−Removed: We are a development stage advanced materials company dedicated to the development of technology and processes that, if successful, will allow for the enrichment of natural isotopes into higher concentration products, which could be used in several industries.
−Removed: Our proprietary technologies, the Aerodynamic Separation Process (“ASP technology”) and Quantum Enrichment
−Removed: technology (“QE technology”), are designed to enable the production of isotopes used in several industries.
−Removed: Our initial focus is on the production and commercialization of enriched Carbon-14 (“C-14”), Silicon-28 (“Si-28”) and Ytterbium-176 (“Yb-176”).
−Removed: We have completed the commissioning phase and are commencing commercial production at our C-14 and Si-28 enrichment facilities in Pretoria, South Africa.
−Removed: We are in the process of commissioning and commencing commercial production at our Yb-176 enrichment facility in Pretoria, South Africa.
−Removed: Our C-14 and Si-28 enrichment facilities utilize the ASP technology and our Yb-176 enrichment facility utilizes QE technology.
−Removed: We expect our first three enrichment facilities to generate commercial product during 2025.
+Added: We are an advanced materials company dedicated to the development of a differentiated isotope enrichment platform to strengthen global supply chain access to critical materials used in nuclear medicine, next-generation semiconductors, and nuclear energy.
+Added: In addition, in January 2026, we acquired Renergen, which is South Africa’s leading onshore natural gas explorer and the first integrated producer of both liquid helium and LNG (as discussed further below).
+Added: Our proprietary enrichment technologies, the Aerodynamic Separation Process (“ASP technology”) and Quantum Enrichment technology (“QE technology”), are designed to enable the production of isotopes for a range of industrial and advanced technology applications.
+Added: Our initial focus with respect to our isotope enrichment platform is on the production and commercialization of enriched Carbon-14 (“C-14”), Silicon-28 (“Si-28”) and Ytterbium-176 (“Yb-176”).
+Added: We commenced commercial production of enriched isotopes at both of our ASP enrichment facilities located in Pretoria, South Africa during the first half of 2025.
+Added: Our first ASP enrichment facility is designed to enrich light isotopes, such as C-14 and C-12.
+Added: The second ASP enrichment facility, which is substantially larger than the first, should have the potential to enrich kilogram quantities of relatively heavier isotopes, including but not limited to Si-28.
+Added: We are targeting initial commercial shipments of enriched C-14 in mid-2026.
+Added: We are targeting initial commercial shipments of enriched Si-28 during the second quarter of 2026.
+Added: We have also completed the commissioning phase and are producing commercial samples of highly enriched Yb-176 at our third enrichment facility, a QE technology facility, which is our first laser-based enrichment plant.
+Added: We are targeting initial commercial shipments of Yb-176 in mid-2026 or the third quarter of 2026.
In addition, we have started planning additional isotope enrichment plants both in South Africa and in other jurisdictions, including Iceland and the United States.
2 unchanged sentences
We believe the Yb-176 we may produce using the QE technology may be used to create radiotherapeutics that treat various forms of oncology.
−Removed: In addition, we are considering the future development of the ASP technology for the separation of Zinc-68 and Xenon-129/136 for potential use in the healthcare end market, Germanium 70/72/74 for potential use in the semiconductor end market, and Chlorine -37 for potential use in the nuclear energy end market.
+Added: We are considering the future development of the ASP technology for the separation of Zinc-68 and Xenon-129/136 for potential use in the healthcare end market, Germanium 70/72/74 for potential use in the semiconductor end market, and Chlorine -37 for potential use in the nuclear energy end market.
We are also considering the future development of QE technology for the separation of Nickel-64, Gadolinium-160, Ytterbium-171, Lithium-6 and Lithium-7.
−Removed: We are currently pursuing an initiative to apply our enrichment technologies to the enrichment of Uranium-235 (“U-235”) in South Africa.
−Removed: We believe that the U-235 we may produce using quantum enrichment technology may be commercialized as a nuclear fuel component for use in the new generation of high-assay low-enriched uranium (HALEU)-fueled small modular reactors that are now under development for commercial and government uses.
−Removed: In furtherance of our uranium enrichment initiative, in October 2024, we entered into a term sheet with TerraPower, LLC which contemplates the parties entering into definitive agreements pursuant to which TerraPower would provide funding for the construction of a HALEU production facility and agree to purchase all HALEU produced at the facility over a 10-year period after the planned completion of the facility in 2027.
−Removed: In addition, in November 2024, we entered into a memorandum of understanding with The South African Nuclear Energy Corporation (Necsa), a South African state-owned company responsible for undertaking and promoting research and development in the field of nuclear energy and radiation sciences, to collaborate on the research, development and ultimately the commercial production of advanced nuclear fuels.
−Removed: Subject to the receipt of funding and all required permits and licenses to begin enrichment of U-235 in South Africa, it is anticipated that the research, development and ultimate construction of a HALEU production facility will take place at South Africa’s main nuclear research center at Pelindaba in Pretoria.
−Removed: We operate principally through subsidiaries.
−Removed: ASP Isotopes Guernsey Limited (the holding company of ASP Isotopes South Africa (Proprietary) Limited, Enlightened Isotopes (Pty) Ltd) and ASPI South Africa Asset Finance (Pty) Ltd, which will be focused on the development and commercialization of high-value, low-volume isotopes for highly specialized end markets (such as C-14, Si-28 and Yb-176).
−Removed: In September 2023, we formed a new subsidiary, Quantum Leap Energy LLC, which also has a subsidiary in the United Kingdom (Quantum Leap Energy Ltd), to focus on the development and commercialization of advanced nuclear fuels such as HALEU and Lithium-6.
−Removed: ASP Isotopes UK Ltd is the owner of our technology.
−Removed: In addition, we have a 51% ownership stake in PET Labs Pharmaceuticals Proprietary Limited (PET Labs), a South African radiopharmaceutical operations company focused on the production of fluorinated radioisotopes and active pharmaceutical ingredients, through which we entered the downstream medical isotope production and distribution market.
−Removed: Our corporate structure and ownership of our subsidiaries is set forth in the chart below:
−Removed: As of December 31, 2023, we managed our operations as a single segment, specialist isotopes and related services.
−Removed: Beginning in 2024, primarily as a result of the increased business activities of our subsidiary, Quantum Leap Energy LLC, we manage our operations as two operating segments:
+Added: QLE is currently pursuing an initiative to apply our enrichment technologies to the enrichment of Uranium-235 (“U-235”) in South Africa.
+Added: We believe that the U-235 QLE may produce has the potential to be commercialized as a nuclear fuel component for use in the new generation of high-assay low-enriched uranium (“HALEU”)-fueled small modular reactors that are now under development for commercial and government uses.
+Added: In furtherance of our uranium enrichment initiative in South Africa, we have entered into certain definitive agreements with TerraPower, LLC (“TerraPower”), including a term loan subject to conditions to support construction of a new uranium enrichment facility at Pelindaba, South Africa and supply agreements for the future supply of HALEU to TerraPower, as a customer.
+Added: In addition, QLE’s South African subsidiary has entered into a Pre-Implementation Services Contract Agreement (“Services Contract”) with The South African Nuclear Energy Corporation (“Necsa”), a South African state-owned company responsible for undertaking and promoting research and development in the field of nuclear energy and radiation sciences, pursuant to which Necsa has agreed to provide to QLE’s South African subsidiary certain facilities, infrastructure, utilities and services related to the siting, design, construction, commission and operation of an enrichment facility on the Necsa site in Pelindaba.
+Added: In the period since our inception to date, we have not applied our enrichment technologies to the
+Added: enrichment of U-235, nor received permission or regulatory approval to conduct testing of our enrichment technologies on U-235, except for the activities contemplated by the Services Contract with Necsa.
+Added: Our expectation that QLE’s initiative to apply our enrichment technologies to the enrichment of U-235 could be successful is based upon research conducted by certain of our scientists prior to joining the company, as well as the demonstrated effectiveness of QE technology on Yb-176.
+Added: QLE acquired a controlling interest in Skyline in August 2025.
+Added: Skyline is a holding company, and its operations are conducted through its wholly owned operating subsidiaries, Kin Chiu Engineering Limited and Kin Chiu Development Company Limited.
+Added: Operations primarily consist of construction activities which include public civil engineering works, such as road and drainage works, in Hong Kong.
+Added: Skyline mostly undertakes civil engineering works in the role as a subcontractor but is fully qualified to undertake such works in the capacity of a main contractor.
+Added: QLE intends to pursue opportunities to acquire assets in the critical materials supply chain.
+Added: We acquired Renergen in January 2026.
+Added: Renergen is South Africa’s leading onshore natural gas explorer and the first integrated producer of both liquid helium and LNG, both of which are produced from the natural gas reserve base that underpins Renergen’s natural gas development project (the “Virginia Gas Project”).
+Added: The Virginia Gas Project includes (i) the liquefaction of natural gas into LNG, (ii) the separation of helium from natural gas, and (iii) the further liquefaction of helium into 99.999% pure liquid helium.
+Added: This liquefaction and separation takes place at Renergen’s natural gas processing plant in the Free State Province of South Africa (the “Viriginia Gas Plant”).
+Added: Renergen’s principal asset is its 94.5% equity ownership in Tetra4, which holds an onshore petroleum production right and is the entity developing the Virginia Gas Project.
+Added: Our Subsidiaries
+Added: We operate principally through our subsidiaries as described below.
+Added: Specialist Isotopes .
+Added: ASP Isotopes Guernsey Limited (the holding company for certain subsidiaries in the Cayman Islands, South Africa, Iceland and the United Kingdom) is focused on the development and commercialization of high-value, low-volume isotopes for highly specialized end markets (such as C-14, Molybdenum-100 (“Mo-100"), and Si-28).
+Added: ASP Isotopes UK Ltd is the owner of our enrichment technology.
+Added: Quantum Leap Energy .
+Added: In September 2023, we formed QLE, which also has subsidiaries in the United Kingdom (Quantum Leap Energy Limited) and South Africa (Quantum Leap Energy (Pty) Limited), to focus on the development and commercialization of advanced nuclear fuels, such as HALEU and Lithium-6.
+Added: QLE’s direct wholly owned subsidiary Quantum Leap Energy Limited (“QLE UK”), has its operations in the United Kingdom.
+Added: QLE UK’s direct wholly owned subsidiary, Quantum Leap Energy Proprietary Limited (“QLE South Africa”), has its operations in South Africa.
+Added: QLE also formed QLE TP Funding SPE LLC, a Delaware limited liability company (the “QLE SPE Borrower”), as a wholly owned subsidiary to act as a special purpose borrower for a loan transaction with TerraPower, a US nuclear innovation company.
+Added: The QLE SPE Borrower has formed a subsidiary in South Africa to act as the project company for a proposed new uranium enrichment facility at Pelindaba, South Africa.
+Added: QLE’s mission is to address perceived gaps in the nuclear fuel cycle, promote safe nuclear power, and enhance the sustainability of the nuclear fuel cycle for advanced nuclear reactors and fusion systems, as well as the existing nuclear fleet.
+Added: We believe that many advanced nuclear reactors, including small modular reactors (“SMRs”), will rely on fuels with higher uranium enrichment levels, specifically HALEU, which we intend to produce.
+Added: QLE also intends to produce high-isotopic purity fuel feedstock, such as Lithium-6, for fusion reactors, and by extension, Lithium-7 for Light Water Reactor control.
+Added: These fuels may enable greater efficiency, compact reactor footprints, and lengthened operational cycles between refueling.
+Added: Given the flexible nature of our enrichment technology and integrated value chain approach, QLE also intends to make available LEU+ to the existing fleet of nuclear reactors currently running on LEU, thus enabling existing reactors to lengthen the time between refueling, cut costs and boost power output.
+Added: As previously announced, our board of directors intends to pursue the separation of our Nuclear Fuels business and Specialist Isotopes and Related Services business into two independent companies.
+Added: The regulatory landscape and supply chain for nuclear fuel production differs significantly from that of medical isotopes, hence we and QLE have different business models and we believe that both companies would benefit if QLE is independently managed and financed.
+Added: We plan to effect the separation through a listing of QLE in a transaction that results in QLE existing as a separate public company with shares listed on a U.S.
+Added: national securities exchange and a portion of QLE’s common equity being distributed to our stockholders as of a to-be-determined future record date.
+Added: Although no assurance can be given, our goal is to list QLE on such exchange, subject to market conditions, obtaining applicable approvals and consents, and complying with applicable rules and regulations and public market trading and listing requirements.
+Added: In November 2025, we announced that QLE had confidentially submitted a draft registration statement on Form S-1 to the SEC relating to the proposed initial public offering of QLE’s Class A common stock.
+Added: While we currently expect that a listing of QLE as a separate public company is the most likely separation transaction, our board of directors remains committed to maximizing shareholder value creation, and will continue to evaluate other options for separation to maximize shareholder value.
+Added: We entered into a number of agreements with QLE, including a License Agreement, pursuant to which QLE has licensed from us the rights to technologies and methods used to separate U-235 and Lithium-6 (including but not limited to the QE and ASP technologies) in exchange for a perpetual royalty in the amount of 10% of all future QLE revenues, and an Engineering, Procurement
+Added: and Construction (“EPC”) Services Framework Agreement, pursuant to which we will provide services for the engineering, procurement and construction of one or more turnkey U-235 and Lithium-6 enrichment facilities in locations to be identified by QLE and owned or leased by QLE, and commissioning, start-up and test services for each such facility, subject to the receipt of all applicable regulatory approvals, permits, licenses, authorizations, registrations, certificates, consents, orders, variances and similar rights.
+Added: We have a 51% ownership stake in PET Labs, a South African radiopharmaceutical operations company focused on the production of fluorinated radioisotopes and active pharmaceutical ingredients, through which we entered the downstream medical isotope production and distribution market.
+Added: Under the terms of the Share Purchase Agreement pursuant to which we acquired the shares in PET Labs, we agreed to pay a total of $2.0 million for the shares in two installments, which has been paid in full as of December 2025.
+Added: In addition, we have an option to purchase the remaining 49% of the outstanding equity in PET Labs, exercisable until January 31, 2027, for $2.2 million.
+Added: East Coast Nuclear Pharmacy.
+Added: In October 2025, we completed the acquisition of East Coast Nuclear Pharmacy ("ECNP").
+Added: The acquisition is intended to supplement the distribution of our pipeline.
+Added: Pursuant to the terms of the agreement, we acquired 100% of the issued and outstanding membership interests for total purchase consideration of $2.5 million of which $2.0 million was paid up front in cash and the remaining $0.5 million was deferred through the issuance of notes payable that are to be repaid by June 30, 2026.
+Added: Skyline Builders Group Holding Ltd.
+Added: In August 2025, QLE completed the acquisition of a controlling interest in Skyline.
+Added: QLE entered into a Stock Purchase Agreement to purchase all 1,995,000 of Skyline's Class B Ordinary Shares for the aggregate purchase price of $1,000,000.
+Added: Additionally, QLE entered into a Securities Purchase Agreement to purchase (i) 454,794 Class A Ordinary Shares, (ii) a Prefunded Warrant to purchase 1,600,000 Class A Ordinary Shares at an exercise price of $0.0001 per share ("Prefunded Warrants"), (iii) a Class A Ordinary Share Purchase Warrant A to purchase up to 2,054,794 Class A Ordinary Shares at an exercise price of $0.60 per share ("A Warrant"), and (iv) a Class A Ordinary Share Purchase Warrant B to purchase 2,054,794 Class A Ordinary Shares at an exercise price of $0.65 per share ("B Warrant" and together with Prefunded Warrant and A Warrant, "Warrants"), for the aggregate purchase price of $1,500,000 ("Skyline Purchase Agreement").
+Added: Each Class A Ordinary Share shall entitle the holder thereof to one (1) vote on all matters subject to vote at general meetings of Skyline, and each Class B Ordinary Share shall entitle the holder thereof to twenty (20) votes on all matters subject to vote at general meetings of Skyline.
+Added: Currently there is no mechanism in which Class A Ordinary Shares are convertible into Class B Ordinary Shares.
+Added: Currently there is no mechanism in which Class B Ordinary Shares are convertible into Class A Ordinary Shares.
+Added: On the acquisition date, QLE became the holder of 79.14% of the aggregate voting power represented by all of Skyline's outstanding Class A Ordinary Shares and Class B Ordinary Shares, and thereby gaining control over Skyline.
+Added: Skyline is a holding company, and its operations are conducted through its wholly owned operating subsidiaries, Kin Chiu Engineering Limited and Kin Chiu Development Company Limited.
+Added: Operations primarily consist of construction activities which include public civil engineering works, such as road and drainage works, in Hong Kong.
+Added: Skyline mostly undertakes civil engineering works in the role as a subcontractor but is fully qualified to undertake such works in the capacity of a main contractor.
+Added: QLE intends to pursue opportunities to acquire assets in the critical materials supply chain.
+Added: Effective September 18, 2025, Dr.
+Added: Ryno Pretorius, Chief Executive Officer of QLE, was appointed as an independent director of Skyline.
+Added: In addition, an employee of ASP Isotopes was appointed as an independent director of Skyline.
+Added: Effective January 1, 2026, the Skyline board of directors appointed Paul Mann as Executive Chairman.
+Added: Effective March 31, 2026, the employee of ASP Isotopes that held one of the director positions at Skyline resigned was replaced by a new independent director.
+Added: On January 23, 2026, Skyline entered into a warrant exchange agreement (the “Skyline Exchange Agreement”) with the holders of Skyline Class A Ordinary Share Purchase Warrant A’s and Skyline Class A Ordinary Share Purchase Warrant B’s (collectively, the “Skyline Holder Warrants”), to purchase an aggregate of 48,698,628 Skyline Class A Ordinary Shares, that were purchased in the Skyline Series A Private Placement, to exchange the Skyline Holder Warrants issued on August 29, 2025, for an aggregate of 47,326,025 newly issued Series A preferred shares of Skyline (“Skyline Series A Preferred Shares”) and allotted among the holders in accordance with the Skyline Exchange Agreement.
+Added: Each Skyline Series A Preferred Share is convertible, at the option of a holder thereof, into Skyline Class A Ordinary Shares.
+Added: On February 11, 2026, Skyline entered into (i) a securities purchase agreement (the “Reg D Purchase Agreement”) for an offering of Skyline’s Series B Convertible Preferred Shares (the “Skyline Series B Preferred Shares”) in a private placement (the “Reg D Private Placement”) pursuant to Regulation D under the Securities Act of 1933, as amended and (ii) a securities purchase agreement (the “Reg S Purchase Agreement”) for an offering of the Skyline Series B Preferred Shares in a private placement pursuant to Regulation S under the Securities Act (the “Reg S Private Placement” and together with the Reg D Private Placement, the “February 2026 Skyline Series B Private Placements”), in each case, for the purchase and sale of the Skyline Series B Preferred Shares.
+Added: The February 2026 Skyline Series B Private Placements closed on February 13, 2026 at which Skyline issued 6,322 of the Skyline Series B Preferred Shares.
+Added: The purchase price for each Skyline Series B Preferred Share was $5,000.
+Added: Each Skyline Series B Preferred Share is convertible into Skyline Class A ordinary shares with a conversion price of $2.40 per share, subject to certain
+Added: anti-dilution adjustments that are subject to a floor of $1.50 per share and other customary adjustments for share splits, recapitalizations, reorganizations and similar transactions.
+Added: The gross proceeds of the Skyline Series B Private Placement were approximately $31.6 million, before deducting placement agent fees and other offering expenses payable by Skyline.
+Added: In connection with the February 2026 Skyline Series B Private Placements, Skyline also entered into placement agency agreements dated February 10, 2026 that included the payment of a cash fee equal to 8.0% of the aggregate gross proceeds of the February 2026 Skyline Series B Private Placements and the issuance of non-callable warrants exercisable for a number of Skyline's Class A Ordinary Shares equal to 6% of the Class A Ordinary Shares underlying the Skyline Series B Preferred Shares.
+Added: The warrants have an exercise price of $2.40 per share.
+Added: On March 20, 2026, Skyline entered into (i) a senior unsecured convertible note purchase agreement for an offering of approximately $16.6 million of Skyline's senior unsecured convertible notes (the “2026 Skyline Notes”) in a private placement and (ii) a securities purchase agreement dated March 20, 2026 for an offering of $0.6 million of Skyline’s Series B Preferred Shares (the “March 2026 Skyline Preferred Shares”) in a private placement (the "March 2026 Skyline Private Placement").
+Added: The March 2026 Skyline Private Placement closed on March 25, 2026.
+Added: The 2026 Skyline Notes are convertible into Skyline's class A ordinary shares, par value $0.00001 per share at a conversion price of $2.40 per share, subject to certain anti-dilution adjustments, that are subject to a floor of $1.50 per share.
+Added: The conversion price of the 2026 Skyline Notes is also subject to other customary adjustments for share splits, recapitalizations, reorganizations and similar transactions The purchase price for each March 2026 Skyline Preferred Share was $5,000.
+Added: Each March 2026 Skyline Preferred Share is convertible into Class A ordinary shares at a conversion price of $2.40 per share, subject to certain anti-dilution adjustments that are subject to a floor of $1.50 per share.
+Added: The gross proceeds of the March 2026 Skyline Private Placement was approximately $17.2 million, before deducting placement agent fees and other offering expenses that were paid by Skyline.
+Added: In connection with the March 2026 Skyline Private Placement, Skyline also entered into placement agency agreements dated March 20, 2026 that included the payment of a cash fee equal to 8.0% of the aggregate gross proceeds of the March 2026 Skyline Private Placement and the issuance of non-callable warrants exercisable for a number of Skyline's Class A Ordinary Shares equal to 8% and 6% of the Class A Ordinary Shares underlying the 2026 Skyline Notes and March 2026 Skyline Preferred Shares, respectively.
+Added: The warrants have an exercise price of $2.40 per share.
+Added: On March 29, 2026, QLE entered into a securities exchange agreement with an investor (the "QLE Exchange Agreement").
+Added: Per the QLE Exchange Agreement, the investor assigned and transferred 1,995,000 Class A Ordinary Shares held by the investor to QLE in exchange for an equal number of Class B Ordinary Shares held by QLE.
+Added: On March 31, 2026, Skyline issued an additional $3.0 million of 2026 Skyline Notes in a private placement.
+Added: Renergen Acquisition.
+Added: On January 6, 2026, ASP Isotopes acquired all of the issued and outstanding ordinary shares of Renergen (“Renergen Ordinary Shares”) from Renergen shareholders in exchange for shares of our common stock at an exchange ratio of 0.09196 shares of our common stock for each Renergen Ordinary Share (the “Consideration Shares”) through the implementation of a scheme of arrangement (the “Scheme”) in accordance with Sections 114 and 115 of the South African Companies Act, No.
+Added: 71 of 2008, resulting in the issuance of an aggregate of 14,270,000 Consideration Shares.
+Added: As a result of the transactions contemplated by the Scheme, the ordinary shares of Renergen, which were publicly traded on the Johannesburg Stock Exchange (JSE:
+Added: REN) and the Australian Securities Exchange (ASX:RLT), were delisted and Renergen became a wholly owned subsidiary of ASP Isotopes.
+Added: Renergen is South Africa’s leading onshore natural gas explorer and the first integrated producer of both liquid helium and LNG, both of which are produced from the large natural gas reserve base that underpins Renergen’s Virginia Gas Project.
+Added: The Virginia Gas Project includes (i) the liquefaction of natural gas into LNG, (ii) the separation of helium from natural gas, and (iii) the further liquefaction of helium into 99.999% pure liquid helium.
+Added: This liquefaction and separation takes place at the natural gas processing plant (the “Virginia Gas Plant”) in the Free State Province of South Africa.
+Added: Based on the drilled and flow-tested wells, Renergen’s average helium concentration exceeds 3.0%, which is well above typical conventional natural gas reservoirs containing helium in small concentrations (less than 0.5%).
+Added: In South Africa, petroleum production rights are issued by the South African Department of Mineral Resources and Energy (the “DMRE”) and serve as the mechanism through which all entities, mostly private, are granted the right to extract and sell hydrocarbons and associated coproducts.
+Added: The Petroleum Agency of South Africa is responsible for (i) promoting onshore and offshore exploration and production of petroleum;
+Added: (ii) receiving and evaluating applications for reconnaissance permits, technical cooperation permits, exploration rights and production rights;
+Added: and (iii) making recommendations on such applications to the Minister of Mineral Resources and Energy.
+Added: South African production rights are valid for 30 years and are renewable for further periods, each of which must not exceed 30 years at a time in respect of each renewal, provided that the holder can justify that it can continue production operations.
+Added: Production rights may be encumbered by mortgages for the purposes of raising debt financing.
+Added: Renergen’s principal asset is its 94.5% equity ownership in Tetra4, which holds South Africa’s first and only onshore petroleum production right (the “Production Right”) and is the entity developing the Virginia Gas Project.
+Added: Our Production Right is currently valid through September 20, 2042 and renewable for an additional 30-year period thereafter.
+Added: The Virginia Gas Project
+Added: spans an area of over 187,000 hectares (over 462,000 acres) in the Free State Province approximately 250 kilometers (155 miles) southwest of Johannesburg, where natural gas-emitting boreholes were discovered through other mineral exploration activities.
+Added: We have confirmed our Production Right as a major global helium resource with an average helium concentration of over 3% based on drilled and flow-tested wells.
+Added: Additionally, the purity of our natural gas is high, with an average of over 90% natural gas and almost zero percent higher alkanes or sulphur, reducing the complexity and cost of liquefaction.
+Added: The remaining approximately 7% of our production is nitrogen, which is utilized to separate the helium from the natural gas stream in Phase 1 of the Virginia Gas Project (“Phase 1”) production process.
+Added: We receive an economic advantage from this coproduced nitrogen source, as it would otherwise have to be sourced externally to separate the helium from the natural gas stream.
+Added: In addition to our Production Right, the South African government also granted us petroleum exploration rights (“Exploration Rights”).
+Added: Exploration Rights allow the holder to carry out the entire value chain of petroleum exploration such as acquisition and processing of new geological/geophysical data, reprocessing of existing geological/geophysical data and any other related activity to define a trap to be tested by drilling, logging and testing, including well appraisal activities.
+Added: The Exploration Rights correspond to our operations in the Free State Province and are expected to contain significant helium and natural gas resources exceeding the scope of the Virginia Gas Project.
+Added: Our Exploration Rights were set to expire on August 23, 2024.
+Added: However, we submitted an application to incorporate the Exploration Rights into our Production Right, by means of an amendment to the Production Right in accordance with Section 102 of the South African Mineral and Petroleum Resources Development Act 28 of 2002 (“MPRDA”), which we expect will extend our ability to carry out petroleum exploration activities through the expiration date of our Production Right.
+Added: Our application was submitted on July 16, 2024 and the application was authorized on May 9, 2025.
+Added: Following the authorization, two appeals were made by various parties and the appeal process is ongoing.
+Added: We expect the appeal process to be resolved in 2027.
+Added: Phase 1 has commenced commercial LNG operations.
+Added: Phase 1 drilling of wells to reach the required cumulative nameplate flow rate is now complete.
+Added: The gas gathering and tie in connections for these wells is ongoing.
+Added: Once the tie in connections are complete the facility is expected to operate at maximum production capacity and include liquid helium operations.
+Added: Phase 1 serves as both proof of concept for the larger development that will be Phase 2 of the Virginia Gas Project (“Phase 2”), and sales and revenue generation to establish a foundational customer base and foster customer relationships.
+Added: The Virginia Gas Project benefits from favorable supply and demand trends in both the LNG and liquid helium sectors.
+Added: The LNG is and will continue to be sold domestically in South Africa into a market suffering energy and natural gas shortages, and we plan to sell helium directly to global customers at a time when the world is suffering helium supply shortages, which have been further exacerbated by the ongoing United States-Israel-Iran war.
+Added: We believe that it was for these two reasons that the Virginia Gas Project was conditionally approved to be funded by the U.S.
+Added: International Development Finance Corporation (“DFC”) as part of the U.S.’s initiative to ensure new helium supply comes online as aerospace and the semiconductor industry increase helium requirements in the face of diminished supply, while increasing South Africa’s domestic energy supply.
+Added: Helium is a vital and irreplaceable element in many modern industries because it is both chemically and electrically inert and, when in liquid form, is the coldest substance known to man at 3 degrees Kelvin (minus 454.3 degrees Fahrenheit).
+Added: For these reasons, it can be used in the manufacture of semiconductors, to purge laboratory or manufacturing environments, act as a fuel propellant for other cryogenic fuels, and/or provide deep cryogenic cooling.
+Added: It is commonly used in space exploration and rocketry, high-level physics experiments (e.g., particle accelerators, quantum mechanics), medical science within MRI devices, fiber optic cable production, commercial diving gas, specialized welding, coolant for nuclear power stations and lifting balloons.
+Added: We believe that Renergen’s LNG supply can play an important role in reducing South Africa's relatively high carbon emissions by being the first, and currently the only, LNG supplier in the country.
+Added: According to Energy Institute (2024), coal has a 69% share of national primary energy consumption, with gas only around 3.5%.
+Added: As such, according to the World Bank, South Africa ranks as the fifth-worst carbon emissions country per kilogram per purchasing power parity of gross domestic product (“GDP”).
+Added: This ranking is largely due to South Africa’s high reliance on low-grade coal to provide electricity, supplemented by Sasol’s use of coal to liquids technology.
+Added: Sasol Limited is one of the country’s largest energy suppliers and operator of the natural gas pipeline supplying gas from Mozambique into Johannesburg.
+Added: LNG is a significantly lower carbon-emitting fuel than either of coal (by 50%) and diesel (25%), upon combustion.
+Added: Therefore, the introduction of Renergen’s LNG into South Africa’s energy supply mix, including the possible direct substitution of Renergen’s LNG for first diesel, and then potentially coal, may help reduce South Africa’s overall carbon emissions intensity as the country moves towards its net zero carbon emissions targets by 2050.
+Added: Investments in Early Stage Drug Development Companies
+Added: On July 28, 2025, we purchased 2,000,000 shares of IsoBio, Inc.
+Added: (“IsoBio”) Series Seed-1 Preferred Stock at $2.50 per share for a total aggregate purchase price of $5.0 million.
+Added: IsoBio is a U.S.-based radiotherapeutic development company focused on developing a broad pipeline of mAb-based radioisotope therapeutics targeting both derisked and novel tumor antigens for patients in need of new cancer therapies.
+Added: As the owner of the Series Seed-1 Preferred Stock, we have the right to designate one board member.
+Added: An officer and director of ours was designated to fill that board seat.
+Added: In addition, another board member of ours is a board member and executive officer of IsoBio.
+Added: On January 26, 2026, we purchased 4,356,918 shares of Opeongo, Inc.
+Added: (“Opeongo”) Series Seed-1 Preferred Stock at $2.2952 per share for a total aggregate purchase price of $10.0 million.
+Added: Opeongo is a biotechnology company developing novel therapeutics using extracellular matrix modulation to target fibrosis, inflammation, and cancer.
+Added: Opeongo was co-founded by David Baram, Ph.D.
+Added: who serves as Opeongo’s Chief Executive Officer and director.
+Added: As the owner of the Series Seed-1 Preferred Stock, we have the right to designate one board member.
+Added: An officer and director of ours was designated to fill that board seat.
+Added: In addition, another board member of ours is a board member and executive officer of Opeongo.
+Added: Skyline Investments
+Added: Skyline Reemag Investment.
+Added: In November 2025, Skyline acquired a 13.09% ownership of Reemag LLC ("Reemag") for a cash purchase price of $3.0 million.
+Added: Skyline will subscribe for additional membership interests of Reemag in tranches, resulting in ownership percentages of 13.09%, 20.06%, 33.42% and 50.10% at the initial, second, third and fourth closing respectively for an aggregate purchase price of $20.0 million.
+Added: The second, third and fourth closings were scheduled on or before January 31, 2026, March 31, 2026 and by the earlier of a $200.0 million capital raise or July 31, 2026, respectively.
+Added: However, in March 2026, Skyline entered into the first amendment to the subscription agreement with Reemag that amended the dates of the second, third and fourth closings to May 31, 2026, July 31, 2026 and September 30, 2026, respectively.
+Added: Skyline Critical Minerals Space Investment.
+Added: On October 31, 2025, Skyline entered into a subscription and unit purchase agreement with a limited liability company engaged in the critical minerals space, pursuant to which Skyline subscribed for an approximate 20% membership interest in such company for a subscription price of $20.0 million.
+Added: Agreements with TerraPower LLC
+Added: On April 4, 2024, we entered into an agreement with TerraPower to develop a conceptual design, refined cost/schedule/financing, risk register, and term sheet for a HALEU facility (the “TerraPower Agreement”).
+Added: The TerraPower Agreement may be terminated for (a) breach or default, (b) our convenience or (c) TerraPower’s convenience.
+Added: TerraPower is obligated to make all payments for milestones completed by us and these payments are nonrefundable.
+Added: On October 18, 2024, we signed a term sheet with TerraPower (the “TerraPower Term Sheet”) that provides for the execution of two definitive agreements:
+Added: (1) an agreement pursuant to which TerraPower will provide funding for our construction of a uranium enrichment facility capable of producing HALEU using our proprietary aerodynamic separation process technology to be located in the Republic of South Africa and (2) an agreement pursuant to which we will deliver to TerraPower the full capacity of the enrichment facility.
+Added: In May 2025, we entered into a Loan Agreement with TerraPower (the “TerraPower Loan Agreement”), which provides conditional commitments from TerraPower to us through one of our wholly-owned U.S.-based subsidiaries for a multiple advance term loan totaling $22.0 million for the purpose of partially funding the construction of a proposed new uranium enrichment facility in South Africa.
+Added: The total loan amount is inclusive of a 10% original issue discount on each disbursement and carries a fixed interest rate of 10% per annum.
+Added: Per the terms of the TerraPower Loan Agreement and subject to the satisfaction of various conditions precedent to disbursements (including receiving all required licenses and permits to perform uranium enrichment in South Africa), we will receive aggregate loan disbursements of $20.0 million.
+Added: Such loan matures on May 16, 2032.
+Added: Interest will begin accruing upon each milestone disbursement we receive and will be added to the principal balance until November 2027.
+Added: Principal and interest payments will be made in 60 equal installments beginning in November 2027.
+Added: We plan to request drawdowns on this loan beginning in the third quarter of 2026.
+Added: In addition to the TerraPower Loan Agreement, in May 2025, we and TerraPower have entered into two supply agreements for the HALEU expected to be produced at our uranium enrichment facility.
+Added: The initial core supply agreement is intended to support the supply of the required first fuel cores for the initial loading of TerraPower’s Natrium project in Wyoming.
+Added: The long-term supply agreement is a 10-year supply agreement of up to a total of 150 metric tons of HALEU, commencing in 2028 through end of 2037.
+Added: Beginning in 2024, primarily as a result of the increased business activities of our subsidiary, QLE, we had two operating segments:
(i) nuclear fuels, and (ii) specialist isotopes and related services.
+Added: Beginning in August 2025, primarily as a result of the acquisition of Skyline, we have three operating segments:
+Added: (i) nuclear fuels, (ii) specialist isotopes and related services, and (iii) construction services:
• Nuclear Fuels.
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• Specialist Isotopes and Related Services.
−Removed: This segment is focused on research and development of technologies and methods used to separate high-value, low-volume isotopes (such as C-14, Mo-100 and Si-28) for highly specialized target end markets other than advanced nuclear fuels, including pharmaceuticals and agrochemicals, nuclear medical imaging and semiconductors, as well as services related to these isotopes, and this segment includes PET Labs.
+Added: This segment is focused on research and development of technologies and methods used to separate high-value, low-volume isotopes (such as C-14, Si-28 and Yb-176) for highly specialized target end markets other than advanced nuclear fuels, including pharmaceuticals and agrochemicals, nuclear medical imaging and semiconductors, as well as services related to these isotopes, and this segment includes PET Labs.
+Added: • Construction Services.
+Added: This segment is focused on public civil engineering services in Hong Kong, such as road and drainage works which includes construction of footway, drain, ducts, and pipelines.
+Added: In executing these projects, we may be required to perform a range of activities including to (i) clear the construction site and make demolition of existing structures;
+Added: (ii) install concrete and reinforcing steel bars;
+Added: (iii) conduct excavation, deposition, disposal and compaction of fill material;
+Added: and (iv) plant trees, plants, irrigation system and general establishment works.
Commence commercial production at each of our enrichment facilities in Pretoria, South Africa.
We commenced commercial production of enriched isotopes at our ASP enrichment facilities located in Pretoria, South Africa during the first quarter of 2025.
−Removed: Our first ASP enrichment facility is designed to enrich light isotopes, such as Carbon-14.
−Removed: The second ASP enrichment facility, which is substantially larger than the first, should have the potential to enrich kilogram quantities of relatively heavier isotopes, including but not limited to Silicon-28 and Molybdenum-100.
−Removed: We anticipate shipping the first commercial batches of enriched Carbon-14 in mid-2025 and enriched Silicon-28 during the second quarter of 2025.
−Removed: We are in the process of commissioning and commencing commercial production at our third enrichment facility, a QE technology facility, which will be our first laser-based enrichment plant and is expected to be able to achieve a 99.75% enrichment for Ytterbium-176.
−Removed: We expect to commence commercial production of Ytterbium-176 during the second quarter of 2025.
+Added: Our first ASP enrichment facility is designed to enrich light isotopes, such as C-14.
+Added: The second ASP enrichment facility, which is substantially larger than the first, should have the potential to enrich kilogram quantities of relatively heavier isotopes, including but not limited to Si-28 and Mo-100.
+Added: We are targeting initial commercial shipments of enriched C-14 in mid-2026 and initial commercial shipments of enriched Si-28 during the second quarter of 2026.
+Added: We have also completed the commissioning phase and are producing commercial samples of highly enriched Yb-176 at our third enrichment facility, a QE technology facility, which will be our first laser-based enrichment plant.
+Added: We are targeting initial commercial shipments of Yb-176 in mid-2026 or the third quarter of 2026.
Demonstrate the capability to produce commercial quantities of enriched C-14, Si-28 and Yb-176 using the ASP and QE technologies and capitalize on the opportunity to solve many supply chain challenges that currently exist.
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Other electronic gasses that can likely be enriched using ASP technology include disilane and germane.
−Removed: Enriched Ytterbium-176 can be irradiated to produce Lutetium-177, which has been identified for use in oncology, particularly in targeted radionuclide therapy ("TRT").
+Added: Enriched Yb-176 can be irradiated to produce Lutetium-177, which has been identified for use in oncology, particularly in targeted radionuclide therapy ("TRT").
TRT is used in the treatment of various types of cancers, including neuroendocrine tumors, prostate cancer, and bone metastases, among others.
There are numerous ongoing clinical trials studying Lutetium-177 PSMA-617 in patients with metastatic castration-resistant prostate cancer.
−Removed: We have obtained all necessary licenses within South Africa to proceed with the commercial development of this product.
+Added: We believe we have obtained all necessary licenses within South Africa to proceed with the commercial development of this product.
Continue identifying potential offtake customers and strategic partners for our enriched isotopes.
−Removed: We have significant interest from potential offtake customers for the enriched isotopes that we intend to produce.
+Added: We currently have no sales attributable to enriched isotopes, but we have significant interest from potential offtake customers for the enriched isotopes that we intend to produce.
In June 2023, we entered into a tolling agreement with a Canadian customer for the entire capacity of our C-14 production facility.
−Removed: In April and June 2024, we entered into purchase orders with a US semiconductor company and a global industrial gas company for the supply of highly enriched silicon-28.
+Added: In April and June 2024, we entered into purchase orders with a US semiconductor company and a global industrial gas company for the supply of highly enriched Si-28.
We are currently in discussions with potential customers that have an interest in entering into long-term supply agreements for kilogram quantities of Si-28 and larger quantities of Xe-129, Ge 72, Ge-74, Zn-68, and Cl-37.
We intend to identify additional potential customers and strategic partners for isotopes that we may produce at our existing and planned enrichment facilities.
−Removed: Demonstrate the capability to produce high-assay low-enriched uranium (HALEU) using our enrichment technologies and meet anticipated demand for the new generation of HALEU-fueled small modular reactors and advanced reactor designs that are now under development for commercial and government uses.
−Removed: We plan to begin research and development for the enrichment of uranium to demonstrate our capability to produce HALEU using Quantum Enrichment technology.
−Removed: We anticipate a future demand for HALEU for the new generation of HALEU-fueled small modular reactors ("SMRs") and advanced reactor designs that are now under development for commercial and government uses.
+Added: Demonstrate the capability to produce HALEU using our enrichment technologies and meet anticipated demand for the new generation of HALEU-fueled small modular reactors and advanced reactor designs that are now under development for commercial and government uses.
+Added: We plan to begin research and development for the enrichment of uranium to demonstrate our capability to produce HALEU using QE technology.
+Added: We anticipate a future demand for HALEU for the new generation of HALEU-fueled SMRs and advanced reactor designs that are now under development for commercial and government uses.
SMRs are viewed as being cheaper, safer, and more versatile than traditional large-scale nuclear reactors, and development of the new technology is receiving considerable funding from the U.S.
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and the United Kingdom.
−Removed: We are currently in discussions with nuclear regulatory authorities in multiple countries, including the UK Atomic Energy Authority, UK Office of Nuclear Regulation (ONR), Nuclear Energy Corporation of South Africa (NECSA), the South African Department of Mineral Resources and Energy (DMRE), United States Department of Energy (DOE) and the United States Nuclear Regulatory Commission (NRC), regarding the construction of a nuclear fuel plant in these countries.
+Added: We are currently in discussions with nuclear regulatory
+Added: authorities in multiple countries, including the UK Atomic Energy Authority, UK Office of Nuclear Regulation (UK ONR), Necsa, the DMRE, United States Department of Energy (DOE) and the United States Nuclear Regulatory Commission (NRC), regarding the construction of a nuclear fuel plant in these countries.
+Added: In the period since our inception to date, we have not applied our enrichment technologies to the enrichment of U-235, nor received permission or regulatory approval to conduct testing of our enrichment technologies on U-235, except for the activities contemplated by the Services Contract with Necsa (described in the next paragraph).
+Added: Our expectation that QLE’s initiative to apply our enrichment technologies to the enrichment of U-235 could be successful is based upon research conducted by certain of our scientists prior to joining the company, as well as the demonstrated effectiveness of QE technology on Yb-176.
We intend to progress our uranium enrichment initiative first in South Africa.
−Removed: In November 2024, we entered into a Memorandum of Understanding ("MOU") with The South African Nuclear Energy Corporation (Necsa) to collaborate on the research, development and ultimately the commercial production of advanced nuclear fuels.
+Added: In November 2024, we entered into a Memorandum of Understanding ("MOU") with Necsa to collaborate on the research, development and ultimately the commercial production of advanced nuclear fuels.
Necsa is a state-owned company established by the Republic of South Africa Nuclear Energy Act in 1999 with a mandate to undertake and promote research and development in the field of nuclear energy and radiation sciences.
Necsa is also responsible for processing source material, and co-operating with other institutions on nuclear and related matters.
−Removed: The proposed structure under discussion for the delivery of the objectives of the MOU contemplates the formation of a new entity in South Africa with a board of directors consisting of at least two representatives from ASPI and Necsa.
−Removed: It is anticipated that the research, development and ultimate construction of a HALEU production facility will take place at South Africa’s main nuclear research center located at Pelindaba, Pretoria.
−Removed: Alongside our talks with regulators, we are currently discussing with multiple counterparties engaged in the development of SMR reactors to produce HALEU to further their research efforts and future commercial endeavors.
−Removed: We have entered into two MOUs with US-based SMR companies for the supply of HALEU.
−Removed: For example, our term sheet with TerraPower, LLC which contemplates the parties entering into definitive agreements pursuant to which TerraPower would provide funding for the construction of a HALEU production facility and agree to purchase all HALEU produced at the facility over a 10-year period after the planned completion of the facility in 2027.
+Added: In February 2026, QLE South Africa and Necsa entered into a Services Contract as part of the collaboration contemplated by the MOU.
+Added: Under the Services Contract, Necsa has agreed to provide to QLE South Africa certain facilities, infrastructure, utilities and services related to the siting, design, construction, commission and operation of an enrichment facility on the Necsa site in Pelindaba.
+Added: A Joint Coordination Committee, to be comprised of two representatives of QLE South Africa and Necsa, has been established to oversee and govern the implementation of the Services Contract.
+Added: In March 2026, QLE UK entered into an agreement with the University of Bristol related to the design of a state-of-the-art lithium laser research facility in the UK.
+Added: Under the terms of the agreement, the University of Bristol is expected to lead the design and feasibility study for a site-agnostic laser enrichment research facility over an estimated four-month initial phase.
+Added: The project involves comprehensive desk-based concept design work, detailed engineering specifications, and safety reviews to establish the foundation for what could become a groundbreaking research hub.
+Added: The University of Bristol is expected to coordinate a comprehensive team of specialists, including experts in mechanical, electrical, and plumbing specification, structural engineering, architecture, construction project management, pyrophoric lithium handling, and laser safety.
+Added: The project is expected to progress through multiple phases, including documentation review, safety assessments, cell design development, and detailed facility design work culminating in RIBA Stage 4 (Technical Design) completion.
+Added: Subject to a positive feasibility assessment, the parties intend to proceed with construction of the facility at a suitable University of Bristol site off-campus where it will be planned to enable cutting-edge research commissioned and funded by QLE.
+Added: QLE’s UK program of work has been developed in consultation with key UK government and regulatory bodies, including the UK Department for Energy Security and Net Zero, the UK Atomic Energy Authority, the UK ONR, and the UK Environment Agency.
+Added: Alongside our talks with regulators, we have entered into agreements or are currently discussing with multiple counterparties engaged in the development of SMR reactors to produce HALEU to further their research efforts and future commercial endeavors.
+Added: For example, in May 2025, we entered into the TerraPower Loan Agreement, which provides conditional commitments from TerraPower to us through one of our wholly-owned U.S.-based subsidiaries for a multiple advance term loan totaling $22,000,000 for the purpose of partially funding the construction of a proposed new uranium enrichment facility in South Africa.
+Added: Per the terms of the TerraPower Loan Agreement and subject to the satisfaction of various conditions precedent to disbursements (including receiving all required licenses and permits to perform uranium enrichment in South Africa), we will receive aggregate loan disbursements of $20,000,000.
+Added: We plan to request an initial drawdown on this loan during 2026 when construction of the uranium enrichment facility is expected to begin.
+Added: In addition to the TerraPower Loan Agreement, in May 2025, we and TerraPower entered into two supply agreements for the HALEU expected to be produced at our uranium enrichment facility in South Africa.
+Added: The initial core supply agreement is intended to support the supply of the required first fuel cores for the initial loading of TerraPower’s Natrium project in Wyoming.
+Added: The long-term supply agreement is a 10-year supply agreement of up to a total of 150 metric tons of HALEU, commencing in 2028 through end of 2037.
Demonstrate the effectiveness and value in the use of stable isotopes in the downstream radiopharmacy market, after acquiring 51% ownership interest in PET Labs, the leading radiopharmacy in South Africa.
This investment will address the radioisotope needs of South Africa as well as certain neighboring countries.
−Removed: Under the terms of a Share Purchase Agreement, dated October 30, 2023, we acquired 51% of the issued share capital of PET Labs Pharmaceuticals Proprietary Limited, a company incorporated in the Republic of South Africa (“PET Labs”).
−Removed: PET Labs is a South African radiopharmaceutical operations company, dedicated to nuclear medicine and the science of radiopharmaceutical
+Added: Under the terms of a Share Purchase Agreement, dated October 30, 2023, we acquired 51% of the issued share capital of PET Labs, a company incorporated in the Republic of South Africa.
+Added: PET Labs is a South African radiopharmaceutical operations company, dedicated to nuclear medicine and the science of radiopharmaceutical production.
As a result of this transaction, we entered into the downstream radiopharmacy market that we intend to service in the future.
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We intend to expand PET Labs’ existing operations by adding two new cyclotrons to its service footprint, enabling the company to properly expand its other revenue generation mediums, which is anticipated to drive free cash flow to the company.
−Removed: Our Strengths
−Removed: ASP technology initially developed by Klydon and further developed by ASP Isotopes Inc..
−Removed: The aerodynamic separation technique has its origins in the South African uranium enrichment program in the 1980s, and the ASP technology had been developed during the last two decades by the scientists at Klydon.
−Removed: The scientists at Klydon had constructed two ASP plants for the enrichment of oxygen-18 and silicon-28 in Pretoria, South Africa, which were commissioned in October 2015 and July 2018, respectively.
−Removed: While the technology has not yet been used to enrich either Uranium or heavier isotopes, we believe the success of the enrichment process for oxygen-18 and silicon-28 has demonstrated the efficacy and commercial scalability of the ASP technology.
−Removed: If our research and development is successful (and subject to obtaining applicable regulatory approvals and appropriate licenses), we plan to commercialize many different isotopes produced using the ASP technology.
−Removed: To date, we have not produced commercial quantities of any enriched isotopes and we have not demonstrated the ability to produce any enriched isotopes in commercial quantities using ASP technology.
−Removed: Extensive Research and Development Experience in Aerodynamic Separation Technology and Processes.
−Removed: Subject to successful research and development, our ASP technology has the potential to produce many different types of isotopes.
−Removed: Klydon had spent the last two decades and tens of millions of dollars developing the aerodynamic separation technique used in the ASP technology, generating critical trade secrets.
+Added: Develop world class helium reserves at Virginia Gas Project.
+Added: The Virginia Gas Project contains high purity natural gas and is one of the richest concentrations of helium globally.
+Added: Some wells contain up to 12% helium concentration in recorded tests, and based on the drilled and tested flow rates, our average helium concentration exceeds 3%, which compares with the average concentrations of Qatar at 0.05%, Russia at 0.06% and the USA at 0.35%.
+Added: The LNG is and will continue to be sold domestically in South Africa into a market suffering energy and natural gas shortages, and we plan to sell the helium directly to global customers at a time when the world is suffering helium supply shortages, which have been further exacerbated by the ongoing United States-Israel-Iran war.
+Added: Capitalize on the Acquisition of a Controlling Interest in Skyline Builders Group Holding Limited.
+Added: On August 29, 2025, QLE became a controlling shareholder of Skyline Builders Group Holding Limited, a company incorporated under the laws of the Cayman Islands (“SKBL”) with its Class A Ordinary Shares listed on The Nasdaq Stock Market LLC (“Nasdaq”) under the symbol “SKBL.” QLE invested in SKBL’s Class A Ordinary Shares, Class B Ordinary Shares and warrants to purchase Class A Ordinary Shares for the aggregate purchase price of $2.5 million.
+Added: Each warrant is immediately exercisable and entitles the holder to acquire Class A Ordinary Shares for a period of five years following August 29, 2025.
+Added: QLE, as a holder of warrants, does not have the right to exercise any portion of any warrant, to the extent that QLE (together with the holder’s affiliates) would beneficially own in excess of 9.99% of the number of Class A Ordinary Shares outstanding immediately after giving effect to the exercise of the applicable warrant.
+Added: As of the date of this annual report on Form 10-K, QLE is the holder of 4.74% of the aggregate voting power represented by all outstanding Class A Ordinary Shares and Class B Ordinary Shares of SKBL.
+Added: In addition, on August 29, 2025, Paul Mann, our Chairman and Chief Executive Officer and Chairman of the Board of Managers of QLE, purchased, for the aggregate purchase price of $2.5 million, as an individual investor:
+Added: Class A Ordinary Shares and certain warrants to purchase Class A Ordinary Shares of SKBL on the same terms as QLE’s investment in Class A Ordinary Shares and warrants, provided that Mr.
+Added: Mann, as a holder of warrants, does not have the right to exercise any portion of any warrant, to the extent that such holder (together with the holder’s affiliates) would beneficially own in excess of 4.99% of the number of Class A Ordinary Shares outstanding immediately after giving effect to the exercise of the applicable warrant.
+Added: Radioisotopes and Chemical Elements Competition
+Added: The development and commercialization of radioisotopes and chemical elements is highly competitive.
+Added: We face competition with respect to all the enriched isotopes that we may produce using our ASP technology from established biotechnology and nuclear medicine technology companies and will face competition with respect to enriched uranium that we may seek to develop or commercialize in the future from innovative technology and energy companies.
+Added: There are a number of large biotechnology and nuclear medicine technology companies that currently market and sell radioisotopes to radiopharmacies, hospitals, clinics and others in the medical community (Mo-99 is the active ingredient for Tc-99m-based radiopharmaceuticals used in nuclear medicine procedures).
+Added: There are also a number of technology and energy companies that are currently seeking to develop HALEU.
+Added: Potential competitors also include academic institutions, government agencies and other public and private research organizations that conduct research, seek patent protection and establish collaborative arrangements for research, development, manufacturing and commercialization.
We believe our competitors lag behind us in terms of the technical expertise of our senior management and the know-how contained in the aerodynamic separation technique, and will be unable to replicate the expected results of the ASP technology, even as we expect to continue to improve the existing technology and processes.
Additionally, the high capital costs of development of proprietary technologies, significant lead times required to construct new enrichment facilities, as well as stringent regulatory and operating requirements applicable to enrichment facilities, adds to the significant barriers to entry for smaller competing market participants.
−Removed: ASP technology is a flexible platform with the potential to produce many different isotopes that could serve large addressable markets.
−Removed: ASP technology is a flexible platform, compact in size and weight, and could be easily scaled to an industrial level with number of separation devices added in parallel.
−Removed: The ASP technology also has few moving parts, with low capital and operating costs in comparison to alternatives.
−Removed: The technology is particularly efficient at enriching isotopes of low atomic mass.
−Removed: We believe that, assuming receipt of required regulatory approvals and governmental permits, the ASP technology can be deployed quickly and with a relatively minimal capital cost, to enrich many different isotopes that we believe consumers require both today and in the future in end markets such as healthcare, technology and energy.
−Removed: The ASP technology is designed to be scalable, low cost, low energy, and environmentally friendly, with no radioactive waste or hazardous materials produced in the process and planned arrangements to reuse chemical by-products.
−Removed: QE technology has the potential to produce many different enriched isotopes that cannot be enriched using ASP Technology.
−Removed: Our QE technology is potentially a highly efficacious enrichment technology with the greatest enrichment factor of any enrichment process.
−Removed: In laboratory tests our scientists have achieved enrichment factors of up to 678 which compares to enrichment factors of less than 50 for AVLIS and 1.15 for a traditional centrifuge.
−Removed: QE can also be used to enrich elements where there is no known gaseous form of that element.
−Removed: We have completed the construction of our first QE enrichment facility in Pretoria, South Africa where we intend to produce 99.75% enriched Ytterbium-176.
−Removed: Experienced team
−Removed: Our board of directors and advisers have specialized expertise in isotope enrichment, research and development, technology, plant development, and manufacturing.
−Removed: Dr Hendrik Strydom, our chief technology officer and one of our directors, previously co-founded Klydon and has over 40 years of experience in isotope enrichment and laser design and manufacture.
−Removed: The scientific team that joined our company from Klydon combined has decades of experience in research and development of isotope enrichment and amassed deep knowledge in the field.
−Removed: Our board of directors and our management team also have broad experience and successful track records in fusion technology and fusion materials, biopharmaceutical research, chemicals, manufacturing and commercialization, as well as in business, operations, and finance.
−Removed: Our board of directors’ and management team’s experience was gained at leading companies and financial institutions that include, Bear Stearns, Deutsche Bank, Highbridge Capital, Investec Bank, Morgan Stanley and Soros Fund Management.
+Added: LNG and Helium Competition
+Added: The South African gas market has historically been stagnant and almost entirely dependent on local production of liquefied petroleum gas (“LPG”) and natural gas imported from Mozambique.
+Added: There are frequent constraints in LPG supply in South Africa.
+Added: Natural gas imported from Mozambique comes via the Republic of Mozambique Pipeline Company pipeline to Johannesburg and is supplied mainly to users close to the pipeline at low pressures.
+Added: In addition to LPG, South Africa relies primarily on coal for electricity generation.
+Added: Currently, only approximately 3% of South Africa’s energy mix comes from natural gas.
+Added: The current source of natural gas and coal supply is unable to fully supply existing energy demand.
+Added: As the holder of South Africa’s first and only onshore petroleum Production Right, we believe our biggest competition for our LNG includes producers and distributors of LPG, including the Republic of Mozambique Pipeline Company, and producers of other fuel sources such as compressed natural gas and coal.
+Added: Additionally, although South Africa has historically not imported LNG from outside of the continent, South Africa received its first import of LNG in November 2021 in the port of Ngqura.
+Added: In the future, we may face geographic competition if other companies are granted Exploration Rights or Production Rights in South Africa and begin producing LNG, or if such companies
+Added: import LNG from external sources outside of the continent due to grants of rights to import LNG into South Africa.
+Added: However, we believe that our position as the sole LNG provider in South Africa allows us a competitive advantage in the local LNG market, particularly as customers transition to LNG as a liquid fuel substitution of choice.
+Added: Helium is sold as a globally traded commodity, which is currently in tight supply and disruptions in the helium market can easily create shortages.
+Added: Helium has traditionally been traded on long-term private contracts, keeping prices opaque and reducing incentives for helium exploration.
+Added: The entire global helium supply is produced by approximately 30 liquefaction plants, located in the United States, Poland, Russia, Algeria, Qatar and China, among other locations.
+Added: A smaller number of players control the distribution of helium, which is often subject to privately negotiated contracts.
+Added: Location is often a primary competitive factor as the difficulties associated with transporting helium limit the distance it can be transported.
+Added: We believe we compare favorably with many of our helium competitors due our geographic location near the Cape of Good Hope, which we believe will allow us to provide helium to parts of the world that other competitors, such as companies located in Qatar, cannot.
+Added: Additionally, helium becomes more economically viable to extract from natural gas at higher concentrations.
+Added: We believe we compare favorably with many of our competitors due to the high concentration of helium in the Virginia Gas Project relative to our competitors.
+Added: Competitive conditions may be substantially affected by various forms of energy legislation and/or regulation considered from time to time by the South African government.
+Added: Our larger or more integrated competitors may be able to absorb the burden of existing, and any changes to, international, federal, state and local laws and regulations more easily than we can, which would adversely affect our competitive position.
+Added: Additionally, other countries may not impose similar laws or regulations on the production of helium.
+Added: It is not possible to predict the nature of any such legislation or regulation that may ultimately be adopted or its effects upon our future operations.
+Added: Such laws and regulations may substantially increase the costs of exploring for, developing or producing natural gas and helium, and may prevent or delay the commencement or continuation of a given operation.
+Added: The effect of these risks cannot be accurately predicted.
Technical Background
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Uranium is a naturally occurring radioactive element that has no stable isotope.
−Removed: It has two primordial isotopes, uranium-238 and uranium-235, which have long half-lives and are found in appreciable quantity in the Earth’s crust.
+Added: It has two primordial isotopes, uranium-238 (“U-238”) and U-235, which have long half-lives and are found in appreciable quantity in the Earth’s crust.
The decay product, uranium-234 is also found.
8 unchanged sentences
During the last century, a number of different methods have been developed to separate and enrich isotopes.
−Removed: The current separation or
−Removed: enrichment processes are based either on the atomic weight of the isotope, small differences in chemical reaction rates produced by different atomic weights or are based on properties not directly connected to atomic weight such as nuclear resonances.
+Added: The current separation or enrichment processes are based either on the atomic weight of the isotope, small differences in chemical reaction rates produced by different atomic weights or are based on properties not directly connected to atomic weight such as nuclear resonances.
Often performed on gases, but also on liquids, the diffusion method relies on the fact that in thermal equilibrium, two isotopes with the same energy will have different average velocities.
22 unchanged sentences
The resonant absorption of light for an isotope is dependent upon its mass and certain hyperfine interactions between electrons and the nucleus, allowing finely tuned lasers to interact with only one isotope.
−Removed: After the atom is ionized it can be removed from the sample by applying an electric field.
+Added: After the atom is ionized it can be removed
+Added: from the sample by applying an electric field.
This method is often abbreviated as AVLIS (atomic vapor laser isotope separation).
8 unchanged sentences
The heavier isotopes sink and the lighter isotopes rise, where they are easily collected.
−Removed: The Aerodynamic Separation Process ("ASP") Technology
−Removed: ASP technology is proprietary technology originally licensed from Klydon which succeeds earlier work, first detailed in the scientific media in the mid-1970s, relating to an industrial scale enrichment plant for uranium that was constructed utilizing the so-called “stationary-wall centrifuge”.
−Removed: The original technology was highly energy consuming and was not able to compete on an economic basis with other methods of isotope separation.
+Added: The ASP Technology
+Added: ASP technology is proprietary technology originally licensed from Klydon which succeeds earlier work, first detailed in the scientific media in the mid-1970s, relating to an industrial scale enrichment plant for uranium that was constructed utilizing the so-called “stationary-wall centrifuge.” The original technology was highly energy consuming and was not able to compete on an economic basis with other methods of isotope separation.
The innovative development of the ASP technology over the past two decades has culminated in a more advanced separation device that we believe can compete on a commercial scale with other methods of isotope separation.
65 unchanged sentences
ASP Technology In Use
−Removed: The scientists at Klydon had constructed two ASP plants for the enrichment of oxygen-18 and silicon-28 in Pretoria, South Africa, which were commissioned in October 2015 and July 2018, respectively.
+Added: The scientists at Klydon had constructed two ASP plants for the enrichment of oxygen-18 and Si-28 in Pretoria, South Africa, which were commissioned in October 2015 and July 2018, respectively.
We believe the success of the enrichment of oxygen-18 and silicon-28 has demonstrated the efficacy and commercial scalability of the ASP technology.
−Removed: We have completed the commissioning phase and are commencing commercial production at our Carbon-14 enrichment facility and our “multi-isotope” enrichment plant, which has its initial production run designated for enriched Silicon-28.
−Removed: We anticipate shipping the first commercial batches of enriched Carbon-14 in mid-2025 and enriched Silicon-28 during the second quarter of 2025.
−Removed: Quantum Enrichment Technology
+Added: We have completed the commissioning phase and are commencing commercial production at our C-14 enrichment facility and our “multi-isotope” enrichment plant, which has its initial production run designated for enriched Si-28.
+Added: We are targeting initial commercial shipments of enriched C-14 mid-2026 and initial commercial shipments of enriched Si-28 during the second quarter of 2026.
+Added: QE Technology
Isotopes of every element have unique spectroscopic “signatures” defined by the electromagnetic radiation or “light” absorbed by their atoms from electron transitions.
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Laser based isotope selective excitation followed by ionization and collection using electro-magnetic fields offers one of the most efficient techniques for isotope enrichment/denaturing.
−Removed: In the laser isotope separation (LIS) process, atoms of the target isotope in vapor stream get ionized after interaction with a tuned laser beam.
+Added: In the laser isotope separation process, atoms of the target isotope in
+Added: vapor stream get ionized after interaction with a tuned laser beam.
Ionized atoms are separated from the main vapor stream by electrostatic field.
−Removed: In our Quantum Enrichment facility, a resistive heating system has been designed to evaporate Ytterbium by sublimation at temperature in the range of 500 oC to 700 oC to provide adequate Yb vapor atoms for laser interaction.
+Added: In our Quantum Enrichment facility, a resistive heating system has been designed to evaporate Ytterbium by sublimation at temperature in the range of 500 o C to 700 o C to provide adequate Ytterbium vapor atoms for laser interaction.
During the process, the vapor jet comes out from the source to reach sonic speed at the exit plane, then it expands supersonically into vacuum.
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At the heart of laser-based isotope enrichment lies a proficient multi-step isotope selective photoionization scheme giving optimum selectivity and product yield.
−Removed: Yb has two valence electrons and very few transitions originating from its ground level.
+Added: Ytterbium has two valence electrons and very few transitions originating from its ground level.
Its ionization potential is 6.254eV.
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Dye lasers offer the best suitable choice for enrichment process as they suffice to all the requirements of the process like wavelength tunability, high power generation at high repetition rates.
−Removed: Diode Pumped Solid State Green Lasers (DPSSGLs) with ~3GHz line width in multi-mode operation are used to pump the dye lasers.
+Added: Diode Pumped Solid State Green Lasers with ~3GHz line width in multi-mode operation are used to pump the dye lasers.
The temporal delays between the pulses from the three lasers were arranged to ensure their sequential arrival in the interaction region with delay of several ns.
−Removed: We believe Quantum Enrichment technology is superior to AVLIS with optimized spectroscopy utilization and superior laser beam shaping.
+Added: We believe QE technology is superior to AVLIS with optimized spectroscopy utilization and superior laser beam shaping.
The key advantages include:
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However, PET equipment is more expensive and therefore not as widely available as SPECT equipment.
−Removed: Additionally, most PET tracers have short half-lives (e.g., nitrogen-13 (N-13):
−Removed: 10 minutes, carbon-11 (C-11):
+Added: Additionally, most PET tracers have short half-lives (e.g., Nitrogen-13:
+Added: 10 minutes, Carbon-11:
20 minutes, and F-18:
9 unchanged sentences
The different isotopes of carbon do not differ appreciably in their chemical properties.
−Removed: This resemblance is used in chemical and biological research, in a technique called carbon labelling:
−Removed: carbon-14 atoms can be used to replace nonradioactive carbon, in order to trace chemical and biochemical reactions involving carbon atoms from any given organic compound.
−Removed: Carbon-14 could be obtained from waste by-products in certain nuclear reactors.
−Removed: In June 2023, we entered into a multi-year supply agreement with a Canadian Customer for the supply of Carbon-14, which will be produced from our facility that was completed in March 2023.
−Removed: The customer agreed to supply carbon-14 in the form of carbon-dioxide gas as feedstock.
+Added: This resemblance is used in chemical and biological research, in a technique called carbon labeling:
+Added: C-14 atoms can be used to replace nonradioactive carbon, in order to trace chemical and biochemical reactions involving carbon atoms from any given organic compound.
+Added: C-14 could be obtained from waste by-products in certain nuclear reactors.
+Added: In June 2023, we entered into a multi-year supply agreement with a Canadian Customer for the supply of C-14, which will be produced from our facility that was completed in March 2023.
+Added: The customer agreed to supply C-14 in the form of carbon dioxide gas as feedstock.
We will then convert the carbon dioxide gas into methane under a chemical converting contract entered in June 2023.
3 unchanged sentences
The tolling agreement has a minimum “take or pay” amount of approximately $2.5 million per year, supported by a bank letter of guarantee.
−Removed: In September 2023, we entered into a Memorandum of Understanding (MOU) with the same customer to separate Deuterium and Tritium currently stored at nuclear sites within Canada.
−Removed: The timing and commercial implications of this MOU are subject to future agreement between the parties.
+Added: In September 2023, we entered into a Memorandum of Understanding with the same customer to separate Deuterium and Tritium currently stored at nuclear sites within Canada.
+Added: The timing and commercial implications of this Memorandum of Understanding are subject to future agreement between the parties.
ASP Technology for Silicon-28 Enrichment
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The lower the concentration of Si-29, the better a silicon quantum processor will perform in terms of computational power, accuracy and reliability.
−Removed: Unlike traditional centrifuges, which are suited to enriching gases with a high molecular mass, ASP Technology is highly suited to of enriching gases with a low molecular mass such as silane (SiH4), a gaseous compound that contains silicon.
+Added: Unlike traditional centrifuges, which are suited to enriching gases with a high molecular mass, ASP technology is highly suited to enriching gases with a low molecular mass such as silane (SiH4), a gaseous compound that contains silicon.
Quantum computers are expected to be thousands or millions of times more powerful than the most advanced of today’s conventional computers, opening new frontiers and opportunities in many industries, including medicine, artificial intelligence, cybersecurity, global logistics and global financial systems.
−Removed: We have entered into two purchase agreements for highly enriched Silicon-28.
+Added: We have entered into three purchase agreements for highly enriched Si-28.
The first is with a U.S.
1 unchanged sentence
The second is with a global industrial gas company.
−Removed: Quantum Enrichment Technology for Ytterbium-176 Enrichment
−Removed: Ytterbium-176 (“Yb-176”) is a stable isotope of ytterbium, that is commonly used to produce Lutetium-177 (“Lu-177”).
+Added: The third is with a large U.S.
+Added: QE Technology for Ytterbium-176 Enrichment
+Added: Yb-176 is a stable isotope of ytterbium, that is commonly used to produce Lutetium-177 (“Lu-177”).
Lu-177 is a medical isotope used in targeted radionuclide therapy for treating neuroendocrine tumors and prostate cancer.
3 unchanged sentences
The half-life also allows for transport over longer distances and on-site preparation of pharmaceuticals.
−Removed: Lu-177 can be produced in two ways, either directly by irradiation of lutetium-176 (“Lu-176”) or indirectly by irradiation of ytterbium-176 (“Yb-176”).
+Added: Lu-177 can be produced in two ways, either directly by irradiation of lutetium-176 (“Lu-176”) or indirectly by irradiation of Yb-176.
The irradiation of Lu-176 leads directly to Lu-177, while irradiation of Yb-176 will lead to the production of the short-lived intermediate radioisotope ytterbium-177 (“Yb-177”), which decays to Lu-177.
7 unchanged sentences
If it contains largely ‘useless’ Lu-176, the effectiveness of the treatment will diminish.
−Removed: The indirect method, where ytterbium-176 is irradiated, does not generate this extra isotope.
+Added: The indirect method, where Yb-176 is irradiated, does not generate this extra isotope.
The Lu-177 is produced in a matrix of ytterbium, which is separated from the lutetium by a chemical process after irradiation.
Therefore, it leads to Lu-177 no carrier added.
−Removed: In the indirect production route, Lu-177 differs from the target material Yb-176 and can be isolated chemically in no carrier added (“n.c.a.”) form.
−Removed: Quantum Enrichment Technology for Uranium Enrichment
−Removed: We believe our Quantum Enrichment technology is capable of enriching Uranium, which we may be able to commercialize as a nuclear fuel component for use in the new generation of HALEU-fueled small modular reactors that are now under development for commercial and government uses.
+Added: In the indirect production route, Lu-177 differs from the target material Yb-176 and can be isolated chemically in no carrier added form.
+Added: QE Technology for Uranium Enrichment
+Added: We believe our QE technology is capable of enriching Uranium, which we may be able to commercialize as a nuclear fuel component for use in the new generation of HALEU-fueled small modular reactors that are now under development for commercial and government uses.
Uranium is a naturally occurring element and is mined from deposits located in Kazakhstan, Canada, Australia, and several other countries including the United States.
1 unchanged sentence
In its natural state, uranium is principally comprised of two isotopes:
−Removed: uranium-235 (“U-235”) and uranium-238 (“U-238”).
+Added: U-235 and U-238.
The concentration of U-235 in natural uranium is only 0.711% by weight.
31 unchanged sentences
The World is Transitioning to Newer Smaller Reactors
−Removed: As the world transitions to a decarbonized electric grid, society is gradually decreasing its reliance on fossil fuels and increasing its reliance on “clean energy”.
−Removed: There appears to be bipartisan support for the growth of nuclear energy.
+Added: As the world transitions to a decarbonized electric grid, society is gradually decreasing its reliance on fossil fuels and increasing its reliance on “clean energy.” There appears to be bipartisan support for the growth of nuclear energy.
Nuclear power, through the operating light water reactor fleet and the deployment of advanced reactors, is poised to be an increasing contributor to carbon-free energy in the U.S.
22 unchanged sentences
Many advanced reactors, including the majority of the Advanced Reactor Demonstration Program awardees, will require HALEU, and fuel forms very different from those manufactured for the current Light Water Reactors (LWRs).
−Removed: For example, the current generation of LWRs uses fuel enriched to less than 5% uranium-235.
+Added: For example, the current generation of LWRs uses fuel enriched to less than 5% U-235.
In contrast, many advanced non-LWR designs require enrichments between 5% and 20% with most above 10%.
2 unchanged sentences
has mining, conversion, enrichment, fabrication, and transportation capability.
−Removed: However, the infrastructure for
−Removed: producing and utilizing HALEU, in particular enrichments above 10%, is not established in the U.S.
+Added: However, the infrastructure for producing and utilizing HALEU, in particular enrichments above 10%, is not established in the U.S.
The mining and conversion infrastructure are common to all enrichment levels.
27 unchanged sentences
• The data above does not include utilities that are considering enrichment between 5% and 10%.
−Removed: Quantum Enrichment Technology is ideally suited to the production of HALEU
−Removed: We believe that we are in a very different position to many of the entrenched domestic and international enrichers.
+Added: QE Technology is ideally suited to the production of HALEU
+Added: We believe that we are in a very different position compared to many of the entrenched domestic and international enrichers.
Our innovative isotope enrichment process has a number of advantages over traditional gas centrifuges and other novel approaches currently being explored by other companies:
cheaper in capital expenditures, faster in construction, more flexible in design and location.
−Removed: We estimate that the capital cost of constructing a Quantum Enrichment technology plant for uranium enrichment is approximately 75% cheaper than that of a traditional gas centrifuge enrichment facility.
+Added: We estimate that the capital cost of constructing a QE technology plant for uranium enrichment is approximately 75% cheaper than that of a traditional gas centrifuge enrichment facility.
Our manufacturing plants are modular, so our construction time is likely faster and more flexible than competing technologies.
1 unchanged sentence
Our operating costs of enriching uranium to 15.5% - 19.75% U-235 should be comparable to or cheaper than costs for other methods of uranium enrichment.
−Removed: The table below represents management’s estimated comparison of the Quantum Enrichment technology with a traditional gas centrifuge.
−Removed: Quantum Enrichment Technology Plant
+Added: The table below represents management’s estimated comparison of the QE technology with a traditional gas centrifuge.
+Added: QE Technology Plant
Gas Centrifuge
9 unchanged sentences
* for enrichment from 0.71% U235 to 5% U235
−Removed: We are in the process of commissioning and commencing commercial production at our Ytterbium-176 enrichment facility using the Quantum Enrichment technology in Pretoria, South Africa.
−Removed: We received a manufacturing permit for this facility from the South African DMRE during 3Q 2023.
−Removed: The construction of this plant will provide us with valuable experience in the construction of Quantum Enrichment technology facilities in the future.
−Removed: Many of the control systems, compressors, lasers and hardware used in a uranium enrichment facility would be similar to parts used in this ytterbium-176 enrichment facility.
+Added: We have completed the commissioning phase and producing commercial samples at our Yb-176 enrichment facility using the QE technology in Pretoria, South Africa.
+Added: This plant will provide us with valuable experience in the construction of QE technology facilities in the future.
+Added: Many of the control systems, compressors, lasers and hardware used in a uranium enrichment facility would be similar to parts used in this Yb-176 enrichment facility.
We expect the construction of a Uranium Enrichment facility would take approximately 30 months and the production volume would gradually ramp up to the final capacity of 20 metric tons per year.
−Removed: Importantly, subject to licensure, we believe we can produce commercial quantities of HALEU by 2027 to meet the anticipated demand from the advanced reactors currently in development.
+Added: Importantly, subject to licensure, we believe we can produce quantities of HALEU by 2027 for fuel testing and evaluation by developers of SMRs and other advanced reactors currently in development.
We believe that we can supply HALEU at a price lower than the HALEU currently imported from international enrichers and considerably lower than any potential domestic supply that may evolve.
+Added: In the period since our inception to date, we have not applied our enrichment technologies to the enrichment of U-235, nor received permission or regulatory approval to conduct testing of our enrichment technologies on uranium, except for the activities contemplated by the Services Contract with Necsa.
+Added: Our expectation that QLE’s initiative to apply our enrichment technologies to the enrichment of uranium could be successful is based upon research conducted by certain of our scientists prior to joining the company, as well as the demonstrated effectiveness of QE technology on Yb-176.
Intellectual Property
8 unchanged sentences
Regulatory Environment
−Removed: We are subject to a variety of laws and regulations, including but not limited to those of the United States and South Africa, that impose regulatory systems that govern many aspects of our operations, including our research and development activities involving the enrichment of isotopes in South Africa.
+Added: We are subject to a variety of laws and regulations, including but not limited to those of the United States and South Africa, that impose regulatory systems that govern many aspects of our operations, including our research and development activities
+Added: involving the enrichment of isotopes in South Africa.
In addition, these jurisdictions impose trade controls requirements that restrict trade to comply with applicable export controls and economic sanctions laws and requirements, and legal requirements that are intended to curtail bribery and corruption.
There are a number of regulators and treaties that govern and control our business and industry.
−Removed: The two principal ones that control and regulate the manufacturing of isotopes at our isotope enrichment facility in South Africa are the IAEA and the Nuclear Non-Proliferation Treaty (NPT).
+Added: The two principal ones that control and regulate the manufacturing of isotopes at our isotope enrichment facility in South Africa are the IAEA and the Nuclear Non-Proliferation Treaty (Treaty on Non-Proliferation of Nuclear Weapons) (“NPT").
The IAEA is an international organization that seeks to promote the peaceful use of nuclear energy, and to inhibit its use for any military purpose, including nuclear weapons.
5 unchanged sentences
These agreements can be viewed on the website of the IAEA ( https://www.iaea.org/resources/legal/country-factsheets ) and include agreements that govern the physical protection of nuclear material, the notification of nuclear accidents, assistance in the case of nuclear accidents, nuclear safety, civil liability, and technical cooperation.
−Removed: The Treaty on the Non-Proliferation of Nuclear Weapons, commonly known as the Non-Proliferation Treaty or NPT, is an international treaty whose objective is to prevent the spread of nuclear weapons and weapons technology, to promote cooperation in the peaceful uses of nuclear energy, and to further the goal of achieving nuclear disarmament and general and complete disarmament.
+Added: The NPT is an international treaty whose objective is to prevent the spread of nuclear weapons and weapons technology, to promote cooperation in the peaceful uses of nuclear energy, and to further the goal of achieving nuclear disarmament and general and complete disarmament.
Our South African subsidiary is registered with the South African Council for the Non-Proliferation of Weapons of Mass Destruction in terms of the Non-Proliferation of Weapons of Mass Destruction Act, 1993.
−Removed: Representatives from the South African Council for the Non-Proliferation of Weapons of Mass Destruction regularly inspect our facility and conduct tests to monitor the activities that are taking place at our facilities.
+Added: Representatives from the South African Council for the Non-Proliferation of Weapons of Mass Destruction regularly inspect our isotope enrichment facility and conduct tests to monitor the activities that are taking place at our isotope enrichment and production facilities.
In South Africa, government Notice 493 relates to nuclear-related dual-use equipment, materials and software and related technologies which can be used in their entirety or in part for the separation of uranium isotopes.
14 unchanged sentences
Many of our computer systems are not connected to the external internet and confidential information is secured at a controlled location.
−Removed: Some of our future isotopes may be regulated by healthcare regulators such as the FDA in the USA, Health Canada in Canada, the European Medicines Agency in Europe and similar regulators in other countries.
+Added: Some of our future isotopes may be regulated by healthcare regulators such as the U.S.
+Added: Food and Drug Administration (“FDA”) in the USA, Health Canada in Canada, the European Medicines Agency (“EMA”) in Europe and similar regulators in other countries.
laws restrict the ability of U.S.
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OFAC also administers U.S.
−Removed: sanctions against a lengthy list of entities and individuals, wherever they may be located, that the United States considers to be closely associated with these sanctioned countries or that are considered terrorists or traffickers in either narcotics or weapons of mass destruction.
+Added: sanctions against a lengthy list of entities and
+Added: individuals, wherever they may be located, that the United States considers to be closely associated with these sanctioned countries or that are considered terrorists or traffickers in either narcotics or weapons of mass destruction.
Furthermore, U.S.
2 unchanged sentences
restrictions or from facilitating transactions by non-U.S.
−Removed: those activities are forbidden to U.S.
+Added: persons if those activities are forbidden to U.S.
Penalties for violating provisions such as these can include significant civil and criminal fines, imprisonment and loss of tax credits or export privileges.
22 unchanged sentences
We consider our relationship with our employees to be good.
−Removed: We lease five facilities in Pretoria, South Africa for production, research and development and offices.
−Removed: One lease is under automatic monthly extensions and the other four leases have terms that expire between February 28, 2026 and December 31, 2030.
+Added: Our headquarters is located in leased offices in Dallas, Texas.
+Added: We lease facilities in Pretoria, South Africa and Hong Kong for production, research and development and offices.
+Added: One leases have terms that expire between September 30, 2026 and January 31, 2056.
We believe that our existing facilities are adequate to meet our current needs.
−Removed: Legal Proceedings
−Removed: Except as described herein, we are currently not party to, and our property is not currently the subject of any material pending legal matters or claims.
−Removed: On December 4, 2024, a purported stockholder of the Company filed a putative securities class action on behalf of purchasers of the Company’s securities between October 30, 2024 through November 26, 2024 against ASP Isotopes Inc.
−Removed: and certain of its executive officers in the United States District Court for the Southern District of New York ( Corredor v.
−Removed: ASP Isotopes Inc., et al.
−Removed: 1:24-cv-09253 (S.D.N.Y)) (the “Securities Class Action”).
−Removed: The Securities Class Action alleges that the Company, its chief executive officer and chief financial officer (“Defendants”) made materially misleading or false statements or omissions regarding
−Removed: the Company’s business and asserts purported claims under §§ 10(b) and 20(a) of the Securities Exchange Act of 1934 and SEC Rule 10b-5 promulgated thereunder.
−Removed: The complaint seeks unspecified compensatory damages, attorney’s fees and costs.
−Removed: Defendants intend to vigorously defend against the Securities Class Action;
−Removed: however, we cannot be certain of the outcome and, if decided adversely to us, our business and financial condition may be adversely affected.
−Removed: In addition to the matters described above, from time to time, we may become subject to arbitration, litigation or claims arising in the ordinary course of business.
−Removed: The results of any current or future claims or proceedings cannot be predicted with certainty, and regardless of the outcome, litigation can have an adverse impact on us because of defense and litigation costs, diversion of management resources, reputational harm and other factors.
+Added: Renergen has a lease for offices at Sandton Gate Office Park 7 Minerva Avenue, Glen Adrienne, Sandton, 2196 South Africa.
+Added: Tetra4 owns land on two farm properties in the Free State.
+Added: The total land size is 408.5897 hectares.
Compared sentence by sentence after normalising whitespace, quotation marks, case and digits, so re-formatting and restated figures do not read as changed language. Wording changes appear as one removal and one addition. The current filing and the prior one are authoritative.