pre- and post-judgment interest, costs, and attorneys’ fees.
+Added: The Company filed a motion to dismiss
+Added: the FAC on December 18, 2023 and the court held a hearing on November 15, 2024.
+Added: At the hearing, the court dismissed (1) all claims brought
+Added: on behalf of Wittekind and the Trusts, (2) the fraudulent concealment claim against the Company and others (without prejudice), and (3)
+Added: the breach of contract claim against the Company related to a registration statement that was not filed in 2023.
+Added: At the hearing, the court
+Added: also found that punitive damages were not available to Plaintiffs.
The court took the remaining issues briefed on the Company’s
motion to dismiss under advisement.
−Removed: On February 26, 2025, the court ruled on the balance of the claims against the Company and (1) denied
−Removed: the Company’s motion to dismiss Weird Science’s breach of contract claims related to registration statements filed in 2020
−Removed: (2) dismissed the fraudulent inducement claim as time barred;
+Added: 26, 2025, the Court ruled on the balance of the claims against the Company and (1) denied the Company’s motion to dismiss Weird
+Added: Science’s breach of contract claims related to registration statements filed in 2020 and 2022;
+Added: (2) dismissed the fraudulent inducement
+Added: claim as time barred;
and (3) dismissed the declaratory judgment claim.
−Removed: denies Plaintiffs’ allegations and remaining claims and intends to vigorously defend against these claims.
−Removed: On August 24, 2023, counsel on
−Removed: behalf of Weird Science, Wittekind, individually, and Wittekind, as trustee of the Trusts served a demand to inspect the Company’s
−Removed: books and records (the “Demand”) pursuant to Delaware General Corporation Law, § 220 (“Section 220”).
−Removed: Demand seeks the Company’s books and records in connection with various issues identified in the Demand.
−Removed: The Company takes its obligations
−Removed: under Section 220 seriously and, to the extent that the requests are proper under Section 220, intends to comply with those obligations.
+Added: The Company denies Plaintiffs’ allegations and remaining
+Added: claims and intends to vigorously defend against these claims.
+Added: 24, 2023, counsel on behalf of Weird Science, Wittekind, individually, and Wittekind, as trustee of the Trusts served a demand to inspect
+Added: the Company’s books and records (the “Demand”) pursuant to Delaware General Corporation Law, § 220 (“Section
+Added: The Demand seeks the Company’s books and records in connection with various issues identified in the Demand.
+Added: takes its obligations under Section 220 seriously and, to the extent that the requests are proper under Section 220, intends to comply
+Added: with those obligations.
On January 19, 2024, Weird Science
6 unchanged sentences
as its counsel to investigate the issues identified in the demand letters.
−Removed: The Special Committee’s investigation is ongoing.
On January 23, 2024, Weird Science
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remains pending.
−Removed: On June 21, 2024, the Company filed suit against Weird
−Removed: Science, Wittekind, and certain trusts in connection with the February 16, 2018 merger involving the Company and two companies closely
−Removed: associated with Gumrukcu.
−Removed: In the complaint, the Company alleges that Gumrukcu and others deliberately and fraudulently concealed a murder-for-hire
−Removed: scheme from the Company in order to induce the Company to enter into the merger agreement, which resulted in the defendants receiving
−Removed: shares and compensation.
−Removed: The Company asserts claims for fraudulent concealment, equitable fraud, unjust enrichment, and civil conspiracy
−Removed: and seeks, inter alia , equitable relief, including, but not limited to, return to the Company any shares received in connection
−Removed: with the merger, and damages.
−Removed: On October 1, 2024, the defendants moved to dismiss the complaint and a hearing has been scheduled for June
+Added: On June 21, 2024, the Company filed
+Added: suit against Weird Science, Gumrukcu, Wittekind, and certain trusts in connection with the February 16, 2018 merger involving the Company
+Added: and two companies closely associated with Gumrukcu.
+Added: In the complaint, the Company alleges that Gumrukcu and others deliberately and fraudulently
+Added: concealed a murder-for-hire scheme from the Company in order to induce the Company to enter into the merger agreement, which resulted
+Added: in the defendants receiving shares and compensation.
+Added: The Company asserts claims for fraudulent concealment, equitable fraud, unjust enrichment,
+Added: and civil conspiracy and seeks, inter alia , equitable relief, including, but not limited to, return to the Company any shares received
+Added: in connection with the merger, and damages.
+Added: On October 1, 2024, the defendants moved to dismiss the complaint.
+Added: A hearing took place on
+Added: June 25, 2025, and on November 7, 2025, the Court granted defendants’ motion and dismissed the complaint.
+Added: Lunai commenced an action against Predictive Oncology, Inc.
+Added: in the Delaware Court of Chancery claiming that POAI breached a “definitive” January 2025 Letter Agreement pursuant to which
+Added: Lunai was going to acquire POAI.
+Added: As a result of its breach, POAI made that acquisition impossible and dramatically devalued the share
+Added: price of stock Lunai had already acquired as well as the value of the company it was contractually entitled to acquire.
+Added: Lunai sought specific
+Added: performance or, in the alternative, money damages.
+Added: The parties have exchanged paper discovery and noticed depositions.
+Added: The action has
+Added: been held in abeyance while the parties attempt to negotiate a settlement.
Risk Factors.
2 unchanged sentences
Unregistered Sales of Equity Securities and Use of Proceeds.
+Added: On July 7, 2025, the Company issued 5.36 million shares
+Added: of common stock, valued at $16.1 million upon the conversion of convertible notes (see Note 6).
Defaults Upon Senior Securities.
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Compared sentence by sentence after normalising whitespace, quotation marks, case and digits, so re-formatting and restated figures do not read as changed language. Wording changes appear as one removal and one addition. The current filing and the prior one are authoritative.