19 unchanged sentences
Stockholders' Equity:
−Removed: Preferred stock, $ 0.001 par value, 5,000,000 shares authorized and 0 shares
−Removed: issued and outstanding
+Added: Preferred stock, $ 0.001 par value, 5,000,000 shares authorized and 0 shares issued and outstanding
Common stock, $ 0.001 par value, 75,000,000 shares authorized and 4,140,960 and
11 unchanged sentences
Three months ended
−Removed: March 31, 2023
−Removed: March 31, 2022
+Added: Six months ended
+Added: Six months ended
+Added: June 30, 2023
+Added: June 30, 2022
+Added: June 30, 2023
+Added: June 30, 2022
Operating expenses:
5 unchanged sentences
( 3,564,341 )
−Removed: Other expenses:
+Added: ( 8,951,897 )
+Added: ( 6,713,553 )
+Added: Other income (expenses):
+Added: Interest income
Interest expense
−Removed: Total other expenses
+Added: Total other income (expense)
$ ( 4,021,234 )
$ ( 3,565,952 )
+Added: $ ( 8,953,181 )
+Added: $ ( 6,717,730 )
Loss per share - basic
2 unchanged sentences
Weighted average shares outstanding - diluted
−Removed: See accompanying notes to the unaudited financial statements.
+Added: See accompanying notes to
+Added: the unaudited financial statements
Pharmaceuticals, Inc.
−Removed: of Stockholders' Equity
−Removed: For the three months ended March 31, 2023 and 2022
+Added: Statements of
+Added: Stockholders' Equity
+Added: For the six months ended June 30, 2023 and 2022
Stockholders'
7 unchanged sentences
( 55,647,624 )
+Added: Common stock issued for cash, net
+Added: Exercise of warrants
+Added: Stock-based compensation
+Added: ( 4,021,234 )
+Added: ( 4,021,234 )
+Added: Balance June 30, 2023
+Added: $ ( 59,668,858 )
Balance December 31, 2021
7 unchanged sentences
( 38,593,321 )
+Added: Stock-based compensation
+Added: ( 3,565,952 )
+Added: ( 3,565,952 )
+Added: Balance June 30, 2022
+Added: $ ( 42,159,273 )
See accompanying notes to the unaudited financial statements
1 unchanged sentence
Statements of Cash Flows
−Removed: Three Months Ended
−Removed: Three Months Ended
−Removed: March 31, 2023
−Removed: March 31, 2022
+Added: Six Months Ended
+Added: Six Months Ended
+Added: June 30, 2023
+Added: June 30, 2022
Cash Flows from Operating Activities:
3 unchanged sentences
Stock-based compensation
+Added: Loss of disposal of fixed assets
Changes in operating assets and liabilities:
5 unchanged sentences
( 6,439,733 )
+Added: Cash Flows from Investing Activities:
+Added: Purchase of property and equipment
+Added: Net cash used in investing activities
Cash Flows from Financing Activities:
2 unchanged sentences
Proceeds from sale of common stock
−Removed: Net cash provided by (used in) financing activities
+Added: Net cash provided by financing activities
Net change in cash and cash equivalents
5 unchanged sentences
Cash paid for income taxes
−Removed: See accompanying notes to the unaudited financial statements.
+Added: See accompanying notes to the unaudited financial
CNS Pharmaceuticals, Inc.
14 unchanged sentences
financial statements not misleading.
−Removed: Operating results for the three months ended March 31, 2023 are not necessarily indicative of the
−Removed: final results that may be expected for the year ending December 31, 2023.
−Removed: For more complete financial information, these unaudited financial
−Removed: statements should be read in conjunction with the audited financial statements for the period ended December 31, 2022 included in our
−Removed: Form 10-K filed with the SEC on March 31, 2023 (“Form 10-K”).
+Added: Operating results for the three and six months ended June 30, 2023 are not necessarily indicative
+Added: of the final results that may be expected for the year ending December 31, 2023.
+Added: For more complete financial information, these unaudited
+Added: financial statements should be read in conjunction with the audited financial statements for the period ended December 31, 2022 included
+Added: in our Form 10-K filed with the SEC on March 31, 2023 (“Form 10-K”).
Notes to the financial statements which would substantially
22 unchanged sentences
The amount in excess of
−Removed: the FDIC insurance as of March 31, 2023 was $ 4,860,531 .
+Added: the FDIC insurance as of June 30, 2023 was $ 4,029,251 .
The Company has not experienced losses on these accounts and management believes,
14 unchanged sentences
excludes common stock equivalents, because their inclusion would be anti-dilutive.
−Removed: As of March 31, 2023, the Company’s potentially
+Added: As of June 30, 2023, the Company’s potentially
dilutive shares and options, which were not included in the calculation of net loss per share, included warrants to purchase 2,268,827
common shares, and options for 128,588 common shares.
−Removed: As of March 31, 2022, the Company’s potentially dilutive shares and options,
+Added: As of June 30, 2022, the Company’s potentially dilutive shares and options,
which were not included in the calculation of net loss per share, included warrants to purchase 564,205 common shares, and options for
95,501 common shares.
−Removed: Recent Accounting Pronouncements - In June 2016, the FASB issued
−Removed: Accounting Standards Update No.
−Removed: 2016-13, Financial Instruments-Credit Losses:
+Added: Accounting Pronouncements - In June 2016, the FASB issued Accounting Standards Update No.
+Added: 2016-13, Financial
+Added: Instruments-Credit Losses:
Measurement of Credit Losses on Financial Instruments.
−Removed: 2016-13 requires measurement and recognition of expected credit losses for financial assets.
−Removed: In April 2019, the FASB issued clarification
−Removed: to ASU 2016-13 within ASU 2019-04, Codification Improvements to Topic 326, Financial Instruments-Credit Losses, Topic 815, Derivatives
−Removed: and Hedging, and Topic 825, Financial Instruments, or ASU 2016-13.
+Added: ASU 2016-13 requires measurement and recognition
+Added: of expected credit losses for financial assets.
+Added: In April 2019, the FASB issued clarification to ASU 2016-13 within ASU 2019-04,
+Added: Codification Improvements to Topic 326, Financial Instruments-Credit Losses, Topic 815, Derivatives and Hedging, and Topic 825,
+Added: Financial Instruments, or ASU 2016-13.
The guidance is effective for fiscal years beginning after December 15, 2022.
−Removed: The Company adopted this standard on January 1, 2023, which had no material impact on the Company’s financial statements.
+Added: adopted this standard on January 1, 2023, which had no material impact on the Company’s financial statements.
Note 3 – Note Payable
3 unchanged sentences
related to the note will be repaid over an 11-month period with the final payment due on October 31, 2023 .
−Removed: As of March 31, 2023 and December
+Added: As of June 30, 2023 and December
31, 2022, the Company’s note payable balance was $ 166,396 and $ 409,968 , respectively.
4 unchanged sentences
The specific rights of the preferred stock shall be determined by the board of directors.
+Added: Pursuant to the terms of the Capital on
+Added: Demand™ Sales Agreement with JonesTrading Institutional Services LLC and Brookline Capital Markets, a division of Arcadia
+Added: Securities, LLC (collectively, the “Agent”), the Company may sell from time to time, through the Agent, shares of the
+Added: Company’s common stock with an aggregate sales price of up to $20.0 million.
+Added: During the quarter ended June 30, 2023, the
+Added: Company sold 659,677
+Added: shares of common stock to the Agent for net proceeds of $ 1,969,107 .
Stock Options
3 unchanged sentences
awards for up to 66,667 shares of common stock.
−Removed: No key employee may receive more than 16,667 shares of common stock (or options to purchase
−Removed: more than 16,667 shares of common stock) in a single year.
In 2020, the Board of Directors of the Company approved the CNS Pharmaceuticals,
2 unchanged sentences
awards for up to 100,000 shares of common stock.
−Removed: No key employee may receive more than 25,000 shares of common stock (or options to purchase
−Removed: more than 25,000 shares of common stock) in a single year.
On December 30, 2022, the Board of Directors of the Company appointed
11 unchanged sentences
total fair value of these option grants at issuance was $ 25,820 .
−Removed: During the three months ended March 31, 2023 and 2022, the Company
−Removed: recognized $ 272,446 and $ 336,685 of stock-based compensation, respectively, related to outstanding stock options.
−Removed: At March 31, 2023, the
−Removed: Company had $ 1,169,948 of unrecognized expenses related to outstanding options.
+Added: On May 3, 2023, the Board of Directors of the Company appointed
+Added: Cockroft, M.D., M.B.A as an independent member of the Company’s Board of Directors.
+Added: Cockroft was granted a
+Added: ten-year option to purchase 2,099
+Added: shares of Company common stock at an exercise price of $ 1.67
+Added: vesting in 36 equal monthly installments succeeding the issuance date.
+Added: The total fair value of these option grants at issuance was
+Added: During the six months ended June 30, 2023 and 2022, the Company recognized
+Added: $ 544,248 and $ 605,657 of stock-based compensation, respectively, related to outstanding stock options.
+Added: At June 30, 2023, the Company had
+Added: $ 803,468 of unrecognized expenses related to outstanding options.
The following table summarizes the stock option
−Removed: activity for the three months ended March 31, 2023:
+Added: activity for the six months ended June 30, 2023:
Schedule of Stock Option Activity
1 unchanged sentence
Outstanding, December 31, 2022
−Removed: Outstanding, March 31, 2023
−Removed: Exercisable, March 31, 2023
−Removed: As of March 31, 2023, the outstanding stock options have a weighted
−Removed: average remaining term of 7.41 years and no aggregate intrinsic value of options vested and outstanding.
−Removed: As of March 31, 2023, there were
−Removed: no awards remaining to be issued under the 2017 Plan and 2,092 awards remaining to be issued under the 2020 Plan.
+Added: Outstanding, June 30, 2023
+Added: Exercisable, June 30, 2023
+Added: As of June 30, 2023, the outstanding stock options have a weighted
+Added: average remaining term of 7.20
+Added: years and aggregate intrinsic value of options vested and outstanding of $ 8,133 and $ 46,248 , respectively.
+Added: As of June 30, 2023,
+Added: there were no awards remaining to be issued under the 2017 Plan or the 2020 Plan.
Stock Warrants
−Removed: During the three months ended March 31, 2023, the Company received
−Removed: $ 609 in cash proceeds from the exercise of 609,000 warrants previously issued at an exercise price of $ 0.001 .
+Added: During the six months ended June 30, 2023, the Company received
+Added: $ 725,668 in cash proceeds
+Added: from the exercise of 238,958 warrants previously issued at an exercise price of $3.03 and 1,625,000 warrants previously issued at an exercise price of $0.001.
The following table summarizes the stock warrant
−Removed: activity for the three months ended March 31, 2023:
+Added: activity for the six months ended June 30, 2023:
Schedule of warrants activity
1 unchanged sentence
Outstanding, December 31, 2022
−Removed: Outstanding, March 31, 2023
−Removed: Exercisable, March 31, 2023
−Removed: As of March 31, 2023, the outstanding and exercisable warrants have
−Removed: a weighted average remaining term of 4.58 years and have aggregate intrinsic value of $ 1,014,984 .
+Added: ( 1,863,958 )
+Added: Outstanding, June 30, 2023
+Added: Exercisable, June 30, 2023
+Added: As of June 30, 2023, the outstanding and exercisable warrants have
+Added: a weighted average remaining term of 2.75 years and had no aggregate intrinsic value.
Restricted Stock Units
−Removed: During the three months ended March 31, 2023, the Company recognized
−Removed: $ 5,962 of stock-based compensation, related to outstanding stock RSUs.
−Removed: At March 31, 2023, the Company had $ 71,550 of unrecognized expenses
−Removed: related to outstanding RSUs.
+Added: During the six months ended June 30, 2023, the Company recognized $ 11,925
+Added: of stock-based compensation, related to outstanding RSUs.
+Added: At June 30, 2023, the Company had $ 65,587 of unrecognized expenses related
+Added: to outstanding RSUs.
The following table summarizes the RSUs activity
−Removed: for the three months ended March 31, 2023:
+Added: for the six months ended June 30, 2023:
Schedule of restricted stock units activity
1 unchanged sentence
Non-vested, December 31, 2022
−Removed: Non-vested, March 31, 2023
+Added: Non-vested, June 30, 2023
Performance Units
−Removed: During the three months ended March 31, 2023, the Company recognized
+Added: During the six months ended June 30, 2023, the Company recognized $ 23,810
related to outstanding stock PUs.
−Removed: At March 31, 2023, the Company had $ 122,043 of unrecognized expenses related to PUs.
+Added: At June 30, 2023, the Company had $ 110,138 of unrecognized expenses related to PUs.
The following table summarizes the PUs activity
−Removed: for the three months ended March 31, 2023:
+Added: for the six months ended June 30, 2023:
Schedule of performance units activity
1 unchanged sentence
Non-vested, December 31, 2022
−Removed: Non-vested, March 31, 2023
+Added: Non-vested, June 30, 2023
Note 5 – Commitments and Contingencies
26 unchanged sentences
Climaco’s 2021 annual base salary
−Removed: On June 28, 2019, our we entered into employment letters with Drs.
+Added: On June 28, 2019, we entered into employment letters with Drs.
Silberman and Picker.
9 unchanged sentences
member shall receive annual cash compensation of $68,600.
−Removed: During the three months ended March 31, 2023 and 2022, the Company paid
+Added: During the six months ended June 30, 2023 and 2022, the Company paid $ 0 and
$ 65,834 related to the Scientific Advisory Board compensation.
−Removed: As of March 31, 2023, the Company has accrued $ 117,284
−Removed: related to Mr.
−Removed: Hsu’s Scientific Advisory Board compensation.
+Added: As of June 30, 2023, the Company has accrued $ 134,434 related to Dr.
+Added: Scientific Advisory Board compensation.
WP744 Portfolio (Berubicin)
26 unchanged sentences
thereby fulfilling all conditions precedent and completing the acquisition of the intellectual property discussed in the HPI
−Removed: During the three months ended March 31, 2023 and 2022, the Company recognized $ 12,500 and $ 87,500 ,respectively, related to this agreement.
−Removed: Unrelated to this agreement, from time to time, the Company purchases
−Removed: pharmaceutical products from HPI which are necessary for the manufacturing of Berubicin API and drug product in related party
−Removed: transactions which are reviewed and approved by the Company’s audit committee based upon the standards of providing superior
−Removed: pricing and time to delivery than that available from unrelated third parties.
−Removed: During the three months ended March 31, 2023 and
−Removed: 2022, the Company expensed $ 0
+Added: During the six months ended June 30, 2023 and 2022, the Company recognized $ 25,000
+Added: and $ 175,000 ,
+Added: respectively, related to this agreement.
+Added: Unrelated to this agreement, from time to time, the Company purchases pharmaceutical
+Added: products from HPI which are necessary for the manufacturing of Berubicin API and drug product in related party transactions which
+Added: are reviewed and approved by the Company’s audit committee based upon the standards of providing superior pricing and time to
+Added: delivery than that available from unrelated third parties.
+Added: During the six months ended June 30, 2023 and 2022, the Company expensed
respectively related to the purchase of pharmaceutical products from HPI.
21 unchanged sentences
Priebe, our founder.
−Removed: On November 21, 2022, CNS entered into an Investigational Medicinal
−Removed: Product Supply Agreement with Pomeranian Medical University (“PUM”) in Szczecin, Poland.
+Added: On November 21, 2022, CNS entered into an Investigational Medicinal Product
+Added: Supply Agreement with Pomeranian Medical University (“PUM”) in Szczecin, Poland.
CNS agreed to sell berubicin hydrochloride
6 unchanged sentences
As of December 31, 2022,
−Removed: the reference standards had been delivered and were recognized in Accounts Receivable and as a reduction to research and development expense.
−Removed: As of March 31, 2023, the first batch of berubicin drug product vials have been ordered and delivered in April 2023.
+Added: the reference standards were delivered, and the Company recognized $ 1,302 in accounts receivable and as a reduction to research and development
+Added: In April 2023, the first batch of berubicin drug product vials were delivered, and the Company recognized $ 196,303
+Added: in accounts receivable and as a reduction to research and development expense.
+Added: As of June 30, 2023, the outstanding accounts receivable
+Added: balance was $ 197,605 , which was collected in full on July 6, 2023.
On August 31, 2018, the Company entered into a sublicense agreement
27 unchanged sentences
WP1244 Portfolio
−Removed: On January 10, 2020, Company entered into a Patent and Technology License
−Removed: Agreement (“Agreement”) with The Board of Regents of The University of Texas System, an agency of the State of Texas, on behalf
−Removed: of The University of Texas M.
+Added: On January 10, 2020, Company entered into a Patent and Technology
+Added: License Agreement (“Agreement”) with The Board of Regents of The University of Texas System, an agency of the State of
+Added: Texas, on behalf of The University of Texas M.
Anderson Cancer Center (“UTMDACC”).
−Removed: Pursuant to the Agreement, the Company obtained a royalty-bearing,
−Removed: worldwide, exclusive license to certain intellectual property rights, including patent rights, related to the Company’s recently
−Removed: announced WP1244 drug technology.
−Removed: In consideration, the Company must make payments to UTMDACC including an up-front license fee, annual
−Removed: maintenance fee, milestone payments and royalty payments (including minimum annual royalties) on sales of licensed products developed
−Removed: under the Agreement.
+Added: Pursuant to the Agreement, the
+Added: Company obtained a royalty-bearing, worldwide, exclusive license to certain intellectual property rights, including patent rights,
+Added: related to the Company’s recently announced WP1244 drug technology.
+Added: In consideration, the Company must make payments to
+Added: UTMDACC including an up-front license fee, annual maintenance fee, milestone payments and royalty payments (including minimum annual
+Added: royalties) on sales of licensed products developed under the Agreement.
The term of the Agreement expires on the last to occur of:
−Removed: (a) the expiration of all patents subject to the Agreement,
−Removed: or (b) fifteen years after execution;
−Removed: provided that UTMDACC has the right to terminate this Agreement in the event that the Company fails
−Removed: to meet certain commercial diligence milestones.
−Removed: The commercial diligence milestones are as follows (i) initiated PC toxicology to support
−Removed: filing of Investigational New Drug Application (“IND”) or New Drug Application (“NDA”) for the Licensed Product
−Removed: within the eighteen (18) month period following the Effective Date (ii) file and IND for the Licensed Product within three (3) year period
−Removed: following the Effective Date and (iii) Commencement of Phase I Study within the five (5) year period following the Effective Date.
−Removed: the three months ended March 31, 2023 and 2022, the Company paid $ 11,744 and $ 44,424 , respectively.
+Added: (a) the expiration of all patents subject to the Agreement, or (b) fifteen years after execution;
+Added: provided that UTMDACC has the
+Added: right to terminate this Agreement in the event that the Company fails to meet certain commercial diligence milestones.
+Added: commercial diligence milestones are as follows (i) initiated PC toxicology to support filing of Investigational New Drug Application
+Added: (“IND”) or New Drug Application (“NDA”) for the Licensed Product within the eighteen (18) month period
+Added: following the Effective Date (ii) file and IND for the Licensed Product within three (3) year period following the Effective Date
+Added: and (iii) Commencement of Phase I Study within the five (5) year period following the Effective Date.
+Added: The Company has not met the
+Added: commercial diligence milestones required as of the date hereof.
+Added: As such, UTMDACC has the right to terminate the Agreement upon
+Added: notice to the Company.
+Added: As of the date of this report, UTMDACC has not notified of the Company of its intention to terminate the
+Added: During the six months ended June 30, 2023 and 2022, the Company paid $ 27,341
+Added: and $ 44,424 ,
+Added: respectively.
On May 7, 2020, pursuant to the WP1244 Portfolio license agreement
20 unchanged sentences
Turkey, Belgium, Switzerland, Sweden, Portugal, Norway, Denmark, Ireland, Finland, Luxembourg, Iceland.
−Removed: Pursuant to the Agreement, the Company agreed to pay WPD the following
−Removed: (i) an upfront payment of $ 225,000 to WPD (paid in April 2020);
−Removed: and (ii) within thirty days of the verified achievement of the
−Removed: Phase II Milestone, (such verification shall be conducted by an independent third party mutually acceptable to the parties hereto), the
−Removed: Company will make a payment of $ 775,000 to WPD.
−Removed: WPD agreed to pay the Company a development fee of 50% of the net sales for any products
−Removed: in the above territories;
−Removed: provided that Poland shall not be included as a territory after WPD receives marketing approval for a product
−Removed: in one-half of the countries included in the agreed upon territories or upon the payment by WPD to the Company of development fees of
−Removed: $ 1.0 million .
−Removed: The term of the Agreement will expire on the expiration of the sublicense pursuant to which WPD has originally sublicensed
−Removed: the products.
−Removed: Note 6 – Subsequent Events
−Removed: Subsequent to March 31, 2023, a total of 1,016,000 Pre-Funded
−Removed: Warrants (exercisable into one share of common stock at a price per share of $0.001) were exercised by investors in the financing completed
−Removed: on November 30, 2022.
−Removed: In addition, a total of 238,958 Investor Warrants (exercisable into one share of common stock at a price
−Removed: per share of $3.03) were exercised by investors for net proceeds of $724,043 .
+Added: Pursuant to the Agreement, the Company agreed to pay WPD the
+Added: following payments:
+Added: (i) an upfront payment of $ 225,000
+Added: to WPD (paid in April 2020);
+Added: and (ii) within thirty days of the verified achievement of the Phase II Milestone, (such verification
+Added: shall be conducted by an independent third party mutually acceptable to the parties hereto), the Company was required to make a
+Added: payment of $ 775,000
+Added: WPD agreed to pay the Company a development fee of 50% of the net sales for any products in the above territories;
+Added: that Poland shall not be included as a territory after WPD receives marketing approval for a product in one-half of the countries
+Added: included in the agreed upon territories or upon the payment by WPD to the Company of development fees of $ 1.0
+Added: The term of the Agreement stated it would expire on the expiration
+Added: of the sublicense pursuant to which WPD has originally sublicensed the products.
+Added: In March 2023, the sublicense pursuant to which WPD originally
+Added: sublicensed the products was terminated.
+Added: As such, the Agreement has been terminated.
+Added: 6 – Subsequent Events
Pursuant to the terms of the Capital on Demand™
2 unchanged sentences
aggregate sales price of up to $20.0 million.
−Removed: On April 20, 2023, the Company sold 659,677 shares of common stock to the Agent
−Removed: for net proceeds of $1,969,107.
−Removed: On May 3, 2023, Bettina Cockroft, M.D., M.B.A joined our Board of Directors
−Removed: as an independent director.
−Removed: Cockroft has not been appointed to any Board committees at this time.
−Removed: Cockroft will participate in
−Removed: the Company’s standard compensation program for non-employee directors, which was filed as Exhibit 10.1 to the Company’s Form
−Removed: 10-Q for the quarter ended June 30, 2022.
−Removed: In addition, Dr.
−Removed: Cockroft was granted a ten-year option to purchase 8,300 shares of Company
−Removed: common stock at an exercise price of $1.67 vesting in 36 equal monthly installments succeeding the grant date subject to continued service
−Removed: on the Company's Board of Directors on each vesting date.
+Added: Subsequent to the quarter ended on June 30, 2023, the Company sold 58,591 shares
+Added: of common stock to the Agent for net proceeds of $124,279.
+Added: On August 4, 2023, the Board of Directors approved the issuance of
+Added: 6,500 options to Dr.
+Added: The options have a ten-year term at an exercise price of $2.27 and vest in 36 equal monthly installments
+Added: succeeding the issuance date.
+Added: This grant is contingent upon shareholder approval of an amendment to our equity compensation
+Added: plan to increase the number of shares authorized under the plan to allow for the registration of the shares underlying the options
Compared sentence by sentence after normalising whitespace, quotation marks, case and digits, so re-formatting and restated figures do not read as changed language. Wording changes appear as one removal and one addition. The current filing and the prior one are authoritative.