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Our research services utilize our research center to assist pharmaceutical and biotechnology companies with their drug development process.
−Removed: We perform studies which we believe may predict the efficacy of experimental oncology drugs or approved drugs as stand-alone therapies or in combination with other drugs and can stimulate the results of human clinical trials.
+Added: We perform studies which we believe may predict the efficacy of experimental oncology drugs or approved drugs as stand-alone therapies or in combination with other drugs and can simulate the results of human clinical trials.
These studies include in vivo studies that rely on implanting multiple tumors from our TumorBank in mice and testing the therapy of interest on these tumors.
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Lumin leverages Champions’ large Datacenter coupled with analytics and artificial intelligence to provide a robust tool for computational cancer research.
−Removed: It is the combination of the Datacenter and the analytics that create a unique foundation for Lumin.
+Added: It is the combination of the Datacenter and the analytics that create the foundation for Lumin.
Insights developed using Lumin can provide the basis for biomarker hypotheses, reveal potential mechanisms of therapeutic resistance, and guide the direction of additional preclinical evaluations.
+Added: See Note 4 to the consolidated financial statements for further discussion as to impairment of Lumin assets in fiscal 2023.
Drug Discovery and Development Business
−Removed: We began investing in drug discovery in fiscal year 2021.
Our nascent drug discovery and development business leverages the computational and experimental capabilities within our platforms.
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Our success in these efforts is demonstrated by the growing number of customers who have increased their annual spend on our services over the years.
−Removed: Our SaaS business development team is focused on identifying and selling subscriptions to new customers, ensuring a high level of use from these subscribers, and increasing our revenue from existing customers through the use of our cloud computing environment.
−Removed: Our sales approach is based on in informing our current research services customers and reaching out to new contacts within companies that we currently serve.
For the year ended April 30, 2023, revenues from our products and services totaled approximately $53.8 million, an increase of approximately 10% from the previous year.
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First, leverage a medical affairs team that works with a well established clinical network to facilitate access to patients diagnosed with prioritized tumors subtypes.
−Removed: Second, we utilize our legacy Personalized Oncology Services business to establish novel PDX models from patients who use this service.
+Added: Second, we maintain the ability to utilize our legacy Personalized Oncology Services business to establish novel PDX models from patients who use this service.
The PDX models are then deeply characterized at the phenotypic, molecular, and pharmacologic levels.
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We are also investing in the development of sophisticated analytical platforms which allow scientists to derive deeper insights when using our pharmacology platforms.
−Removed: experimental technologies are established they are made available to our research and development and target discovery teams.
−Removed: • Continued development of computational power:
+Added: Once these experimental technologies are established they are made available to our research and development and target discovery teams.
+Added: • Computational power:
We have developed sophisticated and innovative computational approaches.
−Removed: We continue to invest in the development of novel artificial intelligence, data structures, and analytics.
+Added: We have also invested in the development of novel artificial intelligence, data structures, and analytics.
Our goal is to leverage our unique Datacenter to establish elegant ways to better understand the molecular dynamics of cancer, and the development novel therapeutics.
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the global biopharmaceutical industry.
−Removed: The global oncology drug market is estimated to be $85B.
+Added: The global oncology drug market is estimated to be as high as $188B in 2023.
Competition in this industry is strong and based significantly on scientific and technological forces, which rely solely on the effectiveness of therapeutics designed to treat cancer.
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Compared sentence by sentence after normalising whitespace, quotation marks, case and digits, so re-formatting and restated figures do not read as changed language. Wording changes appear as one removal and one addition. The current filing and the prior one are authoritative.