The "safe" asset isn't always safe. From 1950 to 1981 — a long stretch of rising inflation and rising rates — long-term US government bonds lost more than half their value after adjusting for inflation, even though their stated (nominal) returns stayed positive the whole time.
Japanese stocks compounded at roughly 17% a year through the 1970s and nearly 29% a year through the 1980s — turning $10,000 in 1970 into about $610,000 by 1989. The bubble then burst so completely that the Nikkei 225 didn’t reclaim its December 1989 peak until February 2024, a 35-year round trip.
The only four-year losing streak in Dow history is the Great Depression: the index fell 17% in 1929, 34% in 1930, 53% in 1931, and 23% in 1932. 1931 remains the worst calendar year the Dow has ever recorded.