1 unchanged sentence
Related Party Loans
−Removed: Over the period January 1, 2022 through June 30, 2022, certain of the Company’s directors and executive officers loaned the Company an aggregate of $2.1million to augment the Company’s working capital as reflected in the following table (in thousands):
+Added: Over the period January 1, 2022 through September 30, 2022, certain of the Company’s directors and executive officers loaned the Company an aggregate of $5.8 million to augment the Company’s working capital as reflected in the following table (in thousands):
Soomi Niihara(1)
8 unchanged sentences
Due on Demand
+Added: George Sekulich(2)
+Added: Due on Demand
Soomi Niihara(1)
2 unchanged sentences
Due on Demand
+Added: Alfred Lui(2)
+Added: Due on Demand
Hope International Hospice, Inc.(1)
2 unchanged sentences
Due on Demand
−Removed: Wei Pei Zen (2)
+Added: Wei Pei Derek Zen(2)
Due on Demand
3 unchanged sentences
Due on Demand
+Added: Yutaka and Soomi Niihara(1)
+Added: Hope International Hospice, Inc.(1)
+Added: Due on Demand
+Added: Yutaka and Soomi Niihara(1)
+Added: Yutaka and Soomi Niihara(1)
+Added: Hope International Hospice, Inc.(1)
+Added: Due on Demand
+Added: Yutaka and Soomi Niihara(1)
+Added: Due on Demand
Soomi Niihara is Dr.
1 unchanged sentence
Niihara, a Director and the Chairman, and Chief Executive Officer of the Company, is also a director and the Chief Executive Officer of Hope International Hospice, Inc., which is wholly owned by him and his wife.
−Removed: Officer or director.
−Removed: Osato, a director of Emmaus, and his wife are the sole owners of Osato Medical Clinic.
+Added: Officer or current or former director.
+Added: Osato, a former director of Emmaus, and his wife are the sole owners of Osato Medical Clinic.
+Added: Diverticulosis
+Added: As reported in the Annual Report, based upon data from the initial Pilot/Phase 1 study of the safety and efficacy of prescription grade L-glutamine oral powder (“PGLG”) in diverticulosis, in July 2021 we initiated a sub-study under an amendment to the original IND protocol.
+Added: The purpose of the sub-study was to standardize data collection and recording using video capture to support the accurate assessment of any changes in the sigmoid colon, the most frequent site for diverticulosis, as well as diverticulitis, a more severe manifestation of diverticulosis.
+Added: The sub-study objective was to provide additional safety and efficacy data to support further clinical development.
+Added: For the sub-study, five patients were administered oral L-glutamine 15g BID over six months beginning early this year.
+Added: Unfortunately, as the study was ending a patient in the sub-study experienced serious health complications unrelated to the sub-study which necessitated his withdrawal from the study before treatment could be completed, while other patients showed marginal improvement.
+Added: As a result, we do not have definitive data to conclude the study.
+Added: At present, we have plan for further study of PGLG in diverticulosis but are considering a future study in diverticulitis patients in order to possibly increase measurable clinical endpoints from the treatment with PGLG.
Incorporated by Reference
Exhibit Description
+Added: Warrant to Purchase Shares of Common Stock dated as of August 9, 2022
+Added: Promissory Note dated July 27, 2022
+Added: Promissory Note dated August 15, 2022
+Added: Promissory Note dated August 16, 2022
+Added: Promissory Note dated August 16, 2022
+Added: Promissory Note dated August 17, 2022
+Added: Promissory Note dated August 17, 2022
+Added: Promissory Note dated September 16, 2022
Certification of Chief Executive Officer pursuant to Item 601(b)(31) of Regulation S-K, as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002
14 unchanged sentences
Emmaus Life Sciences, Inc.
−Removed: August 15, 2022
+Added: November 14, 2022
/s/ Yutaka Niihara
5 unchanged sentences
Compared sentence by sentence after normalising whitespace, quotation marks, case and digits, so re-formatting and restated figures do not read as changed language. Wording changes appear as one removal and one addition. The current filing and the prior one are authoritative.